Hydrogel-based tissue-engineered skin has attracted increased attention due to its potential to restore the structural integrity and functionality of skin.However,the mechanical properties of hydrogel scaffolds and na...Hydrogel-based tissue-engineered skin has attracted increased attention due to its potential to restore the structural integrity and functionality of skin.However,the mechanical properties of hydrogel scaffolds and natural skin are substantially different.Here,we developed a polyvinyl alcohol(PVA)/acrylamide based interpenetrating network(IPN)hydrogel that was surface modified with polydopamine(PDA)and termed Dopa-gel.The Dopa-gel exhibited mechanical properties similar to native skin tissue and a superior ability to modulate paracrine functions.Furthermore,a tough scaffold with tensile resistance was fabricated using this hydrogel by three-dimensional printing.The results showed that the interpenetration of PVA,alginate,and polyacrylamide networks notably enhanced the mechanical properties of the hydrogel.Surface modification with PDA endowed the hydrogels with increased secretion of immunomodulatory and proangiogenic factors.In an in vivo model,Dopa-gel treatment accelerated wound closure,increased vascularization,and promoted a shift in macrophages from a proinflammatory M1 phenotype to a prohealing and anti-inflammatory M2 phenotype within the wound area.Mechanistically,the focal adhesion kinase(FAK)/extracellular signal-related kinase(ERK)signaling pathway may mediate the promotion of skin defect healing by increasing paracrine secretion via the Dopa-gel.Additionally,proangiogenic factors can be induced through Rho-associated kinase-2(ROCK-2)/vascular endothelial growth factor(VEGF)-mediated paracrine secretion under tensile stress conditions.Taken together,these findings suggest that the multifunctional Dopa-gel,which has good mechanical properties similar to those of native skin tissue and enhanced immunomodulatory and angiogenic properties,is a promising scaffold for skin tissue regeneration.展开更多
For the ASO-S/HXI payload, the accuracy of the flare reconstruction is reliant on important factors such as the alignment of the dual grating and the precise measurement of observation orientation. To guarantee optima...For the ASO-S/HXI payload, the accuracy of the flare reconstruction is reliant on important factors such as the alignment of the dual grating and the precise measurement of observation orientation. To guarantee optimal functionality of the instrument throughout its life cycle, the Solar Aspect System (SAS) is imperative to ensure that measurements are accurate and reliable. This is achieved by capturing the target motion and utilizing a physical model-based inversion algorithm. However, the SAS optical system’s inversion model is a typical ill-posed inverse problem due to its optical parameters, which results in small target sampling errors triggering unacceptable shifts in the solution. To enhance inversion accuracy and make it more robust against observation errors, we suggest dividing the inversion operation into two stages based on the SAS spot motion model. First, the as-rigid-aspossible (ARAP) transformation algorithm calculates the relative rotations and an intermediate variable between the substrates. Second, we solve an inversion linear equation for the relative translation of the substrates, the offset of the optical axes, and the observation orientation. To address the ill-posed challenge, the Tikhonov method grounded on the discrepancy criterion and the maximum a posteriori (MAP) method founded on the Bayesian framework are utilized. The simulation results exhibit that the ARAP method achieves a solution with a rotational error of roughly±3 5 (1/2-quantile);both regularization techniques are successful in enhancing the stability of the solution, the variance of error in the MAP method is even smaller—it achieves a translational error of approximately±18μm (1/2-quantile) in comparison to the Tikhonov method’s error of around±24μm (1/2-quantile). Furthermore, the SAS practical application data indicates the method’s usability in this study. Lastly, this paper discusses the intrinsic interconnections between the regularization methods.展开更多
The discovery of intrinsically disordered proteins （IDP） （i.e., biologically active proteins that do not possess stable secondary and/or tertiary structures） came as an unexpected surprise, as the existence of suc...The discovery of intrinsically disordered proteins （IDP） （i.e., biologically active proteins that do not possess stable secondary and/or tertiary structures） came as an unexpected surprise, as the existence of such proteins is in contradiction to the traditional ＂sequence →structure →function＂ paradigm. Accurate prediction of a protein＇s predisposition to be intrinsically disordered is a necessary prerequisite for the further understanding of principles and mechanisms of protein folding and function, and is a key for the elaboration of a new structural and functional hierarchy of proteins. Therefore, prediction of IDPs has attracted the attention of many researchers, and a number of prediction tools have been developed. Predictions of disorder, in turn, are playing major roles in directing laboratory experiments that are leading to the discovery of ever more disordered proteins, and thereby leading to a positive feedback loop in the investigation of these proteins. In this review of algorithms for intrinsic disorder prediction, the basic concepts of various prediction methods for IDPs are summarized, the strengths and shortcomings of many of the methods are analyzed, and the difficulties and directions of future development of IDP prediction techniques are discussed.展开更多
