The research explored the extraction techniques of organic solvents of Antarctic kril oil and the effects of freezing temperature, extractant proportion, ex-traction time, drying temperature and ratio of material and ...The research explored the extraction techniques of organic solvents of Antarctic kril oil and the effects of freezing temperature, extractant proportion, ex-traction time, drying temperature and ratio of material and liquid on extraction ratio of Antarctic kril oil. Based on single-factor experiments, optimal extraction conditions were concluded as per response surface methodology, as fol ows： freezing tempera-ture at -38.5 ℃, the ratio of material and liquid at 1 g：6.7 ml, and drying tempera-ture at 66.8 ℃, where the yield rate of crude oil reached 13.71%.展开更多
目的探究原发性肝癌患者术前营养相关指标与患者主观整体评估(patient⁃generated subjective global assess⁃ment,PG⁃SGA)评分之间的相关性。方法选取2016年12月至2017年3月海军军医大学附属东方肝胆外科医院的120例肝癌患者为研究对象...目的探究原发性肝癌患者术前营养相关指标与患者主观整体评估(patient⁃generated subjective global assess⁃ment,PG⁃SGA)评分之间的相关性。方法选取2016年12月至2017年3月海军军医大学附属东方肝胆外科医院的120例肝癌患者为研究对象,根据PG⁃SGA量表将其分成营养不良组(PG⁃SGA评分≥4分)76例和非营养不良组(PG⁃SGA评分<4分)44例。检测2组多项术前营养相关指标,与PG⁃SGA评分进行相关性分析,并使用受试者工作特征(receiver operating character⁃istic,ROC)曲线预测诊断价值。结果120例患者中营养不良率为63.3%。营养不良组患者血液视黄醇结合蛋白(retinol⁃binding protein,RBP)为(23.2±10.8)mg/L、前白蛋白(prealbumin,PA)为(122.8±44.7)mg/L、肌酐(creatinine,Cr)为(57.9±12.5)mol/L、体质量指数(body mass index,BMI)为23.2±3.4,均显著低于非营养不良组[分别为(45.9±14.9)mg/L、(252.7±51.8)mg/L、(80.7±13.6)mol/L、25.7±3.2],差异均具有统计学意义(P<0.001)。原发性肝癌患者术前PG⁃SGA评分与RBP(r=-0.526,P<0.001)、PA(r=-0.636,P<0.001)、Cr(r=-0.612,P<0.001)及BMI(r=-0.219,P=0.016)均存在负相关关系;通过ROC曲线发现RBP(AUC=0.925,P<0.001)、PA(AUC=0.979,P<0.001)、Cr(AUC=0.906,P<0.001)和BMI(AUC=0.701,P<0.001)均有较好的诊断价值。结论原发性肝癌患者术前营养不良发生率较高。BMI以及血液RBP、PA、Cr与PG⁃SGA评分存在负相关,对肝癌患者术前的营养不良有诊断价值。展开更多
基金Supported by Postgraduate Scientific Research Foundation(A-2500-11-0079)Shanghai Engineering Research Center of Aquatic-Product Processing&Preservation Foundation(11DZ2280300)Aquaculture Genetics and Breeding Technology Center in Shanghai Ocean University(ZF1206)~~
文摘The research explored the extraction techniques of organic solvents of Antarctic kril oil and the effects of freezing temperature, extractant proportion, ex-traction time, drying temperature and ratio of material and liquid on extraction ratio of Antarctic kril oil. Based on single-factor experiments, optimal extraction conditions were concluded as per response surface methodology, as fol ows： freezing tempera-ture at -38.5 ℃, the ratio of material and liquid at 1 g：6.7 ml, and drying tempera-ture at 66.8 ℃, where the yield rate of crude oil reached 13.71%.
文摘目的探究原发性肝癌患者术前营养相关指标与患者主观整体评估(patient⁃generated subjective global assess⁃ment,PG⁃SGA)评分之间的相关性。方法选取2016年12月至2017年3月海军军医大学附属东方肝胆外科医院的120例肝癌患者为研究对象,根据PG⁃SGA量表将其分成营养不良组(PG⁃SGA评分≥4分)76例和非营养不良组(PG⁃SGA评分<4分)44例。检测2组多项术前营养相关指标,与PG⁃SGA评分进行相关性分析,并使用受试者工作特征(receiver operating character⁃istic,ROC)曲线预测诊断价值。结果120例患者中营养不良率为63.3%。营养不良组患者血液视黄醇结合蛋白(retinol⁃binding protein,RBP)为(23.2±10.8)mg/L、前白蛋白(prealbumin,PA)为(122.8±44.7)mg/L、肌酐(creatinine,Cr)为(57.9±12.5)mol/L、体质量指数(body mass index,BMI)为23.2±3.4,均显著低于非营养不良组[分别为(45.9±14.9)mg/L、(252.7±51.8)mg/L、(80.7±13.6)mol/L、25.7±3.2],差异均具有统计学意义(P<0.001)。原发性肝癌患者术前PG⁃SGA评分与RBP(r=-0.526,P<0.001)、PA(r=-0.636,P<0.001)、Cr(r=-0.612,P<0.001)及BMI(r=-0.219,P=0.016)均存在负相关关系;通过ROC曲线发现RBP(AUC=0.925,P<0.001)、PA(AUC=0.979,P<0.001)、Cr(AUC=0.906,P<0.001)和BMI(AUC=0.701,P<0.001)均有较好的诊断价值。结论原发性肝癌患者术前营养不良发生率较高。BMI以及血液RBP、PA、Cr与PG⁃SGA评分存在负相关,对肝癌患者术前的营养不良有诊断价值。
