基金supported by the National Key R&D Program of China(2022YFA1304000)the National Natural Science Foundation of China(81972823)+3 种基金the Foundation for Innovative Research Groups of the National Natural Science Foundation of China(32121004)the Guangdong Special Support Program innovation team(2019BT02N054)the Open Research Fund of State Key Laboratory of Cellular Stress Biology,Xiamen University(SKLCSB2019KF013)the Fundamental Research Funds for the Central University(20720220003)。