Objective:To explore the application value of color Doppler ultrasound in the detection of hemodynamic change in patients with chronic kidney disease (CKD). Methods:A total of 720 patients with CKD who were admitted i...Objective:To explore the application value of color Doppler ultrasound in the detection of hemodynamic change in patients with chronic kidney disease (CKD). Methods:A total of 720 patients with CKD who were admitted in our hospital from June, 2014 to May, 2016 were included in the study and divided into CKD2 group (n=242), CKD3 group (n=230), and CKD4 group (n=248) according to K/DOQI guideline. Meanwhile, 100 healthy volunteers were served as the control group. The renal parenchymal thickness, length, width, thickness, and hemodynamics by the two-dimensional ultrasound and color Doppler ultrasound in the four groups were observed. Results:The renal parenchymal thickness, length, width, and thickness in CKD2 group were reduced when compared with the control group, but the difference was not statistically significant (P>0.05);the above indicators in CKD3 group were significantly lower than those in the control group and CKD2 group (P<0.001);and the comparison of the above indicators between CKD4 group and other three groups was statistically significant (P<0.001). The comparison of hemodynamic parameters between CKD2 group and the control group was not statistically significant (P>0.05). The various hemodynamic parameters of Vs and Vd in CKD3 group were significantly lower than those in the control group and CKD2 group (P<0.001), while the various indicators of RI were significantly higher than those in the control group and CKD2 group (P<0.001). The various hemodynamic parameters of Vs and Vd in CKD4 group were significantly lower than those in the other three groups (P<0.001), while the various indicators of RI were significantly higher than those in the other three groups (P<0.001). Conclusions:Application of color Doppler ultrasound in detection of the hemodynamic change in patients with CKD can provide a reliable evidence for the disease diagnosis, condition monitoring, and prognosis evaluation, with an important application value.展开更多
文摘Objective:To explore the application value of color Doppler ultrasound in the detection of hemodynamic change in patients with chronic kidney disease (CKD). Methods:A total of 720 patients with CKD who were admitted in our hospital from June, 2014 to May, 2016 were included in the study and divided into CKD2 group (n=242), CKD3 group (n=230), and CKD4 group (n=248) according to K/DOQI guideline. Meanwhile, 100 healthy volunteers were served as the control group. The renal parenchymal thickness, length, width, thickness, and hemodynamics by the two-dimensional ultrasound and color Doppler ultrasound in the four groups were observed. Results:The renal parenchymal thickness, length, width, and thickness in CKD2 group were reduced when compared with the control group, but the difference was not statistically significant (P>0.05);the above indicators in CKD3 group were significantly lower than those in the control group and CKD2 group (P<0.001);and the comparison of the above indicators between CKD4 group and other three groups was statistically significant (P<0.001). The comparison of hemodynamic parameters between CKD2 group and the control group was not statistically significant (P>0.05). The various hemodynamic parameters of Vs and Vd in CKD3 group were significantly lower than those in the control group and CKD2 group (P<0.001), while the various indicators of RI were significantly higher than those in the control group and CKD2 group (P<0.001). The various hemodynamic parameters of Vs and Vd in CKD4 group were significantly lower than those in the other three groups (P<0.001), while the various indicators of RI were significantly higher than those in the other three groups (P<0.001). Conclusions:Application of color Doppler ultrasound in detection of the hemodynamic change in patients with CKD can provide a reliable evidence for the disease diagnosis, condition monitoring, and prognosis evaluation, with an important application value.