Background:Current guidelines for managing pulmonary arterial hypertension(PAH)recommend a risk strati-fication approach.However,the applicability and accuracy of these strategies for PAH associated with congenital he...Background:Current guidelines for managing pulmonary arterial hypertension(PAH)recommend a risk strati-fication approach.However,the applicability and accuracy of these strategies for PAH associated with congenital heart disease(PAH-CHD)require further validation.This study aims to validate the reliability and predictive accuracy of a simplified stratification strategy for PAH-CHD patients over a three-year follow-up.Additionally,new prognostic variables are identified and novel risk stratification methods are developed for assessing and managing PAH-CHD patients.Methods:This retrospective study included 126 PAH-CHD patients.Clinical and biochemical variables across risk groups were assessed using Kruskal-Wallis and Fisher’s exact tests.Indepen-dent risk factors were identified using ordered logistic regression,while Kaplan-Meier and Cox proportional hazards regression analyses evaluated their impact on all-cause mortality.A new stratification model for the PAH-CHD population was constructed based on these analyses.Results:Significant survival differences across stratified risk groups were observed(p<0.001),validating the effectiveness of the simplified risk stratification method in PAH-CHD patients.Prothrombin activity was a strong independent predictor of adverse outcomes of PAH-CHD patients(Hazard ratio 0.95,p<0.001,C-index 0.70).A model combining N-terminal pro-brain natriuretic peptide,prothrombin activity,albumin,and right atrial area achieved an area under the curve of 0.89 and a C-index of 0.85.Conclusions:The simplified risk stratification method is applicable to PAH-CHD patients.Prothrombin activity is a strong independent predictor of adverse outcomes.A comprehensive risk stratification approach,incorporating both established and novel biomarkers,enhances accessibility and offers predictive efficacy during follow-up for PAH-CHD patients,comparable to established models.展开更多
This paper focuses on the application of interactive media technology in the visual interpretation of traditional graphic urban public spaces in China.Case studies and practical exploration show that interactive media...This paper focuses on the application of interactive media technology in the visual interpretation of traditional graphic urban public spaces in China.Case studies and practical exploration show that interactive media technologies such as projection mapping,interactive devices,virtual reality technology,etc.,have realized the diversity of traditional graphics display forms in urban public space.The rich interactive experience design enhances the sense of participation and experience of urban citizens and tourists and promotes the visual culture transmission of traditional Chinese graphics.The future urban public space exhibition is destined to continue to deepen the integration of technology and graphics,promote the visual communication of traditional Chinese graphics visual interpretation in urban public space,and promote sustainable innovation in cultural output in urban public space exhibitions around the world.展开更多
Precision plastic lenses often exhibit dimensional deviations due to the thermal expansion of the mold during injection molding.Although this deviation is smaller in micron-sized(1–5μm)lenses,it exceeds the toleranc...Precision plastic lenses often exhibit dimensional deviations due to the thermal expansion of the mold during injection molding.Although this deviation is smaller in micron-sized(1–5μm)lenses,it exceeds the tolerance requirement of such lenses.It is difficult to resolve this dimensional issue by using injection molding parameters(e.g.,melt temperature,injection speed,and hold pressure).In this study,the thermal analysis of a mold was conducted,and it was confirmed that the deviation of lens dimension was caused by the thermal instability and thermal expansion of the mold.Due to the inconsistent heat distribution of the fixed and the movable side of the mold,the position of the location system was displaced approximately 1 to 5μm.In this study,thermal compensation technology for this the mold was investigated.The temperature on both sides of the mold was measured,and mold temperature could be adjusted automatically using a control strategy based on fuzzy theory.During the mold preheating or mass production stage,the temperature on both sides of the mold could be easily adjusted to quickly obtain the required temperature range.The dilatation on both sides of the mold was revised to improve the alignment accuracy of the cavity,and the decenter error of these injection lenses was reduced to 1μm.This technology can markedly improve the production yield and efficiency of plastic products requiring an extremely high dimensional accuracy.展开更多
Ferroptosis has emerged as a potent form of no-apoptotic cell death that offers a promising alternative to avoid the chemoresistance of apoptotic pathways and serves as a vulnerability of cancer.Herein,we have constru...Ferroptosis has emerged as a potent form of no-apoptotic cell death that offers a promising alternative to avoid the chemoresistance of apoptotic pathways and serves as a vulnerability of cancer.Herein,we have constructed a biomimetic self-assembly nano-prodrug system that enables the co-delivery of gefitinib(Gefi),ferrocene(Fc)and dihydroartemisinin(DHA)for the combined therapy of both ferroptosis and apoptosis.In the tumor microenvironment,this nano-prodrug is able to disassemble and trigger drug release under high levels of GSH.Interestingly,the released DHA can downregulate GPX4 level for the enhancement of intracellular ferroptosis from Fc,further executing tumor cell death with concomitant chemotherapy by Gefi.More importantly,this nano-prodrug provides highly homologous targeting ability by coating related cell membranes and exhibits outstanding inhibition of tumor growth and metastasis,as well as no noticeable side-effects during treatments.This simple small molecular self-assembled nano-prodrug provides a new reasonably designed modality for ferroptosis-combined chemotherapy.展开更多
