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Postmenopausal Osteoporosis and Osteopenia Management with a Combination of Once-Monthly Oral Ibandronate and Cholecalciferol—A Systematic Review
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作者 Mauro Geller Mendel Suchmacher +4 位作者 Marcio Cohen Spyros G. E. Mezitis flavia wajnsztajn-theil Karin G. Cunha Rafael Nigri 《International Journal of Clinical Medicine》 CAS 2023年第1期34-57,共24页
Postmenopausal osteoporosis and osteopenia are chronic and uncurable conditions that invariably lead to an increased risk of vertebral, hip, and femoral neck fracture if left untreated. Clinical guidelines establish, ... Postmenopausal osteoporosis and osteopenia are chronic and uncurable conditions that invariably lead to an increased risk of vertebral, hip, and femoral neck fracture if left untreated. Clinical guidelines establish, in general, pharmacological combinations allied to lifestyle changes as the mainstay of their management, and also increasing bone marrow density, lowering fracture risk, and improving quality of life are their main therapeutic goals. The objective of this systematic review was to analyze the available data in the scientific medical literature regarding the role of the ibandronate and cholecalciferol combination in postmenopausal osteoporosis and osteopenia management. Based on our results, we concluded that the above combination is safe and feasible for the clinical control of both conditions. 展开更多
关键词 IBANDRONATE CHOLECALCIFEROL Postmenopausal Osteoporosis Postmenopausal Osteopenia Systematic Review
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