BACKGROUND Colorectal cancer is currently the third most common malignant tumor and the second leading cause of cancer-related death worldwide.Neoadjuvant chemoradiotherapy(nCRT)is standard for locally advanced rectal...BACKGROUND Colorectal cancer is currently the third most common malignant tumor and the second leading cause of cancer-related death worldwide.Neoadjuvant chemoradiotherapy(nCRT)is standard for locally advanced rectal cancer(LARC).Except for pathological examination after resection,it is not known exactly whether LARC patients have achieved pathological complete response(pCR)before surgery.To date,there are no clear clinical indicators that can predict the efficacy of nCRT and patient outcomes.AIM To investigate the indicators that can predict pCR and long-term outcomes following nCRT in patients with LARC.METHODS Clinical data of 128 LARC patients admitted to our hospital between September 2013 and November 2022 were retrospectively analyzed.Patients were categorized into pCR and non-pCR groups.Univariate analysis(using the χ^(2) test or Fisher’s exact test)and logistic multivariate regression analysis were used to study clinical predictors affecting pCR.The 5-year disease-free survival(DFS)and overall survival(OS)rates were calculated using Kaplan-Meier analysis,and differences in survival curves were assessed with the log-rank test.RESULTS Univariate analysis showed that pretreatment carcinoembryonic antigen(CEA)level,lymphocyte-monocyte ratio(LMR),time interval between neoadjuvant therapy completion and total mesorectal excision,and tumor size were correlated with pCR.Multivariate results showed that CEA≤5 ng/mL(P=0.039),LMR>2.73(P=0.023),and time interval>10 wk(P=0.039)were independent predictors for pCR.Survival analysis demonstrated that patients in the pCR group had significantly higher 5-year DFS rates(94.7%vs 59.7%,P=0.002)and 5-year OS rates(95.8%vs 80.1%,P=0.019)compared to the non-pCR group.Tumor deposits(TDs)were significantly correlated with shorter DFS(P=0.002)and OS(P<0.001).CONCLUSION Pretreatment CEA,LMR,and time interval contribute to predicting nCRT efficacy in LARC patients.Achieving pCR demonstrates longer DFS and OS.TDs correlate with poor prognosis.展开更多
Objective:To investigate the effects of co-transfection of miR-520c-3p and miR-132 on proliferation and apoptosis of hepatocellular carcinoma Huh7.Methods:Hepatocellular carcinoma Huh7 was cultured in vitro and lipido...Objective:To investigate the effects of co-transfection of miR-520c-3p and miR-132 on proliferation and apoptosis of hepatocellular carcinoma Huh7.Methods:Hepatocellular carcinoma Huh7 was cultured in vitro and lipidosome was used to transfect miR-520c-3p and miR-132 respectively or together.The effects of transfection of miR-520c-3p and miR-132 on proliferation and apoptosis of Huh7 were detected by CCK8 and Annexin V staining and flow cytometry,and the expression level of the targeted gene of over-expressed miR-520c-3p and miR-132 was determined by Western blot and realtime PCR.Results:Compared with the control group,the proliferation ability of Huh7 of the single transfected and co-transfected miR-520c-3p and miR-132 decreased significantly,and the apoptosis ratio increased distinctly(P<0.05).Besides,the affect of the co-transfection group was better than that of the single transfection group.The protein levels of GPC3(Glypican-3) and YAP(Yes-associated protein),the target genes transfected only by miR-520c-3p and miR-132,respectively,reduced obviously(P<0.05),which was similar with the co-infected cells,but cells transfected by miR-132 only showed a decrease of YAP.Conclusions:The co-transfection of miR-520c-3p and miR-132 can target-regulate the expression of GPC3 and YAP,enhance the exhibition effect on proliferation of hepatocellular carcinoma Huh7 and induce cell apoptosis synergistically.展开更多
This study presents signatures of seismo-ionospheric perturbations possibly related to the 14 July 2019 M_(w)7.2 Laiwui earthquake,detected by a cross-validation analysis of total electron content(TEC)data of the glob...This study presents signatures of seismo-ionospheric perturbations possibly related to the 14 July 2019 M_(w)7.2 Laiwui earthquake,detected by a cross-validation analysis of total electron content(TEC)data of the global ionospheric map(GIM)from GPS and plasma parameter data recorded by the China Seismo-Electromagnetic Satellite(CSES).After separating pre-seismic ionospheric phenomena from the ionospheric disturbances due to the magnetospheric and solar activities,we have