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Nutritional Status of Under-five Children from Urban Low-income Families in Xiangtan and Jilin in China 被引量:1
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作者 郭琰芳 甘银燕 +2 位作者 郭超男 孙菊 郝丽萍 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2017年第1期74-78,共5页
There have been many studies on the nutrition and the growth status of children from rural and remote western regions of China, whereas researches on children from urban low-income families are scarce. This study aime... There have been many studies on the nutrition and the growth status of children from rural and remote western regions of China, whereas researches on children from urban low-income families are scarce. This study aimed to investigate the growth and nutritional status of children under five years of age from urban low-income families in China. There were 169 children aged 25–60 months recruited from Xiangtan and Jilin, two cities with a population of 2.81 million and 4.26 million respectively, in China in this cluster cross-sectional study. Data were collected on demographic and socioeconomic characteristics, the feeding practices and the incidence of anemia and diarrhea. The results showed that the prevalence of low birth weight and macrosomia was 7.1% and 9.5% for the two cities, respectively, which was higher than that for other cities in China(1.5% and 5.9%). Of all the sampled children, 14.6% and 8.2% suffered anemia and diarrhea, respectively. Multivariate analysis showed that legumes or nuts fed in a 24-h recall increased the risk of anemia(OR=4.9). Children whose caregivers began to introduce complementary foods relatively late would have high diarrhea prevalence(OR=1.4). In conclusion, the prevalence of anemia and diarrhea in under-five children from urban low-income families in China is relatively high. The growth and nutritional status of these children is greatly affected by feeding practices. A series of measures should be taken by relevant government departments to improve the health of these children. 展开更多
关键词 家庭收入 中国西部 营养状况 儿童 吉林 湘潭 LOW 中国城市
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ALDH2在白藜芦醇改善大鼠慢性酒精性肝损伤中的机制 被引量:6
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作者 黄丙清 邱香 +3 位作者 王林枝 朱腾世 郭琰芳 郝丽萍 《华中科技大学学报(医学版)》 CAS CSCD 北大核心 2015年第1期37-41,共5页
目的探讨酒精代谢酶乙醇脱氢酶(ADH)和乙醛脱氢酶2(ALDH2)在白藜芦醇(resveratrol,Res)改善大鼠慢性酒精性肝损伤中的机制。方法采用含酒精的Lieber-DeCarli液体饲料喂养大鼠19周,建立慢性酒精性肝损伤模型。42只SD大鼠随机分成正常对照... 目的探讨酒精代谢酶乙醇脱氢酶(ADH)和乙醛脱氢酶2(ALDH2)在白藜芦醇(resveratrol,Res)改善大鼠慢性酒精性肝损伤中的机制。方法采用含酒精的Lieber-DeCarli液体饲料喂养大鼠19周,建立慢性酒精性肝损伤模型。42只SD大鼠随机分成正常对照组,低、中、高剂量酒精组,Res对照组,高剂量酒精+Res组。采用苏木精-伊红(HE)和油红O染色,观察肝组织形态学改变;采用试剂盒测定肝组织中ADH、ALDH2的活性;Western blot检测肝组织中ADH与ALDH2的蛋白表达。结果各剂量酒精组大鼠肝组织脂肪变性和炎症浸润明显,体重和能量摄入量与正常对照组相比下降,差异具有统计学意义(P<0.05或P<0.01);且肝组织ADH活性与蛋白表达略有升高,而肝组织ALDH2活性与蛋白表达显著下降。Res干预后大鼠肝组织脂肪变性和炎症浸润均较高剂量酒精组显著减轻,体重与能量摄入量增加,显著提升了肝组织中ALDH2的活性与蛋白表达(P<0.05)。结论 Res可能通过对大鼠肝脏ALDH2的调节来改善慢性酒精摄入引起的肝脏损伤。 展开更多
关键词 酒精性肝损伤 白藜芦醇 乙醇脱氢酶 乙醛脱氢酶2
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