We present measurements of the 2p-3d transition opacity of a hot molybdenum-scandium sample with nearly half-vacant molybdenum M-shell configurations.A plastic-tamped molybdenum-scandium foil sample is radiatively hea...We present measurements of the 2p-3d transition opacity of a hot molybdenum-scandium sample with nearly half-vacant molybdenum M-shell configurations.A plastic-tamped molybdenum-scandium foil sample is radiatively heated to high temperature in a compact D-shaped gold Hohlraum driven by∼30 kJ laser energy at the SG-100 kJ laser facility.X rays transmitted through the molybdenum and scandium plasmas are diffracted by crystals and finally recorded by image plates.The electron temperatures in the sample in particular spatial and temporal zones are determined by the K-shell absorption of the scandium plasma.A combination of the IRAD3D view factor code and the MULTI hydrodynamic code is used to simulate the spatial distribution and temporal behavior of the sample temperature and density.The inferred temperature in the molybdenum plasma reaches a average of 138±11 eV.A detailed configuration-accounting calculation of the n=2–3 transition absorption of the molybdenum plasma is compared with experimental measurements and quite good agreement is found.The present measurements provide an opportunity to test opacity models for complicated M-shell configurations.展开更多
A self-consistent and precise method to determine the time-dependent radiative albedo,i.e.,the ratio of the reemission flux to the incident flux,for an indirect-drive inertial confinement fusion Hohlraum wall material...A self-consistent and precise method to determine the time-dependent radiative albedo,i.e.,the ratio of the reemission flux to the incident flux,for an indirect-drive inertial confinement fusion Hohlraum wall material is proposed.A specially designed symmetrical triple-cavity gold Hohlraum is used to create approximately constant and near-equilibrium uniform radiation with a peak temperature of 160 eV.The incident flux at the secondary cavity waist is obtained from flux balance analysis and from the shock velocity of a standard sample.The results agree well owing to the symmetrical radiation in the secondary cavity.A self-consistent and precise time-dependent radiative albedo is deduced from the reliable reemission flux and the incident flux,and the result from the shock velocity is found to have a smaller uncertainty than that from the multi-angle flux balance analysis,and also to agree well with the result of a simulation using the HYADES opacity.展开更多
After reviewing the development of industrial manufacturing, a novel concept called social manufacturing(SM) and service are proposed as an innovative manufacturing solution for the coming personalized customization e...After reviewing the development of industrial manufacturing, a novel concept called social manufacturing(SM) and service are proposed as an innovative manufacturing solution for the coming personalized customization era. SM can realize a customer's requirements of "from mind to products", and fulfill tangible and intangible needs of a prosumer, i.e., producer and consumer at the same time. It represents a manufacturing trend,and is expected to become popular in more and more industries.First, a comparison between mass customization and SM is given out, and the basis and motivation from social network to SM is analyzed. Then, its basic theories and supporting technologies,like Internet of Things(Io T), social networks, cloud computing,3 D printing, and intelligent systems, are introduced and analyzed,and an SM platform prototype is developed. Finally, three transformation modes towards SM and 3 D printing are suggested for different user cases.展开更多
Digital rock physics(DRP)is a paramount technology to improve the economic benefits of oil and gas fields,devise more scientific oil and gas field development plans,and create digital oil and gas fields.Currently,a si...Digital rock physics(DRP)is a paramount technology to improve the economic benefits of oil and gas fields,devise more scientific oil and gas field development plans,and create digital oil and gas fields.Currently,a significant gap is present between DRP theory and practical applications.Conventional digital-core construction focuses only on simple cores,and the recognition and segmentation effect of fractures and pores of complex cores is poor.The identification of rock minerals is inaccurate,which leads to the difference between the digital and actual cores.To promote the application of DRP in developing oil and gas fields,based on the high-precision X-ray computed tomography scanning technology,the U-Net deep learning model of the full convolution neural network is used to segment the pores,fractures,and matrix from the complex rock core with natural fractures innovatively.Simultaneously,the distribution of rock minerals is divided,and the distribution of rock conditions is corrected by X-ray diffraction.A pore—fracture network model is established based on the equivalent radius,which lays the foundation for fluid seepage simulation.Finally,the accuracy of the established a digital core is verified by the porosity measured via nuclear magnetic resonance technology,which is of great significance to the development and application of DRP in oil and gas fields.展开更多
