BACKGROUND Ectopic pancreas may be unfamiliar to many people because it is rare and difficult to diagnose.However,this disease is highly susceptible to misdiagnosis and missed diagnosis.In this article,we report two c...BACKGROUND Ectopic pancreas may be unfamiliar to many people because it is rare and difficult to diagnose.However,this disease is highly susceptible to misdiagnosis and missed diagnosis.In this article,we report two cases of pancreatic heterotopia in the gastric sinus and small intestine,respectively,both of which were confirmed by histopathological examination.CASE SUMMARY The first patient was a 43-year-old female which reported abdominal distension for 2 mo.The second was a 67-year-old female who experienced intermittent epigastric discomfort for 15 d.In both cases,there was no confirmed preoperative examination,and the postoperative pathology indicated the presence of ectopic pancreas.CONCLUSION The diagnosis of ectopic pancreas is difficult,and is often prone to misdiagnosis and the possibility of being overlooked.Various laboratory tests and imaging tests should be carefully evaluated before surgery to achieve early detection,early diagnosis and early treatment.展开更多
Based on the s-process nucleosynthesis model with the 13C(α,n)16O reaction oc- curring under radiative conditions in the interpulse phases, we investigate the characteristics of the distribution of neutron exposure i...Based on the s-process nucleosynthesis model with the 13C(α,n)16O reaction oc- curring under radiative conditions in the interpulse phases, we investigate the characteristics of the distribution of neutron exposure in low-mass Asymptotic Giant Branch (AGB) stars. We introduce a new concept, the distribution of neutron exposures of the Galaxy (NEG), to study the chemical evolution characteristics of the Galaxy for s-process elements. Using a chemical evolution model of the Galaxy, we develop a model for the NEG and obtain the evolution results of the NEG in different epochs. The present results appear to reasonably re- produce the distribution of neutron exposures of the solar system (hereafter NES). The main component and the strong component in the NES are built up in different epochs. The strong component of the s-process is mainly synthesised in the low-mass and metal-poor AGB stars, and the main component is produced by the s-process in the low-mass AGB stars with higher metallicities.展开更多
分别将SKBR-3细胞接种的32只裸鼠和4T1细胞接种的24只裸鼠随机按1:1:1:1比例分配到对照组,西黄组,5-FU组及西黄与5-FU合用组中。对照组予生理盐水(30mg/kg/3天)腹腔内注射,5-FU组予5-FU(30mg/kg/3天)腹腔内注射,西黄组予西黄胶囊中0.25g...分别将SKBR-3细胞接种的32只裸鼠和4T1细胞接种的24只裸鼠随机按1:1:1:1比例分配到对照组,西黄组,5-FU组及西黄与5-FU合用组中。对照组予生理盐水(30mg/kg/3天)腹腔内注射,5-FU组予5-FU(30mg/kg/3天)腹腔内注射,西黄组予西黄胶囊中0.25g/kg/天灌胃,合用组按照与上述相同的方案用5-FU和西黄治疗。分别测量肿瘤体积,肿瘤重量,裸鼠器官指数和体重的变化,并通过免疫组织化学测定检查PCNA和波形蛋白表达。结果表明,与对照组相比,西黄组,5-FU组和合用组肿瘤体积明显较小,瘤重明显减轻(P<0.05)。在SKBR-3细胞异种移植肿瘤实验中,合用组肿瘤抑制率达38.7%。与对照组相比,5-FU组具有较低的肝脏指数(43.02±5.00mg/g VS 50.95±4.59mg/g),而合用组可以逆转这种现象,肝脏指数为49.69±4.81 mg/g。且合用组的脾指数高于对照组和5-FU组(P<0.05)。在4T1细胞异种移植肿瘤实验中,5-FU组和合用组的肝指数较低(47.69±6.41,49.87±5.96 VS 58.95±7.33),但西黄胶囊组肝脏指数与对照组相比没有显著性差异。在SKBR-3细胞异种移植肿瘤实验中,西黄胶囊组的PCNA和波形蛋白表达显着低于对照组。结果提示西黄胶囊可以抑制裸鼠体内乳腺肿瘤生长,并且能改善移植瘤裸鼠的一般状况和自身免疫。展开更多
A ruthenium complex with a tetradentate bipyridine ligand was proved to be a highly efficient catalyst for the conversions of CO2. Turnovernumbers up to 300000, 9800, and 2100 were achieved for the hydrogenations of C...A ruthenium complex with a tetradentate bipyridine ligand was proved to be a highly efficient catalyst for the conversions of CO2. Turnovernumbers up to 300000, 9800, and 2100 were achieved for the hydrogenations of CO2 to formamides, formamides to methanol and amines, and the directhydrogenation of CO2 to methanol, respectively.展开更多
文摘BACKGROUND Ectopic pancreas may be unfamiliar to many people because it is rare and difficult to diagnose.However,this disease is highly susceptible to misdiagnosis and missed diagnosis.In this article,we report two cases of pancreatic heterotopia in the gastric sinus and small intestine,respectively,both of which were confirmed by histopathological examination.CASE SUMMARY The first patient was a 43-year-old female which reported abdominal distension for 2 mo.The second was a 67-year-old female who experienced intermittent epigastric discomfort for 15 d.In both cases,there was no confirmed preoperative examination,and the postoperative pathology indicated the presence of ectopic pancreas.CONCLUSION The diagnosis of ectopic pancreas is difficult,and is often prone to misdiagnosis and the possibility of being overlooked.Various laboratory tests and imaging tests should be carefully evaluated before surgery to achieve early detection,early diagnosis and early treatment.
