Odor pollution in landfill area has attracted more social attention in China. It is very important to control the generation of odor pollutants in situ. Analyzing odorous materials production form buried waste, simula...Odor pollution in landfill area has attracted more social attention in China. It is very important to control the generation of odor pollutants in situ. Analyzing odorous materials production form buried waste, simulated columns of different volatile solid (VS) content and different buried period waste were designed. Gas compounds produced from the columns were collected and analyzed by comprehensive two-dimensional gas chromatography (GC × GC) method. It has remarkable relationship between VS content and concentrations of odorous material. When VS content more than 40%, the total amount of odorous compounds increases remarkably. It can be inferred that reduced VS content of original waste may effective decreasing odorous materials production in landfill area. The old rubbish produced more odorous compounds than that of fresh one in simulated columns.展开更多
Through a series of exploration based on PSR framework model,for the purpose of building a suitable Chongqing agricultural nonpoint source pollution evaluation index system model framework,combined with the presence o...Through a series of exploration based on PSR framework model,for the purpose of building a suitable Chongqing agricultural nonpoint source pollution evaluation index system model framework,combined with the presence of Chongqing specific agro-environmental issues,we build a agricultural non-point source pollution assessment index system,and then study the agricultural system pressure,agro-environmental status and human response in total 3 major categories,develope an agricultural non-point source pollution evaluation index consisting of 3 criteria indicators and 19 indicators. As can be seen from the analysis,pressures and responses tend to increase and decrease linearly,state and complex have large fluctuations,and their fluctuations are similar mainly due to the elimination of pressures and impact,increasing the impact for agricultural non-point source pollution.展开更多
Given the rapid changes in social structure(urbanization),economic structure(industrialization),and demographic structure(population aging)in China,cancer has become a major public health problem1.Extensive evidence h...Given the rapid changes in social structure(urbanization),economic structure(industrialization),and demographic structure(population aging)in China,cancer has become a major public health problem1.Extensive evidence has indicated that screening can decrease cancer mortality,particularly among high-risk groups,and several representative national and regional cancer screening programs have been launched in China to cope with the increasing burden of cancer.展开更多
AIM:To evaluate the predictive value of neutrophil infiltration as a marker of Helicobacter pylori(H.pylori) infection.METHODS:A total of 315 patients with dyspepsia symptoms who underwent upper gastrointestinal endos...AIM:To evaluate the predictive value of neutrophil infiltration as a marker of Helicobacter pylori(H.pylori) infection.METHODS:A total of 315 patients with dyspepsia symptoms who underwent upper gastrointestinal endoscopy were enrolled in this study.Biopsies were evaluated using the updated Sydney system.The medication history of all patients in the preceding 4 wk was recorded.The diagnosis of H.pylori infection was based on 13 C-urea breath test at least 4 wk after withdrawal of antisecretory drugs,antibiotics and related drugs.For the patients with subtotal gastrectomy,the diagnosis of H.pylori infection was based on anti-H.pylori immunoglobulin G(IgG) antibody.Serum anti-H.pylori IgG antibody was measured by enzyme-linked immunosorbent assays(Biohit,Finland).RESULTS:The sensitivity,specificity,positive predictive value and negative predictive value of neutrophil infiltration in the diagnosis of H.pylori infection were 92.3%,83.5%,77.4% and 94.7%,respectively.Neutrophil infiltration of gastric mucosa in the histological analysis was strongly associated with H.pylori infection(77.4% vs 5.3% in the neutrophil infiltration negative group,P = 0.000).Moderate neutrophil infiltration was more frequent in H.pylori infection when compared to mild infiltration(81.8% and 75%,respectively),but did not reach statistical significance.For those patients with negative rapid urease test,H.pylori was detected in 73.2% of patients with positive neutrophil infiltration on histology.In patients with subtotal gastrectomy,the diagnostic accuracy of neutrophil infiltration inH.pylori infection was 50%.CONCLUSION:Neutrophil infiltration is closely associated with H.pylori and may be recognized as a sign of this infection.展开更多