Social manufacturing(SM), a novel distributed,collaborative and intelligent manufacturing mode, is proposed and developed for high-end apparel customization. The main components of SM cloud are designed, and its resea...Social manufacturing(SM), a novel distributed,collaborative and intelligent manufacturing mode, is proposed and developed for high-end apparel customization. The main components of SM cloud are designed, and its research topics are summarized. Then, SM's key technologies are studied. 3D technologies for apparel customization, like 3D modeling, 3D fitting mirror and 3D customization, are developed to improve the customization precision and user experience. Information based collaborative management is realized to share, communicate,and handle the information efficiently among all groups and individuals of SM cloud. Suppliers' evaluation mechanism is designed to support the optimal decisions making. Next, SM cloud is constructed in five layers for high-end apparel customization.By using SM cloud based crowd-sourcing, social resources can be allocated rationally and utilized efficiently, consumer can customize the product in any processes like innovation, design,making, marketing and service, and traditional apparel enterprise can be upgraded into SM mode for keeping it competitive in the future customization markets.展开更多
Based on ACP(artificial systems,computational experiments,and parallel execution)methodology,parallel control and management has become a popularly systematic and complete solution for the control and management of co...Based on ACP(artificial systems,computational experiments,and parallel execution)methodology,parallel control and management has become a popularly systematic and complete solution for the control and management of complex systems.This paper focuses on summarizing comprehensive review of the research literature of parallel control and management achieved in the recent years including the theoretical framework,core technologies,and the application demonstration.The future research,application directions,and suggestions are also discussed.展开更多
With most countries paying attention to the environment protection, hybrid electric vehicles have become a focus of automobile research and development due to the characteristics of energy saving and low emission. Pow...With most countries paying attention to the environment protection, hybrid electric vehicles have become a focus of automobile research and development due to the characteristics of energy saving and low emission. Power follower control strategy(PFCS) and DC-link voltage control strategy are two sorts of control strategies for series hybrid electric vehicles(HEVs). Combining those two control strategies is a new idea for control strategy of series hybrid electric vehicles. By tuning essential parameters which are the defined constants under DClink voltage control and under PFCS, the points of minimum mass of equivalent fuel consumption(EFC) corresponding to a series of variables are marked for worldwide harmonized light vehicles test procedure(WLTP). The fuel economy of series HEVs with the combination control schemes performs better compared with individual control scheme. The results show the effects of the combination control schemes for series HEVs driving in an urban environment.展开更多
It is important to identify and remove the wastes not only from manufacturing process, but also from nonmanufacturing process. In the last several decades, significant research achievements and practice benefits have ...It is important to identify and remove the wastes not only from manufacturing process, but also from nonmanufacturing process. In the last several decades, significant research achievements and practice benefits have been achieved about removing wastes from manufacturing process. Since the1990 s, some researchers and lean practitioners have paid more attention to removing waste from non-manufacturing process.Based on the authors' research work and industrial practice, the paper introduces a kind of lean approach for removing waste from non-manufacturing process. In its case study, the order handling process in a value chain is described with respect to a factory and its downstream distribution centers(DCs). The paper proposes a lean approach solution for creating the improved order handling process, and analyze how great improvements in performance can be achieved. As a result, the significant achievement has created a win-win scenario for both the nonmanufacturing process in a factory and non-manufacturing facilities(like DCs) across the value chain. It demonstrates that improvements have been made by removing waste from the non-manufacturing process that takes place within a factory as well as with external participants through the whole value chain. Likewise, the proposed lean approach has helped the case companies to achieve greater levels of efficiency and more benefits. Finally, some conclusions are drawn.展开更多
