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Tagetes erecta Linn.and its mosquitocidal potency against Culex quinquefasciatus 被引量:10
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作者 farjana nikkon M Rowshanul Habib +1 位作者 Zahangir Alam Saud M Rezaul Karim 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2011年第3期186-188,共3页
Objective:To investigate mosquitocidal effects of ethanolic extract of(lowers of Tagetes erecta(T.erecta) and its chloroform and petroleum ether soluble fractions against the larvae of Culex quinquefasciatus(Cx.quinqu... Objective:To investigate mosquitocidal effects of ethanolic extract of(lowers of Tagetes erecta(T.erecta) and its chloroform and petroleum ether soluble fractions against the larvae of Culex quinquefasciatus(Cx.quinquefasciatus).Methods:The fresh flowers of T.erecta were extracted in cold with ethanol(5.0 L) and after concentration,the ethanol extract was fractionated with chloroform and petroleum ether to afford a brownish syrupy suspension of ethanol extract(50.0 g),petroleum ether soluble fraction(18.6 g) and chloroform soluble fraction(23.8 g).The larvicidal effect of ethanol extract and their solvent fractions were determined by the standard procedure of WHO against different instars of Cx.quinquefasciatus.Results:Among the tested samples the chloroform soluble fractions showed the highest toxicity and consequently,the lowest LC_(50) values(14.14 μ g/mL,17.06 μ g/mL.36.88 μ g/mL and 75.48 μ g/mL) for all the instars larvae of Cx.quinquefasciatus.The larvae showed comparative tolerance in the course of increasing age and time.Conclusions:It can be concluded that the flowers of T.erecta are very effective natural larvicide and could be useful against Cx.quinquefasciatus. 展开更多
关键词 TAGETES ERECTA Linn. CULEX quinquefasciatus Say Mosquitocidal Larvae LARVICIDAL effect Toxicity
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Antimicrobial activities of the rhizome extract of Zingiber zerumbet Linn 被引量:4
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作者 Golam Kader farjana nikkon +1 位作者 Mohammad Abdur Rashid Tanzima Yeasmin 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2011年第5期409-412,共4页
Objective:To investigate antimicrobial effects of ethanolic extract of Zingiber zerumbet(Z.zerumbet)(L.)Smith and its chloroform and petroleum ether soluble fractions against pathogenic bacteria and fungi.Methods:The ... Objective:To investigate antimicrobial effects of ethanolic extract of Zingiber zerumbet(Z.zerumbet)(L.)Smith and its chloroform and petroleum ether soluble fractions against pathogenic bacteria and fungi.Methods:The fresh rhizomes of Zingiber zerumbet were extracted in cold with ethanol(4.0 L)after concentration.The crude ethanol extract was fractionated by petroleum ether and chloroform to form a suspension of ethanol extract(15.0 g),petroleum ether fraction(6.6 g)and chloroform soluble fraction(5.0 g).The crude ethanol extract and its petroleum ether and chloroform fractions were evaluated for antibacterial and antifungal activity against thirteen pathogenic bacteria and three fungi by the disc diffusion method.Commercially available kanamycin(30μg/disc)was used as standard disc and blank discs impregnated with the respective solvents were used as negative control.Results:At a concentration of 400μg/disc,all the samples showed mild to moderate antibacterial and antifungal activity and produced the zone of inhibition ranging from 6 mm to 10 mm.Among the tested samples,the crude ethanol extract showed the highest activity against Vibrio parahemolyticus(V.parahemolyticus).The minimum inhibitory concentration(MIC)of the crude ethanol extract and its fractions were within the value of 128-256μg/mL against two Gram positive and four Gram negative bacteria and all the samples showed the lowest MIC value against V.parahemolyticus(128μg/mL).Conclusions:It can be concluded that,potent antibacterial and antifungal phytochemicals are present in ethanol extract of Z.zerumbet(L.). 展开更多
关键词 Zingiberzerumbet(L.) Smith Antibacterial ANTIFUNGAL Minimum inhibitory concentration(MIC) Antimicrobial ACTIVITY RHIZOME ANTIFUNGAL ACTIVITY PHYTOCHEMICALS Disc diffusion method Soluble fraction PATHOGENIC bacteria
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Cytotoxicity of the rhizome of medicinal plants 被引量:1
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作者 Shakhawoat Hossain Golam Kader +1 位作者 farjana nikkon Tanzima Yeasmin 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2012年第2期125-127,共3页
