目的探究最好自我(best possible self,BPS)训练对集训期新兵心理健康状况(乐观与悲观情绪、知觉压力和主观幸福感)的干预效果。方法采用非随机对照试验设计方案,以整群抽样法于2023年9月在某新兵训练基地抽取212名新兵,根据建制分为研...目的探究最好自我(best possible self,BPS)训练对集训期新兵心理健康状况(乐观与悲观情绪、知觉压力和主观幸福感)的干预效果。方法采用非随机对照试验设计方案,以整群抽样法于2023年9月在某新兵训练基地抽取212名新兵,根据建制分为研究组(100人,行BPS训练15 min/d)和对照组[112人,行日常生活(typical day,TD)表象训练,15 min/d],连续干预2周。于干预当天(T0),干预实施1周(T1)、2周(T2),干预结束后1周(T3)采用未来预期量表(Future Expectation Scale,FEX)、知觉压力量表(Chinese Perceived Stress Scale,CPSS)、正负性情绪量表(Positive and Negative Affect Scale,PANAS)和生活满意度量表(Satisfaction with Life Scale,SWLS)对2组被试进行测量,评估BPS训练对上述心理健康指标的训练效果。结果2组被试的人口统计学信息及各心理学基线指标均衡。随着训练的进行,2组在悲观情绪、知觉压力和主观幸福感(包含情感和认知幸福感)上的训练效果表现出明显的差异(P<0.05)。研究组T1~T3的悲观情绪相比基线(T0)明显降低(P<0.01),情感幸福感(P<0.01)和认知幸福感(P<0.01)明显升高,其知觉压力在T1(P<0.05)和T3(P<0.01)也明显降低;而对照组在训练前后却无上述明显变化。结论2周BPS训练可有效降低集训期新兵悲观情绪和知觉压力水平,提升其主观幸福感,促进新兵心理健康。展开更多
Identification of stratigraphic interfaces and lithology is a key aspect in geological and geotechnical investigations.In this study,a monitoring while-drilling system was developed,along with a corresponding data pre...Identification of stratigraphic interfaces and lithology is a key aspect in geological and geotechnical investigations.In this study,a monitoring while-drilling system was developed,along with a corresponding data pre-processing method.The method can handle invalid drilling data generated during manual operations.The correlation between various drilling parameters was analyzed,and a database of stratigraphic interfaces and key lithology identification based on the monitoring parameters was established.The average drilling speed was found to be the most suitable parameter for stratigraphic and lithology identification,and when the average drilling speed varied over a wide range,it corresponded to a stratigraphic interface.The average drilling speeds in sandy mudstone and sandstone strata were in the ranges of 0.1e0.2 m/min and 0.2e0.29 m/min,respectively.The results obtained using the present method were consistent with geotechnical survey results.The proposed method can be used for realtime lithology identification and represents a novel approach for intelligent geotechnical surveying.展开更多
Alveolar echinococcosis(AE)is a lethal parasitic disease caused by Echinococcus multilocularis larvae,and more than 90%of pri-mary AE lesions occur in the liver.Most of the affected individ-uals remain asymptomatic an...Alveolar echinococcosis(AE)is a lethal parasitic disease caused by Echinococcus multilocularis larvae,and more than 90%of pri-mary AE lesions occur in the liver.Most of the affected individ-uals remain asymptomatic and the disease is often diagnosed at an advanced stage.The infection may spread to organs adjacent to the liver or distant locations,eventually causing end-stage multi-ple organ AE.Brain metastasis of AE is the most fatal with an inci-dence rate of 0.2%[1].展开更多
BACKGROUND The optimal approach for managing hepatic hemangioma is controversial.AIM To evaluate a clinical grading system for management of hepatic hemangioma based on our 17-year of single institution experience.MET...BACKGROUND The optimal approach for managing hepatic hemangioma is controversial.AIM To evaluate a clinical grading system for management of hepatic hemangioma based on our 17-year of single institution experience.METHODS A clinical grading system was retrospectively applied to 1171 patients with hepatic hemangioma from January 2002 to December 2018.Patients were classified into four groups based on the clinical grading system and treatment:(1)Observation group with score<4(Obs score<4);(2)Surgical group with score<4(Sur score<4);(3)Observation group with score≥4(Obs score≥4);and(4)Surgical group with score≥4(Sur score≥4).The clinico-pathological index and outcomes were evaluated.RESULTS There were significantly fewer symptomatic