The pan-Arctic is confronted with air pollution transported from lower latitudes.Observations have shown that aerosols help increase plant photosynthesis through the diffuse radiation fertilization effects(DRFEs).Whil...The pan-Arctic is confronted with air pollution transported from lower latitudes.Observations have shown that aerosols help increase plant photosynthesis through the diffuse radiation fertilization effects(DRFEs).While such DRFEs have been explored at low to middle latitudes,the aerosol impacts on pan-Arctic ecosystems and the contributions by anthropogenic and natural emission sources remain less quantified.Here,we perform regional simulations at 0.2o×0.2ousing a well-validated vegetation model(Yale Interactive terrestrial Biosphere,YIBs)in combination with multi-source of observations to quantify the impacts of aerosol DRFEs on the net primary productivity(NPP)in the pan-Arctic during 2001-19.Results show that aerosol DRFEs increase pan-Arctic NPP by 2.19 Pg C(12.8%)yr^(-1)under clear-sky conditions,in which natural and anthropogenic sources contribute to 8.9% and 3.9%,respectively.Under all-sky conditions,such DRFEs are largely dampened by cloud to only 0.26 Pg C(1.24%)yr^(-1),with contributions of 0.65% by natural and 0.59% by anthropogenic species.Natural aerosols cause a positive NPP trend of 0.022% yr^(-1)following the increased fire activities in the pan-Arctic.In contrast,anthropogenic aerosols induce a negative trend of-0.01% yr^(-1)due to reduced emissions from the middle latitudes.Such trends in aerosol DRFEs show a turning point in the year of 2007 with more positive NPP trends by natural aerosols but negative NPP trends by anthropogenic aerosols thereafter.Though affected by modeling uncertainties,this study suggests a likely increasing impact of aerosols on terrestrial ecosystems in the pan-Arctic under global warming.展开更多
High-temperature treatment is key to the preparation of zeolite catalysts.Herein,the effects of hightemperature treatment on the property and performance of HZSM-5 zeolites were studied in this work.X-Ray diffraction,...High-temperature treatment is key to the preparation of zeolite catalysts.Herein,the effects of hightemperature treatment on the property and performance of HZSM-5 zeolites were studied in this work.X-Ray diffraction,N2physisorption,27Al magic angle spinning nuclear magnetic resonance(MAS NMR),and temperature-programmed desorption of ammonia results indicated that the hightemperature treatment at 650℃ hardly affected the inherent crystal and texture of HZSM-5zeolites but facilitated the conversion of framework Al to extra-framework Al,reducing the acid site and enhancing the acid strength.Moreover,the high-temperature treatment improved the performance of HZSM-5 zeolites in n-heptane catalytic cracking,promoting the conversion and light olefins yield while inhibiting coke formation.Based on the kinetic and mechanism analysis,the improvement of HZSM-5 performance caused by high-temperature treatment has been attributed to the formation of extra-framework Al,which enhanced the acid strength,facilitated the bimolecular reaction,and promoted the entropy change to overcome a higher energy barrier in n-heptane catalytic cracking.展开更多
Lightweight thin-walled structures with lattice infill are widely desired in satellite for their high stiffness-to-weight ratio and superior buckling strength resulting fromthe sandwich effect.Such structures can be f...Lightweight thin-walled structures with lattice infill are widely desired in satellite for their high stiffness-to-weight ratio and superior buckling strength resulting fromthe sandwich effect.Such structures can be fabricated bymetallic additive manufacturing technique,such as selective laser melting(SLM).However,the maximum dimensions of actual structures are usually in a sub-meter scale,which results in restrictions on their appliance in aerospace and other fields.In this work,a meter-scale thin-walled structure with lattice infill is designed for the fuel tank supporting component of the satellite by integrating a self-supporting lattice into the thickness optimization of the thin-wall.The designed structure is fabricated by SLM of AlSi10Mg and cold metal transfer welding technique.Quasi-static mechanical tests and vibration tests are both conducted to verify the mechanical strength of the designed large-scale lattice thin-walled structure.The experimental results indicate that themeter-scale thin-walled structure with lattice infill could meet the dimension and lightweight requirements of most spacecrafts.展开更多
