为提高集群资源使用效率,管理员需要对用户进行分类,从而对不同用户提出资源使用策略。DBSCAN(Density Based Spatial Clustering of Applications with Noise)聚类算法可对用户进行分类,但对初始参数敏感。为此,提出改进算法,首先将密...为提高集群资源使用效率,管理员需要对用户进行分类,从而对不同用户提出资源使用策略。DBSCAN(Density Based Spatial Clustering of Applications with Noise)聚类算法可对用户进行分类,但对初始参数敏感。为此,提出改进算法,首先将密度进行层次划分,由此得出各层次的密度阈值,在每种阈值下采用DBSCAN算法,解决全局参数问题。在此基础上,创新地使用一个直接可达距离排序队列,将排序信息作为可变参数,减小初始参数对结果的影响。通过高性能计算中心用户数据的实例验证了其可行性。实验结果表明,改进后的算法提高了用户分类的准确性和全面性。展开更多
This study explored the possibility that the components in melanoma cytoplasm induce murine BMSCs transformation and expression of Melan-A by morphologically observing the changes of BMSCs and immunocytochemically det...This study explored the possibility that the components in melanoma cytoplasm induce murine BMSCs transformation and expression of Melan-A by morphologically observing the changes of BMSCs and immunocytochemically detecting Melan-A in the cells after culturing BMSCs in me-dium containing melanoma cytoplasm components （MCC）. MCC of B16 melanoma cells was prepared and BMSCs were cultured and induced by adding the MCC into culture medium. The cells were morphologically observed and Melan-A was immunohistochemically detected to confirm BMSCs transformation. MCC-induced BMSCs underwent morphological changes. A number of melanin granules appeared in the cytoplasm of the cells and some were released into surrounding areas. Several cells that might come from one cell formed a cluster, and their granules, together with those secreted by other induced BMSCs, formed a so-called ＂sphere-formed structure＂. The induced BMSCs expressed Melan-A. We are led to conclude that there might be some factors in the cytoplasm of melanoma cells that might induce BMSCs transformation toward melanogenic cell, or even melanoma.展开更多
文摘为提高集群资源使用效率,管理员需要对用户进行分类,从而对不同用户提出资源使用策略。DBSCAN(Density Based Spatial Clustering of Applications with Noise)聚类算法可对用户进行分类,但对初始参数敏感。为此,提出改进算法,首先将密度进行层次划分,由此得出各层次的密度阈值,在每种阈值下采用DBSCAN算法,解决全局参数问题。在此基础上,创新地使用一个直接可达距离排序队列,将排序信息作为可变参数,减小初始参数对结果的影响。通过高性能计算中心用户数据的实例验证了其可行性。实验结果表明,改进后的算法提高了用户分类的准确性和全面性。
基金supported by a grant from the National Natural Sciences Foundation of China (No. 30770942)
文摘This study explored the possibility that the components in melanoma cytoplasm induce murine BMSCs transformation and expression of Melan-A by morphologically observing the changes of BMSCs and immunocytochemically detecting Melan-A in the cells after culturing BMSCs in me-dium containing melanoma cytoplasm components （MCC）. MCC of B16 melanoma cells was prepared and BMSCs were cultured and induced by adding the MCC into culture medium. The cells were morphologically observed and Melan-A was immunohistochemically detected to confirm BMSCs transformation. MCC-induced BMSCs underwent morphological changes. A number of melanin granules appeared in the cytoplasm of the cells and some were released into surrounding areas. Several cells that might come from one cell formed a cluster, and their granules, together with those secreted by other induced BMSCs, formed a so-called ＂sphere-formed structure＂. The induced BMSCs expressed Melan-A. We are led to conclude that there might be some factors in the cytoplasm of melanoma cells that might induce BMSCs transformation toward melanogenic cell, or even melanoma.