We propose a scheme for high fidelity quantum state transfer from a mechanical oscillator to a distant moving atom. In the scheme, two optical cavities connected by an optical fiber are interacted effectively through ...We propose a scheme for high fidelity quantum state transfer from a mechanical oscillator to a distant moving atom. In the scheme, two optical cavities connected by an optical fiber are interacted effectively through adiabatically eliminating fiber mode under large detuning limit. The quantum state transfer fidelity can be raised asymptotically to 100% by optimizing the Gaussian pulse G(t), the maximum atom-cavity coupling strength Ω<sub>max</sub>, and the atomic velocity v. We also show that the affect of dissipation can be obviously depressed by synchronously increasing Ωmax</sub> and v.展开更多
We report a colloidal process to coat a layer of TiO2onto SiO2composite nanofibers containing embedded CdS and upconversion nanoparticles(UCNPs).The SiO2composite nanofibers were fabricated by electrospinning.To impro...We report a colloidal process to coat a layer of TiO2onto SiO2composite nanofibers containing embedded CdS and upconversion nanoparticles(UCNPs).The SiO2composite nanofibers were fabricated by electrospinning.To improve the energy transfer efficiency,UCNPs and CdS nanoparticles were bound in close proximity to each other within the SiO2matrix.β‐NaYF4:Yb(30%),Tm(0.5%)@NaYF4:Yb(20%),Er(2%)core–shell nanoparticles were used as nanotransducers for near infrared light.These nanoparticles exhibited enhanced upconversion fluorescence compared withβ‐NaYF4:Yb(30%),Tm(0.5%)orβ–NaYF4:Yb(30%),Tm(0.5%)@NaYF4nanoparticles.The morphologies,size and chemical compositions have been extensively investigated using field emission scanning electron microscopy(FESEM),transmission electron microscopy(TEM),X‐ray diffraction(XRD)and X‐ray photoelectron spectra(XPS),respectively.The TEM images showed that the TiO2composite nanotubes were embedded with a large amount of UCNPs and CdS nanoparticles.The composite TiO2nanotubes degraded more than90%of rhodamine B(RhB)dye during20min of irradiation by simulated solar light.In particular,more than50%of RhB was decomposed in70min,under irradiation of near infrared light(NIR).This high degradation was attributed to the full spectrum absorption of solar light,and the enhanced transfer efficiency for near infrared light.The as‐prepared nanostructures can harness solar energy,and provide an alternative to overcome energy shortages and environmental protection.展开更多
Rectal foreign bodies are man-made injury that occurs occasionally.The management depends on its depth and the consequence it caused.We here report a case of rectal foreign body(a glass bottle measuring about 38 mm...Rectal foreign bodies are man-made injury that occurs occasionally.The management depends on its depth and the consequence it caused.We here report a case of rectal foreign body(a glass bottle measuring about 38 mm×75 mm)which was located 13-15 cm from the anus.The patient had no sign of perforation,and we managed to remove it using endoscopy with gastrolith forceps.展开更多
We performed endoscopic submucosal dissection of a gastric fundus tumor.It was difficult to strip the tumor completely due to space limitation,and we used blunt dissection to remove the tumor quickly and safely.Firstl...We performed endoscopic submucosal dissection of a gastric fundus tumor.It was difficult to strip the tumor completely due to space limitation,and we used blunt dissection to remove the tumor quickly and safely.Firstly,the basal area of the 2.5 cm submucosal tumor located in the gastric fundus was cut open,and the mucosa was dissected.The tumor was difficult to peel,therefore,a snare was used and the tumor was pulled and tightened slightly.Short electronic coagulation was used during the procedure.The tumor was then bluntly dissected.This method ensured rapid and complete removal of the tumor.展开更多
The nonradiative recombination of charge carriers at the hole transport layer(HTL)/perovskite interface generally induces remarkable performance loss of the inverted two-dimensional perovskite solar cells(2D PSCs). He...The nonradiative recombination of charge carriers at the hole transport layer(HTL)/perovskite interface generally induces remarkable performance loss of the inverted two-dimensional perovskite solar cells(2D PSCs). Herein, a cross-linkable small molecule of 2-mercaptoimidazole(2-MI) was introduced into the nickel oxide(NiO_(x))/2D perovskite interface. Experiments have confirmed the formation of Ni-N covalent bond by N atom in the 2-MI and Ni in the NiO_(x) and the coordinating between S atom of 2-MI and under-coordinated Pb^(2+) near to the NiO_(x)/perovskite interface, which contributes to creating a crosslinking between NiO_(x)/perovskite interface to restrain charge carrier recombination and enhance the extraction of hole carriers at the interface. Besides, the 2-MI modification layer is also beneficial for promoting the crystallinity of 2D perovskite. Consequently, the inverted 2D PSCs with 2-MI modification achieved the best power conversion efficiency of 15%. This paves a route to acquire highly efficient 2D PSCs by constructing a cross-linking at the NiO_(x)HTL/2D perovskite interface.展开更多