patients in surgical groups(Sur score≥4 vs Obs score≥4,P<0.001;Sur score<4 vs Obs score<4,χ^(2)=8.60,P=0.004;Sur score≥4 vs Obs score<4,P<0.001).The patients in Sur score≥4 had a lower rate of in need for intervention and total patients with adverse event than in Obs score≥4(P<0.001;P<0.001).Nevertheless,there was no significant difference in need for intervention and total patients with adverse event between the Sur score<4 and Obs score<4(P>0.05;χ^(2)=1.68,P>0.05).CONCLUSION This clinical grading system appeared as a practical tool for hepatic hemangioma.Surgery can be suggested for patients with a score≥4.For those with<4,follow-up should be proposed.展开更多
为挖掘特征间的语义关系以及空间分布信息,并通过多特征增强进一步改善点云语义分割的效果,提出一种基于多特征融合的点云场景语义分割网络(MFF-Net)。所提网络以点的三维坐标和改进后的边特征作为输入,首先,利用K-近邻(KNN)算法搜寻点...为挖掘特征间的语义关系以及空间分布信息,并通过多特征增强进一步改善点云语义分割的效果,提出一种基于多特征融合的点云场景语义分割网络(MFF-Net)。所提网络以点的三维坐标和改进后的边特征作为输入,首先,利用K-近邻(KNN)算法搜寻点的近邻点,并在三维坐标和近邻点间坐标差值的基础上计算几何偏移量,从而增强点的局部几何特征表示;其次,将中心点与近邻点间的距离作为权重信息更新边特征,并引入空间注意力机制,获取特征间的语义信息;再次,通过计算近邻特征间的差值,利用均值池化操作进一步提取特征间的空间分布信息;最后,利用注意力池化操作融合三边特征。实验结果表明,所提网络在S3DIS(Stanford 3D large-scale Indoor Spaces)数据集上的平均交并比(mIoU)达到了67.5%,总体准确率(OA)达到了87.2%,相较于PointNet++分别提高10.2和3.4个百分点,可见MFF-Net在大型室内/室外场景均能获得良好的分割效果。展开更多
Proanthocyanidin(PA)is an important bioactive compound with multiple physiological benefits in jujube(Ziziphus jujube Mill.).However,the molecular mechanisms underlying PA biosynthesis in jujube fruit have not been in...Proanthocyanidin(PA)is an important bioactive compound with multiple physiological benefits in jujube(Ziziphus jujube Mill.).However,the molecular mechanisms underlying PA biosynthesis in jujube fruit have not been investigated.Here,the profiling of PA,(+)-catechin and(–)-epicatechin and transcriptome sequencing of three jujube cultivars from Xinjiang Uyghur Autonomous Region of China at five developmental stages were analyzed.The levels of total PAs and catechin exhibited a decreased trend over jujube ripening,and epicatechin content of two jujube cultivars increased first and then declined.Transcriptome analysis revealed that the differentially expressed genes(DEGs)were mainly enriched in ribosome,glycolysis/gluconeogenesis,fructose and mannose metabolism.17 DEGs encoding PAL,CHS,CHI,CHS,F3'H,LAR,ANR,C4Hs,4CLs,FLSs,DFRs and UFGTs involved in PA biosynthesis were relatively abundant.The highly transcribed LAR gene may greatly contribute to epicatechin accumulation.A weighted gene co-expression network analysis(WGCNA)was performed,and a network module including 1620 genes highly correlated with content of Pas and catechin was established.We identified 58 genes including 9 structural genes and 49 regulatory genes related to PA biosynthesis and regulation in the WGCNA module.Sixteen genes encoding 9 families of transcriptional factors(i.e.,MYB,bHLH,ERF,bZIP,NAC,SBP,MIKC,HB,WRKY)were considered as hub genes.The results of qRT-PCR analysis validating 10 genes were well consistent with the transcriptome data.These findings provide valuable knowledge to facilitate its genetic studies and molecular breeding.展开更多
The dissociation of water is the rate-determining step of several energy-relating reactions due to high energy barrier in homolysis of H-O bond.Herein,engineering vacancy-atom ensembles via injecting oxygen vacancy(V ...The dissociation of water is the rate-determining step of several energy-relating reactions due to high energy barrier in homolysis of H-O bond.Herein,engineering vacancy-atom ensembles via injecting oxygen vacancy(V O)into single facet-exposed TiO_(2)-Pd catalyst to form V_(O)-Pd ensemble is proposed and implemented.The outstanding activity of as-prepared catalyst,1.5-PdTV_(O),toward water dissociation is established with a turnover frequency of 240 min^(−1) in ammonia borane hydrolysis at 298 K.Density functional theory simulation suggests that the V_(O)-Pd ensemble is responsible for the high intrinsic catalytic activity.Water molecules tend to be dissociated on V_(O) sites and ammonia borane molecules on Pd atoms.Those H atoms from water dissociation on V_(O) combine with H atoms from ammonia borane on Pd atoms to generate H_(2).This insights into engineering vacancy-atom ensembles catalysis provide a new avenue to design catalytic materials for important energy chemical reactions.展开更多