A practical experimental method is proposed to investigate thermal transport by characterizing the motion of plasma flows through a x-ray spectroscopic technique using tracers.By simultaneously measuring multiple para...A practical experimental method is proposed to investigate thermal transport by characterizing the motion of plasma flows through a x-ray spectroscopic technique using tracers.By simultaneously measuring multiple parameters,namely,the mass-ablation rate,the temporal evolution of plasma flow velocities and trajectories and the temperature,it is possible to observe a variety of physical processes,such as shock wave compression,heating by thermal waves,and plasma thermal expansion,and to determine their relative importance in different phases during the irradiation of CH and Au targets.From a comparison with hydrodynamic simulations,we find significant differences in the motion of the plasma flows between CH and Au,which can be attributed to different sensitivities to the thermal transport process.There are also differences in the ablation and electron temperature histories of the two materials.These results confirm that velocities and trajectories of plasma motion can provide useful evidence in the investigation of thermal conduction,and the approach presented here deserves more attention in the context of inertial confinement fusion and high-energy-density physics.展开更多
Dielectronic recombination is an important process in high temperature plasmas. In the present work, the KLn （n=L, M, N and O） DR resonance strengths of He-like to O-like xenon ions are measured at the Shanghai elec...Dielectronic recombination is an important process in high temperature plasmas. In the present work, the KLn （n=L, M, N and O） DR resonance strengths of He-like to O-like xenon ions are measured at the Shanghai electron beam ion trap using a fast electron beam energy scanning method. The experiment uncertainty reaches about 6% with significant improvement of statistics. A relativistic configuration interaction calculation is also made. Theoretical results agree with the experiment results within 15% in most cases.展开更多
Objective To investigate the prognostic value of serum carcinoembryonic antigen(CEA)and controlling nutritional status(CONUT)score in patients with colorectal cancer.Methods We retrospectively studied 261 patients wit...Objective To investigate the prognostic value of serum carcinoembryonic antigen(CEA)and controlling nutritional status(CONUT)score in patients with colorectal cancer.Methods We retrospectively studied 261 patients with colorectal cancer in our hospital.The patients were divided into two groups by CONUT=3 and CEA=5 ng/mL,and the effects of CONUT score and CEA level on the prognosis and clinicopathological parameters were statistically analyzed.Results(1)Different CONUT scores were significantly correlated with age,tumor diameter,differentiation type,and T stage(P<0.05).The older the patient was,the larger the tumor diameter,undifferentiated tumor,and T stage were,the higher the CONUT score was.(2)Seventy-five patients died during the follow-up period,and 45 patients died of progression or recurrence of colorectal cancer.The 5-year overall survival(OS)rate of the low CONUT score group was significantly higher than that of the high CONUT score group,and the 5-year OS rate of the low CEA group was significantly higher than that of the high CEA group;the difference was statistically significant(P<0.01).(3)According to the serum CEA level and CONUT score,the 5-year survival rates of CEAlow/CONUTlow,CEAlow/CONUThigh,CEAhigh/CONUTlow,and CEAhigh/CONUThigh were 84.7%,69%,55.3%,and 36.1%respectively,with statistical significance(P<0.01).(4)The Cox multivariate analysis showed that age,CONUT score,CEA combined with CONUT score,lymph node metastasis,and distant metastasis were independent risk factors for the prognosis of colorectal cancer patients.Conclusion:The combination of CEA detection and CONUT score can more accurately judge the prognosis of colorectal cancer patients.展开更多