identified three positive temporal anomalies,around the epicenter,at 1 day,3 days and 8 days before the earthquake(14 July 2019),along with a negative anomaly 6 days after the earthquake.These results agree well with the TEC spatial variations in latitude-longitude-time(LLT)maps.To confirm these anomalies further,we employed the moving mean method(MMM)to analyze ionospheric plasma parameters(electron,O^(+) and He^(+) densities)recorded by the Langmuir probe(LAP)and Plasma Analyzer Package(PAP)onboard the CSES.The analysis detected on,on Day Two,Day Four,and Day Seven before the earthquake,remarkable enhancements along the orbits around when in proximity to the epicenter.To make the investigations still more convincing,we compared the orbits on which anomalous readings were recorded to their corresponding four nearest revisiting orbits;the comparison did indeed indicate the existence of plasma parameter anomalies that appear to be associated with the Laiwui earthquake.All these results ilustrate that the unusual ionospheric perturbations detected through GPS and CSES data are possibly associated with the M_(w)7.2 Laiwui earthquake,which suggests that at least some earthquakes may be predicted by alertness to pre-seismic ionospheric anomalies over regions known to be at seismic risk.This case study also contributes additional information of value to our understanding of lithosphere-atmosphere-ionosphere coupling.展开更多
Objective:To study the change of the peripheral blood immune pattern and its correlation with prognosis in patients with liver cancer after treated by sorafenib.Methods:Patients with advanced liver cancer admitted in ...Objective:To study the change of the peripheral blood immune pattern and its correlation with prognosis in patients with liver cancer after treated by sorafenib.Methods:Patients with advanced liver cancer admitted in our hospital were enrolled and treated with sorafenib.After two months of the treatment,their peripheral blood was collected.The immune cell subset and cytokines level were determined by flow cytometry and luminex technology.According to the reaction expressed by patients towards sorafenib,patients were divided into the response group and the no response group.The changes of the peripheral blood immune pattern and its correlation with prognosis of patients in the two groups were compared.Results:Before and after treatment of sorafenib,there was no significant difference in the ratios of T cells,NK cells and their subtypes in peripheral blood of patients between the two groups;while after treatment the ratio of B cells and regulatory B cells(Breg) of patients in the response group was significant higher than that of the no response group(P<0.05),and the prognosis conditions of patients with decreased ratio of Breg cells were better than other patients after undergoing chemotherapy.The levels of plasma cytokines IL-6,IL-10,IL-12,IL17,FIL-3L,IFN- γ,TNF-α,MCP-1 and VEGF showed no significant differences.Conclusions:After treatment of sorafenib,the prognosis conditions of patients of advanced liver cancer with a reduced Breg ratio are better than patients with an unaltered or increased Breg ratio.The ratio of Breg in peripheral blood may be considered as early biological indicator for the prediction of the curative effects of sorafenib.展开更多
In recent years,the IT industry in China has developed rapidly and made remarkable achievements.However,there is still a big gap between China and foreign countries in the core fields of information technology,such as...In recent years,the IT industry in China has developed rapidly and made remarkable achievements.However,there is still a big gap between China and foreign countries in the core fields of information technology,such as system hardware and software platform.Currently,foreign countries have gradually raised the restrictions of information technology in China,and even added many domestic enterprises to the restricted list,which has rung the alarm to the information security of the country.Therefore,in order to break through the foreign technology blockade and find a unique way in independent software and hardware platform,it is urgent to carry out the curriculum construction and talent training mechanism on core software and hardware platform.HarmonyOS is a“future-oriented”distributed operating system developed by Huawei.It proposes a distributed concept based on the same system capability and adapts to a variety of terminal forms,and supports a variety of terminal devices such as mobile phones,watches and smart screens.Our course on HarmonyOS aims to increase the theoretical knowledge of the core independent software and hardware platform.In the course,we exploit our teaching reform experience in the course of“Mobile Application Development”,and investigate the teaching mechanism of HarmonyOS to contribute to the rapid development of information technology and ecological construction in China.展开更多