A projectile with exotic wraparound wings( WAW) configuration is designed to improve the finstabilized projectile shooting quality. Two fin-stabilized projectiles with the same body with and without exotic WAW configu...A projectile with exotic wraparound wings( WAW) configuration is designed to improve the finstabilized projectile shooting quality. Two fin-stabilized projectiles with the same body with and without exotic WAW configuration are simulated numerically by applying the Roe scheme. The shear-stress transport turbulence models and the lower-upper symmetric Gauss-Seidel implicit method are used to solve 3D Reynoldsaveraged Navier—Stokes equations. The differences in aerodynamic coefficients and aerodynamic characteristics of the projectiles when the Mach number varies from 0. 35 to 0. 95 are obtained,and the cause of these differences is analyzed. The calculation results indicate that the lift-to-drag ratio of the projectile significantly increases,the rolling moment decreases,and the position of the pressure center of the projectile shows relatively small changes when the exotic WAW configuration is used. Therefore,this projectile can obviously reduce rolling effect,enlarge range and improve flying stability.展开更多
Purpose:The toughest challenge in pedestrian traffic accident identification lies in ascertaining injurymanners.This study aimed to systematically simulate and parameterize 3 types of craniocerebral injuryincluding im...Purpose:The toughest challenge in pedestrian traffic accident identification lies in ascertaining injurymanners.This study aimed to systematically simulate and parameterize 3 types of craniocerebral injuryincluding impact injury,fall injury,and run-over injury,to compare the injury response outcomes ofdifferent injury manners.Methods:Based on the total human model for safety(THUMS)and its enhanced human model THUMShollow structures,a total of 84 simulations with 3 injury manners,different loading directions,andloading velocities were conducted.Von Mises stress,intracranial pressure,maximum principal strain,cumulative strain damage measure,shear stress,and cranial strain were employed to analyze the injuryresponse of all areas of the brain.To examine the association between injury conditions and injuryconsequences,correlation analysis,principal component analysis,linear regression,and stepwise linearregression were utilized.Results:There is a significant correlation observed between each criterion of skull and brain injury(p<0.01 in all Pearson correlation analysis results).A 2-phase increase of cranio-cerebral stress andstrain as impact speed increases.In high-speed impact(>40 km/h),the Von Mises stress on the skull waswith a high possibility exceed the threshold for skull fracture(100 MPa).When falling and makingtemporal and occipital contact with the ground,the opposite side of the impacted area experienceshigher frequency stress concentration than contact at other conditions.Run-over injuries tend to have amore comprehensive craniocerebral injury,with greater overall deformation due to more adequate kinetic energy conduction.The mean value of maximum principal strain of brain and Von Mises stress ofcranium at run-over condition are 1.39 and 403.8 MPa,while they were 1.31,94.11 MPa and 0.64,120.5 MPa for the impact and fall conditions,respectively.The impact velocity also plays a significant rolein craniocerebral injury in impact and fall loading conditions(the p of all F-test<0.05).A regressionequation of the craniocerebral injury manners in pedestrian accidents was established.Conclusion:The study distinguished the craniocerebral injuries caused in different manners,elucidatedthe biomechanical mechanisms of craniocerebral injury,and provided a biomechanical foundation forthe identification of craniocerebral injury in legal contexts.展开更多
As a famous hole transporting material, nickle oxide (NiOx) has drawn enormous attention due to its low cost and superior stability. However, the relatively low conductivity and high-density surface trap states of NiO...As a famous hole transporting material, nickle oxide (NiOx) has drawn enormous attention due to its low cost and superior stability. However, the relatively low conductivity and high-density surface trap states of NiOx severely limit device performance in solar cell applications. Interfacial engineering is an efficient approach to achieve remarkable hole-transporting performance by surface passivation. Herein, the efficient NiOx hole transport layer was prepared by surface passivation engineering strategy via facile solution processes with cesium iodide (CsI). It is demonstrated that CsI plays a super-effective dual-function role in inverted solar cell device: On one hand, the presence of CsI hugely passivates the surface trap states at the NiOx/perovskite interface along with obviously improved conductivity by the incorporated Cs^(+);on the other hand, the ions immigration is significantly suppressed by the presence of I ion for high-quality perovskite films, resulting in a stable contact interface. The ameliorative interface leads to largely reduced carrier non-radiative recombination, attributing to boosted carrier extraction efficiency. As a result, decent power conversion efficiency (PCE) of 18.48% with a noticeable fill factor (FF) beyond 80% was achieved. This facile and efficient surface engineering approach with dual-function shows excellent potential for the design of high-performance functional interfacial modification layer to achieve high-performance solar cells.展开更多
