Taking the knowledge points of hotel construction site selection as an example,this paper integrated the information-based teaching method with traditional classrooms.With the aid of virtual reality(VR)technology,the ...Taking the knowledge points of hotel construction site selection as an example,this paper integrated the information-based teaching method with traditional classrooms.With the aid of virtual reality(VR)technology,the information-based teaching can turn the abstract knowledge into vivid knowledge.Using the Rain Classroom platform,teachers can communicate with students in a better manner.Combined with the powerful spatial data analysis function of geographic information system(GIS)software,it is intended to provide new ideas and perspectives for the effective integration of traditional teaching classrooms and information technology,and effectively apply them to the practical teaching process.展开更多
Three-dimensional(3D)hydrogel models play a crucial role in tissue engineering for promoting tissue regeneration.A biomimetic microchannel network system in the 3D hydrogel model is necessary for optimal cellular func...Three-dimensional(3D)hydrogel models play a crucial role in tissue engineering for promoting tissue regeneration.A biomimetic microchannel network system in the 3D hydrogel model is necessary for optimal cellular function.This report describes the preparation of a biomimetic hydrogel scaffold with an internal microchannel network,using electrospinning techniques and the sacrificial template method for 3D cell culture.Microchannels and cavities were created within the gelatin methacryloyl(GelMA)hydrogel by sacrificing polyvinyl alcohol(PVA)electrospun fibers(>10µm),resulting in the creation of microvessel-like channels.Mechanical characterizations,swelling properties,and biodegradation analysis were conducted to investigate the feasibility of a biomimetic microchannel network hydrogel scaffold for 3D cell culture applications.Compared to pure GelMA hydrogel,the hydrogel with microchannels promoted cell proliferation,adhesion,and endothelial tube formation.Moreover,the results confirmed that the biomimetic microchannel network scaffold had a major impact on the distribution and arrangement of human umbilical vein endothelial cells(HUVECs)and can enable the formation of artificial microvasculature by the culture of HUVECs and cell media perfusion.展开更多
文摘Taking the knowledge points of hotel construction site selection as an example,this paper integrated the information-based teaching method with traditional classrooms.With the aid of virtual reality(VR)technology,the information-based teaching can turn the abstract knowledge into vivid knowledge.Using the Rain Classroom platform,teachers can communicate with students in a better manner.Combined with the powerful spatial data analysis function of geographic information system(GIS)software,it is intended to provide new ideas and perspectives for the effective integration of traditional teaching classrooms and information technology,and effectively apply them to the practical teaching process.
基金supported by the National Natural Science Foundation of China(No.31870934)the Natural Science Foundation for Young Scientists of Shanxi Province(No.202103021223100),China.
文摘Three-dimensional(3D)hydrogel models play a crucial role in tissue engineering for promoting tissue regeneration.A biomimetic microchannel network system in the 3D hydrogel model is necessary for optimal cellular function.This report describes the preparation of a biomimetic hydrogel scaffold with an internal microchannel network,using electrospinning techniques and the sacrificial template method for 3D cell culture.Microchannels and cavities were created within the gelatin methacryloyl(GelMA)hydrogel by sacrificing polyvinyl alcohol(PVA)electrospun fibers(>10µm),resulting in the creation of microvessel-like channels.Mechanical characterizations,swelling properties,and biodegradation analysis were conducted to investigate the feasibility of a biomimetic microchannel network hydrogel scaffold for 3D cell culture applications.Compared to pure GelMA hydrogel,the hydrogel with microchannels promoted cell proliferation,adhesion,and endothelial tube formation.Moreover,the results confirmed that the biomimetic microchannel network scaffold had a major impact on the distribution and arrangement of human umbilical vein endothelial cells(HUVECs)and can enable the formation of artificial microvasculature by the culture of HUVECs and cell media perfusion.
