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Mapping quantitative trait loci associated with starch paste viscosity attributes by using double haploid populations of rice (Oryza sativa L.) 被引量:3
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作者 Tahmina SHAR SHENG Zhong-hua +9 位作者 Umed ali Sajid FIAZ WEI Xiang-jin XIE Li-hong JIAO Gui-ai fahad ali SHAO Gao-neng HU Shi-kai HU Pei-song TANG Shao-qing 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2020年第7期1691-1703,共13页
The paste viscosity attributes of starch,measured by rapid visco analyzer(RVA),are important factors for the evaluation of the cooking and eating qualities of rice in breeding programs.To determine the genetic roots o... The paste viscosity attributes of starch,measured by rapid visco analyzer(RVA),are important factors for the evaluation of the cooking and eating qualities of rice in breeding programs.To determine the genetic roots of the paste viscosity attributes of rice grains,quantitative trait loci(QTLs)associated with the paste viscosity attributes were mapped,using a double haploid(DH)population derived from Zhongjiazao 17(YK17),a super rice variety,crossed with D50,a tropic japonica variety.Fifty-four QTLs,for seven parameters of the RVA profiles,were identified in three planting seasons.The 54 QTLs were located on all of the 12 chromosomes,with a single QTL explaining 5.99 to 47.11%of phenotypic variation.From the QTLs identified,four were repeatedly detected under three environmental conditions and the other four QTLs were repeated under two environments.Most of the QTLs detected for peak viscosity(PKV),trough viscosity(TV),cool paste viscosity(CPV),breakdown viscosity(BDV),setback viscosity(SBV),and peak time(PeT)were located in the interval of RM 6775-RM 3805 under all three environmental conditions,with the exception of pasting temperature(PaT).For digenic interactions,eight QTLs with six traits were identified for additivexenvironment interactions in all three planting environments.The epistatic interactions were estimated only for PKV,SBV and PaT.The present study will facilitate further understanding of the genetic architecture of eating and cooking quality(ECQ)in the rice quality improvement program. 展开更多
关键词 RVA profiles eating and cooking quality(ECQ) quantitative trait loci(QTL) DH population RICE
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Protective effect of Genistein against N-nitrosodiethylamine(NDEA)-induced hepatotoxicity in Swiss albino rats 被引量:1
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作者 fahad ali Rahul +2 位作者 Falaq Naz Smita Jyoti Yasir Hasan Siddique 《Journal of Pharmaceutical Analysis》 SCIE CAS 2015年第1期51-57,共7页
In the present study,we studied the effect of Genistein against the hepatotoxicity induced by N-nitrosodiethylamine(NDEA).NDEA is present in almost all kinds of food stuff and has been reported to be a hepatocarcino... In the present study,we studied the effect of Genistein against the hepatotoxicity induced by N-nitrosodiethylamine(NDEA).NDEA is present in almost all kinds of food stuff and has been reported to be a hepatocarcinogen.The male rats were exposed to NDEA(0.1 mg/mL) dissolved in drinking water separately and along with 25,50,100 mg/mL of Genistein for 21 days.The activities of serum glutamic oxaloacetic transaminase(SGOT),serum glutamic pyruvic transaminase(SGPT).alkaline phosphatase(ALP) and lactate dehydrogenase(LDH) were measured in blood serum.Lipid peroxidation,protein carbonyl content,micronucleus frequency and DNA damage(Comet assay) were performed on rat hepatocytes.The results of the study reveal that the treatment of NDEA along with Genistein showed a significant dose-dependent decrease in the levels of blood serum enzymes i.e.,SGOT,SGPT,ALP and LDH(P〈0.05).The HE staining of histological sections of the liver also revealed a protective effect of Genistein.A significant dose-dependent reduction in the lipid peroxidation and protein carbonyl content was observed in rats exposed to NDEA(0.1 mg/mL) along with Genistein(P〈0.05).The results obtained for the comet assay in rat hepatocytes showed a significant dose-dependent decrease in the mean tail length(P〈0.05).Thus the present study supports the hepatoprotective role of Genistein. 展开更多