Mobile Application Development is a well-known undergraduate specialized course majoring in Computer Science and Software Engineering.Since it is a rapid developing technique and requires extensive project samples to ...Mobile Application Development is a well-known undergraduate specialized course majoring in Computer Science and Software Engineering.Since it is a rapid developing technique and requires extensive project samples to help understand,current teaching mechanism has still limitations in rare real project examples,outdated course contents,and lack of automatic assessment platforms.In order to improve the teaching effects and cultivate students’practical ability,we employ this teaching reform with industrial projects,double instructors,and automatic assessment platform to allow students participating in every course process.We aim to improve students’practical and collaboration ability during conducting the project spontaneously,and cultivate their awareness of self-learning and lifelong learning.Our classroom feedback has demonstrated that this teaching reform is effective on improving students’practical abilities,learning initiatives and comprehensive qualities.展开更多
The emergence of the Harmony operating system independently developed by Huawei has provided new opportunities and challenges for the development of our country’s information industry.This paper mainly introduces how...The emergence of the Harmony operating system independently developed by Huawei has provided new opportunities and challenges for the development of our country’s information industry.This paper mainly introduces how to combine ideological and political education with mobile devices software development via Harmony OS development courses,aiming to cultivate students’ability to develop applications under the Harmony OS operating system independently or in groups,as well as achieving the patriotism and national mission.展开更多
Here,a metal-organic framework(MOF)-templated strategy was applied to synthesize the CoCeO_(x) bimetallic catalysts by calcining Co partially-substituted Ce-UiO-66.It is indicated that the substituted Co limited Ce ca...Here,a metal-organic framework(MOF)-templated strategy was applied to synthesize the CoCeO_(x) bimetallic catalysts by calcining Co partially-substituted Ce-UiO-66.It is indicated that the substituted Co limited Ce cations in Ce-UiO-66 framework,which affects its growth and structure crystallinity to some extent.After pyrolysis treatment,the derived bimetallic oxide(CoCeO_(x)-M)can basically keep the octahedral structure and the surface area is much higher than the bulk metal composite oxide(CoCeO_(x)-B)prepared by traditional coprecipitation.Results reveal that CoCeO_(x)-M performs the best chlorobenzene degradation capacity,superior stability and vapor tolerance compared with those of CeO_(2)-M(derived from Ce-UiO-66)and CoCeO_(x)-B.At the same time,it is favorable to inhibit the formation of CO during the oxidation reaction.The superior catalytic performance of CoCeO_(x)-M is attributed to a good dispersion of metal cations,high surface area and active oxygen concentration,and good redox property.Moreover,the formation of organic byproducts especially chlorinated organics can be obviously prohibited over CoCeO_(x)-M compared with that of CeO_(2)-M.Mechanism study reveals that chlorobenzene dissociates on the surface of CoCeO_(x)-M to form carboxylates such as acetate species,maleate and phenolate before finally oxidized into CO_(2),H_(2)O,and HCl.The present work poses new insights into the fabrication of efficient catalysts for industrial CVOC purification.展开更多