The terrain camera （TCAM） and panoramic camera （PCAM） are two of the major scientific payloads installed on the lander and rover of the Chang＇e 3 mission re- spectively. They both use a Bayer color filter array c...The terrain camera （TCAM） and panoramic camera （PCAM） are two of the major scientific payloads installed on the lander and rover of the Chang＇e 3 mission re- spectively. They both use a Bayer color filter array covering CMOS sensor to capture color images of the Moon＇s surface. RGB values of the original images are related to these two kinds of cameras. There is an obvious color difference compared with human visual perception. This paper follows standards published by the International Commission on Illumination to establish a color correction model, designs the ground calibration experiment and obtains the color correction coefficient. The image qual- ity has been significantly improved and there is no obvious color difference in the corrected images. Ground experimental results show that： （1） Compared with uncor- rected images, the average color difference of TCAM is 4.30, which has been reduced by 62.1%. （2） The average color differences of the left and right cameras in PCAM are 4.14 and 4.16, which have been reduced by 68.3% and 67.6% respectively.展开更多
Dual-color(blue and green) InGaN/GaN nanorod light-emitting diodes(LEDs) with three different nanorod diameters are fabricated. Enhancement of luminescence intensity per area is observed in blue and green wells,to var...Dual-color(blue and green) InGaN/GaN nanorod light-emitting diodes(LEDs) with three different nanorod diameters are fabricated. Enhancement of luminescence intensity per area is observed in blue and green wells,to varying degrees. When the diameter is 40 nm, it sharply decreases, which could be explained by the sidewall nonradiative recombination. Time-resolved photoluminescence is conducted to study the carrier lifetime. High recombination rate is observed in nanorod arrays, and is an order of magnitude less than that of the planar LED.When the diameter is 40 nm, the nonradiative lifetime decreases, and this explains the decrease of intensity. The3 D-FDTD simulations show the enhancement of light extraction out of geometry structure by calculating the transmittance of the nanorod arrays.展开更多
Vectored non-covalent interactions—mainly hydrogen bonding and aromatic interactions—extensively contribute to(bio)-organic self-assembling processes and significantly impact the physicochemical properties of the as...Vectored non-covalent interactions—mainly hydrogen bonding and aromatic interactions—extensively contribute to(bio)-organic self-assembling processes and significantly impact the physicochemical properties of the associated superstructures.However,vectored non-covalent interaction-driven assembly occursmainly along one-dimensional(1D)or three-dimensional(3D)directions,and a two-dimensional(2D)orientation,especially that of multilayered,graphene-like assembly,has been reported less.In this present research,by introducing amino,hydroxyl,and phenyl moieties to the triazine skeleton,supramolecular layered assembly is achieved by vectored non-covalent interactions.The planar hydrogen bonding network results in high stability,with a thermal sustainability of up to about 330°C and a Young’s modulus of up to about 40 GPa.Upon introducing wrinkles by biased hydrogen bonding or aromatic interactions to disturb the planar organization,the stability attenuates.However,the intertwined aromatic interactions prompt a red edge excitation shift effect inside the assemblies,inducing broad-spectrum fluorescence covering nearly the entire visible light region(400–650 nm).We show that bionic,superhydrophobic,pillar-like arrays with contact angles of up to about 170°can be engineered by aromatic interactions using a physical vapor deposition approach,which cannot be realized through hydrogen bonding.Our findings show the feasibility of 2D assembly with engineerable properties by modulating vectored non-covalent interactions.展开更多
The Chang＇e-3 panoramic camera, which is composed of two cameras with identical functions, performances and interfaces, is installed on the lunar rover mast. It can acquire 3D images of the lunar surface based on the...The Chang＇e-3 panoramic camera, which is composed of two cameras with identical functions, performances and interfaces, is installed on the lunar rover mast. It can acquire 3D images of the lunar surface based on the principle of binocular stereo vision. By rotating and pitching the mast, it can take several photographs of the patrol area. After stitching these images, panoramic images of the scenes will be obtained.Thus the topography and geomorphology of the patrol area and the impact crater, as well as the geological structure of the lunar surface, will be analyzed and studied.In addition, it can take color photographs of the lander using the Bayer color coding principle. It can observe the working status of the lander by switching between static image mode and dynamic video mode with automatic exposure time. The focal length of the lens on the panoramic camera is 50 mm and the field of view is 19.7？umination and viewing conditions, the largest signal-to-no×14.5？.Under the best illise ratio of the panoramic camera is 44 d B. Its static modulation transfer function is 0.33. A large number of ground testing experiments and on-orbit imaging results show that the functional interface of the panoramic camera works normally. The image quality of the panoramic camera is satisfactory. All the performance parameters of the panoramic camera satisfy the design requirements.展开更多
The middle and lower reaches of the Yangtze River,a primary region for freshwater lakes in China,have undergone significant transformations throughout the Holocene.These changes,driven by factors such as sea-level ris...The middle and lower reaches of the Yangtze River,a primary region for freshwater lakes in China,have undergone significant transformations throughout the Holocene.These changes,driven by factors such as sea-level rise,climate change,and human activities,have led to the progressive elevation of water levels in this area.As a result,a floodplain has emerged,characterized by the formation of numerous shallow lakes along the river course.However,the pattern of water-level changes in the main channel of the Yangtze River during the Holocene remains unclear.This gap in knowledge poses challenges for understanding sediment transport dynamics,the interactions between the river and its adjacent lakes,and the prevention and control of flood disasters in the Yangtze River basin.To shed light on these issues,our