Carnivorous plants,for instance,Dionaea muscipula and Nepenthes pitcher plant,inspired the innovation of advanced stimuli-responsive actuators and lubricant-infused slippery surfaces,respectively.However,hybrid bionic...Carnivorous plants,for instance,Dionaea muscipula and Nepenthes pitcher plant,inspired the innovation of advanced stimuli-responsive actuators and lubricant-infused slippery surfaces,respectively.However,hybrid bionic devices that combine the active and passive prey trapping capabilities of the two kinds of carnivorous plants remain a challenge.Herein,we report a moisture responsive shape-morphing slippery surface that enables both moisture responsive shapemorphing and oil-lubricated water repellency for simultaneous active-and passive-droplet manipulation.The moisture deformable slippery surface is prepared by creating biomimetic microstructures on graphene oxide(GO)membrane via femtosecond laser direct writing and subsequent lubricating with a thin layer of oil on the laser structured reduced GO(LRGO)surface.The integration of a lubricant-infused slippery surface with an LRGO/GO bilayer actuator endows the actuator with droplet sliding ability and promotes the moisture deformation performance due to oil-enhanced water repellency of the inert layer(LRGO).Based on the shape-morphing slippery surface,we prepared a series of proof-of-concept actuators,including a moisture-response Dionaea muscipula actuator,a smart frog tongue,and a smart flower,demonstrating their versatility for active/passive trapping,droplet manipulation,and sensing.展开更多
Globally,the efficient utilization of polymer wastes is one of the most important issues for current sustainable development topics.Herein,a green and efficient low-temperature combustion approach is proposed to deal ...Globally,the efficient utilization of polymer wastes is one of the most important issues for current sustainable development topics.Herein,a green and efficient low-temperature combustion approach is proposed to deal with polymer wastes and recover heat energy,simultaneously alleviating the environment and energy crisis.Non-noble metal oxides(Al_(2)O_(3),Fe_(2)O_(3),NiO_(2),ZrO_(2),La_(2)O_(3)and CeO_(2)) were prepared,characterized and screened to boost the low-temperature combustion of polyethylene waste at 300℃ in air.The mass change,heat release and CO_(x) formation were studied in details and employed to evaluate the combustion rate and efficiency.It was found that CeO_(2)significantly enhanced the combustion rate and efficiency,which was respectively 2 and 7 times that of non-catalytic case.An interesting phenomenon was observed that the catalytic performance of CeO_(2) in polyethylene low-temperature combustion was significantly improved by the 7-day storage in the room environment or water treatment.XPS analysis confirmed the co-existence of Ce^(3+) and Ce^(4+) in CeO_(2),and the 7-day storage and water treatment promoted the amount of Ce^(3+),which facilitated the formation of the oxygen vacancies.That may be the reason why CeO_(2) exhibited excellent catalytic performance in polyethylene low-temperature combustion.展开更多
Patent foramen ovale(PFO)is a remnant of normal fetal anatomy,which occurs in about 20%–25%of cases.Patients with PFO are at increased risk for migraine,acute limb ischemia secondary to emboli and cryptogenic(no othe...Patent foramen ovale(PFO)is a remnant of normal fetal anatomy,which occurs in about 20%–25%of cases.Patients with PFO are at increased risk for migraine,acute limb ischemia secondary to emboli and cryptogenic(no other identifiable cause)stroke.The traditional approach has been to use a fluoroscopically guided blocking device,but this is contraindicated in patients with severe allergies to contrast media or inability to undergo angiography.With the advancements in technology,ultrasonic robotic systems have become available for medical procedures.In the current study,we reported a case of using the ultrasonic robotic teleoperation system to achieve closure of PFO at the Chinese PLA General Hospital,Beijing,China.展开更多
Large animal models of cardiac ischemia-reperfusion are critical for evaluation of the efficacy of cardioprotective interventions prior to clinical translation.Nonetheless,current cardioprotective strategies/intervent...Large animal models of cardiac ischemia-reperfusion are critical for evaluation of the efficacy of cardioprotective interventions prior to clinical translation.Nonetheless,current cardioprotective strategies/interventions formulated in preclinical cardiovascular research are often limited to small animal models,which are not transferable or reproducible in large animal models due to different factors such as:(i)complex and varied features of human ischemic cardiac disease(ICD),which are challenging to mimic in animal models,(ii)significant differences in surgical techniques applied,and(iii)differences in cardiovascular anatomy and physiology between small versus large animals.This article highlights the advantages and disadvantages of different large animal models of preclinical cardiac ischemic reperfusion injury(IRI),as well as the different methods used to induce and assess IRI,and the obstacles faced in using large animals for translational research in the settings of cardiac IR.展开更多