The rapid and accurate detection of cherry tomatoes is of great significance to realizing automatic picking by robots.However,so far,cherry tomatoes are detected as only one class for picking.Fruits occluded by branch...The rapid and accurate detection of cherry tomatoes is of great significance to realizing automatic picking by robots.However,so far,cherry tomatoes are detected as only one class for picking.Fruits occluded by branches or leaves are detected as pickable objects,which may cause damage to the plant or robot end-effector during picking.This study proposed the Feature Enhancement Network Block(FENB)based on YOLOv4-Tiny to solve the above problem.Firstly,according to the distribution characteristics and picking strategies of cherry tomatoes,cherry tomatoes were divided into four classes in the nighttime,and daytime included not occluded,occluded by branches,occluded by fruits,and occluded by leaves.Secondly,the CSPNet structure with the hybrid attention mechanism was used to design the FENB,which pays more attention to the effective features of different classes of cherry tomatoes while retaining the original features.Finally,the Feature Enhancement Network(FEN)was constructed based on the FENB to enhance the feature extraction ability and improve the detection accuracy of YOLOv4-Tiny.The experimental results show that under the confidence of 0.5,average precision(AP)of non-occluded,branch-occluded,fruit-occluded,and leaf-occluded fruit over the day test images were 95.86%,92.59%,89.66%,and 84.99%,respectively,which were 98.43%,95.62%,95.50%,and 89.33% on the night test images,respectively.The mean Average Precision(mAP)of four classes over the night test set was higher(94.72%)than that of the day(90.78%),which were both better than YOLOv4 and YOLOv4-Tiny.It cost 32.22 ms to process a 416×416 image on the GPU.The model size was 39.34 MB.Therefore,the proposed model can provide a practical and feasible method for the multi-class detection of cherry tomatoes.展开更多
Evolution of a two-dimensional air/SF6 single-mode interface is numerically investigated by an upwind CE/SE method under a cylindrically converging circumstance. The Rayleigh-Taylor effect caused by the flow decelerat...Evolution of a two-dimensional air/SF6 single-mode interface is numerically investigated by an upwind CE/SE method under a cylindrically converging circumstance. The Rayleigh-Taylor effect caused by the flow deceleration on the phase inversion(RTPI)is highlighted. The RTPI was firstly observed in our previous experiment, but the related mechanism remains unclear. By isolating the three-dimensional effect, it is found here that the initial amplitude(a0), the azimuthal mode number(k0) and the re-shocking moment are the three major parameters which determine the RTPI occurrence. In the variable space of(k0, a0), a critical a0 for the RTPI occurrence is solved for each k0, and there exists a threshold value of k0 below which the RTPI will not occur no matter what a0 is. There exists a special k0 corresponding to the largest critical a0, and the reduction rule of critical a0 with k0 can be well described by an exponential decay function. The results show that the occurrence of the RTPI requires a small a0 which should be less than a critical value, a large k0 which should exceed a threshold, and a right impinging moment of the re-shock which should be later than the RTPI occurrence. Finally, the effects of the incident shock strength, the density ratio and the initial position of the interface on the threshold value of k0 and on the maximum critical a0 are examined. These new findings would facilitate the understanding of the converging Richtmyer-Meshkov instability and would be helpful for designing an optimal structure of the inertia confinement fusion capsule.展开更多
Background: Accurate estimation of the glomerular filtration rate (GFR) and staging of chronic kidney disease (CKD) are important. Currently, there is no research on the differences in several estimated GFR equations ...Background: Accurate estimation of the glomerular filtration rate (GFR) and staging of chronic kidney disease (CKD) are important. Currently, there is no research on the differences in several estimated GFR equations for staging CKD in a large sample of centenarians. Thus, this study aimed to investigate the differences in CKD staging with the most commonly used equations and to analyze sources of discrepancy. Methods: A total of 966 centenarians were enrolled in this study from June 2014 to December 2016 in Hainan province, China. The GFR with the Modification of Diet in Renal Disease (MDRD), Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) and Berlin Initiative Study 1 (BIS1) equations were estimated. Agreement between these equations was investigated with the k statistic and Bland-Altman plots. Sources of discrepancy were investigated by partial correlation analysis. Results: The k values of the MDRD and CKD-EPI equations, MDRD and BIS1 equations, and CKD-EPI and BIS1 equations were 0.610, 0.253, and 0.381, respectively. Serum creatinine (Scr) explained 10.96%, 41.60% and 17.06% of the variability in these three comparisons, respectively. Serum uric acid (SUA) explained 3.65% and 5.43% of the variability in the first 2 comparisons, respectively. Gender was associated with significant differences in these 3 comparisons (P<0.001). Conclusions: The strengths of agreement between the MDRD and CKD-EPI equations were substantial, but those between the MDRD and BIS 1 equations and the CKD-EPI and BIS 1 equations were fair. The difference in CKD staging of the first 2 comparisons strongly depended on Scr, SUA and gender, and that of CKD-EPI and BIS1 equations strongly depended on Scr and gender. The incidence at various stages of CKD staging was quite different. Thus, a new equation that is more suitable for the elderly needs to be built in the future.展开更多
基金This work was supported by the National Natural Science Foundation of China(82070052)the Joint Funds of the Natural Science Foundation of Gansu Province(23JRRA1544)granted to Yunshan Cao.