基金Supported by the National Natural Science Foundation of China.
文摘Based on the s-process nucleosynthesis model with the 13C(α,n)16O reaction oc- curring under radiative conditions in the interpulse phases, we investigate the characteristics of the distribution of neutron exposure in low-mass Asymptotic Giant Branch (AGB) stars. We introduce a new concept, the distribution of neutron exposures of the Galaxy (NEG), to study the chemical evolution characteristics of the Galaxy for s-process elements. Using a chemical evolution model of the Galaxy, we develop a model for the NEG and obtain the evolution results of the NEG in different epochs. The present results appear to reasonably re- produce the distribution of neutron exposures of the solar system (hereafter NES). The main component and the strong component in the NES are built up in different epochs. The strong component of the s-process is mainly synthesised in the low-mass and metal-poor AGB stars, and the main component is produced by the s-process in the low-mass AGB stars with higher metallicities.
文摘分别将SKBR-3细胞接种的32只裸鼠和4T1细胞接种的24只裸鼠随机按1:1:1:1比例分配到对照组,西黄组,5-FU组及西黄与5-FU合用组中。对照组予生理盐水(30mg/kg/3天)腹腔内注射,5-FU组予5-FU(30mg/kg/3天)腹腔内注射,西黄组予西黄胶囊中0.25g/kg/天灌胃,合用组按照与上述相同的方案用5-FU和西黄治疗。分别测量肿瘤体积,肿瘤重量,裸鼠器官指数和体重的变化,并通过免疫组织化学测定检查PCNA和波形蛋白表达。结果表明,与对照组相比,西黄组,5-FU组和合用组肿瘤体积明显较小,瘤重明显减轻(P<0.05)。在SKBR-3细胞异种移植肿瘤实验中,合用组肿瘤抑制率达38.7%。与对照组相比,5-FU组具有较低的肝脏指数(43.02±5.00mg/g VS 50.95±4.59mg/g),而合用组可以逆转这种现象,肝脏指数为49.69±4.81 mg/g。且合用组的脾指数高于对照组和5-FU组(P<0.05)。在4T1细胞异种移植肿瘤实验中,5-FU组和合用组的肝指数较低(47.69±6.41,49.87±5.96 VS 58.95±7.33),但西黄胶囊组肝脏指数与对照组相比没有显著性差异。在SKBR-3细胞异种移植肿瘤实验中,西黄胶囊组的PCNA和波形蛋白表达显着低于对照组。结果提示西黄胶囊可以抑制裸鼠体内乳腺肿瘤生长,并且能改善移植瘤裸鼠的一般状况和自身免疫。
基金We thank the National Natural Science Foundation of China (Nos. 21790332, 21532003) and the "111" project (B06005) of the Ministry of Education of China for financial support.
文摘A ruthenium complex with a tetradentate bipyridine ligand was proved to be a highly efficient catalyst for the conversions of CO2. Turnovernumbers up to 300000, 9800, and 2100 were achieved for the hydrogenations of CO2 to formamides, formamides to methanol and amines, and the directhydrogenation of CO2 to methanol, respectively.