基于Journal of Chemical Education近二十年的载文,从教学主题与内容、教学手段与方法等方面分析研究了国外有关“化学平衡”主题教学课例的基本情况和研究重点。根据具体课例的内容分析,凝练出可以从实验创新与探究、游戏模拟与活动...基于Journal of Chemical Education近二十年的载文,从教学主题与内容、教学手段与方法等方面分析研究了国外有关“化学平衡”主题教学课例的基本情况和研究重点。根据具体课例的内容分析,凝练出可以从实验创新与探究、游戏模拟与活动、信息工具支持这三个方面促进“化学平衡”主题的有效教学,介绍相应的典型课例,以期补充国内关于“化学平衡”主题教学课例的研究,为化学教学研究和实践提供有益参考。展开更多
Recently,the use of natural immunopotentiators,such as plant extracts,is predicted to offer high disease-prevention potential in aquaculture.However,few reports on the immunomodulatory impacts of olive extract(OE)on t...Recently,the use of natural immunopotentiators,such as plant extracts,is predicted to offer high disease-prevention potential in aquaculture.However,few reports on the immunomodulatory impacts of olive extract(OE)on teleost are available.Therefore,the effects of dietary intake of triterpene-enriched OE on black sea bream(Acanthopagrus schlegelii)were investigated in this study.Our data showed that total blood cell counts,in vivo content of lysozyme,activities of antiprotease and myeloperoxidase,and contents of IL-4 and IL-6 were significantly up-regulated by dietary intake of triterpene-enriched OE.Additionally,the hampered immune response induced by cadmium exposure was significantly mitigated by the administration of OE as were indicated by partially or completely rescued immune-relating parameters.Furthermore,the expressions of immune-related genes encoding NF-κB inhibitor alpha(IkBα),tumor necrosis factorα(TNFα),cyclooxygenase-2(COX-2),and proto-oncogene protein c-fos(FOS)were found to be significantly up-regulated by the dietary intake of OE.In general,the results suggested that the dietary intake of triterpene-enriched OE has immune enhancing effect in black sea bream.Such effect may be realized by 1)increasing the total counts of diverse blood cells;2)activating nonspecific immune biomolecules;and 3)affecting signaling pathways such as IKK and ERK and subsequently inducing IL-4 and IL-6 biosyntheses.展开更多
Chen Hengzhe is one of the earliest novelists at the beginning of new literature.Her novels depict the tragic real life with a serious and profound realistic tone and meditate on the emotional problems of life with th...Chen Hengzhe is one of the earliest novelists at the beginning of new literature.Her novels depict the tragic real life with a serious and profound realistic tone and meditate on the emotional problems of life with the unique perspective and delicate psychology of women.Her novels,with the sincerest feelings and pure thoughts,show her desire for individual enlightenment and group enlightenment by means of fairy tales and fables.展开更多
文摘基于Journal of Chemical Education近二十年的载文,从教学主题与内容、教学手段与方法等方面分析研究了国外有关“化学平衡”主题教学课例的基本情况和研究重点。根据具体课例的内容分析,凝练出可以从实验创新与探究、游戏模拟与活动、信息工具支持这三个方面促进“化学平衡”主题的有效教学,介绍相应的典型课例,以期补充国内关于“化学平衡”主题教学课例的研究,为化学教学研究和实践提供有益参考。
基金supported by the National Key R&D Pro-gram of China(No.2018YFD0900603)the National Na-tural Science Foundation of China(No.31672634)the research funding from Innovation Division,Lucta(Guangzhou)Flavours Co.,Ltd
文摘Recently,the use of natural immunopotentiators,such as plant extracts,is predicted to offer high disease-prevention potential in aquaculture.However,few reports on the immunomodulatory impacts of olive extract(OE)on teleost are available.Therefore,the effects of dietary intake of triterpene-enriched OE on black sea bream(Acanthopagrus schlegelii)were investigated in this study.Our data showed that total blood cell counts,in vivo content of lysozyme,activities of antiprotease and myeloperoxidase,and contents of IL-4 and IL-6 were significantly up-regulated by dietary intake of triterpene-enriched OE.Additionally,the hampered immune response induced by cadmium exposure was significantly mitigated by the administration of OE as were indicated by partially or completely rescued immune-relating parameters.Furthermore,the expressions of immune-related genes encoding NF-κB inhibitor alpha(IkBα),tumor necrosis factorα(TNFα),cyclooxygenase-2(COX-2),and proto-oncogene protein c-fos(FOS)were found to be significantly up-regulated by the dietary intake of OE.In general,the results suggested that the dietary intake of triterpene-enriched OE has immune enhancing effect in black sea bream.Such effect may be realized by 1)increasing the total counts of diverse blood cells;2)activating nonspecific immune biomolecules;and 3)affecting signaling pathways such as IKK and ERK and subsequently inducing IL-4 and IL-6 biosyntheses.
文摘Chen Hengzhe is one of the earliest novelists at the beginning of new literature.Her novels depict the tragic real life with a serious and profound realistic tone and meditate on the emotional problems of life with the unique perspective and delicate psychology of women.Her novels,with the sincerest feelings and pure thoughts,show her desire for individual enlightenment and group enlightenment by means of fairy tales and fables.
