We report the detection of a large sample of high-α-metal-rich stars on the low giant branch with 2.6<log g<3.3 dex in the LAMOST-MRS survey.This special group corresponds to an intermediate-age population of 5...We report the detection of a large sample of high-α-metal-rich stars on the low giant branch with 2.6<log g<3.3 dex in the LAMOST-MRS survey.This special group corresponds to an intermediate-age population of 5-9 Gyr based on the[Fe/H]-[C/N]diagram and age-[C/N]calibration.A comparison group is selected to have a solarαratio at super metallicity,which is young and has a narrow age range around 3 Gyr.Both groups have thin-disk like kinematics but the former shows slightly large velocity dispersions.The special group shows a larger extension in a vertical distance toward 1.2 kpc,a second peak at smaller Galactic radius and a larger fraction of super metal rich stars with[Fe/H]>0.2 than the comparison group.These properties strongly indicate its connection with the outer bar/bulge region at R=3-5 kpc.A tentative interpretation of this special group is that its stars were formed in the X-shaped bar/bulge region,close to its corotation radius,where radial migration is the most intense,and brings them to present locations at 9 kpc and beyond.Low eccentricities and slightly outward radial excursions of its stars are consistent with this scenario.Its kinematics(cold)and chemistry([α/Fe]~0.1)further support the formation of the instability-driven X-shaped bar/bulge from the thin disk.展开更多
Background:Awake craniotomy(AC)has become gold standard in surgical resection of gliomas located in eloquent areas.The conscious sedation techniques in AC include both monitored anesthesia care(MAC)and asleep-awake-as...Background:Awake craniotomy(AC)has become gold standard in surgical resection of gliomas located in eloquent areas.The conscious sedation techniques in AC include both monitored anesthesia care(MAC)and asleep-awake-asleep(AAA).The choice of optimal anesthetic method depends on the preferences of the surgical team(mainly anesthesiologist and neurosurgeon).The aim of this study was to compare the difference in physiological and blood gas data,dosage of different drugs,the probability of switching to endotracheal intubation,and extent of tumor resection and dysfunction after operation between AAA and MAC anesthetic management for resection of gliomas in eloquent brain areas.Methods:Two-hundred and twenty-five patients with super-tentorial tumor located in eloquent areas underwent AC from 2009 to 2021 in Xijing Hospital.Forty-one patients underwent AAA technique,and the rest one-hundred eighty-four patients underwent MAC technique.Anesthetic management,dosage of different drugs,intraoperative complications,postoperative outcomes,adverse events,extent of resection and motor,and sensory and language dysfunction after operation were compared between MAC and AAA.Result:There was no significant difference in gender,KPS score,MMSE score,glioma grade,type,and growth site between the patients in the two groups,except the older age of patients in MAC group than that in AAA group.During the whole process of operation,there were greater pulse pressure difference(P=0.046),shorter operation time(P=0.039),less dosage of remifentanil(P=0.000),more dosage of dexmedetomidine(P=0.013),more use of antiemetics(81%,P=0.0067),lower use of vasoactive agent(45.1%,P=0.010),and lower probability of conversion to general anesthesia(GA,P=0.027)in MAC group than that in AAA group.Blood gas analysis showed that PetCO2(P=0.000),Glu concentration(P=0.000),and PaCO2(P=0.000)were higher,but SPO2(P=0.002)and PaO2(P=0.000)were lower in MAC group than that in AAA group.In the postoperative recovery stage,compared with that of AAA group,the probability of dysfunction in MAC group at 1,3,5,and 7 days after operation was lower,which were 27.8%vs 53.6%(P=0.003),31%vs 68.3%(P=0.000),28.8%vs 63.4%(P=0.000),and 25.6%vs 58.5%(P=0.000),respectively.Conclusion:Compared with AAA,it seems that MAC has more advantages in the management for resection of gliomas in eloquent brain areas,and MAC combined with multiple monitoring such as cerebral cortical mapping,neuronavigation,and ultrasonic detection is worthy of popularization for the resection of gliomas in eloquent brain areas.展开更多
