AIM:To evaluate the efficacy and safety of silicone oil(SO)as a corneal lubricant to improve visualization during vitrectomy.METHODS:Patients who underwent vitreoretinal surgery were divided into two groups.Group 1 wa...AIM:To evaluate the efficacy and safety of silicone oil(SO)as a corneal lubricant to improve visualization during vitrectomy.METHODS:Patients who underwent vitreoretinal surgery were divided into two groups.Group 1 was operated on with initial SO(Oxane 5700)as a corneal lubricant.Group 2 was operated on with initial lactated ringer’s solution(LRS)and then replaced with SO as required.Fundus clarity was scored during the surgery.Fluorescein staining was performed to determine the damage to corneal epithelium.RESULTS:Totally 114 eyes of 114 patients were included.Single SO use maintained a clear cornea and provided excellent visualization of surgical image.In group 1,the fundus clarity was grade 3 in 41/45 eyes and grade 2 in 4/45 eyes.In group 2,corneal edema frequently occurred after initial LRS use.The fundus clarity was grade 3 in 19/69 eyes,2 in 37/69 eyes and 1 in 13/69 eyes(P<0.05).SO was applied in 29 eyes of initial LRS use with subsequent corneal edema,which eliminated the corneal edema in 26 eyes.Corneal fluorescein staining score in group 1 was 0 in 28 eyes,1 in 11 eyes and 2 in 6 eyes,and 40,20 and 9,respectively,in group 2(all P>0.05).CONCLUSION:The use of SO as a corneal lubricant is effective and safe for preserving and improving corneal clarity and providing clear surgical field during vitrectomy.展开更多
AIM: To investigate the epidemiologic characteristics and outcomes of open globe injury in Shanghai.METHODS: A retrospective study was conducted for 148 unilateral open globe injury cases presenting to a tertiary refe...AIM: To investigate the epidemiologic characteristics and outcomes of open globe injury in Shanghai.METHODS: A retrospective study was conducted for 148 unilateral open globe injury cases presenting to a tertiary referral hospital of Shanghai. Electronic medical records were reviewed and phone surveys were conducted to collect and analyze 1) background of patient; 2) setting of injury and clinical signs at presentation; 3) treatment procedure and outcome; 4) quality of life after injury. RESULTS: There were more male patients(77.03%) than females(22.97%),more temporary habitants(79.05%)than residents(20.95%). The subjects in this study presented a significantly lower constitutional status of education than that of the whole Shanghai population(P<0.001). Occupational injury was the first cause of injuries(39.86%),followed by home accident(20.27%),road accident(16.89%),violent behavior(16.89%) and outdoor injury(6.08%). The 143 subjects(96.62%) were not wearing spectacles at the time of injury. Of all patients,77subjects(52.03%) had the outcome of no vision(including enucleation). The classification and regression tree(CART)prognosis presents 59.58% sensitivity to predict visual survival correctly and 80.19% specificity to predict no vision correctly. The patients whose injured eye had no vision reported more reduction of life quality. CONCLUSION: We found that male subject,temporary habitants,low educational status and no eyewear are risk factors of open globe injury in Shanghai. Occupational injury is the leading cause. CART analysis presents a certain agreement to the actual visual outcome. The injury imposes negative impact on quality of life especially in no vision cases. The education of eye protection may help to avoid the injury.展开更多
AIM:To introduce a simple resistance controlled suprachoroidal space(SCS)injection technique using a disposable 30-gauge needle connected to a 1 m L syringe and evaluate the effectiveness and applicability of this tec...AIM:To introduce a simple resistance controlled suprachoroidal space(SCS)injection technique using a disposable 30-gauge needle connected to a 1 m L syringe and evaluate the effectiveness and applicability of this technique in the treatment of macular edema.METHODS:A total of 20 patients with various types of macular edema were subjected to a resistance controlled SCS injection of triamcinolone acetonide(TA)with a disposable 30-gauge needle connected to a 1 m L syringe.This technique allows the easy and smooth injection of the TA only once the tip of the needle reached the potential SCS which was indicated by the lower resistance on the plunger.The main outcome measures were anterior segment spectral-domain optical coherence tomography(AS-OCT)measurements post-operation immediately and central subfield thickness(CST),best-corrected visual acuity(BCVA),and intraocular pressure(IOP)measurements at 3mo postoperation.RESULTS:AS-OCT examination showed the expansion of the SCS near the injection site immediately after SCS injection.At three months of follow-up,as compared to the baseline,the mean CST was significantly decreased from 535.0±157.24 to 319.55±127.30μm(P<0.001),the mean BCVA was significantly improved from 1.05±0.41 to 0.73±0.41 log MAR(P<0.001),and the mean IOP was not significantly different,from 15.05±2.54 to 15.85±3.60 mm Hg(P=0.185).Any complication related to the injection procedure including cataract,choroidal and retinal hemorrhage,retinal detachment,or endophthalmitis was not observed in this study.CONCLUSION:The simple and minimally invasive technique of SCS injection of TA with a disposable 30-gauge needle connected to a 1 m L syringe is useful and applicable for macular edema.展开更多
To the Editor:While it is only occasionally clinical significance,multiple bilateral iridociliary cysts are commonly encountered.With the cysts progressively growing larger,they may result in vision obstruction, glauc...To the Editor:While it is only occasionally clinical significance,multiple bilateral iridociliary cysts are commonly encountered.With the cysts progressively growing larger,they may result in vision obstruction, glaucoma,or other ocular problems.[1] Here,we reported an unusual case of multiple ciliary cysts triggering glare with the treatment of neodymium-doped yttrium aluminium garnet (Nd:YAG)laser cystectomy.展开更多
基金Supported by the Shanghai Key Clinical Specialty,Shanghai Eye Disease Research Center(No.2022ZZ01003)the Science and Technology Commission of Shanghai(No.20DZ2270800).
