In response to the national strategy of“vigorously cultivating interdisciplinary talents and actively promoting interdisciplinary integration,”this article focuses on the nationally recognized Environmental Design p...In response to the national strategy of“vigorously cultivating interdisciplinary talents and actively promoting interdisciplinary integration,”this article focuses on the nationally recognized Environmental Design program at Hezhou University’s College of Design,leveraging local industry advantages to engage in interdisciplinary integration through educational practices.Using the“Construction of the Panoramic Virtual Nature Museum of the Guizhou Crocodile Lizard at Mount Dagui”as a case study,we aim to establish a professional and interdisciplinary learning community,incorporate student-centered interactive teaching methods,boost student motivation,enhance teaching quality,nurture forward-thinking versatile innovative talents,and provide a guideline for interdisciplinary educational reform.展开更多
Moutan Cortex (MC) has been demonstrated to have an inhibitive effect on inflammation and oxidative stress responses in mesangial cells in our previous study. However, little is known about the components of MC contri...Moutan Cortex (MC) has been demonstrated to have an inhibitive effect on inflammation and oxidative stress responses in mesangial cells in our previous study. However, little is known about the components of MC contributing to this benefit. In the present study, cell membrane immobilized chromatography (CMC), a fast and useful method, was presented for screening potential active components of MC. HBZY-1 cells were incubated with MC (200 μg/mL) at the optimal incubation time (90 min). HPLC-DAD analysis and LC/ESI/MS/MS were performed to distinguish the active components and identify its structural ion fragments. The results showed that eight components binding to HBZY-1 cells were mudanoside B, paeoniflorin sulfonate, paeoniflorin, tetragalloyl glucose (isomeride), hexagalloyl glucose, mudanopiside A, and paeonol. In conclusion, our established CMC might be a useful method for screening potential active components in complicated traditional Chinese medicines. These components might be associated with the efficacy of MC on prevention and treatment of diabetic nephropathy.展开更多
In this contribution, we reported a novel approach to crosslink poly(ε-caprolactone)(PCL) via supramolecular hydrogen bonding interactions. First, a series of octa-armed poly(ε-caprolactone) stars with polyhedral ol...In this contribution, we reported a novel approach to crosslink poly(ε-caprolactone)(PCL) via supramolecular hydrogen bonding interactions. First, a series of octa-armed poly(ε-caprolactone) stars with polyhedral oligomeric silsesquioxane(POSS) cores were synthesized via the ring-opening polymerizations. Thereafter, the arm ends of organic-inorganic star-shaped PCLs were reacted with 2-(6-isocyanatohexylaminocarbonylamino)-6-methyl-4[1 H]-pyrimidinone to obtain 2-ureido-4[1 H]-pyrimidone(UPy)-terminated PCL stars.Notably, the UPy-terminated PCL stars were physically crosslinked, which was evidenced by means of dynamic mechanical thermal analysis(DMTA) and rheological analysis. Owing to the formation of the physically-crosslinked networks, the organic-inorganic PCL stars displayed significant shape memory properties with about 100% of shape recovery, which was in marked contrast to the PCL stars without UPy termini.展开更多
In this contribution, we reported a novel synthesis of block copolymer networks composed of poly(ε-caprolactone)(PCL) and polyethylene(PE) via the co-hydrolysis and condensation of α,ω-ditriethoxylsilane-terminated...In this contribution, we reported a novel synthesis of block copolymer networks composed of poly(ε-caprolactone)(PCL) and polyethylene(PE) via the co-hydrolysis and condensation of α,ω-ditriethoxylsilane-terminated PCL and PE telechelics. First, α,ω-dihydroxylterminated PCL and PE telechelics were synthesized via the ring-opening polymerization of ε-caprolactone and the ring-opening metathesis polymerization of cyclooctene followed by hydrogenation of polycyclooctene. Both α,ω-ditriethoxylsilane-terminated PCL and PE telechelics were obtained via in situ reaction of α,ω-dihydroxyl-terminated PCL and PE telechelics with 3-isocyanatopropyltriethoxysilane. The formation of networks was evidenced by the solubility and rheological tests. It was found that the block copolymer networks were microphase-separated. The PCL and PE blocks still preserved the crystallinity. Owing to the formation of crosslinked networks, the materials displayed shape memory properties. More importantly, the combination of PCL with PE resulted that the block copolymer networks had the triple shape memory properties, which can be triggered with the melting and crystallization of PCL and PE blocks. The results reported in this work demonstrated that triple shape memory polymers could be prepared via the formation of block copolymer networks.展开更多
In this contribution,we reported the preparation of vitrimers by using commodity thermoplastics via post crosslinking with hindered urea bonds(HUBs).First,three hindered urea diisocyanates(HUDIs)were synthesized via t...In this contribution,we reported the preparation of vitrimers by using commodity thermoplastics via post crosslinking with hindered urea bonds(HUBs).First,three hindered urea diisocyanates(HUDIs)were synthesized via the reactions of N,N'-di-tert-butylethylenediamine,N,N'-diethylethylenediamine,and piperazine with isophorone diisocyanate(IPDI).Thereafter,these HUDIs were used as the crosslinking agents to crosslink poly(hydroxyether of bisphenol A)(PH),a commodity thermoplastics.Fourier transform infrared(FTIR)spectroscopy and dynamic mechanical thermal analyses(DMTA)indicated that the PH thermosets were successfully obtained.It was found that the thermosets displayed the behavior of vitrimers.The PH thermosets can be reprocessed at elevated temperature without using catalyst and the mechanical strengths of vitrimers were recovered as high as 95%.The reprocessing properties are attributable to dynamic exchange reaction of hindered urea bonds,contingent on types of hindered urea bonds.展开更多
基金Research on the Construction and Interaction Design of the Mobile Panoramic Virtual Daguishan Alligator Lizard Natural Ecological Museum(2023HUKY01)Teaching Environmental Design Under the Background of Interdisciplinary Integration Study on the Reform of Learning Model(hzxyzcjg202301)The Curriculum Reform of Design Major Under the New Liberal Arts Perspective:A Study on the Path of Revolution and the Mode of Innovation Based on Guangxi Huang Gold Jewelry Design Industry College as a Perspective(hzxyzdjg202305)。
文摘In response to the national strategy of“vigorously cultivating interdisciplinary talents and actively promoting interdisciplinary integration,”this article focuses on the nationally recognized Environmental Design program at Hezhou University’s College of Design,leveraging local industry advantages to engage in interdisciplinary integration through educational practices.Using the“Construction of the Panoramic Virtual Nature Museum of the Guizhou Crocodile Lizard at Mount Dagui”as a case study,we aim to establish a professional and interdisciplinary learning community,incorporate student-centered interactive teaching methods,boost student motivation,enhance teaching quality,nurture forward-thinking versatile innovative talents,and provide a guideline for interdisciplinary educational reform.