BACKGROUND Ex vivo liver resection and autotransplantation(ELRA)is an essential approach for treating patients with end-stage hepatic alveolar echinococcosis(AE),and its surgical indications involve severe invasion of...BACKGROUND Ex vivo liver resection and autotransplantation(ELRA)is an essential approach for treating patients with end-stage hepatic alveolar echinococcosis(AE),and its surgical indications involve severe invasion of important hepatic vessels,which makes in vivo resection impossible.Revascularization is a major step in the process of ELRA,which is extremely challenging when the invaded vessels have huge defects.CASE SUMMARY Herein,we have reported the case of a 26-year-old patient with hepatic AE in an autologous liver graft who underwent complex inferior vena cava(IVC)reconstruction using disease-free IVC,autologous portal vein fragments,and umbilical vein within the ligamentum teres hepatis.The patient showed good surgical recovery without vascular-related complications during the long-term follow-up.CONCLUSION We reviewed three studies that have reported complex revascularization of the IVC.This case report and systematic review showed that the use of autologous perihepatic vessels prevents donor-area trauma,immune rejection,and other adverse reactions.When the blood vessel is severely invaded and a single vascular material cannot repair and reconstruct the defect,ELRA may provide a safe and feasible surgical approach,which has good prospects for clinical application.展开更多
文摘目的探究最好自我(best possible self,BPS)训练对集训期新兵心理健康状况(乐观与悲观情绪、知觉压力和主观幸福感)的干预效果。方法采用非随机对照试验设计方案,以整群抽样法于2023年9月在某新兵训练基地抽取212名新兵,根据建制分为研究组(100人,行BPS训练15 min/d)和对照组[112人,行日常生活(typical day,TD)表象训练,15 min/d],连续干预2周。于干预当天(T0),干预实施1周(T1)、2周(T2),干预结束后1周(T3)采用未来预期量表(Future Expectation Scale,FEX)、知觉压力量表(Chinese Perceived Stress Scale,CPSS)、正负性情绪量表(Positive and Negative Affect Scale,PANAS)和生活满意度量表(Satisfaction with Life Scale,SWLS)对2组被试进行测量,评估BPS训练对上述心理健康指标的训练效果。结果2组被试的人口统计学信息及各心理学基线指标均衡。随着训练的进行,2组在悲观情绪、知觉压力和主观幸福感(包含情感和认知幸福感)上的训练效果表现出明显的差异(P<0.05)。研究组T1~T3的悲观情绪相比基线(T0)明显降低(P<0.01),情感幸福感(P<0.01)和认知幸福感(P<0.01)明显升高,其知觉压力在T1(P<0.05)和T3(P<0.01)也明显降低;而对照组在训练前后却无上述明显变化。结论2周BPS训练可有效降低集训期新兵悲观情绪和知觉压力水平,提升其主观幸福感,促进新兵心理健康。
文摘Identification of stratigraphic interfaces and lithology is a key aspect in geological and geotechnical investigations.In this study,a monitoring while-drilling system was developed,along with a corresponding data pre-processing method.The method can handle invalid drilling data generated during manual operations.The correlation between various drilling parameters was analyzed,and a database of stratigraphic interfaces and key lithology identification based on the monitoring parameters was established.The average drilling speed was found to be the most suitable parameter for stratigraphic and lithology identification,and when the average drilling speed varied over a wide range,it corresponded to a stratigraphic interface.The average drilling speeds in sandy mudstone and sandstone strata were in the ranges of 0.1e0.2 m/min and 0.2e0.29 m/min,respectively.The results obtained using the present method were consistent with geotechnical survey results.The proposed method can be used for realtime lithology identification and represents a novel approach for intelligent geotechnical surveying.