基金supported by the National Natural Science Foundation of China(Nos.11988101,11625313,11890694,11973048 and 11927804)the 2-m Chinese Space Survey Telescope project and the National Key R&D Program of China(No.2019YFA0405502)+2 种基金supported by the Astronomical Big Data Joint Research Center,co-founded by the National Astronomical Observatories,Chinese Academy of Sciences and the Alibaba CloudThe Guo Shou Jing Telescope(the Large Sky Area Multi-Object Fiber Spectroscopic Telescope LAMOST)is a National Major Scientific Project built by the Chinese Academy of Sciencesprovided by the National Development and Reform Commission。
文摘We report the detection of a large sample of high-α-metal-rich stars on the low giant branch with 2.6<log g<3.3 dex in the LAMOST-MRS survey.This special group corresponds to an intermediate-age population of 5-9 Gyr based on the[Fe/H]-[C/N]diagram and age-[C/N]calibration.A comparison group is selected to have a solarαratio at super metallicity,which is young and has a narrow age range around 3 Gyr.Both groups have thin-disk like kinematics but the former shows slightly large velocity dispersions.The special group shows a larger extension in a vertical distance toward 1.2 kpc,a second peak at smaller Galactic radius and a larger fraction of super metal rich stars with[Fe/H]>0.2 than the comparison group.These properties strongly indicate its connection with the outer bar/bulge region at R=3-5 kpc.A tentative interpretation of this special group is that its stars were formed in the X-shaped bar/bulge region,close to its corotation radius,where radial migration is the most intense,and brings them to present locations at 9 kpc and beyond.Low eccentricities and slightly outward radial excursions of its stars are consistent with this scenario.Its kinematics(cold)and chemistry([α/Fe]~0.1)further support the formation of the instability-driven X-shaped bar/bulge from the thin disk.
基金funded by multidisciplinary MDT diagnosis and treatment fund for glioma and academic discipline boosting of Xijing Hospital.
文摘Background:Awake craniotomy(AC)has become gold standard in surgical resection of gliomas located in eloquent areas.The conscious sedation techniques in AC include both monitored anesthesia care(MAC)and asleep-awake-asleep(AAA).The choice of optimal anesthetic method depends on the preferences of the surgical team(mainly anesthesiologist and neurosurgeon).The aim of this study was to compare the difference in physiological and blood gas data,dosage of different drugs,the probability of switching to endotracheal intubation,and extent of tumor resection and dysfunction after operation between AAA and MAC anesthetic management for resection of gliomas in eloquent brain areas.Methods:Two-hundred and twenty-five patients with super-tentorial tumor located in eloquent areas underwent AC from 2009 to 2021 in Xijing Hospital.Forty-one patients underwent AAA technique,and the rest one-hundred eighty-four patients underwent MAC technique.Anesthetic management,dosage of different drugs,intraoperative complications,postoperative outcomes,adverse events,extent of resection and motor,and sensory and language dysfunction after operation were compared between MAC and AAA.Result:There was no significant difference in gender,KPS score,MMSE score,glioma grade,type,and growth site between the patients in the two groups,except the older age of patients in MAC group than that in AAA group.During the whole process of operation,there were greater pulse pressure difference(P=0.046),shorter operation time(P=0.039),less dosage of remifentanil(P=0.000),more dosage of dexmedetomidine(P=0.013),more use of antiemetics(81%,P=0.0067),lower use of vasoactive agent(45.1%,P=0.010),and lower probability of conversion to general anesthesia(GA,P=0.027)in MAC group than that in AAA group.Blood gas analysis showed that PetCO2(P=0.000),Glu concentration(P=0.000),and PaCO2(P=0.000)were higher,but SPO2(P=0.002)and PaO2(P=0.000)were lower in MAC group than that in AAA group.In the postoperative recovery stage,compared with that of AAA group,the probability of dysfunction in MAC group at 1,3,5,and 7 days after operation was lower,which were 27.8%vs 53.6%(P=0.003),31%vs 68.3%(P=0.000),28.8%vs 63.4%(P=0.000),and 25.6%vs 58.5%(P=0.000),respectively.Conclusion:Compared with AAA,it seems that MAC has more advantages in the management for resection of gliomas in eloquent brain areas,and MAC combined with multiple monitoring such as cerebral cortical mapping,neuronavigation,and ultrasonic detection is worthy of popularization for the resection of gliomas in eloquent brain areas.