Most recent progress on the Suzuki-Miyaura, Heck and Sonogashira cross-coupling reactions, induced by heterobimetallic Pd-Ln coordination polymers as heterogeneous catalysts has been accurately reviewed. Physical-chem...Most recent progress on the Suzuki-Miyaura, Heck and Sonogashira cross-coupling reactions, induced by heterobimetallic Pd-Ln coordination polymers as heterogeneous catalysts has been accurately reviewed. Physical-chemical characterization of the Pd-Ln composite materials by adequate physical methods revealed the distinct structure and configuration of the two- and three-dimensional frameworks. The important contribution of the coordination polymers as catalyst supports to finely modulating the catalytic activity and chemoselectivity has been considered. Published results illustrate the high activity and chemoselectivity of Pd-Ln coordination polymers in cross-coupling reactions, excellent catalyst recoverability and recyclability as well as low catalyst loading or metal leaching, under optimized reaction conditions. The particular effect of the solvent, base, aryl halide or related reagents in governing the main steps of the Pd catalytic cycle has been particularly outlined. In addition, the well-established cooperative effect of the lanthanides with palladium, with emphasis on the synergism between different metals in heterobimetallic catalytic systems, has been highlighted.展开更多
Despite the critical role that middleboxes play in introducing new network functionality,management and innovation of them are still severe challenges for network operators,since traditional middleboxes based on hardw...Despite the critical role that middleboxes play in introducing new network functionality,management and innovation of them are still severe challenges for network operators,since traditional middleboxes based on hardware lack service flexibility and scalability.Recently,though new networking technologies,such as network function virtualization(NFV) and softwaredefined networking(SDN),are considered as very promising drivers to design cost-efficient middlebox service architectures,how to guarantee transmission efficiency has drawn little attention under the condition of adding virtual service process for traffic.Therefore,we focus on the service deployment problem to reduce the transport delay in the network with a combination of NFV and SDN.First,a framework is designed for service placement decision,and an integer linear programming model is proposed to resolve the service placement and minimize the network transport delay.Then a heuristic solution is designed based on the improved quantum genetic algorithm.Experimental results show that our proposed method can calculate automatically the optimal placement schemes.Our scheme can achieve lower overall transport delay for a network compared with other schemes and reduce 30% of the average traffic transport delay compared with the random placement scheme.展开更多
基金supported by the National Nature Science Foundation of China(Grant Nos.12335015,12375238,12374261,11734013,and 11704350)the Presidential Foundation of the China Academy of Engineering Physics(Grant No.YZJJLX2017010)+2 种基金the CAEP Foundation(Grant No.CX2019023)the Science Challenge Project(Grant Nos.TZ2018001 and TZ2018005)the National Key R&D Program of China(Grant No.2017YFA0403200).
文摘We present measurements of the 2p-3d transition opacity of a hot molybdenum-scandium sample with nearly half-vacant molybdenum M-shell configurations.A plastic-tamped molybdenum-scandium foil sample is radiatively heated to high temperature in a compact D-shaped gold Hohlraum driven by∼30 kJ laser energy at the SG-100 kJ laser facility.X rays transmitted through the molybdenum and scandium plasmas are diffracted by crystals and finally recorded by image plates.The electron temperatures in the sample in particular spatial and temporal zones are determined by the K-shell absorption of the scandium plasma.A combination of the IRAD3D view factor code and the MULTI hydrodynamic code is used to simulate the spatial distribution and temporal behavior of the sample temperature and density.The inferred temperature in the molybdenum plasma reaches a average of 138±11 eV.A detailed configuration-accounting calculation of the n=2–3 transition absorption of the molybdenum plasma is compared with experimental measurements and quite good agreement is found.The present measurements provide an opportunity to test opacity models for complicated M-shell configurations.
基金This work was supported by the National Natural Science Foundation of China(Grant No.12004351).
文摘A self-consistent and precise method to determine the time-dependent radiative albedo,i.e.,the ratio of the reemission flux to the incident flux,for an indirect-drive inertial confinement fusion Hohlraum wall material is proposed.A specially designed symmetrical triple-cavity gold Hohlraum is used to create approximately constant and near-equilibrium uniform radiation with a peak temperature of 160 eV.The incident flux at the secondary cavity waist is obtained from flux balance analysis and from the shock velocity of a standard sample.The results agree well owing to the symmetrical radiation in the secondary cavity.A self-consistent and precise time-dependent radiative albedo is deduced from the reliable reemission flux and the incident flux,and the result from the shock velocity is found to have a smaller uncertainty than that from the multi-angle flux balance analysis,and also to agree well with the result of a simulation using the HYADES opacity.