The prolonged mei-yu/baiu system with anomalous precipitation in the year 2020 has swollen many rivers and lakes,caused flash flooding,urban flooding and landslides,and consistently wreaked havoc across large swathes ...The prolonged mei-yu/baiu system with anomalous precipitation in the year 2020 has swollen many rivers and lakes,caused flash flooding,urban flooding and landslides,and consistently wreaked havoc across large swathes of China,particularly in the Yangtze River basin.Significant precipitation and flooding anomalies have already been seen in magnitude and extension so far this year,which have been exerting much higher pressure on emergency responses in flood control and mitigation than in other years,even though a rainy season with multiple ongoing serious flood events in different provinces is not that uncommon in China.Instead of delving into the causes of the uniqueness of this year’s extreme precipitation-flooding situation,which certainly warrants in-depth exploration,in this article we provide a short view toward a more general hydrometeorological solution to this annual nationwide problem.A“glocal”(global to local)hydrometeorological solution for floods(GHS-F)is considered to be critical for better preparedness,mitigation,and management of different types of significant precipitation-caused flooding,which happen extensively almost every year in many countries such as China,India and the United States.Such a GHS-F model is necessary from both scientific and operational perspectives,with the strength in providing spatially consistent flood definitions and spatially distributed flood risk classification considering the heterogeneity in vulnerability and resilience across the entire domain.Priorities in the development of such a GHS-F are suggested,emphasizing the user’s requirements and needs according to practical experiences with various flood response agencies.展开更多
Glucocorticoids(GCs)have been the mainstay of immunosuppressive therapy in solid organ transplantation(SOT)for decades,due to their potent effects on innate immunity and tissue protective effects.However,some SOT cent...Glucocorticoids(GCs)have been the mainstay of immunosuppressive therapy in solid organ transplantation(SOT)for decades,due to their potent effects on innate immunity and tissue protective effects.However,some SOT centers are reluctant to administer GCs long-term because of the various related side effects.This review summarizes the advantages and disadvantages of GCs in SOT.PubMed and Scopus databases were searched from 2011 to April 2021 using search syntaxes covering“transplantation”and“glucocorticoids”.GCs are used in transplant recipients,transplant donors,and organ perfusate solution to improve transplant outcomes.In SOT recipients,GCs are administered as induction and maintenance immunosuppressive therapy.GCs are also the cornerstone to treat acute antibody-and T-cell-mediated rejections.Addition of GCs to organ perfusate solution and pretreatment of transplant donors with GCs are recommended by some guidelines and protocols,to reduce ischemia-reperfusion injury peri-transplant.GCs with low bioavailability and high potency for GC receptors,such as budesonide,nanoparticle-mediated targeted delivery of GCs to specific organs,and combination use of dexamethasone with inducers of immuneregulatory cells,are new methods of GC application in SOT patients to reduce side effects or induce immune-tolerance instead of immunosuppression.Various side effects involving different non-targeted organs/tissues,such as bone,cardiovascular,neuromuscular,skin and gastrointestinal tract,have been noted for GCs.There are also potential drug-drug interactions for GCs in SOT patients.展开更多
Agriculture is the foundation of national economy,and agricultural development is related to the rapid development of long-term stability of the society and economy. Agriculture includes farming,forestry,animal husban...Agriculture is the foundation of national economy,and agricultural development is related to the rapid development of long-term stability of the society and economy. Agriculture includes farming,forestry,animal husbandry,and fisheries. Agricultural listed company as an agricultural enterprise " leader",which directly affects the development of the entire growth of the agricultural industry development and policy,so the study of agricultural listed company's growth is particularly important. This paper uses AHP weighting method to evaluate 2012 financial data on the growth of agricultural listed companies.展开更多
