<strong>Background:</strong><span><span><span style="font-family:""><span style="font-family:Verdana;"> Group B </span><i><span style="f...<strong>Background:</strong><span><span><span style="font-family:""><span style="font-family:Verdana;"> Group B </span><i><span style="font-family:Verdana;">Streptococcus </span></i><span style="font-family:Verdana;">(GBS) is a major cause of bacterial infections in the perinatal period, of which colonization prevalence among Northern-Nigerian pregnant women is scarce. We attempted to determine </span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">1</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">) its prevalence</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">,</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">2</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">) risk factors for GBS colonization and </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">3</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">) drugs-susceptibility.</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family:Verdana;">Methodology:</span></b></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> This cross-sectional study involved 185 pregnant women between 35</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">-</span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">37 weeks of gestation at tertiary health center of Sokoto, Nigeria. </span><span style="font-family:Verdana;">Vaginal/rectal swabs were collected, were cultured for GBS and tested for drug-</span><span style="font-family:Verdana;">susceptibilities. The study was conducted between December, 2017 and April, </span><span style="font-family:Verdana;">2018.</span></span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family:Verdana;">Results:</span></b></span></span><span><span><span style="font-family:""> <a name="_Toc14800008"></a><span style="font-family:Verdana;">One hundred and eighty five (185) pregnant women participated </span></span></span></span><span><span><span><span style="font-family:""><span style="font-family:Verdana;">in this study. GBS vaginal-colonization-rate was 3.8% (7/185). A significance relationship was observed between GBS-colonization and socio-economic class, as 57.10% (4/7) of the GBS positive women were of low-socio economic class (</span><i><span style="font-family:Verdana;">p</span></i><span style="font-family:Verdana;"> 0.035). No associations were observed between GBS-colonization and the followings: maternal age, parity, poor obstetric outcome-history. All the 7 GBS positive cultures were sensitive to Clindamycin. One was sensitive to both Clindamycin and Ceftriaxone. None was sensitive to Penicillin. </span><b><span style="font-family:Verdana;">Conclusion</span></b></span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family:Verdana;">:</span></b></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> The prevalence of GBS colonization was low in this area. Maternal socio-economic class is found to be a risk of GBS-colonization.</span></span></span>展开更多
文摘<strong>Background:</strong><span><span><span style="font-family:""><span style="font-family:Verdana;"> Group B </span><i><span style="font-family:Verdana;">Streptococcus </span></i><span style="font-family:Verdana;">(GBS) is a major cause of bacterial infections in the perinatal period, of which colonization prevalence among Northern-Nigerian pregnant women is scarce. We attempted to determine </span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">1</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">) its prevalence</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">,</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">2</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">) risk factors for GBS colonization and </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">3</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">) drugs-susceptibility.</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family:Verdana;">Methodology:</span></b></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> This cross-sectional study involved 185 pregnant women between 35</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">-</span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">37 weeks of gestation at tertiary health center of Sokoto, Nigeria. </span><span style="font-family:Verdana;">Vaginal/rectal swabs were collected, were cultured for GBS and tested for drug-</span><span style="font-family:Verdana;">susceptibilities. The study was conducted between December, 2017 and April, </span><span style="font-family:Verdana;">2018.</span></span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family:Verdana;">Results:</span></b></span></span><span><span><span style="font-family:""> <a name="_Toc14800008"></a><span style="font-family:Verdana;">One hundred and eighty five (185) pregnant women participated </span></span></span></span><span><span><span><span style="font-family:""><span style="font-family:Verdana;">in this study. GBS vaginal-colonization-rate was 3.8% (7/185). A significance relationship was observed between GBS-colonization and socio-economic class, as 57.10% (4/7) of the GBS positive women were of low-socio economic class (</span><i><span style="font-family:Verdana;">p</span></i><span style="font-family:Verdana;"> 0.035). No associations were observed between GBS-colonization and the followings: maternal age, parity, poor obstetric outcome-history. All the 7 GBS positive cultures were sensitive to Clindamycin. One was sensitive to both Clindamycin and Ceftriaxone. None was sensitive to Penicillin. </span><b><span style="font-family:Verdana;">Conclusion</span></b></span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family:Verdana;">:</span></b></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> The prevalence of GBS colonization was low in this area. Maternal socio-economic class is found to be a risk of GBS-colonization.</span></span></span>