study compiled data on the surface elevation and water depth of 81 lakes in the mid-lower reaches of the Yangtze River basin.Additionally,we analyzed historical water-level records from the 1900s to the 1970s at eight gauging stations from Shashi to Jiangyin along the river’s main stream.Our findings reveal that,particularly along the Jingjiang section,the basal elevation of most lakes is lower than the Yangtze River’s water level during the dry season.Conversely,the water level of the main stream exceeds that of both the floodplain and the lakes enclosed by the Jingjiang embankment.In the tidal reach,especially within the Taihu Lake basin,the basal elevation of lakes typically falls below sea level.Meanwhile,lakes located along the section from Chenglingji to Wuhu exhibit basal elevations that correspond with the Yangtze River’s annual average and dry season water levels.Given the widespread presence of lakes along the middle and lower reaches of the Yangtze River,our study introduces a new proxy for reconstructing the mean water level of the mid-lower Yangtze River in the Holocene.By analyzing sediments from Nanyi Lake and Chenyao Lake in the lower Yangtze River,we attempted to reconstruct the water level of the Yangtze River’s main channel since 8 ka BP.展开更多
Photothermal catalytic oxidation emerges as a promising method for the removal of volatile organic compounds(VOCs).Herein,via sol-gel impregnation method,spinel CuMn_(2)O_(4)was coated on attapulgite honeycombs with i...Photothermal catalytic oxidation emerges as a promising method for the removal of volatile organic compounds(VOCs).Herein,via sol-gel impregnation method,spinel CuMn_(2)O_(4)was coated on attapulgite honeycombs with integrating biochar(BC)film as the second carrier,using chestnut shell as complexation agent.Various mass ratios of CuMn_(2)O_(4)to chestnut shell was modulated to investigate the catalytic toluene degradation performance.Results indicated that the monolithic CuMn_(2)O_(4)/BC/honeycomb catalyst demonstrated superior photothermal catalytic toluene degradation with a low T90(temperature at 90%degradation)of 263℃ when the mass ratio of CuMn_(2)O_(4)to biomass was 1:4.The addition of BC film substantially increased the honeycomb's specific surface area and improved the photothermal conversion of spinel,leading to enhanced photothermal catalytic activity.This study presents a cost-effective strategy for eliminating industrial VOCs using clay-biomass based monolithic catalyst.展开更多
Hydrogen bonds are non-covalent interactions and essential for assembling supermolecules into ordered structures in biological systems,endowing crystals with fascinating physical properties,and inspiring the construct...Hydrogen bonds are non-covalent interactions and essential for assembling supermolecules into ordered structures in biological systems,endowing crystals with fascinating physical properties,and inspiring the construction of eco-friendly electromechanical devices.However,the interplay between hydrogen bonding and the physical properties is not fully understood at the molecular level.Herein,we demonstrate that the physical property of biological crystals with double-layer structures could be enhanced by rationally controlling hydrogen bonding interactions between amino and carboxyl groups.Different hydrogen bonding interactions result in various thermal,mechanical,electronic,and piezoelectric properties.In particular,the weak interaction between O and H atoms contributes to low mechanical strength that permits important ion displacement under stress,giving rise to a strong piezoelectric response.This study not only reveals the correlation between the hydrogen bonding and physical properties in double-layer structures of biological crystals but also demonstrates the potential of these crystals as functional biomaterials for high-performance energy-harvesting devices.Theoretical calculations and experimental verifications in this work provide new insights into the rational design of biomaterials with desirable physical properties for bioelectrical devices by modulating intermolecular interactions.展开更多
Chinese lake status database has provided systematic geological records of much higher lake level and fresher water than today at the LGM from western China. This wet condition was significant contrast with very dry c...Chinese lake status database has provided systematic geological records of much higher lake level and fresher water than today at the LGM from western China. This wet condition was significant contrast with very dry conditions in eastern China. Together with lake studies from Eurasian continents, there was a wet-condition belt from the Mediterranean and the Middle East, Central Asia to western China. Palaeoclimate simulations confirmed that the wet conditions in western China were produced by decrease of the evaporation and increase of precipitation by positive anomaly of annual P-E of 70-95 mm/a between the LGM and today. The westerlies enhanced in the strength and shifted southwards-eastwards in the position, and the low thermal conditions in the Eurasian continent creating temperature 4-16℃ lower than today and relatively low evaporation, were the major two important climate conditions to yield cold-wet climates in western China.展开更多
Synthetic hydrogels are widely used as biomimetic in vitro model systems to understand how cells respond to complex microenvironments. The mechanical properties of hydrogels are deterministic for many cellular behavio...Synthetic hydrogels are widely used as biomimetic in vitro model systems to understand how cells respond to complex microenvironments. The mechanical properties of hydrogels are deterministic for many cellular behaviors, including cell migration, spreading, and differentiation. However, it remains a major challenge to engineer hydrogels that recapture the dynamic mechanical properties of native extracellular matrices. Here, we provide a new hydrogel platform with spatiotemporally tunable mechanical properties to assay and define cellular behaviors under light. The change in the mechanical properties of the hydrogel is effected by a photo-induced switch of the cross-linker fluorescent protein, Dronpa145N, between the tetrameric and monomeric states, which causes minimal changes to the chemical properties of the hydrogel. The mechanical properties can be rapidly and reversibly tuned for multiple cycles using visible light, as confirmed by rheological measurements and atomic force microscopy- based nano-indentation. We further demonstrated real-time and reversible modulation of cell migration behaviors on the hydrogels through photo-induced stiffness switching, with minimal invasion to the cultured cells. Hydrogels with a programmable mechanical history and a spatially defined mechanical hierarchy might serve as an ideal model system to better understand complex cellular functions.展开更多