A Synchronous Photometry Data Extraction(SPDE)program,performing indiscriminate monitoring of all stars appearing in the same field of view of an astronomical image,is developed by integrating several Astropy affiliat...A Synchronous Photometry Data Extraction(SPDE)program,performing indiscriminate monitoring of all stars appearing in the same field of view of an astronomical image,is developed by integrating several Astropy affiliated packages to make full use of time series observed by traditional small/medium aperture ground-based telescopes.The complete full-frame stellar photometry data reductions implemented for the two time series of cataclysmic variables:RX J2102.0+3359 and Paloma J0524+4244 produce 363 and 641 optimal light curves,respectively.A cross-identification with SIMBAD finds 23 known stars,of which 16 are red giant-/horizontal-branch stars,2 W UMa-type eclipsing variables,2 program stars,an X-ray source and 2 Asteroid Terrestrial-impact Last Alert System variables.Based on the data products from the SPDE program,a follow-up light curve analysis program identifies 32 potential variable light curves,of which 18 are from the time series of RX J2102.0+3359,and 14 are from that of Paloma J0524+4244.They are preliminarily separated into periodic,transient,and peculiar types.By querying for the 58 VizieR online data catalogs,their physical parameters and multi-band brightness spanning X-ray to radio are compiled for future analysis.展开更多
The experiments were conducted to focus on the desulfurization and evaporation characteristics of lime slurry droplets at 298-383 K. We designed an evaporation-reaction chamber with quartz glass windows.The monodisper...The experiments were conducted to focus on the desulfurization and evaporation characteristics of lime slurry droplets at 298-383 K. We designed an evaporation-reaction chamber with quartz glass windows.The monodisperse slurry droplet stream was injected into the evaporation reaction chamber, and the inlet gas components(air, air + SO_(2)) were introduced into the chamber. We applied the magnified digital in-line holography to measure the droplet parameters and calculated the evaporation rate. The effects of temperature, droplet concentration, and SO_(2) concentration on the evaporation rate of Ca(OH)_(2) droplets were discussed. Moreover, the Ca(OH)_(2) droplets under different experimental conditions were sampled,and the droplets were observed and analyzed using an off-line microscope. The evaporation rate of the Ca(OH)_(2) droplet increased at first, and then decreased during the falling process, and remained constant at last. The average evaporation rate of the Ca(OH)_(2) droplets increased significantly with the temperature increasing.展开更多
This work dealt with the damping performance and its underlying mechanism in SiC nanoparticles reinforced AZ91D composite(SiC_(np)/AZ91D)processed by cyclic extrusion and compression(CEC).It was found that the CEC pro...This work dealt with the damping performance and its underlying mechanism in SiC nanoparticles reinforced AZ91D composite(SiC_(np)/AZ91D)processed by cyclic extrusion and compression(CEC).It was found that the CEC process significantly affects the damping performance of the composite due to alterations in the density of dislocations and grain boundaries in the matrix alloy.Although there would be dynamic precipitation of the Mg17Al12 phase during processing which increases the phase interface and limits the mobility of dislocations and grain boundaries.The results also showed that the damping capacity of 1%SiC_(np)/AZ91D composite continuously decreases with adding CEC pass number and it consistently increases with rising the applied temperature.Considering the first derivative of the tanδ-T curve,the dominant damping mechanism based on test temperature can be divided into three regions.These three regions are as follows(i)dislocation vibration of the weak pinning points(≤T_(cr)),(ii)dislocation vibration of the strong pinning points(T_(cr)∼T_(V)),and(iii)grain boundary/interface sliding(≥T_(V))展开更多
Due to the insufficient slip systems in hexagonal close-packed structure,twinning is frequently activated to support stable plastic deformation of Mg alloy.In this work,we found four typical twin-like interfaces with ...Due to the insufficient slip systems in hexagonal close-packed structure,twinning is frequently activated to support stable plastic deformation of Mg alloy.In this work,we found four typical twin-like interfaces with misorientations of 102°,109°,142°and 149°,respectively,which had not only a shared[1120]zone axis of neighboring grains,but also overlapped diffraction spots similar to twins.However,highresolution transmission electron microscope(HRTEM)analysis revealed that the interfaces in real space deviated from the supposed twinning planes in reciprocal space,i.e.their overlapped diffraction spots.We clarified that the incoherent interfaces were co-axial grain boundaries(CGBs).Additionally,a special angle ofθ,close to 90°,between the interface and one side of basal plane,was frequently formed in CGBs.We proposed that interaction of multiple twinning contributes to the formation of CGBs,and theθis formed due to alternative tensile and compression twinning under a uniaxial loading.展开更多