文摘Background:Current guidelines for managing pulmonary arterial hypertension(PAH)recommend a risk strati-fication approach.However,the applicability and accuracy of these strategies for PAH associated with congenital heart disease(PAH-CHD)require further validation.This study aims to validate the reliability and predictive accuracy of a simplified stratification strategy for PAH-CHD patients over a three-year follow-up.Additionally,new prognostic variables are identified and novel risk stratification methods are developed for assessing and managing PAH-CHD patients.Methods:This retrospective study included 126 PAH-CHD patients.Clinical and biochemical variables across risk groups were assessed using Kruskal-Wallis and Fisher’s exact tests.Indepen-dent risk factors were identified using ordered logistic regression,while Kaplan-Meier and Cox proportional hazards regression analyses evaluated their impact on all-cause mortality.A new stratification model for the PAH-CHD population was constructed based on these analyses.Results:Significant survival differences across stratified risk groups were observed(p<0.001),validating the effectiveness of the simplified risk stratification method in PAH-CHD patients.Prothrombin activity was a strong independent predictor of adverse outcomes of PAH-CHD patients(Hazard ratio 0.95,p<0.001,C-index 0.70).A model combining N-terminal pro-brain natriuretic peptide,prothrombin activity,albumin,and right atrial area achieved an area under the curve of 0.89 and a C-index of 0.85.Conclusions:The simplified risk stratification method is applicable to PAH-CHD patients.Prothrombin activity is a strong independent predictor of adverse outcomes.A comprehensive risk stratification approach,incorporating both established and novel biomarkers,enhances accessibility and offers predictive efficacy during follow-up for PAH-CHD patients,comparable to established models.
文摘This paper focuses on the application of interactive media technology in the visual interpretation of traditional graphic urban public spaces in China.Case studies and practical exploration show that interactive media technologies such as projection mapping,interactive devices,virtual reality technology,etc.,have realized the diversity of traditional graphics display forms in urban public space.The rich interactive experience design enhances the sense of participation and experience of urban citizens and tourists and promotes the visual culture transmission of traditional Chinese graphics.The future urban public space exhibition is destined to continue to deepen the integration of technology and graphics,promote the visual communication of traditional Chinese graphics visual interpretation in urban public space,and promote sustainable innovation in cultural output in urban public space exhibitions around the world.
文摘Precision plastic lenses often exhibit dimensional deviations due to the thermal expansion of the mold during injection molding.Although this deviation is smaller in micron-sized(1–5μm)lenses,it exceeds the tolerance requirement of such lenses.It is difficult to resolve this dimensional issue by using injection molding parameters(e.g.,melt temperature,injection speed,and hold pressure).In this study,the thermal analysis of a mold was conducted,and it was confirmed that the deviation of lens dimension was caused by the thermal instability and thermal expansion of the mold.Due to the inconsistent heat distribution of the fixed and the movable side of the mold,the position of the location system was displaced approximately 1 to 5μm.In this study,thermal compensation technology for this the mold was investigated.The temperature on both sides of the mold was measured,and mold temperature could be adjusted automatically using a control strategy based on fuzzy theory.During the mold preheating or mass production stage,the temperature on both sides of the mold could be easily adjusted to quickly obtain the required temperature range.The dilatation on both sides of the mold was revised to improve the alignment accuracy of the cavity,and the decenter error of these injection lenses was reduced to 1μm.This technology can markedly improve the production yield and efficiency of plastic products requiring an extremely high dimensional accuracy.
基金financially supported in part by the National Key R&D Program of China (2020YFA0406103)the National Natural Science Foundation of China (21725102, 22122506, 91961106, 22075267, 22109148)+4 种基金Strategic Priority Research Program of the Chinese Academy of Sciences (XDPB14)the Youth Innovation Promotion Association of the Chinese Academy of Sciences (2019444)the Hundred Talents Program of the Chinese Academy of SciencesFundamental Research Funds for the Central Universities (WK2060000039)support from the USTC Center for Micro- and Nanoscale Research and Fabrication。
基金financial supports from National Natural Science Foundation of China(32000992,21977081,32101124)the Zhejiang Provincial Natural Science Foundation for Distinguished Young Scholar(LR23C100001)+1 种基金Wenzhou Medical University(KYYW201901)Zhejiang Qianjiang Talent Plan(QJD20020224)
文摘Ferroptosis has emerged as a potent form of no-apoptotic cell death that offers a promising alternative to avoid the chemoresistance of apoptotic pathways and serves as a vulnerability of cancer.Herein,we have constructed a biomimetic self-assembly nano-prodrug system that enables the co-delivery of gefitinib(Gefi),ferrocene(Fc)and dihydroartemisinin(DHA)for the combined therapy of both ferroptosis and apoptosis.In the tumor microenvironment,this nano-prodrug is able to disassemble and trigger drug release under high levels of GSH.Interestingly,the released DHA can downregulate GPX4 level for the enhancement of intracellular ferroptosis from Fc,further executing tumor cell death with concomitant chemotherapy by Gefi.More importantly,this nano-prodrug provides highly homologous targeting ability by coating related cell membranes and exhibits outstanding inhibition of tumor growth and metastasis,as well as no noticeable side-effects during treatments.This simple small molecular self-assembled nano-prodrug provides a new reasonably designed modality for ferroptosis-combined chemotherapy.