Structural variants(SVs)are a type of genetic variation that contribute substantially to phenotypic diversity and evolution.Further study of SVs will help us understand the influence of SVs associated with tea quality...Structural variants(SVs)are a type of genetic variation that contribute substantially to phenotypic diversity and evolution.Further study of SVs will help us understand the influence of SVs associated with tea quality and stress resistance and provide new insight into tea plant breeding improvement and genetic research.However,SVs have not been thoroughly discovered in the tea plant genomes.Herein,we constructed a large-scale SV map across a population of 107 resequenced genomes,including both ancient and cultivated tea plants.A total of 44,240 highconfident SVs were identified,including 34,124 DEL(deletions),4,448 DUP(duplications),2,503 INV(inversions),544 INS(insertions)and 2,621 TRA(translocations).In total,12,400 protein-coding genes were overlapped with SVs,of which 49.5%were expressed in all five tea tissues.SVbased analysis of phylogenetic relationships and population structure in tea plants showed a consistent evolutionary history with the SNP-based results.We also identified SVs subject to artificial selection and found that genes under domestication were enriched in metabolic pathways involving theanine and purine alkaloids,biosynthesis of monoterpenoid,phenylpropanoid,fatty acid,and isoflavonoid,contributing to traits of agronomic interest in tea plants.In addition,a total of 27 terpene synthase(TPS)family genes were selected during domestication.These results indicate that these SVs could provide extensive genomic information for tea quality improvement.展开更多
Individual hydrocarbons identified to be macrocyclic alkanes in a torbanite from the Sydney Basin(Australia)were successfully isolated from its extracts using preparative gas chromatography and analyzed by NMR.Saturat...Individual hydrocarbons identified to be macrocyclic alkanes in a torbanite from the Sydney Basin(Australia)were successfully isolated from its extracts using preparative gas chromatography and analyzed by NMR.Saturated cyclic structures were confirmed by single peaks in the NMR~1H and~(13)C spectra indicating single forms of H and C atoms exist in these biomarker molecules.This is consistent with the methylene unit in a ring system assignment of the macrocyclic alkanes and accounts for a formula of(CH2)n.The unusual molecular structures of these compounds are consistent with those that were identified from previous GC retention index data and co-injection with a standard supports the previous research.The mass spectral fragmentation behaviors of representative cyclic alkanes were further investigated by comparing them with the mass spectra of isolated individual macrocyclic alkanes.The characteristic fragment ions in the macrocyclic alkanes of(M–28)+and base peaks of m/z 97,111,125,etc.,can be assigned as being generated by simple a-/i-cleavage and hydrogen rearrangement.These fragmentation pathways combined with retention indices should assist in differentiating these compounds from monounsaturated alkenes and alkylated monocyclics having similar mass spectral characteristics in other geological samples.展开更多
AIM:To investigate the effect of morroniside(Mor)on lipopolysaccharide(LPS)-treated iris pigment epithelial cells(IPE).METHODS:IPE cells were induced by LPS and treated with Mor.Cell proliferation was detected by cell...AIM:To investigate the effect of morroniside(Mor)on lipopolysaccharide(LPS)-treated iris pigment epithelial cells(IPE).METHODS:IPE cells were induced by LPS and treated with Mor.Cell proliferation was detected by cell counting kit(CCK)-8,apoptosis was detected by flow cytometry,the levels of tumor necrosis factor-α(TNF-α),interleukin(IL)-6,and IL-8 were measured by enzyme-linked immunosorbent assay(ELISA)kits,and the protein expression of TLR4,JAK2,p-JAK2,STAT3,and p-STAT3 was analyzed by Western blotting.In addition,overexpression of TLR4 and Mor treatment of LPS-stimulated IPE cells were also tested for the above indices.RESULTS:Mor effectively promoted the proliferation and inhibited the apoptosis of LPS-treated IPE cells.In addition,Mor significantly reduced the levels of TNF-α,IL-6,and IL-8 and significantly inhibited the expression of TLR4,p-JAK2,and p-STAT3 in LPS-treated IPE cells.The effect of Mor on LPS-treated IPE cells was markedly attenuated after overexpression of TLR4.CONCLUSION:These findings suggest that Mor may ameliorate LPS-induced inflammatory damage and apoptosis in IPE through inhibition of TLR4/JAK2/STAT3 pathway.展开更多