基金This study was supported by the grants from the National Natural Science Foundation of China(81960377)Open Project of State Key Laboratory of Pathogenesis,Prevention and Treatment of High Incidence Diseases in Central Asia(SKL-HIDCA-2020-BC and SKL-HIDCA-2021-4)Xinjiang Uygur Autonomous Region University Scientific Research Project(XJEDU2021I016).
文摘Alveolar echinococcosis(AE)is a lethal parasitic disease caused by Echinococcus multilocularis larvae,and more than 90%of pri-mary AE lesions occur in the liver.Most of the affected individ-uals remain asymptomatic and the disease is often diagnosed at an advanced stage.The infection may spread to organs adjacent to the liver or distant locations,eventually causing end-stage multi-ple organ AE.Brain metastasis of AE is the most fatal with an inci-dence rate of 0.2%[1].
文摘BACKGROUND The optimal approach for managing hepatic hemangioma is controversial.AIM To evaluate a clinical grading system for management of hepatic hemangioma based on our 17-year of single institution experience.METHODS A clinical grading system was retrospectively applied to 1171 patients with hepatic hemangioma from January 2002 to December 2018.Patients were classified into four groups based on the clinical grading system and treatment:(1)Observation group with score<4(Obs score<4);(2)Surgical group with score<4(Sur score<4);(3)Observation group with score≥4(Obs score≥4);and(4)Surgical group with score≥4(Sur score≥4).The clinico-pathological index and outcomes were evaluated.RESULTS There were significantly fewer symptomatic patients in surgical groups(Sur score≥4 vs Obs score≥4,P<0.001;Sur score<4 vs Obs score<4,χ^(2)=8.60,P=0.004;Sur score≥4 vs Obs score<4,P<0.001).The patients in Sur score≥4 had a lower rate of in need for intervention and total patients with adverse event than in Obs score≥4(P<0.001;P<0.001).Nevertheless,there was no significant difference in need for intervention and total patients with adverse event between the Sur score<4 and Obs score<4(P>0.05;χ^(2)=1.68,P>0.05).CONCLUSION This clinical grading system appeared as a practical tool for hepatic hemangioma.Surgery can be suggested for patients with a score≥4.For those with<4,follow-up should be proposed.