文摘We propose a scheme for high fidelity quantum state transfer from a mechanical oscillator to a distant moving atom. In the scheme, two optical cavities connected by an optical fiber are interacted effectively through adiabatically eliminating fiber mode under large detuning limit. The quantum state transfer fidelity can be raised asymptotically to 100% by optimizing the Gaussian pulse G(t), the maximum atom-cavity coupling strength Ω<sub>max</sub>, and the atomic velocity v. We also show that the affect of dissipation can be obviously depressed by synchronously increasing Ωmax</sub> and v.
基金supported in part by the National Natural Science Foundation of China(21471043,21304028,51403195,31501576)~~
文摘We report a colloidal process to coat a layer of TiO2onto SiO2composite nanofibers containing embedded CdS and upconversion nanoparticles(UCNPs).The SiO2composite nanofibers were fabricated by electrospinning.To improve the energy transfer efficiency,UCNPs and CdS nanoparticles were bound in close proximity to each other within the SiO2matrix.β‐NaYF4:Yb(30%),Tm(0.5%)@NaYF4:Yb(20%),Er(2%)core–shell nanoparticles were used as nanotransducers for near infrared light.These nanoparticles exhibited enhanced upconversion fluorescence compared withβ‐NaYF4:Yb(30%),Tm(0.5%)orβ–NaYF4:Yb(30%),Tm(0.5%)@NaYF4nanoparticles.The morphologies,size and chemical compositions have been extensively investigated using field emission scanning electron microscopy(FESEM),transmission electron microscopy(TEM),X‐ray diffraction(XRD)and X‐ray photoelectron spectra(XPS),respectively.The TEM images showed that the TiO2composite nanotubes were embedded with a large amount of UCNPs and CdS nanoparticles.The composite TiO2nanotubes degraded more than90%of rhodamine B(RhB)dye during20min of irradiation by simulated solar light.In particular,more than50%of RhB was decomposed in70min,under irradiation of near infrared light(NIR).This high degradation was attributed to the full spectrum absorption of solar light,and the enhanced transfer efficiency for near infrared light.The as‐prepared nanostructures can harness solar energy,and provide an alternative to overcome energy shortages and environmental protection.
文摘Rectal foreign bodies are man-made injury that occurs occasionally.The management depends on its depth and the consequence it caused.We here report a case of rectal foreign body(a glass bottle measuring about 38 mm×75 mm)which was located 13-15 cm from the anus.The patient had no sign of perforation,and we managed to remove it using endoscopy with gastrolith forceps.
文摘We performed endoscopic submucosal dissection of a gastric fundus tumor.It was difficult to strip the tumor completely due to space limitation,and we used blunt dissection to remove the tumor quickly and safely.Firstly,the basal area of the 2.5 cm submucosal tumor located in the gastric fundus was cut open,and the mucosa was dissected.The tumor was difficult to peel,therefore,a snare was used and the tumor was pulled and tightened slightly.Short electronic coagulation was used during the procedure.The tumor was then bluntly dissected.This method ensured rapid and complete removal of the tumor.
基金supported by the Sichuan Science and Technology Program (2021YFH0090)。
文摘The nonradiative recombination of charge carriers at the hole transport layer(HTL)/perovskite interface generally induces remarkable performance loss of the inverted two-dimensional perovskite solar cells(2D PSCs). Herein, a cross-linkable small molecule of 2-mercaptoimidazole(2-MI) was introduced into the nickel oxide(NiO_(x))/2D perovskite interface. Experiments have confirmed the formation of Ni-N covalent bond by N atom in the 2-MI and Ni in the NiO_(x) and the coordinating between S atom of 2-MI and under-coordinated Pb^(2+) near to the NiO_(x)/perovskite interface, which contributes to creating a crosslinking between NiO_(x)/perovskite interface to restrain charge carrier recombination and enhance the extraction of hole carriers at the interface. Besides, the 2-MI modification layer is also beneficial for promoting the crystallinity of 2D perovskite. Consequently, the inverted 2D PSCs with 2-MI modification achieved the best power conversion efficiency of 15%. This paves a route to acquire highly efficient 2D PSCs by constructing a cross-linking at the NiO_(x)HTL/2D perovskite interface.
基金Sponsored by the National Natural Science Foundation of China(Grant No.51076066)
文摘A projectile with exotic wraparound wings( WAW) configuration is designed to improve the finstabilized projectile shooting quality. Two fin-stabilized projectiles with the same body with and without exotic WAW configuration are simulated numerically by applying the Roe scheme. The shear-stress transport turbulence models and the lower-upper symmetric Gauss-Seidel implicit method are used to solve 3D Reynoldsaveraged Navier—Stokes equations. The differences in aerodynamic coefficients and aerodynamic characteristics of the projectiles when the Mach number varies from 0. 35 to 0. 95 are obtained,and the cause of these differences is analyzed. The calculation results indicate that the lift-to-drag ratio of the projectile significantly increases,the rolling moment decreases,and the position of the pressure center of the projectile shows relatively small changes when the exotic WAW configuration is used. Therefore,this projectile can obviously reduce rolling effect,enlarge range and improve flying stability.
