Marine resources have tremendous potential for developing high-value biomaterials.The last decade has seen an increasing number of biomaterials that originate from marine organisms.This field is rapidly evolving.Marin...Marine resources have tremendous potential for developing high-value biomaterials.The last decade has seen an increasing number of biomaterials that originate from marine organisms.This field is rapidly evolving.Marine biomaterials experience several periods of discovery and development ranging from coralline bone graft to polysaccharide-based biomaterials.The latter are represented by chitin and chitosan,marine-derived collagen,and composites of different organisms of marine origin.The diversity of marine natural products,their properties and applications are discussed thoroughly in the present review.These materials are easily available and possess excellent biocompatibility,biodegradability and potent bioactive characteristics.Important applications of marine biomaterials include medical applications,antimicrobial agents,drug delivery agents,anticoagulants,rehabilitation of diseases such as cardiovascular diseases,bone diseases and diabetes,as well as comestible,cosmetic and industrial applications.展开更多
The functional concept of using synthetic entities to supplement or replace certain functions or structures of biological cells is realized by the development of atypical artificial cells using a bottom-up approach.Tr...The functional concept of using synthetic entities to supplement or replace certain functions or structures of biological cells is realized by the development of atypical artificial cells using a bottom-up approach.Tremendous progress has been achieved over the past 5 years that focuses on the therapeutic applications of atypical artificial cells,especially in the anticancer arena.Artificial cell-based anticancer strategies have demon-strated eminent advantages over conventional anticancer tactics,with excellent biocompatibility and targeting capability.The present review commences with introducing the constructing principles and classification of artificial cells.Artificial cell-based applications in cancer prophylaxis,diagnosis,and treatment are subsequently highlighted.These stimulating outcomes may inspire the development of next-generation anticancer ther-apeutic strategies.展开更多
基金This work was supported by the National Natural Science Foundation of China(81722015 and 81870805)the Shaanxi Key Scientific and Technological Innovation Team(2020TD-033)the Innovative research team of high-level local universities in Shanghai and the Oral and maxillofacial regeneration and functional restoration.
文摘Marine resources have tremendous potential for developing high-value biomaterials.The last decade has seen an increasing number of biomaterials that originate from marine organisms.This field is rapidly evolving.Marine biomaterials experience several periods of discovery and development ranging from coralline bone graft to polysaccharide-based biomaterials.The latter are represented by chitin and chitosan,marine-derived collagen,and composites of different organisms of marine origin.The diversity of marine natural products,their properties and applications are discussed thoroughly in the present review.These materials are easily available and possess excellent biocompatibility,biodegradability and potent bioactive characteristics.Important applications of marine biomaterials include medical applications,antimicrobial agents,drug delivery agents,anticoagulants,rehabilitation of diseases such as cardiovascular diseases,bone diseases and diabetes,as well as comestible,cosmetic and industrial applications.
基金National Clinical Research Center for Oral Diseases,Grant/Award Number:LCA202004National Natural Science Foundation of China,Grant/Award Numbers:82301043,82325012Shaanxi Key Scientific and Technological Innovation Team,Grant/Award Number:2020TD-033。
文摘The functional concept of using synthetic entities to supplement or replace certain functions or structures of biological cells is realized by the development of atypical artificial cells using a bottom-up approach.Tremendous progress has been achieved over the past 5 years that focuses on the therapeutic applications of atypical artificial cells,especially in the anticancer arena.Artificial cell-based anticancer strategies have demon-strated eminent advantages over conventional anticancer tactics,with excellent biocompatibility and targeting capability.The present review commences with introducing the constructing principles and classification of artificial cells.Artificial cell-based applications in cancer prophylaxis,diagnosis,and treatment are subsequently highlighted.These stimulating outcomes may inspire the development of next-generation anticancer ther-apeutic strategies.