In recent years,more and more attention has been paid to normal childbirth.The World Health Organization(WHO),International Confederation of Midwives(ICM),Chinese Maternal and Child Health Association(CMCHA)have activ...In recent years,more and more attention has been paid to normal childbirth.The World Health Organization(WHO),International Confederation of Midwives(ICM),Chinese Maternal and Child Health Association(CMCHA)have actively advocated normal childbirth[[1],[2],[3]].It is proved that normal childbirth can improve birth outcomes.展开更多
Rotational Vision System(RVS)is a common active vision system with only rotational degrees of freedom.Usually,the degree of freedom for rotation is provided by the turntable and pan head.Or the hand to eye(EIH)structu...Rotational Vision System(RVS)is a common active vision system with only rotational degrees of freedom.Usually,the degree of freedom for rotation is provided by the turntable and pan head.Or the hand to eye(EIH)structure in articulated arm robots.Due to assembly deviations and manufacturing accuracy limitations,the ideal assumption that the rotation axis is fully aligned with the coordinate axis of the local camera is mostly violated.To address this issue,we propose a generalized deviation model that specifies a rotation axis that connects the rotational motion of the platform with the external orientation(EO)of the camera.On this basis,we propose a heuristic estimation algorithm to minimize global reprojection errors and fit circles in space under constraints of global optimization.The experiment shows that the translation and tilt average reprojection errors of dynamic EO reconstruction based on the reprojection error method are 0.14 and 0.08 pixels,respectively.In the absence of angle measurement,the results of the circle fitting method are similar to them(with a relative error of about 2%),meeting the application requirements of general visual measurement.展开更多
文摘Odor pollution in landfill area has attracted more social attention in China. It is very important to control the generation of odor pollutants in situ. Analyzing odorous materials production form buried waste, simulated columns of different volatile solid (VS) content and different buried period waste were designed. Gas compounds produced from the columns were collected and analyzed by comprehensive two-dimensional gas chromatography (GC × GC) method. It has remarkable relationship between VS content and concentrations of odorous material. When VS content more than 40%, the total amount of odorous compounds increases remarkably. It can be inferred that reduced VS content of original waste may effective decreasing odorous materials production in landfill area. The old rubbish produced more odorous compounds than that of fresh one in simulated columns.
基金Supported by Chongqing Municipal Key Laboratory of Institutions of Higher Education(WEPKL2013MS-10)Chongqing Municipal Innovation Planning Project for University Students in 2013(201310643003)
文摘Through a series of exploration based on PSR framework model,for the purpose of building a suitable Chongqing agricultural nonpoint source pollution evaluation index system model framework,combined with the presence of Chongqing specific agro-environmental issues,we build a agricultural non-point source pollution assessment index system,and then study the agricultural system pressure,agro-environmental status and human response in total 3 major categories,develope an agricultural non-point source pollution evaluation index consisting of 3 criteria indicators and 19 indicators. As can be seen from the analysis,pressures and responses tend to increase and decrease linearly,state and complex have large fluctuations,and their fluctuations are similar mainly due to the elimination of pressures and impact,increasing the impact for agricultural non-point source pollution.
基金supported by grants from the National Key Research and Development Program of China(Grant No.2021YFC2500400)the National Natural Science Foundation of China(Grant Nos.81974439&82204121)+2 种基金the Beijing-Tianjin-Hebei Basic Research Cooperation Special Project(20JCZXJC00090)the Tianjin Health Committee Foundation(Grant No.TJWJ2021MS008)the Tianjin Key Medical Discipline(Specialty)Construction Project(Grant No.TJYXZDXK-009A).