Three A10 absolute gravimeters(AGs) were first acquired in China by the Hubei Earthquake Agency under the Belt and Road Seismic Monitoring Network Project. Although AG measuring and testing technique is not new, the p...Three A10 absolute gravimeters(AGs) were first acquired in China by the Hubei Earthquake Agency under the Belt and Road Seismic Monitoring Network Project. Although AG measuring and testing technique is not new, the purchase and simultaneous testing of 3 A10 absolute gravimeters is unprecedented in China. This study conducted the first acceptance testing of the AGs at 3 locations(the Jiufengshan Gravity Observation Station, the Global Navigation Satellite System Observation Station in Wuhan, and the Jiugongshan Observation Station in Xianning). The results were compared using a method based on expert validation, and the acceptance testing scheme was formulated by referring to the Technical Regulations for Tectonic Environment Monitoring Networks in China and Specifications for Gravimetry Control. Based on the repeatability, precision, and consistency of the measured g values, the results from each instrument were evaluated using the air pressure precision test. Comparing the instrument reference values, the final test results can identify the indicator parameters for 3 A10 AGs, the effects of the surrounding environment, and the related parameters on measurement precision. The precision of A10-059, A10-058, and A10-057 exceeded 0.78 μGal, 0.79 μGal, and 0.42 μGal, respectively.This testing scheme can be used as a reference for conducting acceptance testing of AGs in the future and obtaining absolute gravimetric measurements.展开更多
BACKGROUND Gastrointestinal stromal tumors(GISTs)are rare tumors of the gastrointestinal tract accounting for less than 1%of all gut tumors.GISTs occurring in the rectum are extremely rare,and these usually present at...BACKGROUND Gastrointestinal stromal tumors(GISTs)are rare tumors of the gastrointestinal tract accounting for less than 1%of all gut tumors.GISTs occurring in the rectum are extremely rare,and these usually present at an advanced stage compared with other sites.CASE SUMMARY A 60-year-old male who presented with features of sensations of rectal tenesmus was referred to our department with a mass in the lower rectum that was detected during a routine checkup.Colonoscopy,transrectal ultrasound,perianal magnetic resonance imaging and ultrasonic contrast were used to diagnose the rectum GIST,and then the patient underwent complete transanal resection using the ultrasonic scalpel.The patient was discharged ten days after the operation and was defined as low risk.Therefore,he had no need to receive subsequent adjuvant therapies,and he had not suffered any anal dysfunction or had any evidence of recurrence at follow up.CONCLUSION Surgical resection with histologically negative margins is the standard curative treatment for rectal GISTs.Appropriate surgical techniques based on the location,size,and resectability of the tumor should attract great attention from clinicians.展开更多
Lignin is the most abundant aromatic compound found in nature.The rich functional groups of lignin are responsible for its antibacterial,antioxidant,anti-ultraviolet,and biocompatible properties.As modified lignin has...Lignin is the most abundant aromatic compound found in nature.The rich functional groups of lignin are responsible for its antibacterial,antioxidant,anti-ultraviolet,and biocompatible properties.As modified lignin has a higher molecular weight,water solubility,and better surface activity,it is a good candidate for the construction of new biological materials.Ligninbased hydrogels are a type of functional materials with broad application prospects in the biomedical field.This review aimed to introduce the biological properties of lignin and the application of lignin-based hydrogels in the biological field.展开更多
基金jointly supported by the National Key Research and Development Program of China(Grant No.2022YFE0106500)Jiangsu Science Fund for Distinguished Young Scholars(Grant No.BK20200040)。
文摘The pan-Arctic is confronted with air pollution transported from lower latitudes.Observations have shown that aerosols help increase plant photosynthesis through the diffuse radiation fertilization effects(DRFEs).While such DRFEs have been explored at low to middle latitudes,the aerosol impacts on pan-Arctic ecosystems and the contributions by anthropogenic and natural emission sources remain less quantified.Here,we perform regional simulations at 0.2o×0.2ousing a well-validated vegetation model(Yale Interactive terrestrial Biosphere,YIBs)in combination with multi-source of observations to quantify the impacts of aerosol DRFEs on the net primary productivity(NPP)in the pan-Arctic during 2001-19.Results show that aerosol DRFEs increase pan-Arctic NPP by 2.19 Pg C(12.8%)yr^(-1)under clear-sky conditions,in which natural and anthropogenic sources contribute to 8.9% and 3.9%,respectively.Under all-sky conditions,such DRFEs are largely dampened by cloud to only 0.26 Pg C(1.24%)yr^(-1),with contributions of 0.65% by natural and 0.59% by anthropogenic species.Natural aerosols cause a positive NPP trend of 0.022% yr^(-1)following the increased fire activities in the pan-Arctic.In contrast,anthropogenic aerosols induce a negative trend of-0.01% yr^(-1)due to reduced emissions from the middle latitudes.Such trends in aerosol DRFEs show a turning point in the year of 2007 with more positive NPP trends by natural aerosols but negative NPP trends by anthropogenic aerosols thereafter.Though affected by modeling uncertainties,this study suggests a likely increasing impact of aerosols on terrestrial ecosystems in the pan-Arctic under global warming.