基金The study was funded by grants from the National Key Researchand Development Plan(2022YFC3302002)the National NaturalScience Foundation of China(82171872)+5 种基金Shanghai Yangfan SpecialProgramme(23YF1448700)Natural Science Foundation ofShanghai(21ZR1464600)the 2023 Open Foundation of Key Laboratory of Forensic Pathology,Ministry of Public Security,P.R.China(GAFYBL202308)Shanghai Key Laboratory of Forensic Medicine(21DZ2270800)Shanghai Forensic Service Platform(19DZ2290900)Central Research Institute Public Project(GY2023Z-3).
文摘Purpose:The toughest challenge in pedestrian traffic accident identification lies in ascertaining injurymanners.This study aimed to systematically simulate and parameterize 3 types of craniocerebral injuryincluding impact injury,fall injury,and run-over injury,to compare the injury response outcomes ofdifferent injury manners.Methods:Based on the total human model for safety(THUMS)and its enhanced human model THUMShollow structures,a total of 84 simulations with 3 injury manners,different loading directions,andloading velocities were conducted.Von Mises stress,intracranial pressure,maximum principal strain,cumulative strain damage measure,shear stress,and cranial strain were employed to analyze the injuryresponse of all areas of the brain.To examine the association between injury conditions and injuryconsequences,correlation analysis,principal component analysis,linear regression,and stepwise linearregression were utilized.Results:There is a significant correlation observed between each criterion of skull and brain injury(p<0.01 in all Pearson correlation analysis results).A 2-phase increase of cranio-cerebral stress andstrain as impact speed increases.In high-speed impact(>40 km/h),the Von Mises stress on the skull waswith a high possibility exceed the threshold for skull fracture(100 MPa).When falling and makingtemporal and occipital contact with the ground,the opposite side of the impacted area experienceshigher frequency stress concentration than contact at other conditions.Run-over injuries tend to have amore comprehensive craniocerebral injury,with greater overall deformation due to more adequate kinetic energy conduction.The mean value of maximum principal strain of brain and Von Mises stress ofcranium at run-over condition are 1.39 and 403.8 MPa,while they were 1.31,94.11 MPa and 0.64,120.5 MPa for the impact and fall conditions,respectively.The impact velocity also plays a significant rolein craniocerebral injury in impact and fall loading conditions(the p of all F-test<0.05).A regressionequation of the craniocerebral injury manners in pedestrian accidents was established.Conclusion:The study distinguished the craniocerebral injuries caused in different manners,elucidatedthe biomechanical mechanisms of craniocerebral injury,and provided a biomechanical foundation forthe identification of craniocerebral injury in legal contexts.
基金This research was supported by the Sichuan Science and Technology Program(No.2021YFH0090)Scientific Research Start-Up Project of Southwest Petroleum University,China(No.X151528)The authors are grateful to the colleagues for their assistance.
文摘As a famous hole transporting material, nickle oxide (NiOx) has drawn enormous attention due to its low cost and superior stability. However, the relatively low conductivity and high-density surface trap states of NiOx severely limit device performance in solar cell applications. Interfacial engineering is an efficient approach to achieve remarkable hole-transporting performance by surface passivation. Herein, the efficient NiOx hole transport layer was prepared by surface passivation engineering strategy via facile solution processes with cesium iodide (CsI). It is demonstrated that CsI plays a super-effective dual-function role in inverted solar cell device: On one hand, the presence of CsI hugely passivates the surface trap states at the NiOx/perovskite interface along with obviously improved conductivity by the incorporated Cs^(+);on the other hand, the ions immigration is significantly suppressed by the presence of I ion for high-quality perovskite films, resulting in a stable contact interface. The ameliorative interface leads to largely reduced carrier non-radiative recombination, attributing to boosted carrier extraction efficiency. As a result, decent power conversion efficiency (PCE) of 18.48% with a noticeable fill factor (FF) beyond 80% was achieved. This facile and efficient surface engineering approach with dual-function shows excellent potential for the design of high-performance functional interfacial modification layer to achieve high-performance solar cells.
基金financially supported by National Natural Science Foundation of China(Grant No.52075149)Frontier Exploration Projects of Longmen Laboratory(Grant No.LMQYTSKT032)+3 种基金Scientific and Technological Project of Henan Province(Grant No.212102110029)High-tech Key Laboratory of Agricultural Equipment and Intelligence of Jiangsu Province(Grant No.JNZ201901)Colleges and Universities of Henan Province Youth Backbone Teacher Training Program(Grant No.2017GGJS062)Postgraduate Education Reform Project of Henan Province(Grant No.2021SJGLX005Y,2019SJGLX063Y).