Most aquatic ecosystems contribute elevated N2 O to atmosphere due to increasing anthropogenic nitrogen loading. To further understand the spatial heterogeneity along an aquatic continuum from the upriver to wetland t...Most aquatic ecosystems contribute elevated N2 O to atmosphere due to increasing anthropogenic nitrogen loading. To further understand the spatial heterogeneity along an aquatic continuum from the upriver to wetland to lake to downriver, the study was conducted on spatial variations in N2 O emission along Poyang Lake aquatic continuum during the flood season from 15 July 2013 to 10 August 2013. The results showed the N2 O concentrations, the ratio of N2O/dinitrogen（N2） gases production, N2 O emission and denitrification rates ranged from 0.10 to 1.11 μg N/L,- 0.007% to 0.051%,- 9.73 to 127 μg N/m2/hr and 1.33 × 104to31.9 × 104μg N2/m2/hr, respectively, across the continuum. The average N2 O concentrations,the ratio of N2O/N2 and N2O emission was significantly lower in wetlands as compared to the rivers and lake（p 〈 0.01）. The significantly high denitrification rate and low N2 O emission together highlighted that most N2 O can be converted into N2 via near complete denitrification in the Poyang Lake wetlands. Our study suggests that the wetlands might impact N2 O budget in an integrated aquatic ecosystems. Moreover, N2 O emission from different aquatic ecosystem should be considered separately when quantifying the regional budget in aquatic ecosystem.展开更多
Main observation and conclusion Polymer-supramolecular double-network hydrogels(PS-DN hydrogels)often show much improved recovery rates than conventional double-network hydrogels because of the fast self-assembling pr...Main observation and conclusion Polymer-supramolecular double-network hydrogels(PS-DN hydrogels)often show much improved recovery rates than conventional double-network hydrogels because of the fast self-assembling properties,making them attractive candidates for tissue engineering and flexible electronics.However,as the supramolecular network is dynamic and susceptible to break under low strains,the overall mechanical properties of PS-DN hydrogels are still limited.Here,we report the mechanical properties for PS-DN hydrogels can be significantly improved by tuning the supramolecular network structures.A single amino acid change of the self-assembling peptide can tune the assembled structures from nanofiber to nanoribbon.Such a microscopic structural change can greatly increase the Young's modulus(107.4 kPa),fracture stress(0.48 MPa),and toughness(0.38 MJ·m^(–3))of the PS-DN hydrogels.Moreover,the structural change also leads to slightly faster recovery rates(<1 s).We propose that such dramatically different mechanical properties can be understood by the impact of individual peptide rupture events on the overall network connectivity in the two scenarios.Our study may provide new inspirations for combining high mechanical strength and fast recovery in double network hydrogels by tuning the supramolecular network structures.展开更多
Positive type photosensitive polyimide is used as the modification layer in the thin film transistors production process. The photosensitive polyimide is not only used as the second insulating layer, it can also be us...Positive type photosensitive polyimide is used as the modification layer in the thin film transistors production process. The photosensitive polyimide is not only used as the second insulating layer, it can also be used instead of a mask because of the photosensitivity. A suitable curing condition can help photosensitive polyimide form the high performance polyimide with orderly texture inside, and the performance of imidization depends on the precise control of temperature, time, and heat control during the curing process. Therefore, experiments of different stepped up heating tests are made, and the ability of protecting silicon dioxide is analyzed.展开更多
Identifying local conformational changes induced by subtle differences on amino acid sequences is critical in exploring the functional variations of the proteins. In this study, we designed a computational scheme to p...Identifying local conformational changes induced by subtle differences on amino acid sequences is critical in exploring the functional variations of the proteins. In this study, we designed a computational scheme to predict the dihedral angle variations for different amino acid sequences by using conditional random field. This computational tool achieved an accuracy of 87% and 84% in 10-fold cross validation in a large data set for φ and ψ, respectively. The prediction accuracies of φand ψ are positively correlated to each other for most of the 20 types of amino acids. Helical amino acids can achieve higher prediction accuracy in general, while amino acids in beet sheet have higher accuracy at specific angular regions. The prediction accuracy of φ is negatively correlated with amino acid flexibility represented by Vihinen Index. The prediction accuracy of φ can also be negatively correlated with angle distribution dispersion.展开更多
基金supported by the National Natural Science Foundation of China(32271413 and 32271408)the National Basic Research Program of China(2021YFA1201404)+2 种基金the Natural Science Foundation of Jiangsu Province(BK20232023)the Science Program of Jiangsu Province Administration for Market Regulation(KJ2024010)the Jiangsu Provincial Key Medical Center Foundation,and the Jiangsu Provincial Medical Outstanding Talent Foundation.