As for machine vision-based intelligent system in the application of discriminating and sorting the sex of silkworm pupae,the tail gonad was the unique physiological feature.However,motion blur,resulting from the live...As for machine vision-based intelligent system in the application of discriminating and sorting the sex of silkworm pupae,the tail gonad was the unique physiological feature.However,motion blur,resulting from the live silkworm pupa’s writhing motion at the moment of capturing image,could lose textures and structures(such as edge and tail gonad etc.)dramatically,which casted great challenges for sex identification.To increase the image quality and relieve the difficulty of discrimination caused by motion blur,an effective approach that including three stages was proposed in this work.In the image prediction stage,first sharp edges were acquired by using filtering techniques.Then the initial blur kernel was computed with Gaussian prior.The coarse version latent image was deconvoluted in the Fourier domain.In the kernel refinement stage,the Radon transform was applied to estimate the accurate kernel.In the final restoration step,a TV-L1 deconvolution model was carried out to obtain a better result.The experimental results showed that benefiting from the prediction step and kernel refinement step,the kernel was more accurate and the recovered image contained much more textures.It revealed that the proposed method was useful in removing the motion blur.Furthermore,the method could also be applied to other fields.展开更多
With cloud computing technology becoming more mature, it is essential to combine the big data processing tool Hadoop with the Infrastructure as a Service（Iaa S） cloud platform. In this study, we first propose a new ...With cloud computing technology becoming more mature, it is essential to combine the big data processing tool Hadoop with the Infrastructure as a Service（Iaa S） cloud platform. In this study, we first propose a new Dynamic Hadoop Cluster on Iaa S（DHCI） architecture, which includes four key modules： monitoring,scheduling, Virtual Machine（VM） management, and VM migration modules. The load of both physical hosts and VMs is collected by the monitoring module and can be used to design resource scheduling and data locality solutions. Second, we present a simple load feedback-based resource scheduling scheme. The resource allocation can be avoided on overburdened physical hosts or the strong scalability of virtual cluster can be achieved by fluctuating the number of VMs. To improve the flexibility, we adopt the separated deployment of the computation and storage VMs in the DHCI architecture, which negatively impacts the data locality. Third, we reuse the method of VM migration and propose a dynamic migration-based data locality scheme using parallel computing entropy. We migrate the computation nodes to different host（s） or rack（s） where the corresponding storage nodes are deployed to satisfy the requirement of data locality. We evaluate our solutions in a realistic scenario based on Open Stack.Substantial experimental results demonstrate the effectiveness of our solutions that contribute to balance the workload and performance improvement, even under heavy-loaded cloud system conditions.展开更多
With respect to security, the use of various terminals in the mobile Internet environment is problematic.Traditional terminal testing methods cannot simulate actual testing environments; thus, the test results do not ...With respect to security, the use of various terminals in the mobile Internet environment is problematic.Traditional terminal testing methods cannot simulate actual testing environments; thus, the test results do not accurately reflect the security of terminals. To address this problem, we designed and developed a cloud platform based automated testing system for the mobile Internet. In this system, virtualization and automation technology are utilized to integrate mobile terminals into the cloud platform as a resource, to achieve a novel cloud service called Testing as a Service(Taa S). The system consists of three functional modules: web front-end module, testing environment module, and automated testing module. We adopted the permeable automated testing tool Metasploit to perform security testing. In our test experiments, we selected 100 apps with diverse vulnerability levels, ranging from secure to vulnerable, to perform a series of functional tests. The experimental results show that this system can correctly test both the number of vulnerable apps and their corresponding vulnerability levels. As such, the designed system can flexibly configure various testing environments for different testing cases or projects, and thereby perform security testing automatically.展开更多
基金Supported by the National Natural Science Foundation of China,No.82073476the National Key R&D Program of China,No.2022YFC2503700 and No.2022YFC2503703+1 种基金Jiangsu Provincial Medical Key Discipline,No.ZDXK202235Innovation Research Project of Medical and Industrial Cooperation in Suzhou,No.SLJ2021005.
