OBJECTIVE: To investigate a quantitative method for using radial artery pulse waveforms to assess the effect of pulsatile flow during cardiopulmonary bypass(CPB).METHODS: A total of 34 adults with heart disease who un...OBJECTIVE: To investigate a quantitative method for using radial artery pulse waveforms to assess the effect of pulsatile flow during cardiopulmonary bypass(CPB).METHODS: A total of 34 adults with heart disease who underwent open-heart surgery between April2010 and January 2011 were randomized into a pulsatile perfusion group(n=17) and a non-pulsatile perfusion group(n=17). Radial arterial pulse waveforms of pulsatile and non-pulsatile perfusion patients were observed and compared before and during CPB.RESULTS: No pulse waveform could be detected at patients' radial artery in both groups when the aorta was cross-clamped. Pulse waveforms could be detected at pulsatile perfusion patients' radial artery, but could not be detected at non-pulsatile perfusion patients' radial artery during CPB. Additionally, patients' pulse waveforms during pulsatile perfusion were lower than those before the operation.CONCLUSION: Our findings indicate that radial artery sphygmogram can be used as a valid indicator to evaluate the effectiveness of pulsatile perfusion during CPB.展开更多
Closure or the presence of a ＂hole＂ is an emergent perceptual feature that can be extracted by the visual system early on. This feature has been shown to have perceptual advantages over openness or ＂no-hole＂. in t...Closure or the presence of a ＂hole＂ is an emergent perceptual feature that can be extracted by the visual system early on. This feature has been shown to have perceptual advantages over openness or ＂no-hole＂. in this study, we investigated when and how the human brain differentiates between ＂hole＂ and ＂no-hole＂ figures. Event-related potentials （ERPs） were recorded during a passive observation paradigm. Two pairs of simple figures （Experiment 1） and two sets of Greek letters （Experiment 2） were used as stimuli. The ERPs of ＂hole＂ and ＂no-hole＂ figures differed ~90 ms after stimulus onset： ＂hole＂ figures elicited smaller P1 and N1 amplitudes than ＂no-hole＂ figures. These suggest that both P1 and N1 components are sensitive to the difference between ＂hole＂ and ＂no-hole＂ figures; perception of ＂hole＂ and ＂no-hole＂ figures might be differentiated early during visual processing.展开更多
Cognitive functions are often studied using eventrelated potentials（ERPs）that are usually estimated by an averaging algorithm.Clearly,estimation of single-trial ERPs can provide researchers with many more details of...Cognitive functions are often studied using eventrelated potentials（ERPs）that are usually estimated by an averaging algorithm.Clearly,estimation of single-trial ERPs can provide researchers with many more details of cognitive activity than the averaging algorithm.A novel method to estimate single-trial ERPs is proposed in this paper.This method includes two key ideas.First,singular value decomposition was used to construct a matrix,which mapped singletrial electroencephalographic recordings（EEG）into a low-dimensional vector that contained little information from the spontaneous EEG.Second,we used the theory of compressed sensing to build a procedure to restore single-trial ERPs from this low-dimensional vector.ERPs are sparse or approximately sparse in the frequency domain.This fact allowed us to use the theory of compressed sensing.We verified this method in simulated and real data.Our method and dVCA（differentially variable component analysis）,another method of single-trial ERPs estimation,were both used to estimate single-trial ERPs from the same simulated data.Results demonstrated that our method significantly outperforms dVCA under various conditions of signal-to-noise ratio.Moreover,the single-trial ERPs estimated from the real data by our method are statistically consistent with the theories of cognitive science.展开更多
Chinese calligraphy,as a well-known performing art form,occupies an important role in the intangible cultural heritage of China.Previous studies focused on the psychophysiological benefits of Chinese calligraphy.Littl...Chinese calligraphy,as a well-known performing art form,occupies an important role in the intangible cultural heritage of China.Previous studies focused on the psychophysiological benefits of Chinese calligraphy.Little attention has been paid to its aesthetic attributes and effectiveness on the cognitive process.To complement our understanding of Chinese calligraphy,this study investigated the aesthetic experience of Chinese cursive-style calligraphy using brain functional network analysis.Subjects stayed on the coach and rested for several minutes.Then,they were requested to appreciate artwork of cursive-style calligraphy.Results showed that(1)changes in functional connectivity between frontooccipital,fronto-parietal,bilateral parietal,and central–occipital areas are prominent for calligraphy condition,(2)brain functional network showed an increased normalized cluster coefficient for calligraphy condition in alpha2 and gamma bands.These results demonstrate that the brain functional network undergoes a dynamic reconfiguration during the aesthetic experience of Chinese calligraphy.Providing evidence that the aesthetic experience of Chinese calligraphy has several similarities with western art while retaining its unique characters as an eastern traditional art form.展开更多
基金Grants from the National Natural Science Foundation of China(No.81173200,No.81373556)the Research and Assessment of the Effects of Pulsatile Perfusion During Cardiopulmonary Bypass Based on the Monitoring"Cunkou"Pulse Waveforms of Traditional Chinese Medicine Research Fund of Shanghai Municipal Public Health Bureau(No.2010J015A)
文摘OBJECTIVE: To investigate a quantitative method for using radial artery pulse waveforms to assess the effect of pulsatile flow during cardiopulmonary bypass(CPB).METHODS: A total of 34 adults with heart disease who underwent open-heart surgery between April2010 and January 2011 were randomized into a pulsatile perfusion group(n=17) and a non-pulsatile perfusion group(n=17). Radial arterial pulse waveforms of pulsatile and non-pulsatile perfusion patients were observed and compared before and during CPB.RESULTS: No pulse waveform could be detected at patients' radial artery in both groups when the aorta was cross-clamped. Pulse waveforms could be detected at pulsatile perfusion patients' radial artery, but could not be detected at non-pulsatile perfusion patients' radial artery during CPB. Additionally, patients' pulse waveforms during pulsatile perfusion were lower than those before the operation.CONCLUSION: Our findings indicate that radial artery sphygmogram can be used as a valid indicator to evaluate the effectiveness of pulsatile perfusion during CPB.