基金the financial support from the National Natural Science Foundation of China(21908010)Jilin Provincial Department of Science and Technology(20220101089JC)the Education Department of Jilin Province(JJKH20220694KJ)。
文摘High-temperature treatment is key to the preparation of zeolite catalysts.Herein,the effects of hightemperature treatment on the property and performance of HZSM-5 zeolites were studied in this work.X-Ray diffraction,N2physisorption,27Al magic angle spinning nuclear magnetic resonance(MAS NMR),and temperature-programmed desorption of ammonia results indicated that the hightemperature treatment at 650℃ hardly affected the inherent crystal and texture of HZSM-5zeolites but facilitated the conversion of framework Al to extra-framework Al,reducing the acid site and enhancing the acid strength.Moreover,the high-temperature treatment improved the performance of HZSM-5 zeolites in n-heptane catalytic cracking,promoting the conversion and light olefins yield while inhibiting coke formation.Based on the kinetic and mechanism analysis,the improvement of HZSM-5 performance caused by high-temperature treatment has been attributed to the formation of extra-framework Al,which enhanced the acid strength,facilitated the bimolecular reaction,and promoted the entropy change to overcome a higher energy barrier in n-heptane catalytic cracking.
基金The authors are grateful for the support by National Key Research and Development Program of China(2021YFF0500300,2020YFB1708300)the National Natural Science Foundation of China(52205280,12172041).
文摘Lightweight thin-walled structures with lattice infill are widely desired in satellite for their high stiffness-to-weight ratio and superior buckling strength resulting fromthe sandwich effect.Such structures can be fabricated bymetallic additive manufacturing technique,such as selective laser melting(SLM).However,the maximum dimensions of actual structures are usually in a sub-meter scale,which results in restrictions on their appliance in aerospace and other fields.In this work,a meter-scale thin-walled structure with lattice infill is designed for the fuel tank supporting component of the satellite by integrating a self-supporting lattice into the thickness optimization of the thin-wall.The designed structure is fabricated by SLM of AlSi10Mg and cold metal transfer welding technique.Quasi-static mechanical tests and vibration tests are both conducted to verify the mechanical strength of the designed large-scale lattice thin-walled structure.The experimental results indicate that themeter-scale thin-walled structure with lattice infill could meet the dimension and lightweight requirements of most spacecrafts.
基金supported by the National Natural Science Foundation of China(Nos.52171125,52071178)The fundamental Research Funds for the Central Universities,China(No.2682020ZT114)+1 种基金the Key R&D Projects in the Field of High and New Technology of Sichuan Province,China(Nos.20ZDYF0490,20ZDYF0236)Open Funding of International Joint Laboratory for Light Alloys(MOE),Chongqing University,China。
基金supported by the National Natural Science Foundation of China(Nos.52171125,52071178)the Open Testing Funding of Large Instruments and Equipment of Southwest Jiaotong University,China(No.2022SRII-003)the Open Funding of International Joint Laboratory for Light Alloys(MOE),Chongqing University,China。
基金the National Natural Science Foundation of China(NSFC)under Grant Nos.#61905087,and#61935008Tsinghua University(School of Materials Science and Engineering)-AVIC Aerodynamics Research Institute Joint Research Center for Advanced Materials and AntiIcing Nos.#JCAMAI-2020-03+2 种基金Fundamental Research Funds for the Central Universities Nos.#2020-JCXK-18Jilin Province Development and Reform Commission Project Nos.#2022C047-4Key Laboratory of Icing and Anti/De-icing of CARDC Nos.#IADL 20210404。
文摘Carnivorous plants,for instance,Dionaea muscipula and Nepenthes pitcher plant,inspired the innovation of advanced stimuli-responsive actuators and lubricant-infused slippery surfaces,respectively.However,hybrid bionic devices that combine the active and passive prey trapping capabilities of the two kinds of carnivorous plants remain a challenge.Herein,we report a moisture responsive shape-morphing slippery surface that enables both moisture responsive shapemorphing and oil-lubricated water repellency for simultaneous active-and passive-droplet manipulation.The moisture deformable slippery surface is prepared by creating biomimetic microstructures on graphene oxide(GO)membrane via femtosecond laser direct writing and subsequent lubricating with a thin layer of oil on the laser structured reduced GO(LRGO)surface.The integration of a lubricant-infused slippery surface with an LRGO/GO bilayer actuator endows the actuator with droplet sliding ability and promotes the moisture deformation performance due to oil-enhanced water repellency of the inert layer(LRGO).Based on the shape-morphing slippery surface,we prepared a series of proof-of-concept actuators,including a moisture-response Dionaea muscipula actuator,a smart frog tongue,and a smart flower,demonstrating their versatility for active/passive trapping,droplet manipulation,and sensing.