文摘BACKGROUND Colorectal cancer is currently the third most common malignant tumor and the second leading cause of cancer-related death worldwide.Neoadjuvant chemoradiotherapy(nCRT)is standard for locally advanced rectal cancer(LARC).Except for pathological examination after resection,it is not known exactly whether LARC patients have achieved pathological complete response(pCR)before surgery.To date,there are no clear clinical indicators that can predict the efficacy of nCRT and patient outcomes.AIM To investigate the indicators that can predict pCR and long-term outcomes following nCRT in patients with LARC.METHODS Clinical data of 128 LARC patients admitted to our hospital between September 2013 and November 2022 were retrospectively analyzed.Patients were categorized into pCR and non-pCR groups.Univariate analysis(using the χ^(2) test or Fisher’s exact test)and logistic multivariate regression analysis were used to study clinical predictors affecting pCR.The 5-year disease-free survival(DFS)and overall survival(OS)rates were calculated using Kaplan-Meier analysis,and differences in survival curves were assessed with the log-rank test.RESULTS Univariate analysis showed that pretreatment carcinoembryonic antigen(CEA)level,lymphocyte-monocyte ratio(LMR),time interval between neoadjuvant therapy completion and total mesorectal excision,and tumor size were correlated with pCR.Multivariate results showed that CEA≤5 ng/mL(P=0.039),LMR>2.73(P=0.023),and time interval>10 wk(P=0.039)were independent predictors for pCR.Survival analysis demonstrated that patients in the pCR group had significantly higher 5-year DFS rates(94.7%vs 59.7%,P=0.002)and 5-year OS rates(95.8%vs 80.1%,P=0.019)compared to the non-pCR group.Tumor deposits(TDs)were significantly correlated with shorter DFS(P=0.002)and OS(P<0.001).CONCLUSION Pretreatment CEA,LMR,and time interval contribute to predicting nCRT efficacy in LARC patients.Achieving pCR demonstrates longer DFS and OS.TDs correlate with poor prognosis.
基金supported by Supported by Education Department of Hubei Province science and technology research project(NO.B2015230)Applied Fundamental Research Project of Wuhan Municipal Science and Technology Bureau(Grant No.2015061701011630)+1 种基金Medical Scientific Research Project of Health and Familly Planning Commission of Wuhan Municipality(Grant No.WX16E12)the fourth batch of "Hanyang Talent Associate Program"
文摘Objective:To investigate the effects of co-transfection of miR-520c-3p and miR-132 on proliferation and apoptosis of hepatocellular carcinoma Huh7.Methods:Hepatocellular carcinoma Huh7 was cultured in vitro and lipidosome was used to transfect miR-520c-3p and miR-132 respectively or together.The effects of transfection of miR-520c-3p and miR-132 on proliferation and apoptosis of Huh7 were detected by CCK8 and Annexin V staining and flow cytometry,and the expression level of the targeted gene of over-expressed miR-520c-3p and miR-132 was determined by Western blot and realtime PCR.Results:Compared with the control group,the proliferation ability of Huh7 of the single transfected and co-transfected miR-520c-3p and miR-132 decreased significantly,and the apoptosis ratio increased distinctly(P<0.05).Besides,the affect of the co-transfection group was better than that of the single transfection group.The protein levels of GPC3(Glypican-3) and YAP(Yes-associated protein),the target genes transfected only by miR-520c-3p and miR-132,respectively,reduced obviously(P<0.05),which was similar with the co-infected cells,but cells transfected by miR-132 only showed a decrease of YAP.Conclusions:The co-transfection of miR-520c-3p and miR-132 can target-regulate the expression of GPC3 and YAP,enhance the exhibition effect on proliferation of hepatocellular carcinoma Huh7 and induce cell apoptosis synergistically.