文摘The rapid and accurate detection of cherry tomatoes is of great significance to realizing automatic picking by robots.However,so far,cherry tomatoes are detected as only one class for picking.Fruits occluded by branches or leaves are detected as pickable objects,which may cause damage to the plant or robot end-effector during picking.This study proposed the Feature Enhancement Network Block(FENB)based on YOLOv4-Tiny to solve the above problem.Firstly,according to the distribution characteristics and picking strategies of cherry tomatoes,cherry tomatoes were divided into four classes in the nighttime,and daytime included not occluded,occluded by branches,occluded by fruits,and occluded by leaves.Secondly,the CSPNet structure with the hybrid attention mechanism was used to design the FENB,which pays more attention to the effective features of different classes of cherry tomatoes while retaining the original features.Finally,the Feature Enhancement Network(FEN)was constructed based on the FENB to enhance the feature extraction ability and improve the detection accuracy of YOLOv4-Tiny.The experimental results show that under the confidence of 0.5,average precision(AP)of non-occluded,branch-occluded,fruit-occluded,and leaf-occluded fruit over the day test images were 95.86%,92.59%,89.66%,and 84.99%,respectively,which were 98.43%,95.62%,95.50%,and 89.33% on the night test images,respectively.The mean Average Precision(mAP)of four classes over the night test set was higher(94.72%)than that of the day(90.78%),which were both better than YOLOv4 and YOLOv4-Tiny.It cost 32.22 ms to process a 416×416 image on the GPU.The model size was 39.34 MB.Therefore,the proposed model can provide a practical and feasible method for the multi-class detection of cherry tomatoes.
基金supported by the National Natural Science Foundation of China(Grant Nos.11772329,11802304,and U1530103)the Science Challenge Project(Grant No.TZ2016001)the Research Grants Council,Hong Kong(Grant No.152151/16E)
文摘Evolution of a two-dimensional air/SF6 single-mode interface is numerically investigated by an upwind CE/SE method under a cylindrically converging circumstance. The Rayleigh-Taylor effect caused by the flow deceleration on the phase inversion(RTPI)is highlighted. The RTPI was firstly observed in our previous experiment, but the related mechanism remains unclear. By isolating the three-dimensional effect, it is found here that the initial amplitude(a0), the azimuthal mode number(k0) and the re-shocking moment are the three major parameters which determine the RTPI occurrence. In the variable space of(k0, a0), a critical a0 for the RTPI occurrence is solved for each k0, and there exists a threshold value of k0 below which the RTPI will not occur no matter what a0 is. There exists a special k0 corresponding to the largest critical a0, and the reduction rule of critical a0 with k0 can be well described by an exponential decay function. The results show that the occurrence of the RTPI requires a small a0 which should be less than a critical value, a large k0 which should exceed a threshold, and a right impinging moment of the re-shock which should be later than the RTPI occurrence. Finally, the effects of the incident shock strength, the density ratio and the initial position of the interface on the threshold value of k0 and on the maximum critical a0 are examined. These new findings would facilitate the understanding of the converging Richtmyer-Meshkov instability and would be helpful for designing an optimal structure of the inertia confinement fusion capsule.
基金National Key R&D Program of China (No.2016YFC1305500)Key Research and Development Program of Hainan (Nos.ZDYF2016135 and ZDYF2017095)+2 种基金the National Natural Science Foundation of China (Nos.61471399,61671479,and 81670663)the National Key Research and Development Program (No. 2016YFC1305404)the Joint Funds of National Natural Science Foundation of China and Henan province (No.U1604284).
文摘Background: Accurate estimation of the glomerular filtration rate (GFR) and staging of chronic kidney disease (CKD) are important. Currently, there is no research on the differences in several estimated GFR equations for staging CKD in a large sample of centenarians. Thus, this study aimed to investigate the differences in CKD staging with the most commonly used equations and to analyze sources of discrepancy. Methods: A total of 966 centenarians were enrolled in this study from June 2014 to December 2016 in Hainan province, China. The GFR with the Modification of Diet in Renal Disease (MDRD), Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) and Berlin Initiative Study 1 (BIS1) equations were estimated. Agreement between these equations was investigated with the k statistic and Bland-Altman plots. Sources of discrepancy were investigated by partial correlation analysis. Results: The k values of the MDRD and CKD-EPI equations, MDRD and BIS1 equations, and CKD-EPI and BIS1 equations were 0.610, 0.253, and 0.381, respectively. Serum creatinine (Scr) explained 10.96%, 41.60% and 17.06% of the variability in these three comparisons, respectively. Serum uric acid (SUA) explained 3.65% and 5.43% of the variability in the first 2 comparisons, respectively. Gender was associated with significant differences in these 3 comparisons (P<0.001). Conclusions: The strengths of agreement between the MDRD and CKD-EPI equations were substantial, but those between the MDRD and BIS 1 equations and the CKD-EPI and BIS 1 equations were fair. The difference in CKD staging of the first 2 comparisons strongly depended on Scr, SUA and gender, and that of CKD-EPI and BIS1 equations strongly depended on Scr and gender. The incidence at various stages of CKD staging was quite different. Thus, a new equation that is more suitable for the elderly needs to be built in the future.