文摘Given the rapid changes in social structure(urbanization),economic structure(industrialization),and demographic structure(population aging)in China,cancer has become a major public health problem1.Extensive evidence has indicated that screening can decrease cancer mortality,particularly among high-risk groups,and several representative national and regional cancer screening programs have been launched in China to cope with the increasing burden of cancer.
基金Supported by The grant for Key Laboratory of Gastroenterology and Hepatology,Ministry of Health,Renji Hospital,Shanghai Jiao Tong University School of MedicineNational Natural Science Foundation of China,No.81170355
文摘AIM:To evaluate the predictive value of neutrophil infiltration as a marker of Helicobacter pylori(H.pylori) infection.METHODS:A total of 315 patients with dyspepsia symptoms who underwent upper gastrointestinal endoscopy were enrolled in this study.Biopsies were evaluated using the updated Sydney system.The medication history of all patients in the preceding 4 wk was recorded.The diagnosis of H.pylori infection was based on 13 C-urea breath test at least 4 wk after withdrawal of antisecretory drugs,antibiotics and related drugs.For the patients with subtotal gastrectomy,the diagnosis of H.pylori infection was based on anti-H.pylori immunoglobulin G(IgG) antibody.Serum anti-H.pylori IgG antibody was measured by enzyme-linked immunosorbent assays(Biohit,Finland).RESULTS:The sensitivity,specificity,positive predictive value and negative predictive value of neutrophil infiltration in the diagnosis of H.pylori infection were 92.3%,83.5%,77.4% and 94.7%,respectively.Neutrophil infiltration of gastric mucosa in the histological analysis was strongly associated with H.pylori infection(77.4% vs 5.3% in the neutrophil infiltration negative group,P = 0.000).Moderate neutrophil infiltration was more frequent in H.pylori infection when compared to mild infiltration(81.8% and 75%,respectively),but did not reach statistical significance.For those patients with negative rapid urease test,H.pylori was detected in 73.2% of patients with positive neutrophil infiltration on histology.In patients with subtotal gastrectomy,the diagnostic accuracy of neutrophil infiltration inH.pylori infection was 50%.CONCLUSION:Neutrophil infiltration is closely associated with H.pylori and may be recognized as a sign of this infection.
基金This study was supported by the National Key R&D Program of China(Grant No.2017YFA0604300)the National Natural Science Foundation of China(Grant Nos.41861144014,41775106 and U1811464)+1 种基金the Program for Guangdong Introducing Innovative and Entrepreneurial Teams(Grant No.2017ZT07X355)the project of the Chinese Ministry of Emergency Management on“Catastrophe Evaluation Modeling Study”.
文摘The prolonged mei-yu/baiu system with anomalous precipitation in the year 2020 has swollen many rivers and lakes,caused flash flooding,urban flooding and landslides,and consistently wreaked havoc across large swathes of China,particularly in the Yangtze River basin.Significant precipitation and flooding anomalies have already been seen in magnitude and extension so far this year,which have been exerting much higher pressure on emergency responses in flood control and mitigation than in other years,even though a rainy season with multiple ongoing serious flood events in different provinces is not that uncommon in China.Instead of delving into the causes of the uniqueness of this year’s extreme precipitation-flooding situation,which certainly warrants in-depth exploration,in this article we provide a short view toward a more general hydrometeorological solution to this annual nationwide problem.A“glocal”(global to local)hydrometeorological solution for floods(GHS-F)is considered to be critical for better preparedness,mitigation,and management of different types of significant precipitation-caused flooding,which happen extensively almost every year in many countries such as China,India and the United States.Such a GHS-F model is necessary from both scientific and operational perspectives,with the strength in providing spatially consistent flood definitions and spatially distributed flood risk classification considering the heterogeneity in vulnerability and resilience across the entire domain.Priorities in the development of such a GHS-F are suggested,emphasizing the user’s requirements and needs according to practical experiences with various flood response agencies.