基金supported in part by the National Natural Science Foundation of China(61233001,61773381,71232006,61304201,61533019,61773382)Finnish TEKES’s project“So Ma2020:Social Manufacturing”(2015-2017,211560)Chinese Guangdong’s S&T project(2015B010103001,2016B090910001)
文摘After reviewing the development of industrial manufacturing, a novel concept called social manufacturing(SM) and service are proposed as an innovative manufacturing solution for the coming personalized customization era. SM can realize a customer's requirements of "from mind to products", and fulfill tangible and intangible needs of a prosumer, i.e., producer and consumer at the same time. It represents a manufacturing trend,and is expected to become popular in more and more industries.First, a comparison between mass customization and SM is given out, and the basis and motivation from social network to SM is analyzed. Then, its basic theories and supporting technologies,like Internet of Things(Io T), social networks, cloud computing,3 D printing, and intelligent systems, are introduced and analyzed,and an SM platform prototype is developed. Finally, three transformation modes towards SM and 3 D printing are suggested for different user cases.
基金Science and Technology Cooperation Project of the CNPC-SWPU Innovation Alliance(No.2020CX010501)National Science and Technology Major ProjectNational Natural Science Foundation of China Petrochemical Joint Fund Project(U1762107)
文摘Digital rock physics(DRP)is a paramount technology to improve the economic benefits of oil and gas fields,devise more scientific oil and gas field development plans,and create digital oil and gas fields.Currently,a significant gap is present between DRP theory and practical applications.Conventional digital-core construction focuses only on simple cores,and the recognition and segmentation effect of fractures and pores of complex cores is poor.The identification of rock minerals is inaccurate,which leads to the difference between the digital and actual cores.To promote the application of DRP in developing oil and gas fields,based on the high-precision X-ray computed tomography scanning technology,the U-Net deep learning model of the full convolution neural network is used to segment the pores,fractures,and matrix from the complex rock core with natural fractures innovatively.Simultaneously,the distribution of rock minerals is divided,and the distribution of rock conditions is corrected by X-ray diffraction.A pore—fracture network model is established based on the equivalent radius,which lays the foundation for fluid seepage simulation.Finally,the accuracy of the established a digital core is verified by the porosity measured via nuclear magnetic resonance technology,which is of great significance to the development and application of DRP in oil and gas fields.
基金supported in part by the National Natural Science Foundation of China(71232006,61533019,61233001,61304201,61773381,61773382,71472174,71702182)Finnish TEKESs project“SoMa 2020:Social Manufacturing”(2015-2017,211560)+1 种基金Chinese Guangdong’s S&T Project(2015B010103001,2016B090910001,2017B090912001)Dongguan’s Innovation Talents Project(Gang Xiong)
文摘Social manufacturing(SM), a novel distributed,collaborative and intelligent manufacturing mode, is proposed and developed for high-end apparel customization. The main components of SM cloud are designed, and its research topics are summarized. Then, SM's key technologies are studied. 3D technologies for apparel customization, like 3D modeling, 3D fitting mirror and 3D customization, are developed to improve the customization precision and user experience. Information based collaborative management is realized to share, communicate,and handle the information efficiently among all groups and individuals of SM cloud. Suppliers' evaluation mechanism is designed to support the optimal decisions making. Next, SM cloud is constructed in five layers for high-end apparel customization.By using SM cloud based crowd-sourcing, social resources can be allocated rationally and utilized efficiently, consumer can customize the product in any processes like innovation, design,making, marketing and service, and traditional apparel enterprise can be upgraded into SM mode for keeping it competitive in the future customization markets.
基金supported in part by the National Key Research and Development Program of China(2018YFB1702701)the National Natural Science Foundation of China(61773381,61773382)+1 种基金Dongguan’s Innovation Talents Project(Gang Xiong)Chinese Guangdong’s Science and Technology Project(2017B090912001)
文摘Based on ACP(artificial systems,computational experiments,and parallel execution)methodology,parallel control and management has become a popularly systematic and complete solution for the control and management of complex systems.This paper focuses on summarizing comprehensive review of the research literature of parallel control and management achieved in the recent years including the theoretical framework,core technologies,and the application demonstration.The future research,application directions,and suggestions are also discussed.
