目的:对比肌骨超声影像引导高渗葡萄糖(hyperosmotic glucose,HG)与糖皮质激素(glucocorticoid,GC)注射治疗网球肘的疗效和安全性,为临床选择不同治疗方案提供参考。方法:收集2017年7月至2018年12月在中山大学附属第三医院康复科门诊行...目的:对比肌骨超声影像引导高渗葡萄糖(hyperosmotic glucose,HG)与糖皮质激素(glucocorticoid,GC)注射治疗网球肘的疗效和安全性,为临床选择不同治疗方案提供参考。方法:收集2017年7月至2018年12月在中山大学附属第三医院康复科门诊行肌骨超声影像引导注射治疗的网球肘患者,按注射药物不同分为HG组和GC组,对两组患者注射前、注射后1个月、注射后3个月、注射后6个月的疼痛视觉模拟评分(visual analogue scale,VAS)、Mayo肘关节功能评分(Mayo elbow performance score,MEPS)、臂、肩、手功能障碍(disabilities of the arm shoulder and hand,DASH)值和不良反应进行比较。结果:共纳入患者31例,患肘35例,HG组17例,GC组18例。与注射前相比,两组患者注射后1个月、3个月、6个月的VAS评分、MEPS评分和DASH值均显著改善(P<0.05)。GC组患者注射后1个月疗效显著,注射后3个月、6个月疗效维持;HG组注射后1个月疗效明显(P<0.05),注射后3个月疗效更优于注射后1个月(P<0.05),注射后6个月疗效维持。两组相比,注射后1个月、3个月、6个月的VAS评分、MEPS评分、DASH值,GC组较HG组改善更明显(P<0.05)。两组患者治疗后均未出现明显不良反应。结论:肌骨超声影像引导HG与GC注射治疗网球肘均安全、有效;注射后6个月内GC组的疗效优于HG组;该研究结果为网球肘的个体化治疗方案提供更多选择。展开更多
Quantum singular value thresholding(QSVT) algorithm,as a core module of many mathematical models,seeks the singular values of a sparse and low rank matrix exceeding a threshold and their associated singular vectors.Th...Quantum singular value thresholding(QSVT) algorithm,as a core module of many mathematical models,seeks the singular values of a sparse and low rank matrix exceeding a threshold and their associated singular vectors.The existing all-qubit QSVT algorithm demands lots of ancillary qubits,remaining a huge challenge for realization on nearterm intermediate-scale quantum computers.In this paper,we propose a hybrid QSVT(HQSVT) algorithm utilizing both discrete variables(DVs) and continuous variables(CVs).In our algorithm,raw data vectors are encoded into a qubit system and the following data processing is fulfilled by hybrid quantum operations.Our algorithm requires O [log(MN)] qubits with0(1) qumodes and totally performs 0(1) operations,which significantly reduces the space and runtime consumption.展开更多
文摘目的:对比肌骨超声影像引导高渗葡萄糖(hyperosmotic glucose,HG)与糖皮质激素(glucocorticoid,GC)注射治疗网球肘的疗效和安全性,为临床选择不同治疗方案提供参考。方法:收集2017年7月至2018年12月在中山大学附属第三医院康复科门诊行肌骨超声影像引导注射治疗的网球肘患者,按注射药物不同分为HG组和GC组,对两组患者注射前、注射后1个月、注射后3个月、注射后6个月的疼痛视觉模拟评分(visual analogue scale,VAS)、Mayo肘关节功能评分(Mayo elbow performance score,MEPS)、臂、肩、手功能障碍(disabilities of the arm shoulder and hand,DASH)值和不良反应进行比较。结果:共纳入患者31例,患肘35例,HG组17例,GC组18例。与注射前相比,两组患者注射后1个月、3个月、6个月的VAS评分、MEPS评分和DASH值均显著改善(P<0.05)。GC组患者注射后1个月疗效显著,注射后3个月、6个月疗效维持;HG组注射后1个月疗效明显(P<0.05),注射后3个月疗效更优于注射后1个月(P<0.05),注射后6个月疗效维持。两组相比,注射后1个月、3个月、6个月的VAS评分、MEPS评分、DASH值,GC组较HG组改善更明显(P<0.05)。两组患者治疗后均未出现明显不良反应。结论:肌骨超声影像引导HG与GC注射治疗网球肘均安全、有效;注射后6个月内GC组的疗效优于HG组;该研究结果为网球肘的个体化治疗方案提供更多选择。
基金Project supported by the Key Research and Development Program of Guangdong Province,China(Grant No.2018B030326001)the National Natural Science Foundation of China(Grant Nos.61521001,12074179,and 11890704)。
文摘Quantum singular value thresholding(QSVT) algorithm,as a core module of many mathematical models,seeks the singular values of a sparse and low rank matrix exceeding a threshold and their associated singular vectors.The existing all-qubit QSVT algorithm demands lots of ancillary qubits,remaining a huge challenge for realization on nearterm intermediate-scale quantum computers.In this paper,we propose a hybrid QSVT(HQSVT) algorithm utilizing both discrete variables(DVs) and continuous variables(CVs).In our algorithm,raw data vectors are encoded into a qubit system and the following data processing is fulfilled by hybrid quantum operations.Our algorithm requires O [log(MN)] qubits with0(1) qumodes and totally performs 0(1) operations,which significantly reduces the space and runtime consumption.