基金the financial support from the National Natural Science Foundation of China(21908010)Jilin Provincial Department of Science and Technology(20220101089JC)the Education Department of Jilin Province(JJKH20220694KJ)。
文摘Globally,the efficient utilization of polymer wastes is one of the most important issues for current sustainable development topics.Herein,a green and efficient low-temperature combustion approach is proposed to deal with polymer wastes and recover heat energy,simultaneously alleviating the environment and energy crisis.Non-noble metal oxides(Al_(2)O_(3),Fe_(2)O_(3),NiO_(2),ZrO_(2),La_(2)O_(3)and CeO_(2)) were prepared,characterized and screened to boost the low-temperature combustion of polyethylene waste at 300℃ in air.The mass change,heat release and CO_(x) formation were studied in details and employed to evaluate the combustion rate and efficiency.It was found that CeO_(2)significantly enhanced the combustion rate and efficiency,which was respectively 2 and 7 times that of non-catalytic case.An interesting phenomenon was observed that the catalytic performance of CeO_(2) in polyethylene low-temperature combustion was significantly improved by the 7-day storage in the room environment or water treatment.XPS analysis confirmed the co-existence of Ce^(3+) and Ce^(4+) in CeO_(2),and the 7-day storage and water treatment promoted the amount of Ce^(3+),which facilitated the formation of the oxygen vacancies.That may be the reason why CeO_(2) exhibited excellent catalytic performance in polyethylene low-temperature combustion.
基金the National Key Research and Development Program(2021YFC2501106)the Key Discipline Construction Project of Chinese PLA Medical College during the 13^(th) Five-Year Plan Period(A350109).
文摘Patent foramen ovale(PFO)is a remnant of normal fetal anatomy,which occurs in about 20%–25%of cases.Patients with PFO are at increased risk for migraine,acute limb ischemia secondary to emboli and cryptogenic(no other identifiable cause)stroke.The traditional approach has been to use a fluoroscopically guided blocking device,but this is contraindicated in patients with severe allergies to contrast media or inability to undergo angiography.With the advancements in technology,ultrasonic robotic systems have become available for medical procedures.In the current study,we reported a case of using the ultrasonic robotic teleoperation system to achieve closure of PFO at the Chinese PLA General Hospital,Beijing,China.
基金supported by the Early Career Scheme(ECS)2022/23(CUHK 24110822)from the Research Grants Council of Hong Kongthe Direct Grant for Research 2020/21(2020.035)+3 种基金Project Impact Enhancement Fund(PIEF)(PIEF/Ph2/COVID/08)Improvement on Competitiveness in Hiring New Faculties Funding Scheme from CUHK as well as the Centre for Cardiovascular Genomics and Medicine(CCGM)of the Lui Che Woo Institute of Innovative Medicine CUHK(to S.B.O.)a CUHK Department of Medicine&Therapeutics(MEDT)-funded PhD studenta CUHK Vice-Chancellor’s PhD Scholarship holder。
文摘Large animal models of cardiac ischemia-reperfusion are critical for evaluation of the efficacy of cardioprotective interventions prior to clinical translation.Nonetheless,current cardioprotective strategies/interventions formulated in preclinical cardiovascular research are often limited to small animal models,which are not transferable or reproducible in large animal models due to different factors such as:(i)complex and varied features of human ischemic cardiac disease(ICD),which are challenging to mimic in animal models,(ii)significant differences in surgical techniques applied,and(iii)differences in cardiovascular anatomy and physiology between small versus large animals.This article highlights the advantages and disadvantages of different large animal models of preclinical cardiac ischemic reperfusion injury(IRI),as well as the different methods used to induce and assess IRI,and the obstacles faced in using large animals for translational research in the settings of cardiac IR.