文摘Hydrogel-based tissue-engineered skin has attracted increased attention due to its potential to restore the structural integrity and functionality of skin.However,the mechanical properties of hydrogel scaffolds and natural skin are substantially different.Here,we developed a polyvinyl alcohol(PVA)/acrylamide based interpenetrating network(IPN)hydrogel that was surface modified with polydopamine(PDA)and termed Dopa-gel.The Dopa-gel exhibited mechanical properties similar to native skin tissue and a superior ability to modulate paracrine functions.Furthermore,a tough scaffold with tensile resistance was fabricated using this hydrogel by three-dimensional printing.The results showed that the interpenetration of PVA,alginate,and polyacrylamide networks notably enhanced the mechanical properties of the hydrogel.Surface modification with PDA endowed the hydrogels with increased secretion of immunomodulatory and proangiogenic factors.In an in vivo model,Dopa-gel treatment accelerated wound closure,increased vascularization,and promoted a shift in macrophages from a proinflammatory M1 phenotype to a prohealing and anti-inflammatory M2 phenotype within the wound area.Mechanistically,the focal adhesion kinase(FAK)/extracellular signal-related kinase(ERK)signaling pathway may mediate the promotion of skin defect healing by increasing paracrine secretion via the Dopa-gel.Additionally,proangiogenic factors can be induced through Rho-associated kinase-2(ROCK-2)/vascular endothelial growth factor(VEGF)-mediated paracrine secretion under tensile stress conditions.Taken together,these findings suggest that the multifunctional Dopa-gel,which has good mechanical properties similar to those of native skin tissue and enhanced immunomodulatory and angiogenic properties,is a promising scaffold for skin tissue regeneration.
基金the Strategic Priority Research Program on Space Science of the Chinese Academy of Sciences,the grant No.XDA15320104,with additional contributions from the Purple Mountain Observatory(PMO)of the Chinese Academy of Sciences and the National Space Science Center(NSSC).
文摘For the ASO-S/HXI payload, the accuracy of the flare reconstruction is reliant on important factors such as the alignment of the dual grating and the precise measurement of observation orientation. To guarantee optimal functionality of the instrument throughout its life cycle, the Solar Aspect System (SAS) is imperative to ensure that measurements are accurate and reliable. This is achieved by capturing the target motion and utilizing a physical model-based inversion algorithm. However, the SAS optical system’s inversion model is a typical ill-posed inverse problem due to its optical parameters, which results in small target sampling errors triggering unacceptable shifts in the solution. To enhance inversion accuracy and make it more robust against observation errors, we suggest dividing the inversion operation into two stages based on the SAS spot motion model. First, the as-rigid-aspossible (ARAP) transformation algorithm calculates the relative rotations and an intermediate variable between the substrates. Second, we solve an inversion linear equation for the relative translation of the substrates, the offset of the optical axes, and the observation orientation. To address the ill-posed challenge, the Tikhonov method grounded on the discrepancy criterion and the maximum a posteriori (MAP) method founded on the Bayesian framework are utilized. The simulation results exhibit that the ARAP method achieves a solution with a rotational error of roughly±3 5 (1/2-quantile);both regularization techniques are successful in enhancing the stability of the solution, the variance of error in the MAP method is even smaller—it achieves a translational error of approximately±18μm (1/2-quantile) in comparison to the Tikhonov method’s error of around±24μm (1/2-quantile). Furthermore, the SAS practical application data indicates the method’s usability in this study. Lastly, this paper discusses the intrinsic interconnections between the regularization methods.
文摘The discovery of intrinsically disordered proteins （IDP） （i.e., biologically active proteins that do not possess stable secondary and/or tertiary structures） came as an unexpected surprise, as the existence of such proteins is in contradiction to the traditional ＂sequence →structure →function＂ paradigm. Accurate prediction of a protein＇s predisposition to be intrinsically disordered is a necessary prerequisite for the further understanding of principles and mechanisms of protein folding and function, and is a key for the elaboration of a new structural and functional hierarchy of proteins. Therefore, prediction of IDPs has attracted the attention of many researchers, and a number of prediction tools have been developed. Predictions of disorder, in turn, are playing major roles in directing laboratory experiments that are leading to the discovery of ever more disordered proteins, and thereby leading to a positive feedback loop in the investigation of these proteins. In this review of algorithms for intrinsic disorder prediction, the basic concepts of various prediction methods for IDPs are summarized, the strengths and shortcomings of many of the methods are analyzed, and the difficulties and directions of future development of IDP prediction techniques are discussed.
基金Supported by the National Natural Science Foundation of China
文摘The terrain camera （TCAM） and panoramic camera （PCAM） are two of the major scientific payloads installed on the lander and rover of the Chang＇e 3 mission re- spectively. They both use a Bayer color filter array covering CMOS sensor to capture color images of the Moon＇s surface. RGB values of the original images are related to these two kinds of cameras. There is an obvious color difference compared with human visual perception. This paper follows standards published by the International Commission on Illumination to establish a color correction model, designs the ground calibration experiment and obtains the color correction coefficient. The image qual- ity has been significantly improved and there is no obvious color difference in the corrected images. Ground experimental results show that： （1） Compared with uncor- rected images, the average color difference of TCAM is 4.30, which has been reduced by 62.1%. （2） The average color differences of the left and right cameras in PCAM are 4.14 and 4.16, which have been reduced by 68.3% and 67.6% respectively.