基金supported in part by the National Natural Science Foundation of China(61773382,61773381,61533019)Chinese Guangdongs S&T projects(2016B090910001,2017B090912001)+1 种基金2016 S&T Benefiting Special Project(16-6-2-62-nsh)of Qingdao Achievements Transformation ProgramDongguan Innovation Talents Project(Gang Xiong)
文摘With most countries paying attention to the environment protection, hybrid electric vehicles have become a focus of automobile research and development due to the characteristics of energy saving and low emission. Power follower control strategy(PFCS) and DC-link voltage control strategy are two sorts of control strategies for series hybrid electric vehicles(HEVs). Combining those two control strategies is a new idea for control strategy of series hybrid electric vehicles. By tuning essential parameters which are the defined constants under DClink voltage control and under PFCS, the points of minimum mass of equivalent fuel consumption(EFC) corresponding to a series of variables are marked for worldwide harmonized light vehicles test procedure(WLTP). The fuel economy of series HEVs with the combination control schemes performs better compared with individual control scheme. The results show the effects of the combination control schemes for series HEVs driving in an urban environment.
基金supported in part by the National Natural Science Foundation of China (61773381,61773382,61533019,91520301)Finnish TEKES’s Project "SoMa2020:Social Manufacturing" (211560)+1 种基金Chinese Guangdong’s S&T Project (2015B010103001,2016B090910001,2017B090912001)Dongguan’s Innovation Talents Project (Gang Xiong)
文摘It is important to identify and remove the wastes not only from manufacturing process, but also from nonmanufacturing process. In the last several decades, significant research achievements and practice benefits have been achieved about removing wastes from manufacturing process. Since the1990 s, some researchers and lean practitioners have paid more attention to removing waste from non-manufacturing process.Based on the authors' research work and industrial practice, the paper introduces a kind of lean approach for removing waste from non-manufacturing process. In its case study, the order handling process in a value chain is described with respect to a factory and its downstream distribution centers(DCs). The paper proposes a lean approach solution for creating the improved order handling process, and analyze how great improvements in performance can be achieved. As a result, the significant achievement has created a win-win scenario for both the nonmanufacturing process in a factory and non-manufacturing facilities(like DCs) across the value chain. It demonstrates that improvements have been made by removing waste from the non-manufacturing process that takes place within a factory as well as with external participants through the whole value chain. Likewise, the proposed lean approach has helped the case companies to achieve greater levels of efficiency and more benefits. Finally, some conclusions are drawn.
基金the National Key R&D Program of China under Grant No.2017YFA0403200the National Nature Science Foundation(NSFC)of China under Grant Nos.12005206,11734013,11774321,and 12004351+2 种基金the Science Challenge Project under Grant Nos.TZ2018001 and TZ2018005the CAEP foundation under Grant Nos.YZJLX2017010 and 2018011the foundation for Development of Science and Technology of the China Academy of Engineering Physics under Grant No.CX2019023.
文摘A practical experimental method is proposed to investigate thermal transport by characterizing the motion of plasma flows through a x-ray spectroscopic technique using tracers.By simultaneously measuring multiple parameters,namely,the mass-ablation rate,the temporal evolution of plasma flow velocities and trajectories and the temperature,it is possible to observe a variety of physical processes,such as shock wave compression,heating by thermal waves,and plasma thermal expansion,and to determine their relative importance in different phases during the irradiation of CH and Au targets.From a comparison with hydrodynamic simulations,we find significant differences in the motion of the plasma flows between CH and Au,which can be attributed to different sensitivities to the thermal transport process.There are also differences in the ablation and electron temperature histories of the two materials.These results confirm that velocities and trajectories of plasma motion can provide useful evidence in the investigation of thermal conduction,and the approach presented here deserves more attention in the context of inertial confinement fusion and high-energy-density physics.
基金supported by the National Key Research and Development Program of China under Grant No.2017YFA0402300
文摘Dielectronic recombination is an important process in high temperature plasmas. In the present work, the KLn （n=L, M, N and O） DR resonance strengths of He-like to O-like xenon ions are measured at the Shanghai electron beam ion trap using a fast electron beam energy scanning method. The experiment uncertainty reaches about 6% with significant improvement of statistics. A relativistic configuration interaction calculation is also made. Theoretical results agree with the experiment results within 15% in most cases.