基金partly supported by the CAS Light of West China Programthe Yunnan Youth Talent Project+3 种基金the Yunnan Fundamental Research Projects(grant No.2016FB007,No.202201AT070180)the National Natural Science Foundation of China(NSFC,No.11933008)partially supported by the Open Project Program of the CAS Key Laboratory of Optical Astronomy,National Astronomical Observatories,Chinese Academy of Sciencessupport from the Yunnan Fundamental Research Key Projects(grant No.202001BB050032)。
文摘A Synchronous Photometry Data Extraction(SPDE)program,performing indiscriminate monitoring of all stars appearing in the same field of view of an astronomical image,is developed by integrating several Astropy affiliated packages to make full use of time series observed by traditional small/medium aperture ground-based telescopes.The complete full-frame stellar photometry data reductions implemented for the two time series of cataclysmic variables:RX J2102.0+3359 and Paloma J0524+4244 produce 363 and 641 optimal light curves,respectively.A cross-identification with SIMBAD finds 23 known stars,of which 16 are red giant-/horizontal-branch stars,2 W UMa-type eclipsing variables,2 program stars,an X-ray source and 2 Asteroid Terrestrial-impact Last Alert System variables.Based on the data products from the SPDE program,a follow-up light curve analysis program identifies 32 potential variable light curves,of which 18 are from the time series of RX J2102.0+3359,and 14 are from that of Paloma J0524+4244.They are preliminarily separated into periodic,transient,and peculiar types.By querying for the 58 VizieR online data catalogs,their physical parameters and multi-band brightness spanning X-ray to radio are compiled for future analysis.
基金supported by the National Natural Science Fund for Distinguished Young Scholars (No. 51825605)。
文摘The experiments were conducted to focus on the desulfurization and evaporation characteristics of lime slurry droplets at 298-383 K. We designed an evaporation-reaction chamber with quartz glass windows.The monodisperse slurry droplet stream was injected into the evaporation reaction chamber, and the inlet gas components(air, air + SO_(2)) were introduced into the chamber. We applied the magnified digital in-line holography to measure the droplet parameters and calculated the evaporation rate. The effects of temperature, droplet concentration, and SO_(2) concentration on the evaporation rate of Ca(OH)_(2) droplets were discussed. Moreover, the Ca(OH)_(2) droplets under different experimental conditions were sampled,and the droplets were observed and analyzed using an off-line microscope. The evaporation rate of the Ca(OH)_(2) droplet increased at first, and then decreased during the falling process, and remained constant at last. The average evaporation rate of the Ca(OH)_(2) droplets increased significantly with the temperature increasing.
基金This work was supported by the National Natural Science Foundation of China(Grant Numbers of U1902220,51674166,51374145,51074106,50674067)the National Key Research and Development Program of China(Grant Number 2016YFB0301001).
文摘This work dealt with the damping performance and its underlying mechanism in SiC nanoparticles reinforced AZ91D composite(SiC_(np)/AZ91D)processed by cyclic extrusion and compression(CEC).It was found that the CEC process significantly affects the damping performance of the composite due to alterations in the density of dislocations and grain boundaries in the matrix alloy.Although there would be dynamic precipitation of the Mg17Al12 phase during processing which increases the phase interface and limits the mobility of dislocations and grain boundaries.The results also showed that the damping capacity of 1%SiC_(np)/AZ91D composite continuously decreases with adding CEC pass number and it consistently increases with rising the applied temperature.Considering the first derivative of the tanδ-T curve,the dominant damping mechanism based on test temperature can be divided into three regions.These three regions are as follows(i)dislocation vibration of the weak pinning points(≤T_(cr)),(ii)dislocation vibration of the strong pinning points(T_(cr)∼T_(V)),and(iii)grain boundary/interface sliding(≥T_(V))
基金supported by the National Key R&D Program of China[grant number 2021YFA1200203]the Key Program of National Natural Science Foundation of China[grant number 51931003]+3 种基金the National Natural Science Foundation of China[grant numbers 52171118,52071178,51901103]the Projects in Science and Technique Plans of Ningbo City[grant number 2019B10083]the China Postdoctoral Science Foundation[grant number 2021M701715]the Opening Project of the Key Laboratory of Advanced Manufacturing and Intelligent Technology(Ministry of Education)of Harbin University of Science and Technology[grant number KFKT202103]
文摘Due to the insufficient slip systems in hexagonal close-packed structure,twinning is frequently activated to support stable plastic deformation of Mg alloy.In this work,we found four typical twin-like interfaces with misorientations of 102°,109°,142°and 149°,respectively,which had not only a shared[1120]zone axis of neighboring grains,but also overlapped diffraction spots similar to twins.However,highresolution transmission electron microscope(HRTEM)analysis revealed that the interfaces in real space deviated from the supposed twinning planes in reciprocal space,i.e.their overlapped diffraction spots.We clarified that the incoherent interfaces were co-axial grain boundaries(CGBs).Additionally,a special angle ofθ,close to 90°,between the interface and one side of basal plane,was frequently formed in CGBs.We proposed that interaction of multiple twinning contributes to the formation of CGBs,and theθis formed due to alternative tensile and compression twinning under a uniaxial loading.
