期刊文献+
共找到1篇文章
< 1 >
每页显示 20 50 100
Irritable bowel syndrome and small intestinal bacterial overgrowth:Meaningful association or unnecessary hype 被引量:29
1
作者 Uday C Ghoshal deepakshi srivastava 《World Journal of Gastroenterology》 SCIE CAS 2014年第10期2482-2491,共10页
Irritable bowel syndrome (IBS) is a common condition characterized by abdominal pain or discomfort, bloating, and altered stool form and passage. Small intestinal bacterial overgrowth (SIBO) is a condition in which th... Irritable bowel syndrome (IBS) is a common condition characterized by abdominal pain or discomfort, bloating, and altered stool form and passage. Small intestinal bacterial overgrowth (SIBO) is a condition in which there is overgrowth of bacteria in small bowel in excess of 10<sup>5</sup> colony forming units per milliliter on culture of the upper gut aspirate. Frequency of SIBO varied from 4%-78% among patients with IBS and from 1%-40% among controls. Higher frequency in some studies might be due to fallacious criteria [post-lactulose breath-hydrogen rise 20 PPM above basal within 90 min (early-peak)]. Glucose hydrogen breath test (GHBT) has a low sensitivity to diagnose SIBO. Hence, studies based on GHBT might have under-estimated frequency of SIBO. Therefore, it is important to analyze these studies carefully to evaluate whether the reported association between IBS and SIBO is over or under-projected. This review evaluates studies on association between SIBO and IBS, discordance between different studies, their strength and weakness including methodological issues and evidence on therapeutic manipulation of gut flora on symptoms of IBS. 展开更多
关键词 Glucose hydrogen breath test Lactulose hydrogen breath test Functional bowel disease DYSBIOSIS Gut flora
下载PDF
上一页 1 下一页 到第
使用帮助 返回顶部