文摘Glucocorticoids(GCs)have been the mainstay of immunosuppressive therapy in solid organ transplantation(SOT)for decades,due to their potent effects on innate immunity and tissue protective effects.However,some SOT centers are reluctant to administer GCs long-term because of the various related side effects.This review summarizes the advantages and disadvantages of GCs in SOT.PubMed and Scopus databases were searched from 2011 to April 2021 using search syntaxes covering“transplantation”and“glucocorticoids”.GCs are used in transplant recipients,transplant donors,and organ perfusate solution to improve transplant outcomes.In SOT recipients,GCs are administered as induction and maintenance immunosuppressive therapy.GCs are also the cornerstone to treat acute antibody-and T-cell-mediated rejections.Addition of GCs to organ perfusate solution and pretreatment of transplant donors with GCs are recommended by some guidelines and protocols,to reduce ischemia-reperfusion injury peri-transplant.GCs with low bioavailability and high potency for GC receptors,such as budesonide,nanoparticle-mediated targeted delivery of GCs to specific organs,and combination use of dexamethasone with inducers of immuneregulatory cells,are new methods of GC application in SOT patients to reduce side effects or induce immune-tolerance instead of immunosuppression.Various side effects involving different non-targeted organs/tissues,such as bone,cardiovascular,neuromuscular,skin and gastrointestinal tract,have been noted for GCs.There are also potential drug-drug interactions for GCs in SOT patients.
基金Supported by Research Center for Sustainable Development in Three Gorges Reservoir Area Open Fund Project(2014-sxxyjd-05)Youth Research Project of Chongqing Three Gorges University(11QN-07)Innovation Planning Project for University Students in Chongqing Three Gorges University(2014-56)
文摘Agriculture is the foundation of national economy,and agricultural development is related to the rapid development of long-term stability of the society and economy. Agriculture includes farming,forestry,animal husbandry,and fisheries. Agricultural listed company as an agricultural enterprise " leader",which directly affects the development of the entire growth of the agricultural industry development and policy,so the study of agricultural listed company's growth is particularly important. This paper uses AHP weighting method to evaluate 2012 financial data on the growth of agricultural listed companies.
基金supported by Shenzhen Science and Technology Program(Grant No.RCYX20210706092103024)two projects funded by the State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops(No.SKL2018001 to X.Z.and No.SKL20190012 to H.Z.)。
文摘Structural variants(SVs)are a type of genetic variation that contribute substantially to phenotypic diversity and evolution.Further study of SVs will help us understand the influence of SVs associated with tea quality and stress resistance and provide new insight into tea plant breeding improvement and genetic research.However,SVs have not been thoroughly discovered in the tea plant genomes.Herein,we constructed a large-scale SV map across a population of 107 resequenced genomes,including both ancient and cultivated tea plants.A total of 44,240 highconfident SVs were identified,including 34,124 DEL(deletions),4,448 DUP(duplications),2,503 INV(inversions),544 INS(insertions)and 2,621 TRA(translocations).In total,12,400 protein-coding genes were overlapped with SVs,of which 49.5%were expressed in all five tea tissues.SVbased analysis of phylogenetic relationships and population structure in tea plants showed a consistent evolutionary history with the SNP-based results.We also identified SVs subject to artificial selection and found that genes under domestication were enriched in metabolic pathways involving theanine and purine alkaloids,biosynthesis of monoterpenoid,phenylpropanoid,fatty acid,and isoflavonoid,contributing to traits of agronomic interest in tea plants.In addition,a total of 27 terpene synthase(TPS)family genes were selected during domestication.These results indicate that these SVs could provide extensive genomic information for tea quality improvement.