Objective:To investigate the cytotoxicity of the crude ethanol extract of the rhizome of Zingiber zerumbel(Z.zerumbet)(L)Smith,and Curcuma zedoaria(C.zedoaria)Rosc,against Artemia salina Leach.Methods:Fresh rhizomes o... Objective:To investigate the cytotoxicity of the crude ethanol extract of the rhizome of Zingiber zerumbel(Z.zerumbet)(L)Smith,and Curcuma zedoaria(C.zedoaria)Rosc,against Artemia salina Leach.Methods:Fresh rhizomes of Z.zerumbet(L)Smith,and C.zedoaria Rose,were extracted separately in cold with ethanol(2.5 L)and after concentration a brownish syrupy suspension of ethanol extracts of Z.zerumbel(L)Smith,and C.zedoaria Rose,was obtained.The cytotoxic effect of the crude ethanol extracts of both plants was determined by brine shrimp lethality bioassay.Results:Crude ethanol extracts of the rhizome of Z.zerumbel(L)Smith,showed the highest cytotoxicity(LC_(50)was 1.24μg/mL)against brine shrimp nauplii as compared with C.zedoaria Rose.(LC_(50)was 33.593μg/mL)after 24 h of exposure.Conclusions:It can be concluded that the rhizome of Z.zerumbet(|L)Smith,and C.zedoaria Rose,can be used as a source of cytotoxic agent. 展开更多
关键词 CYTOTOXICITY ZINGIBER zerumbet CURCUMA zedoaria BANGLADESH
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Ameliorating effects of Raphanus sativus leaves on sodium arsenite-induced perturbation of blood indices in Swiss albino mice
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作者 Sayada Dilruba MMHasibuzzaman +8 位作者 Mashiur Rahman Nayan Chandra Mohanto Sharmin Aktar Atiqur Rahman Md Imam Hossain Abu Shadat Mohammod Noman farjana nikkon Zahangir Alam Saud Khaled Hossain 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2017年第10期915-920,共7页
Objective: To evaluate the ameliorating effects of Raphanus sativus leaves(RSL)against sodium arsenite(Sa)-induced adverse effects through mice experiments.Methods: Swiss albino mice were divided into four equal group... Objective: To evaluate the ameliorating effects of Raphanus sativus leaves(RSL)against sodium arsenite(Sa)-induced adverse effects through mice experiments.Methods: Swiss albino mice were divided into four equal groups: control, Sa, RSL,RSL + Sa. Sa(10 mg/kg body weight/day), and powder form of RSL(50 mg/kg body weight/day) were provided as food supplement orallty. Blood indices were measured using commercially available kits through colorimetric methods.Results: It was observed that lactate dehydrogenase, alkaline phosphatase, alanine aminotransferase, and aspartate aminotransferase activities were significantly(P < 0.05)higher in Sa-treated mice than those in the control group. RSL significantly reduced Sainduced elevation of the activities of these enzymes in serum significantly(P < 0.05).Serum butyrylcholinesterase activity and high density lipoproteins cholesterol levels in Satreated mice were significantly(P < 0.05) lower than the control group, and the food supplementation of RSL could significantly(P < 0.05) prevent the reduction of Sa-mediated serum butyryl cholinesterase activity and high density lipoproteins cholesterol levels. RSL could also reduce the Sa-induced elevation of serum urea level significantly(P < 0.05).Conclusions: Results of this study suggest the protective or ameliorating effects of RSL on Sa-induced perturbation of blood indices are related to the hepatic, cardiovascular and kidney dysfunction. Therefore, RSL may be useful to reduce arsenic toxicity in human in the future. 展开更多
关键词 Sodium arsenite Raphanus sativus leaves Ameliorating effect Serum indices
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In vivo analysis of toxic effect of hydrose used in food preparations in Bangladesh
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作者 Tuhin Reza Sharmin Aktar +10 位作者 Hasan Al Amin Mashiur Rahman Afroza Arefin Nayan Chandra Mohanto Shahnur Alam Abdullah Al Mamun Anwar Habib Asafudullah farjana nikkon Khaled Hossain Zahangir Alam Saud 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2014年第11期884-889,共6页
Objective:To evaluate the toxic effect of hydrose used in the molasses preparation in Bangladesh.Methods:Molasses were collected from open markets in different parts of Bangladesh.The presence of hydrose in selected m... Objective:To evaluate the toxic effect of hydrose used in the molasses preparation in Bangladesh.Methods:Molasses were collected from open markets in different parts of Bangladesh.The presence of hydrose in selected molasses was detected using commercial kit.To evaluate the toxic effect of hydrose.Swiss albino male mice were divided into four groups.Group Ⅰ was used as control,while Groups Ⅱ,Ⅲ and Ⅳ received hydrose mixing food(5.10 and 25 g/kg food),respectively,and these supplementations were continued to the end of the study(16weeks).Blood was collected from thoracic arteries of the mice under ether anesthesia and then organs were taken.To determine the effect of hydrose on host,blood indices related to liver,heart and kidney dysfunctions were measured.Result:Creatinine and urea levels were significantly(P<0.05) increased in a dose dependent manner in hydrose treated mice,whereas calcium level was significantly decreased in hydrose exposed mice compared to control mice.Histological study of kidney showed the glomeruler inflammation,increased diameter of renal glomeruli and enlargement of proximal tubular lumen of kidneys of mice exposed to hydrose compared to that of control animals.Conclusion:The results of this study indicated that use of hydrose in molasses and other food preparations in Bangladesh may cause kidney impairment. 展开更多
关键词 Hydrose MOLASSES SERUM indices
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