基金Supported by a grant from the Support Program of Sichuan Science and Technology Department(No.2018sz2311).
文摘Objective To investigate the prognostic value of serum carcinoembryonic antigen(CEA)and controlling nutritional status(CONUT)score in patients with colorectal cancer.Methods We retrospectively studied 261 patients with colorectal cancer in our hospital.The patients were divided into two groups by CONUT=3 and CEA=5 ng/mL,and the effects of CONUT score and CEA level on the prognosis and clinicopathological parameters were statistically analyzed.Results(1)Different CONUT scores were significantly correlated with age,tumor diameter,differentiation type,and T stage(P<0.05).The older the patient was,the larger the tumor diameter,undifferentiated tumor,and T stage were,the higher the CONUT score was.(2)Seventy-five patients died during the follow-up period,and 45 patients died of progression or recurrence of colorectal cancer.The 5-year overall survival(OS)rate of the low CONUT score group was significantly higher than that of the high CONUT score group,and the 5-year OS rate of the low CEA group was significantly higher than that of the high CEA group;the difference was statistically significant(P<0.01).(3)According to the serum CEA level and CONUT score,the 5-year survival rates of CEAlow/CONUTlow,CEAlow/CONUThigh,CEAhigh/CONUTlow,and CEAhigh/CONUThigh were 84.7%,69%,55.3%,and 36.1%respectively,with statistical significance(P<0.01).(4)The Cox multivariate analysis showed that age,CONUT score,CEA combined with CONUT score,lymph node metastasis,and distant metastasis were independent risk factors for the prognosis of colorectal cancer patients.Conclusion:The combination of CEA detection and CONUT score can more accurately judge the prognosis of colorectal cancer patients.
基金supported by National Key Research and Development Program of China(Grant No.2020YFC1909300).
文摘Most recent progress on the Suzuki-Miyaura, Heck and Sonogashira cross-coupling reactions, induced by heterobimetallic Pd-Ln coordination polymers as heterogeneous catalysts has been accurately reviewed. Physical-chemical characterization of the Pd-Ln composite materials by adequate physical methods revealed the distinct structure and configuration of the two- and three-dimensional frameworks. The important contribution of the coordination polymers as catalyst supports to finely modulating the catalytic activity and chemoselectivity has been considered. Published results illustrate the high activity and chemoselectivity of Pd-Ln coordination polymers in cross-coupling reactions, excellent catalyst recoverability and recyclability as well as low catalyst loading or metal leaching, under optimized reaction conditions. The particular effect of the solvent, base, aryl halide or related reagents in governing the main steps of the Pd catalytic cycle has been particularly outlined. In addition, the well-established cooperative effect of the lanthanides with palladium, with emphasis on the synergism between different metals in heterobimetallic catalytic systems, has been highlighted.
基金supported by the National Basic Research Program(973)of China(Nos.2012CB315901 and 2013CB329104)the National Natural Science Foundation of China(Nos.61309019,61372121,61572519,and 61502530)the National High-Tech R&D Program(863)of China(Nos.2015AA016102 and 2013AA013505)
文摘Despite the critical role that middleboxes play in introducing new network functionality,management and innovation of them are still severe challenges for network operators,since traditional middleboxes based on hardware lack service flexibility and scalability.Recently,though new networking technologies,such as network function virtualization(NFV) and softwaredefined networking(SDN),are considered as very promising drivers to design cost-efficient middlebox service architectures,how to guarantee transmission efficiency has drawn little attention under the condition of adding virtual service process for traffic.Therefore,we focus on the service deployment problem to reduce the transport delay in the network with a combination of NFV and SDN.First,a framework is designed for service placement decision,and an integer linear programming model is proposed to resolve the service placement and minimize the network transport delay.Then a heuristic solution is designed based on the improved quantum genetic algorithm.Experimental results show that our proposed method can calculate automatically the optimal placement schemes.Our scheme can achieve lower overall transport delay for a network compared with other schemes and reduce 30% of the average traffic transport delay compared with the random placement scheme.
