目的:评估空气填充联合内界膜翻转及自体血治疗伴有后巩膜葡萄肿的高度近视黄斑裂孔性视网膜脱离(MHRD)的疗效。方法:回顾性非对照研究分析高度近视眼MHRD患者的治疗效果。玻璃体切割术中使用曲安奈德染色清除玻璃体后皮质,内界膜翻转...目的:评估空气填充联合内界膜翻转及自体血治疗伴有后巩膜葡萄肿的高度近视黄斑裂孔性视网膜脱离(MHRD)的疗效。方法:回顾性非对照研究分析高度近视眼MHRD患者的治疗效果。玻璃体切割术中使用曲安奈德染色清除玻璃体后皮质,内界膜翻转后应用自体血固定翻转的内界膜后空气填充。记录术后黄斑裂孔闭合率、视网膜复位率及术后最佳矫正视力(BCVA)。结果:研究共纳入高度近视MHRD患者24例24眼。患者随访至少6mo,平均13.58±7.00mo。末次随访时21眼(88%)黄斑裂孔闭合,20眼(83%)视网膜复位。其中17眼(71%)黄斑裂孔闭合且视网膜复位,3眼(13%)黄斑裂孔未闭合但视网膜复位,4眼(17%)黄斑裂孔闭合但仍有视网膜下液。所有病例无需接受二次玻璃体切割手术。末次随访BCVA(LogMAR)较术前显著提高(0.65±0.34 vs 1.36±0.49,P<0.001)。12眼(50%)的BCVA提高大于等于2行。结论:玻璃体切割术联合内界膜翻转、自体血及空气填充是治疗高度近视眼MHRD的有效方法。展开更多
AIM:To evaluate the peripheral arterial filling time(PAFT)and venous filling time(VFT)in eyes without known diseases that may influence filling process using ultra-widefield(UWF)fluorescein angiography(FA),and to revi...AIM:To evaluate the peripheral arterial filling time(PAFT)and venous filling time(VFT)in eyes without known diseases that may influence filling process using ultra-widefield(UWF)fluorescein angiography(FA),and to review the peripheral retina fluorescence features.METHODS:A total of 30 eyes of 30 patients were retrospectively reviewed in this observational study.UWFFA was performed using Optos 200Tx.PAFT and VFT was recorded.The interval between the arterial or venous filling completion and the previous photo was documented.The appearance of the far peripheral retina was described as either granular background fluorescence or mottled fluorescent band or vascular leakage.Terminal vascular patterns was described as loop pattern or branching pattern.Microvascular abnormalities such as arteriovenous shunting,vessels crossing the horizontal raphe,right angle vessels,terminal networks,capillary nonperfusion,drusen or microaneurysms were evaluated.RESULTS:The normal limits of PAFT was 3.397-8.984s and 4.399-11.753s for VFT.The appearance of the far peripheral retina,defined as granular background(63%),mottled fluorescence(20%),or vascular leakage(17%),was symmetrical between both eyes.Capillary nonperfusion(23%)and microaneurysms(40%)were more frequently found in eyes with loop pattern than in eyes with branching pattern.Other peripheral signs such as right-angle vessels(73%),and terminal networks(80%)were commonly seen on UWF-FA in the normal peripheral retina.CONCLUSION:The main courses of retinal artery and vein filling time are overlapping with each other on UWF-FA.Notably,the arterial filling process is completed in the arteriovenous phase rather than the traditionally named arterial phase.There are various manifestations in the peripheral retina of normal eyes.展开更多
文摘目的:评估空气填充联合内界膜翻转及自体血治疗伴有后巩膜葡萄肿的高度近视黄斑裂孔性视网膜脱离(MHRD)的疗效。方法:回顾性非对照研究分析高度近视眼MHRD患者的治疗效果。玻璃体切割术中使用曲安奈德染色清除玻璃体后皮质,内界膜翻转后应用自体血固定翻转的内界膜后空气填充。记录术后黄斑裂孔闭合率、视网膜复位率及术后最佳矫正视力(BCVA)。结果:研究共纳入高度近视MHRD患者24例24眼。患者随访至少6mo,平均13.58±7.00mo。末次随访时21眼(88%)黄斑裂孔闭合,20眼(83%)视网膜复位。其中17眼(71%)黄斑裂孔闭合且视网膜复位,3眼(13%)黄斑裂孔未闭合但视网膜复位,4眼(17%)黄斑裂孔闭合但仍有视网膜下液。所有病例无需接受二次玻璃体切割手术。末次随访BCVA(LogMAR)较术前显著提高(0.65±0.34 vs 1.36±0.49,P<0.001)。12眼(50%)的BCVA提高大于等于2行。结论:玻璃体切割术联合内界膜翻转、自体血及空气填充是治疗高度近视眼MHRD的有效方法。
基金Supported by Capital Health Development Research Special Fund(No.2020-2-2053)。
文摘AIM:To evaluate the peripheral arterial filling time(PAFT)and venous filling time(VFT)in eyes without known diseases that may influence filling process using ultra-widefield(UWF)fluorescein angiography(FA),and to review the peripheral retina fluorescence features.METHODS:A total of 30 eyes of 30 patients were retrospectively reviewed in this observational study.UWFFA was performed using Optos 200Tx.PAFT and VFT was recorded.The interval between the arterial or venous filling completion and the previous photo was documented.The appearance of the far peripheral retina was described as either granular background fluorescence or mottled fluorescent band or vascular leakage.Terminal vascular patterns was described as loop pattern or branching pattern.Microvascular abnormalities such as arteriovenous shunting,vessels crossing the horizontal raphe,right angle vessels,terminal networks,capillary nonperfusion,drusen or microaneurysms were evaluated.RESULTS:The normal limits of PAFT was 3.397-8.984s and 4.399-11.753s for VFT.The appearance of the far peripheral retina,defined as granular background(63%),mottled fluorescence(20%),or vascular leakage(17%),was symmetrical between both eyes.Capillary nonperfusion(23%)and microaneurysms(40%)were more frequently found in eyes with loop pattern than in eyes with branching pattern.Other peripheral signs such as right-angle vessels(73%),and terminal networks(80%)were commonly seen on UWF-FA in the normal peripheral retina.CONCLUSION:The main courses of retinal artery and vein filling time are overlapping with each other on UWF-FA.Notably,the arterial filling process is completed in the arteriovenous phase rather than the traditionally named arterial phase.There are various manifestations in the peripheral retina of normal eyes.