文摘为挖掘特征间的语义关系以及空间分布信息,并通过多特征增强进一步改善点云语义分割的效果,提出一种基于多特征融合的点云场景语义分割网络(MFF-Net)。所提网络以点的三维坐标和改进后的边特征作为输入,首先,利用K-近邻(KNN)算法搜寻点的近邻点,并在三维坐标和近邻点间坐标差值的基础上计算几何偏移量,从而增强点的局部几何特征表示;其次,将中心点与近邻点间的距离作为权重信息更新边特征,并引入空间注意力机制,获取特征间的语义信息;再次,通过计算近邻特征间的差值,利用均值池化操作进一步提取特征间的空间分布信息;最后,利用注意力池化操作融合三边特征。实验结果表明,所提网络在S3DIS(Stanford 3D large-scale Indoor Spaces)数据集上的平均交并比(mIoU)达到了67.5%,总体准确率(OA)达到了87.2%,相较于PointNet++分别提高10.2和3.4个百分点,可见MFF-Net在大型室内/室外场景均能获得良好的分割效果。
基金supported by Major scientific and technological projects of Xinjiang Production and Construction Corps(2017DB006 and 2020KWZ-012)。
文摘Proanthocyanidin(PA)is an important bioactive compound with multiple physiological benefits in jujube(Ziziphus jujube Mill.).However,the molecular mechanisms underlying PA biosynthesis in jujube fruit have not been investigated.Here,the profiling of PA,(+)-catechin and(–)-epicatechin and transcriptome sequencing of three jujube cultivars from Xinjiang Uyghur Autonomous Region of China at five developmental stages were analyzed.The levels of total PAs and catechin exhibited a decreased trend over jujube ripening,and epicatechin content of two jujube cultivars increased first and then declined.Transcriptome analysis revealed that the differentially expressed genes(DEGs)were mainly enriched in ribosome,glycolysis/gluconeogenesis,fructose and mannose metabolism.17 DEGs encoding PAL,CHS,CHI,CHS,F3'H,LAR,ANR,C4Hs,4CLs,FLSs,DFRs and UFGTs involved in PA biosynthesis were relatively abundant.The highly transcribed LAR gene may greatly contribute to epicatechin accumulation.A weighted gene co-expression network analysis(WGCNA)was performed,and a network module including 1620 genes highly correlated with content of Pas and catechin was established.We identified 58 genes including 9 structural genes and 49 regulatory genes related to PA biosynthesis and regulation in the WGCNA module.Sixteen genes encoding 9 families of transcriptional factors(i.e.,MYB,bHLH,ERF,bZIP,NAC,SBP,MIKC,HB,WRKY)were considered as hub genes.The results of qRT-PCR analysis validating 10 genes were well consistent with the transcriptome data.These findings provide valuable knowledge to facilitate its genetic studies and molecular breeding.
基金This work was supported by the National Natural Science Foundation of China (Nos.11874328,22075254).
文摘The dissociation of water is the rate-determining step of several energy-relating reactions due to high energy barrier in homolysis of H-O bond.Herein,engineering vacancy-atom ensembles via injecting oxygen vacancy(V O)into single facet-exposed TiO_(2)-Pd catalyst to form V_(O)-Pd ensemble is proposed and implemented.The outstanding activity of as-prepared catalyst,1.5-PdTV_(O),toward water dissociation is established with a turnover frequency of 240 min^(−1) in ammonia borane hydrolysis at 298 K.Density functional theory simulation suggests that the V_(O)-Pd ensemble is responsible for the high intrinsic catalytic activity.Water molecules tend to be dissociated on V_(O) sites and ammonia borane molecules on Pd atoms.Those H atoms from water dissociation on V_(O) combine with H atoms from ammonia borane on Pd atoms to generate H_(2).This insights into engineering vacancy-atom ensembles catalysis provide a new avenue to design catalytic materials for important energy chemical reactions.
基金Supported by Key Laboratory Opening Topic Fund Subsidization:The Regulation of Sympathetic Nerve in Liver Regeneration in Hepatic Alveolar Echinococcosis,No.2021D04024.
文摘BACKGROUND Ex vivo liver resection and autotransplantation(ELRA)is an essential approach for treating patients with end-stage hepatic alveolar echinococcosis(AE),and its surgical indications involve severe invasion of important hepatic vessels,which makes in vivo resection impossible.Revascularization is a major step in the process of ELRA,which is extremely challenging when the invaded vessels have huge defects.CASE SUMMARY Herein,we have reported the case of a 26-year-old patient with hepatic AE in an autologous liver graft who underwent complex inferior vena cava(IVC)reconstruction using disease-free IVC,autologous portal vein fragments,and umbilical vein within the ligamentum teres hepatis.The patient showed good surgical recovery without vascular-related complications during the long-term follow-up.CONCLUSION We reviewed three studies that have reported complex revascularization of the IVC.This case report and systematic review showed that the use of autologous perihepatic vessels prevents donor-area trauma,immune rejection,and other adverse reactions.When the blood vessel is severely invaded and a single vascular material cannot repair and reconstruct the defect,ELRA may provide a safe and feasible surgical approach,which has good prospects for clinical application.
