Liver cancer,one of the most common malignancies worldwide,ranks sixth in incidence and third in mortality.Liver cancer treatment options are diverse,inclu-ding surgical resection,liver transplantation,percutaneous ab...Liver cancer,one of the most common malignancies worldwide,ranks sixth in incidence and third in mortality.Liver cancer treatment options are diverse,inclu-ding surgical resection,liver transplantation,percutaneous ablation,transarterial chemoembolization,radiotherapy,chemotherapy,targeted therapy,immuno-therapy,and traditional Chinese medicine(TCM).A multidisciplinary team(MDT)is essential to customize treatment plans based on tumor staging,liver function,and performance status(PS),ensuring individualized patient care.Treatment decisions require a MDT to tailor strategies based on tumor staging,liver function,and PS,ensuring personalized care.The approval of new first-line and second-line drugs and the establishment of standard treatments based on immune checkpoint inhibitors have significantly expanded treatment options for advanced liver cancer,improving overall prognosis.However,many patients do not respond effectively to these treatments and ultimately succumb to the disease.Modern oncology treatments,while extending patient survival,often come with severe side effects,resistance,and damage to the body,negatively impacting quality of life.Huang et al's study published at World Journal of Gastroenterology rigorously validates the anticancer properties of Calculus bovis,enhancing our understanding of TCM and contributing to new liver cancer treatment strategies.For over 5000 years,TCM has been used in East Asian countries like China to treat various diseases,including liver conditions.Analysis of real-world clinical data suggests that for patients with advanced-stage tumors lacking effective treatments,integrated TCM therapies could provide significant breakthroughs.展开更多
BACKGROUND： Bone marrow mesenchymal stem cells （BMMSCs） exert immunosuppressive activities in transplantation. This study aimed to determine whether BMMSCs reduce acute re- jection and improve outcomes of liver tra...BACKGROUND： Bone marrow mesenchymal stem cells （BMMSCs） exert immunosuppressive activities in transplantation. This study aimed to determine whether BMMSCs reduce acute re- jection and improve outcomes of liver transDlantation in rats.展开更多
The two-component Camassa–Holm equation includes many intriguing phenomena. We propose a multi-symplectic compact method to solve the two-component Camassa–Holm equation. Based on its multi-symplectic formulation, t...The two-component Camassa–Holm equation includes many intriguing phenomena. We propose a multi-symplectic compact method to solve the two-component Camassa–Holm equation. Based on its multi-symplectic formulation, the proposed method is derived by the sixth-order compact finite difference method in spatial discretization and the symplectic implicit midpoint scheme in temporal discretization. Numerical experiments finely describe the velocity and density variables in the two-component integrable system and distinctly display the evolvement of the singular solutions. Moreover, the proposed method shows good conservative properties during long-time numerical simulation.展开更多
文摘Liver cancer,one of the most common malignancies worldwide,ranks sixth in incidence and third in mortality.Liver cancer treatment options are diverse,inclu-ding surgical resection,liver transplantation,percutaneous ablation,transarterial chemoembolization,radiotherapy,chemotherapy,targeted therapy,immuno-therapy,and traditional Chinese medicine(TCM).A multidisciplinary team(MDT)is essential to customize treatment plans based on tumor staging,liver function,and performance status(PS),ensuring individualized patient care.Treatment decisions require a MDT to tailor strategies based on tumor staging,liver function,and PS,ensuring personalized care.The approval of new first-line and second-line drugs and the establishment of standard treatments based on immune checkpoint inhibitors have significantly expanded treatment options for advanced liver cancer,improving overall prognosis.However,many patients do not respond effectively to these treatments and ultimately succumb to the disease.Modern oncology treatments,while extending patient survival,often come with severe side effects,resistance,and damage to the body,negatively impacting quality of life.Huang et al's study published at World Journal of Gastroenterology rigorously validates the anticancer properties of Calculus bovis,enhancing our understanding of TCM and contributing to new liver cancer treatment strategies.For over 5000 years,TCM has been used in East Asian countries like China to treat various diseases,including liver conditions.Analysis of real-world clinical data suggests that for patients with advanced-stage tumors lacking effective treatments,integrated TCM therapies could provide significant breakthroughs.
基金supported by grants from the National Natural Science Foundation of China(81270528 and 81441022)Natural Science Foundation of Tianjin+1 种基金China(08JCYBJC08400,11JCZDJC27800 and 12JCZDJC25200)the Technology Foundation of Health Bureau in Tianjin,China(2011KY11)
文摘BACKGROUND： Bone marrow mesenchymal stem cells （BMMSCs） exert immunosuppressive activities in transplantation. This study aimed to determine whether BMMSCs reduce acute re- jection and improve outcomes of liver transDlantation in rats.
基金Supported by the National Natural Science Foundation of China under Grant Nos 11571366 and 11501570the Open Foundation of State Key Laboratory of High Performance Computing of China+1 种基金the Research Fund of the National University of Defense Technology under Grant No JC15-02-02the Fund from HPCL
文摘The two-component Camassa–Holm equation includes many intriguing phenomena. We propose a multi-symplectic compact method to solve the two-component Camassa–Holm equation. Based on its multi-symplectic formulation, the proposed method is derived by the sixth-order compact finite difference method in spatial discretization and the symplectic implicit midpoint scheme in temporal discretization. Numerical experiments finely describe the velocity and density variables in the two-component integrable system and distinctly display the evolvement of the singular solutions. Moreover, the proposed method shows good conservative properties during long-time numerical simulation.