基金the financial support from The Strategic Priority Research Program of the Chinese Academy of Sciences(XDA14010102)Chinese National Science Foundation grants(4197306941673045)。
文摘Individual hydrocarbons identified to be macrocyclic alkanes in a torbanite from the Sydney Basin(Australia)were successfully isolated from its extracts using preparative gas chromatography and analyzed by NMR.Saturated cyclic structures were confirmed by single peaks in the NMR~1H and~(13)C spectra indicating single forms of H and C atoms exist in these biomarker molecules.This is consistent with the methylene unit in a ring system assignment of the macrocyclic alkanes and accounts for a formula of(CH2)n.The unusual molecular structures of these compounds are consistent with those that were identified from previous GC retention index data and co-injection with a standard supports the previous research.The mass spectral fragmentation behaviors of representative cyclic alkanes were further investigated by comparing them with the mass spectra of isolated individual macrocyclic alkanes.The characteristic fragment ions in the macrocyclic alkanes of(M–28)+and base peaks of m/z 97,111,125,etc.,can be assigned as being generated by simple a-/i-cleavage and hydrogen rearrangement.These fragmentation pathways combined with retention indices should assist in differentiating these compounds from monounsaturated alkenes and alkylated monocyclics having similar mass spectral characteristics in other geological samples.
基金Supported by the Natural Science Foundation of Gansu Province(No.23JRRA0942)Innovation Fund for Colleges and Universities in Gansu Province(No.2021B-23).
文摘AIM:To investigate the effect of morroniside(Mor)on lipopolysaccharide(LPS)-treated iris pigment epithelial cells(IPE).METHODS:IPE cells were induced by LPS and treated with Mor.Cell proliferation was detected by cell counting kit(CCK)-8,apoptosis was detected by flow cytometry,the levels of tumor necrosis factor-α(TNF-α),interleukin(IL)-6,and IL-8 were measured by enzyme-linked immunosorbent assay(ELISA)kits,and the protein expression of TLR4,JAK2,p-JAK2,STAT3,and p-STAT3 was analyzed by Western blotting.In addition,overexpression of TLR4 and Mor treatment of LPS-stimulated IPE cells were also tested for the above indices.RESULTS:Mor effectively promoted the proliferation and inhibited the apoptosis of LPS-treated IPE cells.In addition,Mor significantly reduced the levels of TNF-α,IL-6,and IL-8 and significantly inhibited the expression of TLR4,p-JAK2,and p-STAT3 in LPS-treated IPE cells.The effect of Mor on LPS-treated IPE cells was markedly attenuated after overexpression of TLR4.CONCLUSION:These findings suggest that Mor may ameliorate LPS-induced inflammatory damage and apoptosis in IPE through inhibition of TLR4/JAK2/STAT3 pathway.
基金This manuscript was supported by Beijing Natural Science Foundation(Grant No.7222106).
文摘In recent years,more and more attention has been paid to normal childbirth.The World Health Organization(WHO),International Confederation of Midwives(ICM),Chinese Maternal and Child Health Association(CMCHA)have actively advocated normal childbirth[[1],[2],[3]].It is proved that normal childbirth can improve birth outcomes.
基金support of the National Natural Science Foundation of China(No.52175504 and 51927811)the Fundamental Research Funds for the Central Universities of China(No.PA2022GDSK0074)the National Key Research and Development Program of China(No.2022CSJGG1303)
文摘Rotational Vision System(RVS)is a common active vision system with only rotational degrees of freedom.Usually,the degree of freedom for rotation is provided by the turntable and pan head.Or the hand to eye(EIH)structure in articulated arm robots.Due to assembly deviations and manufacturing accuracy limitations,the ideal assumption that the rotation axis is fully aligned with the coordinate axis of the local camera is mostly violated.To address this issue,we propose a generalized deviation model that specifies a rotation axis that connects the rotational motion of the platform with the external orientation(EO)of the camera.On this basis,we propose a heuristic estimation algorithm to minimize global reprojection errors and fit circles in space under constraints of global optimization.The experiment shows that the translation and tilt average reprojection errors of dynamic EO reconstruction based on the reprojection error method are 0.14 and 0.08 pixels,respectively.In the absence of angle measurement,the results of the circle fitting method are similar to them(with a relative error of about 2%),meeting the application requirements of general visual measurement.