基金supported by the Open Fund of Wuhan,Gravitation and Solid Earth Tides,National Observation and Research Station (No. WHYWZ202214)the Scientific Research Fund of Institute of Seismology and Institute of Crustal Dynamics,China Earthquake Administration (Grant No.IS202236336, No. IS202226326)+1 种基金the Researchof Hubei Earthquake Agency (No. 2022HBJJ039)the National Natural Science Foundation of China (No. 41774093)
文摘Three A10 absolute gravimeters(AGs) were first acquired in China by the Hubei Earthquake Agency under the Belt and Road Seismic Monitoring Network Project. Although AG measuring and testing technique is not new, the purchase and simultaneous testing of 3 A10 absolute gravimeters is unprecedented in China. This study conducted the first acceptance testing of the AGs at 3 locations(the Jiufengshan Gravity Observation Station, the Global Navigation Satellite System Observation Station in Wuhan, and the Jiugongshan Observation Station in Xianning). The results were compared using a method based on expert validation, and the acceptance testing scheme was formulated by referring to the Technical Regulations for Tectonic Environment Monitoring Networks in China and Specifications for Gravimetry Control. Based on the repeatability, precision, and consistency of the measured g values, the results from each instrument were evaluated using the air pressure precision test. Comparing the instrument reference values, the final test results can identify the indicator parameters for 3 A10 AGs, the effects of the surrounding environment, and the related parameters on measurement precision. The precision of A10-059, A10-058, and A10-057 exceeded 0.78 μGal, 0.79 μGal, and 0.42 μGal, respectively.This testing scheme can be used as a reference for conducting acceptance testing of AGs in the future and obtaining absolute gravimetric measurements.
基金Supported by National Nature Science Foundation of China,No.82004374the second round of construction project for the National Traditional Chinese Medicine Academic School Inheritance Studio+1 种基金the three-year action project for Shanghai to further accelerate the inheritance innovation and development of traditional Chinese medicine,No.ZY[2021-2023]-0209Shanghai"Rising Stars of Medical Talents"Youth Development Program,Youth Medical Talents–Specialist Program,No.[2021]-099.
文摘BACKGROUND Gastrointestinal stromal tumors(GISTs)are rare tumors of the gastrointestinal tract accounting for less than 1%of all gut tumors.GISTs occurring in the rectum are extremely rare,and these usually present at an advanced stage compared with other sites.CASE SUMMARY A 60-year-old male who presented with features of sensations of rectal tenesmus was referred to our department with a mass in the lower rectum that was detected during a routine checkup.Colonoscopy,transrectal ultrasound,perianal magnetic resonance imaging and ultrasonic contrast were used to diagnose the rectum GIST,and then the patient underwent complete transanal resection using the ultrasonic scalpel.The patient was discharged ten days after the operation and was defined as low risk.Therefore,he had no need to receive subsequent adjuvant therapies,and he had not suffered any anal dysfunction or had any evidence of recurrence at follow up.CONCLUSION Surgical resection with histologically negative margins is the standard curative treatment for rectal GISTs.Appropriate surgical techniques based on the location,size,and resectability of the tumor should attract great attention from clinicians.
基金the financial support from the National Natural Science Foundation of China(32171717)the Young Elite Scientists Sponsorship Program(YESS20200389).
文摘Lignin is the most abundant aromatic compound found in nature.The rich functional groups of lignin are responsible for its antibacterial,antioxidant,anti-ultraviolet,and biocompatible properties.As modified lignin has a higher molecular weight,water solubility,and better surface activity,it is a good candidate for the construction of new biological materials.Ligninbased hydrogels are a type of functional materials with broad application prospects in the biomedical field.This review aimed to introduce the biological properties of lignin and the application of lignin-based hydrogels in the biological field.