文摘Moutan Cortex (MC) has been demonstrated to have an inhibitive effect on inflammation and oxidative stress responses in mesangial cells in our previous study. However, little is known about the components of MC contributing to this benefit. In the present study, cell membrane immobilized chromatography (CMC), a fast and useful method, was presented for screening potential active components of MC. HBZY-1 cells were incubated with MC (200 μg/mL) at the optimal incubation time (90 min). HPLC-DAD analysis and LC/ESI/MS/MS were performed to distinguish the active components and identify its structural ion fragments. The results showed that eight components binding to HBZY-1 cells were mudanoside B, paeoniflorin sulfonate, paeoniflorin, tetragalloyl glucose (isomeride), hexagalloyl glucose, mudanopiside A, and paeonol. In conclusion, our established CMC might be a useful method for screening potential active components in complicated traditional Chinese medicines. These components might be associated with the efficacy of MC on prevention and treatment of diabetic nephropathy.
基金financially supported by the National Natural Science Foundation of China(Nos.51133003,21274091,and21774078)
文摘In this contribution, we reported a novel approach to crosslink poly(ε-caprolactone)(PCL) via supramolecular hydrogen bonding interactions. First, a series of octa-armed poly(ε-caprolactone) stars with polyhedral oligomeric silsesquioxane(POSS) cores were synthesized via the ring-opening polymerizations. Thereafter, the arm ends of organic-inorganic star-shaped PCLs were reacted with 2-(6-isocyanatohexylaminocarbonylamino)-6-methyl-4[1 H]-pyrimidinone to obtain 2-ureido-4[1 H]-pyrimidone(UPy)-terminated PCL stars.Notably, the UPy-terminated PCL stars were physically crosslinked, which was evidenced by means of dynamic mechanical thermal analysis(DMTA) and rheological analysis. Owing to the formation of the physically-crosslinked networks, the organic-inorganic PCL stars displayed significant shape memory properties with about 100% of shape recovery, which was in marked contrast to the PCL stars without UPy termini.
基金the National Natural Science Foundation of China for the financial supports of this work(Nos.51973113,51133003 and 21774078)。
文摘In this contribution, we reported a novel synthesis of block copolymer networks composed of poly(ε-caprolactone)(PCL) and polyethylene(PE) via the co-hydrolysis and condensation of α,ω-ditriethoxylsilane-terminated PCL and PE telechelics. First, α,ω-dihydroxylterminated PCL and PE telechelics were synthesized via the ring-opening polymerization of ε-caprolactone and the ring-opening metathesis polymerization of cyclooctene followed by hydrogenation of polycyclooctene. Both α,ω-ditriethoxylsilane-terminated PCL and PE telechelics were obtained via in situ reaction of α,ω-dihydroxyl-terminated PCL and PE telechelics with 3-isocyanatopropyltriethoxysilane. The formation of networks was evidenced by the solubility and rheological tests. It was found that the block copolymer networks were microphase-separated. The PCL and PE blocks still preserved the crystallinity. Owing to the formation of crosslinked networks, the materials displayed shape memory properties. More importantly, the combination of PCL with PE resulted that the block copolymer networks had the triple shape memory properties, which can be triggered with the melting and crystallization of PCL and PE blocks. The results reported in this work demonstrated that triple shape memory polymers could be prepared via the formation of block copolymer networks.
基金the National Natural Science Foundation of China(Nos.51973113,51133003,and 21774078).
文摘In this contribution,we reported the preparation of vitrimers by using commodity thermoplastics via post crosslinking with hindered urea bonds(HUBs).First,three hindered urea diisocyanates(HUDIs)were synthesized via the reactions of N,N'-di-tert-butylethylenediamine,N,N'-diethylethylenediamine,and piperazine with isophorone diisocyanate(IPDI).Thereafter,these HUDIs were used as the crosslinking agents to crosslink poly(hydroxyether of bisphenol A)(PH),a commodity thermoplastics.Fourier transform infrared(FTIR)spectroscopy and dynamic mechanical thermal analyses(DMTA)indicated that the PH thermosets were successfully obtained.It was found that the thermosets displayed the behavior of vitrimers.The PH thermosets can be reprocessed at elevated temperature without using catalyst and the mechanical strengths of vitrimers were recovered as high as 95%.The reprocessing properties are attributable to dynamic exchange reaction of hindered urea bonds,contingent on types of hindered urea bonds.
