To explore the relationship between the heat-clearing and detoxicating functions and the bacteriostatic actions of berberine hydrochloride (Ber. H), chlorogenic acid (Chlo. A), and baicalin (Bai), their concentrations...To explore the relationship between the heat-clearing and detoxicating functions and the bacteriostatic actions of berberine hydrochloride (Ber. H), chlorogenic acid (Chlo. A), and baicalin (Bai), their concentrations in rabbit body fluid were compared with their minimal inhibitory concentrations (MICs). Their concentrations in rabbit blood and tissue fluid were determined by reversed-phase high performance liquid chromatography, and their MICs to Escherichia coli were determined by tube dilution method. The results showed that the peak concentrations of Ber. H, Chlo. A, and Bai in rabbit blood were 3.2, 5.03, and 7.63 μg mL-1, and in rabbit tissue fluid were 0.12, 0.11, and 0.12 μg mL-1, respectively. Their MICs to E. coli were, respectively, 1.0 × 103, 3.75 × 103, and 6.75 × 103 μg mL-1, which were far higher than the concentrations in rabbit body fluids. This study indicates that Ber. H, Chlo. A, and Bai have weak bacteriostatic actions and do not reach their effective inhibitory concentrations in rabbit body fluids, and their heat-clearing and detoxicating functions are independent on the bacteriostatic actions.展开更多
介绍了废硫酸热分解的过程和热量计算,详细介绍了在硫铁矿沸腾焙烧炉中掺烧烷基化废酸制取硫酸的方法。利用硫铁矿沸腾焙烧释放的反应热使烷基化废酸裂解为SO_2。裂解气汇入硫铁矿沸腾焙烧炉气,进入制酸系统。掺烧1 t w(H_2SO_4)90.5%...介绍了废硫酸热分解的过程和热量计算,详细介绍了在硫铁矿沸腾焙烧炉中掺烧烷基化废酸制取硫酸的方法。利用硫铁矿沸腾焙烧释放的反应热使烷基化废酸裂解为SO_2。裂解气汇入硫铁矿沸腾焙烧炉气,进入制酸系统。掺烧1 t w(H_2SO_4)90.5%烷基化废酸费用为463.5元。当烷基化废酸处理费为250元/t时,硫铁矿制酸装置可考虑掺烧烷基化废酸。展开更多
基金supported by a grant from Beijing Natural Science Foundation, China (6021001)agrant from Learning Innovative Group Programs of Beijing Education Committee, China (5090245)
文摘To explore the relationship between the heat-clearing and detoxicating functions and the bacteriostatic actions of berberine hydrochloride (Ber. H), chlorogenic acid (Chlo. A), and baicalin (Bai), their concentrations in rabbit body fluid were compared with their minimal inhibitory concentrations (MICs). Their concentrations in rabbit blood and tissue fluid were determined by reversed-phase high performance liquid chromatography, and their MICs to Escherichia coli were determined by tube dilution method. The results showed that the peak concentrations of Ber. H, Chlo. A, and Bai in rabbit blood were 3.2, 5.03, and 7.63 μg mL-1, and in rabbit tissue fluid were 0.12, 0.11, and 0.12 μg mL-1, respectively. Their MICs to E. coli were, respectively, 1.0 × 103, 3.75 × 103, and 6.75 × 103 μg mL-1, which were far higher than the concentrations in rabbit body fluids. This study indicates that Ber. H, Chlo. A, and Bai have weak bacteriostatic actions and do not reach their effective inhibitory concentrations in rabbit body fluids, and their heat-clearing and detoxicating functions are independent on the bacteriostatic actions.
文摘介绍了废硫酸热分解的过程和热量计算,详细介绍了在硫铁矿沸腾焙烧炉中掺烧烷基化废酸制取硫酸的方法。利用硫铁矿沸腾焙烧释放的反应热使烷基化废酸裂解为SO_2。裂解气汇入硫铁矿沸腾焙烧炉气,进入制酸系统。掺烧1 t w(H_2SO_4)90.5%烷基化废酸费用为463.5元。当烷基化废酸处理费为250元/t时,硫铁矿制酸装置可考虑掺烧烷基化废酸。