基金Supported by the National Natural Science Foundation of China under Grant Nos 61505197 and 61334009the National Science and Technology Major Project under Grant No 2017YFB0403803
文摘Dual-color(blue and green) InGaN/GaN nanorod light-emitting diodes(LEDs) with three different nanorod diameters are fabricated. Enhancement of luminescence intensity per area is observed in blue and green wells,to varying degrees. When the diameter is 40 nm, it sharply decreases, which could be explained by the sidewall nonradiative recombination. Time-resolved photoluminescence is conducted to study the carrier lifetime. High recombination rate is observed in nanorod arrays, and is an order of magnitude less than that of the planar LED.When the diameter is 40 nm, the nonradiative lifetime decreases, and this explains the decrease of intensity. The3 D-FDTD simulations show the enhancement of light extraction out of geometry structure by calculating the transmittance of the nanorod arrays.
基金supported by the Fund for Creative Research Groups of National Natural Science Foundation of China (No. 51821093)the National Natural Science Foundation of China (Nos. 52175551, 52075484)(KT and DM)+2 种基金the National Key Research and Development Program (SQ2021YFE010405)(KT)Science Foundation Ireland (SFI) through awards Nos. 15/CDA/3491and 12/RC/2275_P2 (DT)computing resources at the SFI/Higher Education Authority Irish Center for High-End Computing (ICHEC)(SG and DT)
文摘Vectored non-covalent interactions—mainly hydrogen bonding and aromatic interactions—extensively contribute to(bio)-organic self-assembling processes and significantly impact the physicochemical properties of the associated superstructures.However,vectored non-covalent interaction-driven assembly occursmainly along one-dimensional(1D)or three-dimensional(3D)directions,and a two-dimensional(2D)orientation,especially that of multilayered,graphene-like assembly,has been reported less.In this present research,by introducing amino,hydroxyl,and phenyl moieties to the triazine skeleton,supramolecular layered assembly is achieved by vectored non-covalent interactions.The planar hydrogen bonding network results in high stability,with a thermal sustainability of up to about 330°C and a Young’s modulus of up to about 40 GPa.Upon introducing wrinkles by biased hydrogen bonding or aromatic interactions to disturb the planar organization,the stability attenuates.However,the intertwined aromatic interactions prompt a red edge excitation shift effect inside the assemblies,inducing broad-spectrum fluorescence covering nearly the entire visible light region(400–650 nm).We show that bionic,superhydrophobic,pillar-like arrays with contact angles of up to about 170°can be engineered by aromatic interactions using a physical vapor deposition approach,which cannot be realized through hydrogen bonding.Our findings show the feasibility of 2D assembly with engineerable properties by modulating vectored non-covalent interactions.
文摘The Chang＇e-3 panoramic camera, which is composed of two cameras with identical functions, performances and interfaces, is installed on the lunar rover mast. It can acquire 3D images of the lunar surface based on the principle of binocular stereo vision. By rotating and pitching the mast, it can take several photographs of the patrol area. After stitching these images, panoramic images of the scenes will be obtained.Thus the topography and geomorphology of the patrol area and the impact crater, as well as the geological structure of the lunar surface, will be analyzed and studied.In addition, it can take color photographs of the lander using the Bayer color coding principle. It can observe the working status of the lander by switching between static image mode and dynamic video mode with automatic exposure time. The focal length of the lens on the panoramic camera is 50 mm and the field of view is 19.7？umination and viewing conditions, the largest signal-to-no×14.5？.Under the best illise ratio of the panoramic camera is 44 d B. Its static modulation transfer function is 0.33. A large number of ground testing experiments and on-orbit imaging results show that the functional interface of the panoramic camera works normally. The image quality of the panoramic camera is satisfactory. All the performance parameters of the panoramic camera satisfy the design requirements.
基金supported by the National Natural Science Foundation of China(Grant No.41972194)the Study on the Origin of Chinese Civilization in Jiangsu Province。
文摘The middle and lower reaches of the Yangtze River,a primary region for freshwater lakes in China,have undergone significant transformations throughout the Holocene.These changes,driven by factors such as sea-level rise,climate change,and human activities,have led to the progressive elevation of water levels in this area.As a result,a floodplain has emerged,characterized by the formation of numerous shallow lakes along the river course.However,the pattern of water-level changes in the main channel of the Yangtze River during the Holocene remains unclear.This gap in knowledge poses challenges for understanding sediment transport dynamics,the interactions between the river and its adjacent lakes,and the prevention and control of flood disasters in the Yangtze River basin.To shed light on these issues,our study compiled data on the surface elevation and water depth of 81 lakes in the mid-lower reaches of the Yangtze River basin.Additionally,we analyzed historical water-level records from the 1900s to the 1970s at eight gauging stations from Shashi to Jiangyin along the river’s main stream.Our findings reveal that,particularly along the Jingjiang section,the basal elevation of most lakes is lower than the Yangtze River’s water level during the dry season.Conversely,the water level of the main stream exceeds that of both the floodplain and the lakes enclosed by the Jingjiang embankment.In the tidal reach,especially within the Taihu Lake basin,the basal elevation of lakes typically falls below sea level.Meanwhile,lakes located along the section from Chenglingji to Wuhu exhibit basal elevations that correspond with the Yangtze River’s annual average and dry season water levels.Given the widespread presence of lakes along the middle and lower reaches of the Yangtze River,our study introduces a new proxy for reconstructing the mean water level of the mid-lower Yangtze River in the Holocene.By analyzing sediments from Nanyi Lake and Chenyao Lake in the lower Yangtze River,we attempted to reconstruct the water level of the Yangtze River’s main channel since 8 ka BP.
