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MicroRNAs in hepatocellular carcinoma treatment:Charting the path forward
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作者 hong t lin Antonio F Alvarez Castaneda +1 位作者 Somashekar G Krishna Khalid Mumtaz 《World Journal of Gastroenterology》 SCIE CAS 2024年第11期1470-1474,共5页
MicroRNAs(miRNAs)are recognized for their involvement in the regulation of gene expression and exhibit significant potential in both the prognostic assessment and treatment of hepatocellular carcinoma(HCC).HCC,like ot... MicroRNAs(miRNAs)are recognized for their involvement in the regulation of gene expression and exhibit significant potential in both the prognostic assessment and treatment of hepatocellular carcinoma(HCC).HCC,like other tumors,seldom occurs in isolation;instead,it evolves within a microenvironment featuring oncogenic and tumor-suppressive elements.When combined with suitable delivery vehicles,miRNA technology provides the capability to directly engage with these elements,thereby hindering tumor formation and progression.Ongoing research in this domain holds the promise of enabling a more efficacious and multi-modal treatment approach for HCC in the near future. 展开更多
关键词 Hepatocellular carcinoma Tumor microenvironment MicroRNA Mesenchymal stem cell EXOSOME
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