文摘AIM:To evaluate the efficacy and safety of silicone oil(SO)as a corneal lubricant to improve visualization during vitrectomy.METHODS:Patients who underwent vitreoretinal surgery were divided into two groups.Group 1 was operated on with initial SO(Oxane 5700)as a corneal lubricant.Group 2 was operated on with initial lactated ringer’s solution(LRS)and then replaced with SO as required.Fundus clarity was scored during the surgery.Fluorescein staining was performed to determine the damage to corneal epithelium.RESULTS:Totally 114 eyes of 114 patients were included.Single SO use maintained a clear cornea and provided excellent visualization of surgical image.In group 1,the fundus clarity was grade 3 in 41/45 eyes and grade 2 in 4/45 eyes.In group 2,corneal edema frequently occurred after initial LRS use.The fundus clarity was grade 3 in 19/69 eyes,2 in 37/69 eyes and 1 in 13/69 eyes(P<0.05).SO was applied in 29 eyes of initial LRS use with subsequent corneal edema,which eliminated the corneal edema in 26 eyes.Corneal fluorescein staining score in group 1 was 0 in 28 eyes,1 in 11 eyes and 2 in 6 eyes,and 40,20 and 9,respectively,in group 2(all P>0.05).CONCLUSION:The use of SO as a corneal lubricant is effective and safe for preserving and improving corneal clarity and providing clear surgical field during vitrectomy.
基金Supported by the National Natural Science Foundation of China(No.31600971)The Shanghai Committee of Science and Technology,China(No.14411968000)
文摘AIM: To investigate the epidemiologic characteristics and outcomes of open globe injury in Shanghai.METHODS: A retrospective study was conducted for 148 unilateral open globe injury cases presenting to a tertiary referral hospital of Shanghai. Electronic medical records were reviewed and phone surveys were conducted to collect and analyze 1) background of patient; 2) setting of injury and clinical signs at presentation; 3) treatment procedure and outcome; 4) quality of life after injury. RESULTS: There were more male patients(77.03%) than females(22.97%),more temporary habitants(79.05%)than residents(20.95%). The subjects in this study presented a significantly lower constitutional status of education than that of the whole Shanghai population(P<0.001). Occupational injury was the first cause of injuries(39.86%),followed by home accident(20.27%),road accident(16.89%),violent behavior(16.89%) and outdoor injury(6.08%). The 143 subjects(96.62%) were not wearing spectacles at the time of injury. Of all patients,77subjects(52.03%) had the outcome of no vision(including enucleation). The classification and regression tree(CART)prognosis presents 59.58% sensitivity to predict visual survival correctly and 80.19% specificity to predict no vision correctly. The patients whose injured eye had no vision reported more reduction of life quality. CONCLUSION: We found that male subject,temporary habitants,low educational status and no eyewear are risk factors of open globe injury in Shanghai. Occupational injury is the leading cause. CART analysis presents a certain agreement to the actual visual outcome. The injury imposes negative impact on quality of life especially in no vision cases. The education of eye protection may help to avoid the injury.
基金Supported by National Natural Science Foundation of China(No.82101179)Shanghai Sailing Program(No.21YF1422900)the Science and Technology Commission of Shanghai(No.17DZ2260100)。
文摘AIM:To introduce a simple resistance controlled suprachoroidal space(SCS)injection technique using a disposable 30-gauge needle connected to a 1 m L syringe and evaluate the effectiveness and applicability of this technique in the treatment of macular edema.METHODS:A total of 20 patients with various types of macular edema were subjected to a resistance controlled SCS injection of triamcinolone acetonide(TA)with a disposable 30-gauge needle connected to a 1 m L syringe.This technique allows the easy and smooth injection of the TA only once the tip of the needle reached the potential SCS which was indicated by the lower resistance on the plunger.The main outcome measures were anterior segment spectral-domain optical coherence tomography(AS-OCT)measurements post-operation immediately and central subfield thickness(CST),best-corrected visual acuity(BCVA),and intraocular pressure(IOP)measurements at 3mo postoperation.RESULTS:AS-OCT examination showed the expansion of the SCS near the injection site immediately after SCS injection.At three months of follow-up,as compared to the baseline,the mean CST was significantly decreased from 535.0±157.24 to 319.55±127.30μm(P<0.001),the mean BCVA was significantly improved from 1.05±0.41 to 0.73±0.41 log MAR(P<0.001),and the mean IOP was not significantly different,from 15.05±2.54 to 15.85±3.60 mm Hg(P=0.185).Any complication related to the injection procedure including cataract,choroidal and retinal hemorrhage,retinal detachment,or endophthalmitis was not observed in this study.CONCLUSION:The simple and minimally invasive technique of SCS injection of TA with a disposable 30-gauge needle connected to a 1 m L syringe is useful and applicable for macular edema.
文摘To the Editor:While it is only occasionally clinical significance,multiple bilateral iridociliary cysts are commonly encountered.With the cysts progressively growing larger,they may result in vision obstruction, glaucoma,or other ocular problems.[1] Here,we reported an unusual case of multiple ciliary cysts triggering glare with the treatment of neodymium-doped yttrium aluminium garnet (Nd:YAG)laser cystectomy.
