This was an outlook on the prediction of the infrared laser potentiality from concentration dependences of the 2F5/2 experimental decay time in Yb3+-doped solid-state crystals mainly on cubic crystals with 99.99% puri...This was an outlook on the prediction of the infrared laser potentiality from concentration dependences of the 2F5/2 experimental decay time in Yb3+-doped solid-state crystals mainly on cubic crystals with 99.99% purity which could be extended to laser ceramics of the same composition.展开更多
BACKGROUND Colorectal neuroendocrine carcinoma (NEC) is a rare tumor that demonstrates aggressive growth pattern with ingrowth into the tract, metastasis to the other organs, and invasion to the surrounding organs;the...BACKGROUND Colorectal neuroendocrine carcinoma (NEC) is a rare tumor that demonstrates aggressive growth pattern with ingrowth into the tract, metastasis to the other organs, and invasion to the surrounding organs;these clinical characteristics result in poor prognosis. Surgical resection appears as an effective approach;however, because it is difficult to accurately diagnose NEC during the early stage and owing to its aggressive growth pattern, development of a reliable standard chemotherapy regimen and management strategies are essential. CASE SUMMARY Here, we report the case of patient with NEC showing an aggressive growth pattern that resulted in the rupture of the tumor to the outside the colon after stenting of the internal colonic stenosis. In addition, the tumor invaded into the duodenum, thereby causing duodenal stenosis that required an additional stent in the duodenum. This aggressive growth pattern is one of the main features of the NEC that is different from adenocarcinoma. To clarify the clinical characteristics, we reviewed 60 recently reported cases, including data on tumor location, size, treatment, and prognosis. CONCLUSION We consider that the information presented here is of great significance for the diagnosis, treatment, and management of symptoms of the patients with NEC.展开更多
HfO_2/α-Al_2_O_3 eutectics were grown by the micro-pulling down(μ-PD) method at the composition of 63.2 mol.% α-Al_2_O_3, 35.512 mol.% HfO_2, 0.92 mol.% Eu_2O_3 and 0.368 mol.% Y_2O_3. Rod phases with around 3–4 ...HfO_2/α-Al_2_O_3 eutectics were grown by the micro-pulling down(μ-PD) method at the composition of 63.2 mol.% α-Al_2_O_3, 35.512 mol.% HfO_2, 0.92 mol.% Eu_2O_3 and 0.368 mol.% Y_2O_3. Rod phases with around 3–4 μm diameter were observed on the transverse cross-section. The phase-separated scintillator fibers(PSSFs) structure with fibers of around 3–4 μm diameter and 10–20 μm length was observed. The electron back scattering patterns indicated crystal orientation of [101] for monoclinic HfO_2 rod phase and [0001] for α-Al_2_O_3 matrix in the transverse cross-section. Eu^(3+) 4f-4f emission was observed at 550–750 nm.展开更多
文摘This was an outlook on the prediction of the infrared laser potentiality from concentration dependences of the 2F5/2 experimental decay time in Yb3+-doped solid-state crystals mainly on cubic crystals with 99.99% purity which could be extended to laser ceramics of the same composition.
文摘BACKGROUND Colorectal neuroendocrine carcinoma (NEC) is a rare tumor that demonstrates aggressive growth pattern with ingrowth into the tract, metastasis to the other organs, and invasion to the surrounding organs;these clinical characteristics result in poor prognosis. Surgical resection appears as an effective approach;however, because it is difficult to accurately diagnose NEC during the early stage and owing to its aggressive growth pattern, development of a reliable standard chemotherapy regimen and management strategies are essential. CASE SUMMARY Here, we report the case of patient with NEC showing an aggressive growth pattern that resulted in the rupture of the tumor to the outside the colon after stenting of the internal colonic stenosis. In addition, the tumor invaded into the duodenum, thereby causing duodenal stenosis that required an additional stent in the duodenum. This aggressive growth pattern is one of the main features of the NEC that is different from adenocarcinoma. To clarify the clinical characteristics, we reviewed 60 recently reported cases, including data on tumor location, size, treatment, and prognosis. CONCLUSION We consider that the information presented here is of great significance for the diagnosis, treatment, and management of symptoms of the patients with NEC.
基金Project supported by the Funding Program for Next Generation World-Leading Researchers,JSPS,Development of Systems and Technology for Advanced Measurement and Analysis,Japan Science and Technology Agency (JST),Adaptable & Seamless Technology Transfer Program through Target-driven R&D (A-STEP),JST,Japan Society for the Promotion of Science (JSPS) Grant-in-Aid for Exploratory Research,JSPS Research Fellowships for Young Scientists,the Health Labour Sciences Research Grant,the Ministry of Health Labour and Welfare and Czech MEYS KONTAKT Cz-jp Collaboration LH14266 Project,Crystal Clear Collaboration in CERN,and EC Marie Curie Initial Training Network LUMINET (316906)
文摘HfO_2/α-Al_2_O_3 eutectics were grown by the micro-pulling down(μ-PD) method at the composition of 63.2 mol.% α-Al_2_O_3, 35.512 mol.% HfO_2, 0.92 mol.% Eu_2O_3 and 0.368 mol.% Y_2O_3. Rod phases with around 3–4 μm diameter were observed on the transverse cross-section. The phase-separated scintillator fibers(PSSFs) structure with fibers of around 3–4 μm diameter and 10–20 μm length was observed. The electron back scattering patterns indicated crystal orientation of [101] for monoclinic HfO_2 rod phase and [0001] for α-Al_2_O_3 matrix in the transverse cross-section. Eu^(3+) 4f-4f emission was observed at 550–750 nm.
