AIM: To describe the incidence of esophageal cancer (EC)in Cixian, a county of Hebei province during 1974-1996. Weanalyzed the sex and age characteristics as well as thegeographic distribution of EC, in order to deter...AIM: To describe the incidence of esophageal cancer (EC)in Cixian, a county of Hebei province during 1974-1996. Weanalyzed the sex and age characteristics as well as thegeographic distribution of EC, in order to determine theimpact so that methods of preventing and controlling EC inCixian can be put in place.METHODS: Since the early 1970s, the cancer registrysystem has been established, which collects the cancerincidence in Cixian county. The malignant tumors were codedaccording to International Classification of Disease IX (ICD-9). All the data were checked and analyzed using EPIINFO.RESULTS: The trend of the incidence rate of EC from 1974to 1996 had declined, (229.9/100 000 vs 178.5/100 000, Oddsratio= 1.47, 95 % CI: 1.32～1.63, X2=52.89. trend X2=26.54,P＜0.001). The incidence rate of males declined significantly(281.81/100 000 vs 157.96/100 000, Odds ratio=1.61, 95 %CI: 1.41～1.84, X2=47.85. Trend X2=44.86, P＜0.001),whereas, the females remained steady (157.96/100 000 vs133.41/100 000, odds ratio=1.28, 95 % CI:1.17～1.49,X2=9.26. trend X2=2.69, P＞0.05). Male average annualincidence rate was 142.80/100 000 and the female's was95.18/100 000. The sex ratio (males to females) was 1.50:1.The incidence rate was increasing along with the age. As tothe geographic distribution, the incidence rate in mountainousareas and hilly areas showed a significantly declining trend(mountainous areas, trend X2=149.93, P＜0.001; hilly areas,trend X2=42.70, P＜0.001). The incidence rate of EC in plainareas had increased (trend X2=22.39, P＜0.001).CONCLUSION: The incidence rate of EC in Cixian countyshows a trend and has declined after two decades, especiallyin mountainous area. But compared to other regions in theworld, Cixian county still had a high incidence rate of EC.展开更多
AIM: To define the age scope of high-risk population for esophageal cancer (EC) in Ci county. METHODS: The results of endoscopic examination of 2 013 subjects, cytological screening of 16 763 persons and records of 9 ...AIM: To define the age scope of high-risk population for esophageal cancer (EC) in Ci county. METHODS: The results of endoscopic examination of 2 013 subjects, cytological screening of 16 763 persons and records of 9 265 patients with EC were analyzed by Ridit methods, the standard age group was 45-49 year group. RESULTS: The average age of patients with moderate esophageal epithelium dysplasia by endoscopic examination was 53.5 years, of severe esophageal epithelium dysplasia, 51.4 years, early EC, 55.6 years. The average age of stage one severe epithelium dysplasia (SEEDⅠ) by cytological screening was 51.2 years, of stage two severe epithelium esophageal dysplasia (SEED Ⅱ) 51.6 years, of advanced EC 61.7 years. In the group of 40-year olds, the value of Ridit by pathological diagnosis was 0.46, 95% CI, 0.45-0.47, that by cytological diagnosis was 0.45, 95% CI, 0.43-0.47. As the age increased at five-year intervals, the value of Ridit increased significantly. CONCLUSION: In Ci county of a high incidence area of EC, the age definition of high-risk population should be above 45 years.展开更多
基金The National Ninth-Five-Year Scientific Championship Project No.96-906-01-01
文摘AIM: To describe the incidence of esophageal cancer (EC)in Cixian, a county of Hebei province during 1974-1996. Weanalyzed the sex and age characteristics as well as thegeographic distribution of EC, in order to determine theimpact so that methods of preventing and controlling EC inCixian can be put in place.METHODS: Since the early 1970s, the cancer registrysystem has been established, which collects the cancerincidence in Cixian county. The malignant tumors were codedaccording to International Classification of Disease IX (ICD-9). All the data were checked and analyzed using EPIINFO.RESULTS: The trend of the incidence rate of EC from 1974to 1996 had declined, (229.9/100 000 vs 178.5/100 000, Oddsratio= 1.47, 95 % CI: 1.32～1.63, X2=52.89. trend X2=26.54,P＜0.001). The incidence rate of males declined significantly(281.81/100 000 vs 157.96/100 000, Odds ratio=1.61, 95 %CI: 1.41～1.84, X2=47.85. Trend X2=44.86, P＜0.001),whereas, the females remained steady (157.96/100 000 vs133.41/100 000, odds ratio=1.28, 95 % CI:1.17～1.49,X2=9.26. trend X2=2.69, P＞0.05). Male average annualincidence rate was 142.80/100 000 and the female's was95.18/100 000. The sex ratio (males to females) was 1.50:1.The incidence rate was increasing along with the age. As tothe geographic distribution, the incidence rate in mountainousareas and hilly areas showed a significantly declining trend(mountainous areas, trend X2=149.93, P＜0.001; hilly areas,trend X2=42.70, P＜0.001). The incidence rate of EC in plainareas had increased (trend X2=22.39, P＜0.001).CONCLUSION: The incidence rate of EC in Cixian countyshows a trend and has declined after two decades, especiallyin mountainous area. But compared to other regions in theworld, Cixian county still had a high incidence rate of EC.
基金Supported by the National Eighth five-year and tenth five year key Scientific Project, No. 85-914-01-02, 2001BA703B10
文摘AIM: To define the age scope of high-risk population for esophageal cancer (EC) in Ci county. METHODS: The results of endoscopic examination of 2 013 subjects, cytological screening of 16 763 persons and records of 9 265 patients with EC were analyzed by Ridit methods, the standard age group was 45-49 year group. RESULTS: The average age of patients with moderate esophageal epithelium dysplasia by endoscopic examination was 53.5 years, of severe esophageal epithelium dysplasia, 51.4 years, early EC, 55.6 years. The average age of stage one severe epithelium dysplasia (SEEDⅠ) by cytological screening was 51.2 years, of stage two severe epithelium esophageal dysplasia (SEED Ⅱ) 51.6 years, of advanced EC 61.7 years. In the group of 40-year olds, the value of Ridit by pathological diagnosis was 0.46, 95% CI, 0.45-0.47, that by cytological diagnosis was 0.45, 95% CI, 0.43-0.47. As the age increased at five-year intervals, the value of Ridit increased significantly. CONCLUSION: In Ci county of a high incidence area of EC, the age definition of high-risk population should be above 45 years.
