Introduction: The impact of pregnancy on the prognosis of papillary thyroid carcinoma (PTC) has been debated for several decades;however, no definitive conclusions have been reached. The main objective of this study i...Introduction: The impact of pregnancy on the prognosis of papillary thyroid carcinoma (PTC) has been debated for several decades;however, no definitive conclusions have been reached. The main objective of this study is to demonstrate the short-term influence of pregnancy on the evolution and prognosis of PTC. Materials and Methods: A prospective descriptive and analytical study was conducted in the Endocrinology and Diabetology Department at the Hassan II University Hospital in Fez, including patients followed for papillary thyroid carcinoma presenting with a pregnancy during the year 2019 and 2020. The follow-up of these patients was continued until 1 year postpartum. We studied the clinical, paraclinical and therapeutic factors that could influence the prognosis of the disease. Results: We included 26 patients. Our study showed a significant correlation between recurrence and the presence of unfavorable histological signs (p = 0.02) as well as the initial Tg level (0.01). However, pregnancy was not an influencing factor (p = 0.41). Conclusion: Pregnancy does not seem to be a factor aggravating the prognosis of differentiated thyroid cancers.展开更多
Thyroid diseases are common in women of childbearing age.Different factors of maternal thyroid function occur during pregnancy;therefore,guidelines recommend trimester-specific pregnancy reference range for thyroid-st...Thyroid diseases are common in women of childbearing age.Different factors of maternal thyroid function occur during pregnancy;therefore,guidelines recommend trimester-specific pregnancy reference range for thyroid-stimulating hormone.Manifestly,thyroid dysfunctions have deleterious obstetrical and neonatal outcomes.Therefore,an adequate treatment is important to prevent adverse pregnancy complications.Furthermore,iodine deficiency during pregnancy could originate maternal and fetal problems.Consequently,scientific organizations recommend prenatal iodine supplementation for all pregnant women.However,treatment of thyroid autoimmunity is intriguing,but adequately powered randomized controlled trials are needed.The aim of this article was to summarize the reported results of the literature related to the management of thyroid disease during pregnancy in order to help endocrinologists in decision-making processes.展开更多
文摘Introduction: The impact of pregnancy on the prognosis of papillary thyroid carcinoma (PTC) has been debated for several decades;however, no definitive conclusions have been reached. The main objective of this study is to demonstrate the short-term influence of pregnancy on the evolution and prognosis of PTC. Materials and Methods: A prospective descriptive and analytical study was conducted in the Endocrinology and Diabetology Department at the Hassan II University Hospital in Fez, including patients followed for papillary thyroid carcinoma presenting with a pregnancy during the year 2019 and 2020. The follow-up of these patients was continued until 1 year postpartum. We studied the clinical, paraclinical and therapeutic factors that could influence the prognosis of the disease. Results: We included 26 patients. Our study showed a significant correlation between recurrence and the presence of unfavorable histological signs (p = 0.02) as well as the initial Tg level (0.01). However, pregnancy was not an influencing factor (p = 0.41). Conclusion: Pregnancy does not seem to be a factor aggravating the prognosis of differentiated thyroid cancers.
文摘Thyroid diseases are common in women of childbearing age.Different factors of maternal thyroid function occur during pregnancy;therefore,guidelines recommend trimester-specific pregnancy reference range for thyroid-stimulating hormone.Manifestly,thyroid dysfunctions have deleterious obstetrical and neonatal outcomes.Therefore,an adequate treatment is important to prevent adverse pregnancy complications.Furthermore,iodine deficiency during pregnancy could originate maternal and fetal problems.Consequently,scientific organizations recommend prenatal iodine supplementation for all pregnant women.However,treatment of thyroid autoimmunity is intriguing,but adequately powered randomized controlled trials are needed.The aim of this article was to summarize the reported results of the literature related to the management of thyroid disease during pregnancy in order to help endocrinologists in decision-making processes.