关键词 Genistein N-nitrosodiethylamine Serum enzymes Antigenotoxic Hepatoprotective
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Tailoring microstructure and mechanical properties of aluminum matrix composites reinforced with novel Al/CuFe multi-layered core-shell particles
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作者 Rashid ali fahad ali +6 位作者 Aqib ZAHOOR Rub Nawaz SHAHID Naeem ul Haq TARIQ Zafar IQBAL Adnan Qayyum BUTT Saad ULLAH Hasan Bin AWAIS 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2022年第6期1822-1833,共12页
Aluminum matrix composites(AMCs), reinforced with novel pre-synthesized Al/Cu Fe multi-layered coreshell particles, were fabricated by different consolidation techniques to investigate their effect on microstructure a... Aluminum matrix composites(AMCs), reinforced with novel pre-synthesized Al/Cu Fe multi-layered coreshell particles, were fabricated by different consolidation techniques to investigate their effect on microstructure and mechanical properties. To synthesize multi-layered Al/Cu Fe core-shell particles, Cu and Fe layers were deposited on Al powder particles by galvanic replacement and electroless plating method, respectively. The core-shell powder and sintered compacts were characterized by using X-ray diffraction(XRD), scanning electron microscopy(SEM) equipped with energy dispersive spectroscopy(EDX), pycnometer, microhardness and compression tests. The results revealed that a higher extent of interfacial reactions, due to the transformation of the deposited layer into intermetallic phases in spark plasma sintered composite, resulted in high relative density(99.26%), microhardness(165 HV0.3) and strength(572 MPa). Further, the presence of un-transformed Cu in the shell structure of hot-pressed composite resulted in the highest fracture strain(20.4%). The obtained results provide stronger implications for tailoring the microstructure of AMCs through selecting appropriate sintering paths to control mechanical properties. 展开更多
关键词 core-shell reinforcement aluminum matrix composites electroless plating sintering techniques spark plasma sintering interfacial reaction
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Use of carbon dioxide as an intravascular contrast agent:A review of current literature
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作者 fahad ali Muhammad Asif Mangi +1 位作者 Hiba Rehman Edo Kaluski 《World Journal of Cardiology》 CAS 2017年第9期715-722,共8页
Use of X-ray contrast allows us to differentiate between two or more adjacent structures on radiographic studies. The X-ray contrast agent can be the one with increase X-ray absorption, like iodine and a barium X-ray ... Use of X-ray contrast allows us to differentiate between two or more adjacent structures on radiographic studies. The X-ray contrast agent can be the one with increase X-ray absorption, like iodine and a barium X-ray contrast agent or the one with decrease X-ray absorption like air and carbon dioxide contrast agent. Each contrast agent possesses different risks and benefits in various ways. Carbon dioxide as an intravascular contrast agent can be used as an alternative intravascular contrast agent and has superior results in some cases. In patients with renal dysfunction or iodinated contrast allergy, the use of Iodinated Contrast Agent poses the risk of considerable morbidity. Similarly, use of Gadolinium is discouraged in subject with severe renal dysfunction. Use of carbon dioxide(CO_2) as an intravascular contrast, offers an alternative in such patients for certain procedures, as it is not nephrotoxic and it does not incite allergic reactions. It is inexpensive, readily available and due to its unique physical properties, it can be used to image a wide variety of vascular beds and chambers. The aim of this paper is to systemically review the current literature to describe the indications, contraindications, adverse effects, instruments, precautions, latest methodologies and data supporting for the use of CO_2 as a contrast agent. 展开更多
关键词 Iodinated Carbon dioxide CONTRAST VASCULAR GADOLINIUM