基金a project funded by China National Space Administration (CNSA)China Earthquake Administration (CEA)+1 种基金supported by the National Natural Science Foundation of China (Grant No. 42004137)the Natural Science Foundation of Sichuan Province of China (Grant No. 22NSFSC3946)
文摘This study presents signatures of seismo-ionospheric perturbations possibly related to the 14 July 2019 M_(w)7.2 Laiwui earthquake,detected by a cross-validation analysis of total electron content(TEC)data of the global ionospheric map(GIM)from GPS and plasma parameter data recorded by the China Seismo-Electromagnetic Satellite(CSES).After separating pre-seismic ionospheric phenomena from the ionospheric disturbances due to the magnetospheric and solar activities,we have identified three positive temporal anomalies,around the epicenter,at 1 day,3 days and 8 days before the earthquake(14 July 2019),along with a negative anomaly 6 days after the earthquake.These results agree well with the TEC spatial variations in latitude-longitude-time(LLT)maps.To confirm these anomalies further,we employed the moving mean method(MMM)to analyze ionospheric plasma parameters(electron,O^(+) and He^(+) densities)recorded by the Langmuir probe(LAP)and Plasma Analyzer Package(PAP)onboard the CSES.The analysis detected on,on Day Two,Day Four,and Day Seven before the earthquake,remarkable enhancements along the orbits around when in proximity to the epicenter.To make the investigations still more convincing,we compared the orbits on which anomalous readings were recorded to their corresponding four nearest revisiting orbits;the comparison did indeed indicate the existence of plasma parameter anomalies that appear to be associated with the Laiwui earthquake.All these results ilustrate that the unusual ionospheric perturbations detected through GPS and CSES data are possibly associated with the M_(w)7.2 Laiwui earthquake,which suggests that at least some earthquakes may be predicted by alertness to pre-seismic ionospheric anomalies over regions known to be at seismic risk.This case study also contributes additional information of value to our understanding of lithosphere-atmosphere-ionosphere coupling.
基金supported by the Applied Basic Research Project of Wuhan Municipal Science and Technology Bureau(Grant No.2015061701011630,NO.2013062301010823)Medical Scientific Research project of the Education Department of Hubei Province(Grant No.B2015230)the fourth batch of Hanyang Concert Talent Plan
文摘Objective:To study the change of the peripheral blood immune pattern and its correlation with prognosis in patients with liver cancer after treated by sorafenib.Methods:Patients with advanced liver cancer admitted in our hospital were enrolled and treated with sorafenib.After two months of the treatment,their peripheral blood was collected.The immune cell subset and cytokines level were determined by flow cytometry and luminex technology.According to the reaction expressed by patients towards sorafenib,patients were divided into the response group and the no response group.The changes of the peripheral blood immune pattern and its correlation with prognosis of patients in the two groups were compared.Results:Before and after treatment of sorafenib,there was no significant difference in the ratios of T cells,NK cells and their subtypes in peripheral blood of patients between the two groups;while after treatment the ratio of B cells and regulatory B cells(Breg) of patients in the response group was significant higher than that of the no response group(P<0.05),and the prognosis conditions of patients with decreased ratio of Breg cells were better than other patients after undergoing chemotherapy.The levels of plasma cytokines IL-6,IL-10,IL-12,IL17,FIL-3L,IFN- γ,TNF-α,MCP-1 and VEGF showed no significant differences.Conclusions:After treatment of sorafenib,the prognosis conditions of patients of advanced liver cancer with a reduced Breg ratio are better than patients with an unaltered or increased Breg ratio.The ratio of Breg in peripheral blood may be considered as early biological indicator for the prediction of the curative effects of sorafenib.
