Situated at the intersection of technology and medicine,the Internet of Things(IoT)holds the promise of addressing some of healthcare's most pressing challenges,from medical error,to chronic drug shortages,to over...Situated at the intersection of technology and medicine,the Internet of Things(IoT)holds the promise of addressing some of healthcare's most pressing challenges,from medical error,to chronic drug shortages,to overburdened hospital systems,to dealing with the COVID-19 pandemic.However,despite considerable recent technological advances,the pace of successful implementation of promising IoT healthcare initiatives has been slow.To inspire more productive collaboration,we present here a simple—but surprisingly underrated—problemoriented approach to developing healthcare technologies.To further assist in this effort,we reviewed the various commercial,regulatory,social/cultural,and technological factors in the development of the IoT.We propose that fog computing—a technological paradigm wherein the burden of computing is shifted from a centralized cloud server closer to the data source—offers the greatest promise for building a robust and scalable healthcare IoT ecosystem.To this end,we explore the key enabling technologies that underpin the fog architecture,from the sensing layer all the way up to the cloud.It is our hope that ongoing advances in sensing,communications,cryptography,storage,machine learning,and artificial intelligence will be leveraged in meaningful ways to generate unprecedented medical intelligence and thus drive improvements in the health of many people.展开更多
Ischemic stroke represents a significant danger to human beings,especially the elderly.Interventions are only available to remove the clot,and the mechanism of neuronal death during ischemic stroke is still in debate....Ischemic stroke represents a significant danger to human beings,especially the elderly.Interventions are only available to remove the clot,and the mechanism of neuronal death during ischemic stroke is still in debate.Ferroptosis is increasingly appreciated as a mechanism of cell death after ischemia in various organs.展开更多
基金supported in part by a grant from the Victoria-Jiangsu Program for Technology and Innovation Research and Development。
文摘Situated at the intersection of technology and medicine,the Internet of Things(IoT)holds the promise of addressing some of healthcare's most pressing challenges,from medical error,to chronic drug shortages,to overburdened hospital systems,to dealing with the COVID-19 pandemic.However,despite considerable recent technological advances,the pace of successful implementation of promising IoT healthcare initiatives has been slow.To inspire more productive collaboration,we present here a simple—but surprisingly underrated—problemoriented approach to developing healthcare technologies.To further assist in this effort,we reviewed the various commercial,regulatory,social/cultural,and technological factors in the development of the IoT.We propose that fog computing—a technological paradigm wherein the burden of computing is shifted from a centralized cloud server closer to the data source—offers the greatest promise for building a robust and scalable healthcare IoT ecosystem.To this end,we explore the key enabling technologies that underpin the fog architecture,from the sensing layer all the way up to the cloud.It is our hope that ongoing advances in sensing,communications,cryptography,storage,machine learning,and artificial intelligence will be leveraged in meaningful ways to generate unprecedented medical intelligence and thus drive improvements in the health of many people.
基金This work was supported by the National Key Research and Development Project of China(2018YFC1312300)the National Natural Science Foundation of China(81722016,81801182)+2 种基金he program of National Clinical Research Center for Geriatrics of West China Hospital(Z2021LC001,Z20191001)West China Hospital 1.3.5 project for disciplines of excellence(ZYYC20007,ZYYC20009)Sichuan University postdoctoral interdisciplinary Innovation Fund.
文摘Ischemic stroke represents a significant danger to human beings,especially the elderly.Interventions are only available to remove the clot,and the mechanism of neuronal death during ischemic stroke is still in debate.Ferroptosis is increasingly appreciated as a mechanism of cell death after ischemia in various organs.