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Protective effect of capsaicin against methyl methanesulphonate induced toxicity in the third instar larvae of transgenic Drosophila melanogaster(hsp70-lacZ)Bg9 被引量:1
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作者 Saba Khanam Ambreen Fatima +4 位作者 Rahul Smita Jyoti fahad ali Falaq Naz Barkha Shakya Yasir Hasan Siddique 《Chinese Journal of Natural Medicines》 SCIE CAS CSCD 2017年第4期271-280,共10页
Capsaicin(trans-8-methyl-N-vanillyl-6-nonenamide) is the main component in hot peppers, including red chili peppers, alapenos, and habanero, belonging to the genus Capsicum. Capsaicin is a potent antioxidant that inte... Capsaicin(trans-8-methyl-N-vanillyl-6-nonenamide) is the main component in hot peppers, including red chili peppers, alapenos, and habanero, belonging to the genus Capsicum. Capsaicin is a potent antioxidant that interferes with free radical activities. In the present study, the possible protective effect of capsaicin was studied against methyl methanesulphonate(MMS) induced toxicity in third instar larvae of transgenic Drosophila melanogaster(hsp70-lacZ)Bg^9. The third instar was allowed to feed on the diet having different doses of capsaicin and MMS separately and in combination. The results suggested that the exposure of third instar larvae to the diet having MMS alone showed significant hsp70 expression as well as tissue DNA and oxidative damage, whereas the larvae feed on the diet having MMS and capsaicin showed a decrease in the toxic effects for 48-h of exposure. In conclusion, capsaicin showed a dose-dependent decrease in the toxic effects induced by MMS in the third instar larvae of transgenic Drosophila melanogaster. 展开更多
关键词 CAPSAICIN Methyl methanesulphonate Drosophila melanogaster TOXICITY
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Geochemical investigation of low latitude black shale intervals of the Lower to Middle Jurassic succession, Indus Basin, Pakistan
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作者 fahad ali Shiqi ZHANG +7 位作者 Muhammad HANIF Mohibullah MOHIBULLAH Yaxuan ZHANG Muhammad USMAN Sheng WANG Xueliang LIU Pengjie MA Dongmou HUANG 《Frontiers of Earth Science》 SCIE CSCD 2022年第3期568-586,共19页
The Lower to Middle Jurassic sedimentary succession is dominated by siliciclastics with a significant amount of black shales in the Indus Basin,Pakistan.Several outcrop samples have been studied using an integrated ap... The Lower to Middle Jurassic sedimentary succession is dominated by siliciclastics with a significant amount of black shales in the Indus Basin,Pakistan.Several outcrop samples have been studied using an integrated approach to interpret the conceptual depositional setting from carbon and oxygen isotopes(δ^(13)C&δ18O),organic geochemistry,and palynofacies with major and trace element analysis.For interpretation of trace element data,various single and elemental ratios have been used in this research to unlock the geological history of the studied strata.Ti/Al is 1.96 for high-potential source rock and 7.82 for non-potential source rock,and Cr(less than 1)indicates low clastic input with low oxygen for stratified and stagnant water.The ratios of V/(V+Cr),V/(V+Ni),V/Mo,V/Ni,(Cu+Mo)/Zn,Mo/Al,isotopic values ofδ^(13)C andδ18O and besides the V/Cr elemental ratio,all proxies indicate that there are oxygen-depleted anoxic conditions at high potentials,while in non-potential source rock,these ratios show oxic to sub-oxic settings.In addition to the trace element correlation with total organic carbon,the influx of organic matter is determined by the palynoafacies analysis,which indicates mixed terrestrial and marine organic influx in high-potential source rock and vice versa.Furthermore,the studies of palynofaceis DFPF A-D and SFPF A-B suggest that the depositional setting of black shale occurred in the anoxic proximal to distal shelf.The results suggest that the regional and local occurrence of black shale during the Lower to Middle Jurassic and its geological condition were addressed,and these play an important role in its depositional and paleooceanographic setting in the Eastern Tethys. 展开更多
关键词 black shale JURASSIC trace elements organic matter Indus Basin Pakistan
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