文摘In recent years,the IT industry in China has developed rapidly and made remarkable achievements.However,there is still a big gap between China and foreign countries in the core fields of information technology,such as system hardware and software platform.Currently,foreign countries have gradually raised the restrictions of information technology in China,and even added many domestic enterprises to the restricted list,which has rung the alarm to the information security of the country.Therefore,in order to break through the foreign technology blockade and find a unique way in independent software and hardware platform,it is urgent to carry out the curriculum construction and talent training mechanism on core software and hardware platform.HarmonyOS is a“future-oriented”distributed operating system developed by Huawei.It proposes a distributed concept based on the same system capability and adapts to a variety of terminal forms,and supports a variety of terminal devices such as mobile phones,watches and smart screens.Our course on HarmonyOS aims to increase the theoretical knowledge of the core independent software and hardware platform.In the course,we exploit our teaching reform experience in the course of“Mobile Application Development”,and investigate the teaching mechanism of HarmonyOS to contribute to the rapid development of information technology and ecological construction in China.
文摘Mobile Application Development is a well-known undergraduate specialized course majoring in Computer Science and Software Engineering.Since it is a rapid developing technique and requires extensive project samples to help understand,current teaching mechanism has still limitations in rare real project examples,outdated course contents,and lack of automatic assessment platforms.In order to improve the teaching effects and cultivate students’practical ability,we employ this teaching reform with industrial projects,double instructors,and automatic assessment platform to allow students participating in every course process.We aim to improve students’practical and collaboration ability during conducting the project spontaneously,and cultivate their awareness of self-learning and lifelong learning.Our classroom feedback has demonstrated that this teaching reform is effective on improving students’practical abilities,learning initiatives and comprehensive qualities.
文摘The emergence of the Harmony operating system independently developed by Huawei has provided new opportunities and challenges for the development of our country’s information industry.This paper mainly introduces how to combine ideological and political education with mobile devices software development via Harmony OS development courses,aiming to cultivate students’ability to develop applications under the Harmony OS operating system independently or in groups,as well as achieving the patriotism and national mission.
基金Project supported by the National Natural Science Foundation of China(22106124,22276145)the Natural Science Foundation of Shaanxi Province(2021JQ-011).
文摘Here,a metal-organic framework(MOF)-templated strategy was applied to synthesize the CoCeO_(x) bimetallic catalysts by calcining Co partially-substituted Ce-UiO-66.It is indicated that the substituted Co limited Ce cations in Ce-UiO-66 framework,which affects its growth and structure crystallinity to some extent.After pyrolysis treatment,the derived bimetallic oxide(CoCeO_(x)-M)can basically keep the octahedral structure and the surface area is much higher than the bulk metal composite oxide(CoCeO_(x)-B)prepared by traditional coprecipitation.Results reveal that CoCeO_(x)-M performs the best chlorobenzene degradation capacity,superior stability and vapor tolerance compared with those of CeO_(2)-M(derived from Ce-UiO-66)and CoCeO_(x)-B.At the same time,it is favorable to inhibit the formation of CO during the oxidation reaction.The superior catalytic performance of CoCeO_(x)-M is attributed to a good dispersion of metal cations,high surface area and active oxygen concentration,and good redox property.Moreover,the formation of organic byproducts especially chlorinated organics can be obviously prohibited over CoCeO_(x)-M compared with that of CeO_(2)-M.Mechanism study reveals that chlorobenzene dissociates on the surface of CoCeO_(x)-M to form carboxylates such as acetate species,maleate and phenolate before finally oxidized into CO_(2),H_(2)O,and HCl.The present work poses new insights into the fabrication of efficient catalysts for industrial CVOC purification.
基金The research was financially supported by Chongqing Science and Technology Commission Projects under Grant No.cstc2013yykfA80015 and Grant No.cstc2017shms-xdny80080Fundamental Research Funds for the Central Universities under Grant No.XDJK2016A007,XDJK2018D011Doctoral Scientific Research Foundation of Southwest University Project Grant No.SWU114109.
