We reported a nano-Ag/liquid crystalline elastomer（LCE） nanocomposite by incorporating silver nanopar- ticles into a monodomain polysiloxane-based LCE matrix via a novel experimental protocol. The photo-thermo- mech...We reported a nano-Ag/liquid crystalline elastomer（LCE） nanocomposite by incorporating silver nanopar- ticles into a monodomain polysiloxane-based LCE matrix via a novel experimental protocol. The photo-thermo- mechanical actuation of the LCE matrix was realized via the surface plasmon resonance of silver nanoparticles while converting light into heat. The photoresponsive properties of nano-Ag/LCE nanocomposites were investigated with varying ilhunination intensities and silver nanoparticle doping concentrations（0.04% to 0.2%, mass fraction）. The nano-Ag/LCE nanocomposites show sensitive deformation under irradiation due to their excellent photothermal con- version efficiency, and this photostimulated muscle-like actuation is fully reversible via the on-off behavior of light. Incorporating silver nanoparticles into the LCE matrix also improves the mechanical properties and enhances the load-actuation capability of the material.展开更多
文摘目的探讨Wolf-Hirschhorn综合征(Wolf-Hirschhorn syndrome,WHS)胎儿的产前超声表型特征,并分析胎儿生长受限(fetal growth retardation,FGR)表型的关键区域。方法回顾2262例产前超声异常胎儿的染色体核型和染色体微阵列分析结果,总结WHS胎儿的产前超声表型特征及其4p缺失片段的差异,并结合文献报道的孤立性4p缺失的WHS病例,分析4p缺失片段的最小重叠区域(smallest region of overlap,SRO),以确定FGR表型的关键区域。结果在2262例超声异常胎儿中,共检出10例4p缺失的WHS。这10例胎儿均表现出FGR。结合文献报道的80例患者进行统计分析,结果显示WHS最常见的产前超声表型为FGR,占76.7%。对于FGR相关SRO的定位分析提示,4p16.3区1.32~1.74 Mb的位置存在一个SRO,其大小约419 kb,包含7个蛋白质编码基因:TACC3、SLBP、TMEM129、FAM53A、MAEA、UVSSA及CRIPAK。结论WHS胎儿最常见的产前超声表型为FGR。4p16.3区1.32~1.74 Mb的位置可能是FGR表型的关键区域,所包含的TACC3和SLBP可能是FGR的候选基因。
基金Supported by the National Natural Science Foundation of China（No.61275117）.
文摘We reported a nano-Ag/liquid crystalline elastomer（LCE） nanocomposite by incorporating silver nanopar- ticles into a monodomain polysiloxane-based LCE matrix via a novel experimental protocol. The photo-thermo- mechanical actuation of the LCE matrix was realized via the surface plasmon resonance of silver nanoparticles while converting light into heat. The photoresponsive properties of nano-Ag/LCE nanocomposites were investigated with varying ilhunination intensities and silver nanoparticle doping concentrations（0.04% to 0.2%, mass fraction）. The nano-Ag/LCE nanocomposites show sensitive deformation under irradiation due to their excellent photothermal con- version efficiency, and this photostimulated muscle-like actuation is fully reversible via the on-off behavior of light. Incorporating silver nanoparticles into the LCE matrix also improves the mechanical properties and enhances the load-actuation capability of the material.