基金supported by the National Natural Science Foundation of China(61005087,61263042)Science and Technology Project of Yunnan Province,China(2009CD018)+2 种基金Key Science and Technology Project of Department of Education,Yunnan Province,China(2010Z067)Science and Technology Basic Research Fund of Yunnan University,China(KL080012,030-WX069051)the Major Program of National Social Science Foundation of China(11 & ZD187)
文摘Closure or the presence of a ＂hole＂ is an emergent perceptual feature that can be extracted by the visual system early on. This feature has been shown to have perceptual advantages over openness or ＂no-hole＂. in this study, we investigated when and how the human brain differentiates between ＂hole＂ and ＂no-hole＂ figures. Event-related potentials （ERPs） were recorded during a passive observation paradigm. Two pairs of simple figures （Experiment 1） and two sets of Greek letters （Experiment 2） were used as stimuli. The ERPs of ＂hole＂ and ＂no-hole＂ figures differed ~90 ms after stimulus onset： ＂hole＂ figures elicited smaller P1 and N1 amplitudes than ＂no-hole＂ figures. These suggest that both P1 and N1 components are sensitive to the difference between ＂hole＂ and ＂no-hole＂ figures; perception of ＂hole＂ and ＂no-hole＂ figures might be differentiated early during visual processing.
基金supported by National Basic Research Development Program (973 program) of China (2012CB825500,2011CB707800)National Natural Science Foundation of China (31271168)Natural Science Foundation of Fujian Province, China (2011J01344)
文摘Cognitive functions are often studied using eventrelated potentials（ERPs）that are usually estimated by an averaging algorithm.Clearly,estimation of single-trial ERPs can provide researchers with many more details of cognitive activity than the averaging algorithm.A novel method to estimate single-trial ERPs is proposed in this paper.This method includes two key ideas.First,singular value decomposition was used to construct a matrix,which mapped singletrial electroencephalographic recordings（EEG）into a low-dimensional vector that contained little information from the spontaneous EEG.Second,we used the theory of compressed sensing to build a procedure to restore single-trial ERPs from this low-dimensional vector.ERPs are sparse or approximately sparse in the frequency domain.This fact allowed us to use the theory of compressed sensing.We verified this method in simulated and real data.Our method and dVCA（differentially variable component analysis）,another method of single-trial ERPs estimation,were both used to estimate single-trial ERPs from the same simulated data.Results demonstrated that our method significantly outperforms dVCA under various conditions of signal-to-noise ratio.Moreover,the single-trial ERPs estimated from the real data by our method are statistically consistent with the theories of cognitive science.
基金the National Natural Science Foundation of China(Grant No.61772440,Grant No.62007016).
文摘Chinese calligraphy,as a well-known performing art form,occupies an important role in the intangible cultural heritage of China.Previous studies focused on the psychophysiological benefits of Chinese calligraphy.Little attention has been paid to its aesthetic attributes and effectiveness on the cognitive process.To complement our understanding of Chinese calligraphy,this study investigated the aesthetic experience of Chinese cursive-style calligraphy using brain functional network analysis.Subjects stayed on the coach and rested for several minutes.Then,they were requested to appreciate artwork of cursive-style calligraphy.Results showed that(1)changes in functional connectivity between frontooccipital,fronto-parietal,bilateral parietal,and central–occipital areas are prominent for calligraphy condition,(2)brain functional network showed an increased normalized cluster coefficient for calligraphy condition in alpha2 and gamma bands.These results demonstrate that the brain functional network undergoes a dynamic reconfiguration during the aesthetic experience of Chinese calligraphy.Providing evidence that the aesthetic experience of Chinese calligraphy has several similarities with western art while retaining its unique characters as an eastern traditional art form.