基金supported by the National Natural Science Foundation of China(Grant No.51674043)Jiangsu High Institutions Key Basic Research Projects of Natural Science(Grant No.21KJA430002)+2 种基金Changzhou International Cooperation Project(Grant No.CZ20230018)Foundation of Social Development of Changzhou(Grant No.CE20225063)International Joint Laboratory of the Jiangsu Education Department.
文摘Photothermal catalytic oxidation emerges as a promising method for the removal of volatile organic compounds(VOCs).Herein,via sol-gel impregnation method,spinel CuMn_(2)O_(4)was coated on attapulgite honeycombs with integrating biochar(BC)film as the second carrier,using chestnut shell as complexation agent.Various mass ratios of CuMn_(2)O_(4)to chestnut shell was modulated to investigate the catalytic toluene degradation performance.Results indicated that the monolithic CuMn_(2)O_(4)/BC/honeycomb catalyst demonstrated superior photothermal catalytic toluene degradation with a low T90(temperature at 90%degradation)of 263℃ when the mass ratio of CuMn_(2)O_(4)to biomass was 1:4.The addition of BC film substantially increased the honeycomb's specific surface area and improved the photothermal conversion of spinel,leading to enhanced photothermal catalytic activity.This study presents a cost-effective strategy for eliminating industrial VOCs using clay-biomass based monolithic catalyst.
基金the National Nature Science Foundation of China(grant nos.52192610,51973170,12002054,and 52202186)Ministry of Science and Technology of China(grant no.SQ2021YFE010405)+7 种基金Israel Science Foundation and National Natural Sciences Foundation of China Bilateral grant(grant no.3145/19)Ministry of Science and Technology of Israel project(grant no.3-18130)the China-Israel Cooperative Scientific Research,Fundamental Research Funds for the Central Universities(grant no.ZDRC2205)Fundamental Research Funds for the Central Universities(grant no.JC2107)Natural Science Foundation of Shaanxi Province(grant nos.2019JCW-17 and 2020JCW-15)Development and Planning Guide Foundation of Xidian University(grant no.21103200005)Fundamental Research Funds for the Central Universities(grant no.JC2107)State Scholarship Fund of China Scholarship Council(grant no.202006960032).
文摘Hydrogen bonds are non-covalent interactions and essential for assembling supermolecules into ordered structures in biological systems,endowing crystals with fascinating physical properties,and inspiring the construction of eco-friendly electromechanical devices.However,the interplay between hydrogen bonding and the physical properties is not fully understood at the molecular level.Herein,we demonstrate that the physical property of biological crystals with double-layer structures could be enhanced by rationally controlling hydrogen bonding interactions between amino and carboxyl groups.Different hydrogen bonding interactions result in various thermal,mechanical,electronic,and piezoelectric properties.In particular,the weak interaction between O and H atoms contributes to low mechanical strength that permits important ion displacement under stress,giving rise to a strong piezoelectric response.This study not only reveals the correlation between the hydrogen bonding and physical properties in double-layer structures of biological crystals but also demonstrates the potential of these crystals as functional biomaterials for high-performance energy-harvesting devices.Theoretical calculations and experimental verifications in this work provide new insights into the rational design of biomaterials with desirable physical properties for bioelectrical devices by modulating intermolecular interactions.
文摘Chinese lake status database has provided systematic geological records of much higher lake level and fresher water than today at the LGM from western China. This wet condition was significant contrast with very dry conditions in eastern China. Together with lake studies from Eurasian continents, there was a wet-condition belt from the Mediterranean and the Middle East, Central Asia to western China. Palaeoclimate simulations confirmed that the wet conditions in western China were produced by decrease of the evaporation and increase of precipitation by positive anomaly of annual P-E of 70-95 mm/a between the LGM and today. The westerlies enhanced in the strength and shifted southwards-eastwards in the position, and the low thermal conditions in the Eurasian continent creating temperature 4-16℃ lower than today and relatively low evaporation, were the major two important climate conditions to yield cold-wet climates in western China.
基金We thank Dr. W. Meng for his initial experiments on this project. This work is funded by the National Natural Science Foundation of China （Nos. 21522402, 21474003, 91427304, 11372279, 11572285, 11674153,11374148, and 11334004）, the Fundamental Research Funds for the Central Universities （Nos. 020414380070 and 020414380058）, the National Basic Research Program of China （Nos. 2012CB921801 and 2013CB834100） and the National High-tech R＆D Program of China （No. 2015AA020941）.