文摘As for machine vision-based intelligent system in the application of discriminating and sorting the sex of silkworm pupae,the tail gonad was the unique physiological feature.However,motion blur,resulting from the live silkworm pupa’s writhing motion at the moment of capturing image,could lose textures and structures(such as edge and tail gonad etc.)dramatically,which casted great challenges for sex identification.To increase the image quality and relieve the difficulty of discrimination caused by motion blur,an effective approach that including three stages was proposed in this work.In the image prediction stage,first sharp edges were acquired by using filtering techniques.Then the initial blur kernel was computed with Gaussian prior.The coarse version latent image was deconvoluted in the Fourier domain.In the kernel refinement stage,the Radon transform was applied to estimate the accurate kernel.In the final restoration step,a TV-L1 deconvolution model was carried out to obtain a better result.The experimental results showed that benefiting from the prediction step and kernel refinement step,the kernel was more accurate and the recovered image contained much more textures.It revealed that the proposed method was useful in removing the motion blur.Furthermore,the method could also be applied to other fields.
基金supported by the Open Project Program of Jiangsu High Technology Research Key Laboratory for Wireless Sensor Networks(No.WSNLBKF201503)the Fundamental Research Funds for the Central Universities(No.2016JBM011)+2 种基金Fundamental Research Funds for the Central Universities(No.2014ZD03-03)the Priority Academic Program Development of Jiangsu Higher Education InstitutionsJiangsu Collaborative Innovation Center on Atmospheric Environment and Equipment Technology
文摘With cloud computing technology becoming more mature, it is essential to combine the big data processing tool Hadoop with the Infrastructure as a Service（Iaa S） cloud platform. In this study, we first propose a new Dynamic Hadoop Cluster on Iaa S（DHCI） architecture, which includes four key modules： monitoring,scheduling, Virtual Machine（VM） management, and VM migration modules. The load of both physical hosts and VMs is collected by the monitoring module and can be used to design resource scheduling and data locality solutions. Second, we present a simple load feedback-based resource scheduling scheme. The resource allocation can be avoided on overburdened physical hosts or the strong scalability of virtual cluster can be achieved by fluctuating the number of VMs. To improve the flexibility, we adopt the separated deployment of the computation and storage VMs in the DHCI architecture, which negatively impacts the data locality. Third, we reuse the method of VM migration and propose a dynamic migration-based data locality scheme using parallel computing entropy. We migrate the computation nodes to different host（s） or rack（s） where the corresponding storage nodes are deployed to satisfy the requirement of data locality. We evaluate our solutions in a realistic scenario based on Open Stack.Substantial experimental results demonstrate the effectiveness of our solutions that contribute to balance the workload and performance improvement, even under heavy-loaded cloud system conditions.
基金supported by the National Natural Science Foundation of China (No. 61202431)the National High-Tech Research and Development (863) Program of China (No. 2013AA014702)+2 种基金Beijing Higher Education Young Elite Teacher Project (No. YETP0535)the Open Project Program of Jiangsu High Technology Research Key Laboratory for Wireless Sensor Networksthe Scientific Research Foundation for the Returned Overseas Chinese Scholars, Ministry of Education
文摘With respect to security, the use of various terminals in the mobile Internet environment is problematic.Traditional terminal testing methods cannot simulate actual testing environments; thus, the test results do not accurately reflect the security of terminals. To address this problem, we designed and developed a cloud platform based automated testing system for the mobile Internet. In this system, virtualization and automation technology are utilized to integrate mobile terminals into the cloud platform as a resource, to achieve a novel cloud service called Testing as a Service(Taa S). The system consists of three functional modules: web front-end module, testing environment module, and automated testing module. We adopted the permeable automated testing tool Metasploit to perform security testing. In our test experiments, we selected 100 apps with diverse vulnerability levels, ranging from secure to vulnerable, to perform a series of functional tests. The experimental results show that this system can correctly test both the number of vulnerable apps and their corresponding vulnerability levels. As such, the designed system can flexibly configure various testing environments for different testing cases or projects, and thereby perform security testing automatically.