文摘Synthetic hydrogels are widely used as biomimetic in vitro model systems to understand how cells respond to complex microenvironments. The mechanical properties of hydrogels are deterministic for many cellular behaviors, including cell migration, spreading, and differentiation. However, it remains a major challenge to engineer hydrogels that recapture the dynamic mechanical properties of native extracellular matrices. Here, we provide a new hydrogel platform with spatiotemporally tunable mechanical properties to assay and define cellular behaviors under light. The change in the mechanical properties of the hydrogel is effected by a photo-induced switch of the cross-linker fluorescent protein, Dronpa145N, between the tetrameric and monomeric states, which causes minimal changes to the chemical properties of the hydrogel. The mechanical properties can be rapidly and reversibly tuned for multiple cycles using visible light, as confirmed by rheological measurements and atomic force microscopy- based nano-indentation. We further demonstrated real-time and reversible modulation of cell migration behaviors on the hydrogels through photo-induced stiffness switching, with minimal invasion to the cultured cells. Hydrogels with a programmable mechanical history and a spatially defined mechanical hierarchy might serve as an ideal model system to better understand complex cellular functions.
基金supported by the Research Program of State Key Laboratory of Lake Science and Environment(No.2012SKL012)CAS Key Project(No.KJZD-EW-TZ-G10)+1 种基金the National Basic Research Program(973)of China(No.2012CB417005)the Poyang Lake Wetland Integrated Research Station for their help on field study
文摘Most aquatic ecosystems contribute elevated N2 O to atmosphere due to increasing anthropogenic nitrogen loading. To further understand the spatial heterogeneity along an aquatic continuum from the upriver to wetland to lake to downriver, the study was conducted on spatial variations in N2 O emission along Poyang Lake aquatic continuum during the flood season from 15 July 2013 to 10 August 2013. The results showed the N2 O concentrations, the ratio of N2O/dinitrogen（N2） gases production, N2 O emission and denitrification rates ranged from 0.10 to 1.11 μg N/L,- 0.007% to 0.051%,- 9.73 to 127 μg N/m2/hr and 1.33 × 104to31.9 × 104μg N2/m2/hr, respectively, across the continuum. The average N2 O concentrations,the ratio of N2O/N2 and N2O emission was significantly lower in wetlands as compared to the rivers and lake（p 〈 0.01）. The significantly high denitrification rate and low N2 O emission together highlighted that most N2 O can be converted into N2 via near complete denitrification in the Poyang Lake wetlands. Our study suggests that the wetlands might impact N2 O budget in an integrated aquatic ecosystems. Moreover, N2 O emission from different aquatic ecosystem should be considered separately when quantifying the regional budget in aquatic ecosystem.
基金supported mainly by the National Natural Science Foundation of China(Nos.11804148,11804147,11674153 and 12002149)the Natural Science Foundation of Jiangsu Province(Nos.BK20180320 and BK20180335)+1 种基金the Fundamental Research Funds for the Central Universities(Nos.020414380187,020414380148 and 020414380138)the Technological Innovation Foundation of Nanjing University(No.020414913413).
文摘Main observation and conclusion Polymer-supramolecular double-network hydrogels(PS-DN hydrogels)often show much improved recovery rates than conventional double-network hydrogels because of the fast self-assembling properties,making them attractive candidates for tissue engineering and flexible electronics.However,as the supramolecular network is dynamic and susceptible to break under low strains,the overall mechanical properties of PS-DN hydrogels are still limited.Here,we report the mechanical properties for PS-DN hydrogels can be significantly improved by tuning the supramolecular network structures.A single amino acid change of the self-assembling peptide can tune the assembled structures from nanofiber to nanoribbon.Such a microscopic structural change can greatly increase the Young's modulus(107.4 kPa),fracture stress(0.48 MPa),and toughness(0.38 MJ·m^(–3))of the PS-DN hydrogels.Moreover,the structural change also leads to slightly faster recovery rates(<1 s).We propose that such dramatically different mechanical properties can be understood by the impact of individual peptide rupture events on the overall network connectivity in the two scenarios.Our study may provide new inspirations for combining high mechanical strength and fast recovery in double network hydrogels by tuning the supramolecular network structures.
文摘Positive type photosensitive polyimide is used as the modification layer in the thin film transistors production process. The photosensitive polyimide is not only used as the second insulating layer, it can also be used instead of a mask because of the photosensitivity. A suitable curing condition can help photosensitive polyimide form the high performance polyimide with orderly texture inside, and the performance of imidization depends on the precise control of temperature, time, and heat control during the curing process. Therefore, experiments of different stepped up heating tests are made, and the ability of protecting silicon dioxide is analyzed.
文摘Identifying local conformational changes induced by subtle differences on amino acid sequences is critical in exploring the functional variations of the proteins. In this study, we designed a computational scheme to predict the dihedral angle variations for different amino acid sequences by using conditional random field. This computational tool achieved an accuracy of 87% and 84% in 10-fold cross validation in a large data set for φ and ψ, respectively. The prediction accuracies of φand ψ are positively correlated to each other for most of the 20 types of amino acids. Helical amino acids can achieve higher prediction accuracy in general, while amino acids in beet sheet have higher accuracy at specific angular regions. The prediction accuracy of φ is negatively correlated with amino acid flexibility represented by Vihinen Index. The prediction accuracy of φ can also be negatively correlated with angle distribution dispersion.
