Objective:To investigate the economic burden of patients with acute kidney injury(AKI)by analyzing the distribution of hospitalization expenses and its influencing factors in the Affiliated Hospital of Hebei Universit...Objective:To investigate the economic burden of patients with acute kidney injury(AKI)by analyzing the distribution of hospitalization expenses and its influencing factors in the Affiliated Hospital of Hebei University.Methods:The hospitalization information of patients with AKI from January 2020 to January 2023 was collected and sorted through the hospital charging system and the factors affecting the total hospitalization cost were analyzed by multiple linear regression.Results:Univariate analysis showed that age,occupation,marriage,length of hospitalization,recovery of renal function,and stage of AKI had significant effects on hospitalization cost(P<0.05).The result of the multiple linear regression analysis model showed that age(t=4.11,P<0.0001),length of hospitalization(t=16.10,P<0.0001),recovery of renal function(t=3.26,P<0.0001),AKI stage(t=5.23,P=0.002)are factors affecting the economic burden of patients with AKI.Conclusion:AKI patients should be managed according to age stratification to effectively control the progression of the disease and improve the quality of the medical services provided.This will reduce the economic burden of patients.展开更多
BACKGROUND Since December 2019,there have been many new cases of coronavirus pneumonia in Wuhan,Hubei Province,which has gradually spread throughout the country.AIM To explore our hospital’s innovative management sys...BACKGROUND Since December 2019,there have been many new cases of coronavirus pneumonia in Wuhan,Hubei Province,which has gradually spread throughout the country.AIM To explore our hospital’s innovative management system to ensure the efficient operation of fever clinics during the epidemic,since controlling the spread of disease is an important way to prevent and control the epidemic.METHODS In total,200 outpatients with fever at our hospital between November 2019 and July 2020 were selected and allocated into two groups.RESULTS The fever clinic in our hospital operated smoothly,and infection with the novel coronavirus disease(COVID-19)has not been reported in our hospital.Additionally,we did not have any cases of missed diagnosis.The awareness regarding COVID-19 infection sources,transmission routes,early symptoms,and preventive measures was significantly higher in our fever clinic than in those of the pre-management group.CONCLUSION"An integrated system,three separate responsibilities"ensured the efficient functioning of our fever outpatient clinic and early screening of COVID-19 cases,which effectively curbed the transmission of COVID-19 and hence prevented COVID-19 pneumonia epidemic in our hospital,ultimately achieving the maximum effect of epidemic prevention and control.展开更多
In this paper, the synthesis and crystallization behavior of poly(ether ether ketone ether ketone) (PEEKEK) are reported. PEEKEK was prepared from 4,4'-bis(p-fluorobenzoyl) diphenyl ether (4,4'-FBDE) and hydro...In this paper, the synthesis and crystallization behavior of poly(ether ether ketone ether ketone) (PEEKEK) are reported. PEEKEK was prepared from 4,4'-bis(p-fluorobenzoyl) diphenyl ether (4,4'-FBDE) and hydroquinone along the nucleophilic substitution route. The thermal properties were investigated by using DSC and TGA. The crystallization behavior of PEEKEK under several conditions, i.e., crystallization from the molten state (melt crystallization), crystallization from a quenched sample (cold crystallization) and crystallization induced by exposing glassy sample to methylene chloride (solvent-induced crystallization) has also been investigated. The results show that crystallization of PEEKEK could be induced by the above methods, and no polymorphism was found. The differences in the crystallization of PEEKEK induced by the above methods are seen in their degree of crystallinity.展开更多
Objective:The aim of this study was to explore the relationship between total dietary sugar and overweight and obesity in North China.Methods:A total of 1,074 permanent residents of Baoding,China aged 18-65 were selec...Objective:The aim of this study was to explore the relationship between total dietary sugar and overweight and obesity in North China.Methods:A total of 1,074 permanent residents of Baoding,China aged 18-65 were selected by cluster random sampling method.Relevant information was collected by questionnaires.A multiple logistics regression model was used to analyze the relationship between total dietary sugar intake and obesity-related indicators.Results:The average dietary sugar intake of residents aged between 18 and 65 in Baoding was 34.6 g per day.The average dietary total sugar intake of men was lower than that of women(28.5 g vs.37.4 g).The combined detection rate of overweight and obesity was 68.1%.After adjusting variables such as age,gender,education level,smoking,and energy intake,it was found that excessive dietary sugar intake may be a risk factor for overweight[OR(95%CI)=1.382(1.014,1.889)]and obesity[OR(95%CI):1.490(1.112,2.002)]in men.In women,only dietary sugar intake was found to be a risk factor for overweight[OR(95%CI):1.616(1.001,2.625)].Conclusion:The intake level of dietary sugar of adults in the Baoding area is high,and the problem of overweight and obesity is serious.The level of dietary total sugar intake may be a risk factor for overweight and obesity,but there are gender differences.展开更多
Because of its softness,wear resistance,biocompatibility,extremely comfortable human touch,thermoplastic vulcanizate(TPV)comprised of silicone rubber(SiR)and thermoplastic polyurethane(TPU)(SiR/TPU TPV)is especially s...Because of its softness,wear resistance,biocompatibility,extremely comfortable human touch,thermoplastic vulcanizate(TPV)comprised of silicone rubber(SiR)and thermoplastic polyurethane(TPU)(SiR/TPU TPV)is especially suitable for wearable intelligent devices.Nevertheless,developing good compatibilizer is still required to prepare high performance SiR/TPU TPV.In this study,three kinds of polyurethane-polysiloxane copolymer(PU-co-PSi)with different contents of polysiloxane segment were selected,and their compatibilization effect on SiR/TPU blends was studied using nanomechanical mapping technique of AFM.The results show that using PU-co-PSi with the highest content of polysiloxane segment(PU-co-HPSi),the interface thickness largely increases,and the average size of SiR dispersed phase largely decreases,indicating its good compatibilization effect.By using PU-co-HPSi as compatibilizer,SiR/TPU TPV with a fine SiR dispersed phase and good mechanical performance were successfully prepared.The mechanism on the compatibilization effect of these PU-co-PSi on SiR/TPU TPVs was revealed.展开更多
A new method for the formation of electroactive polyaniline （PANI） biocatalyzed by hemoglobin coupled with glucose oxidase in neutral medium on the polystyrene nanospheres （PS） modified glassy carbon electrode, wa...A new method for the formation of electroactive polyaniline （PANI） biocatalyzed by hemoglobin coupled with glucose oxidase in neutral medium on the polystyrene nanospheres （PS） modified glassy carbon electrode, was investigated. The bio-polymerized PANI formed on the PS was confirmed by the obvious increase of the diameter of the particles on the scanning electron microscopy image. The cyclic voltammetric behavior of the PANI was also investigated. PANI produced an oxidative peak at 0.28 V and a reductive peak at 0.23 V. Based on the glucose-dependent bio-polymerization, a new electrochemical protocol for the estimation of glucose was developed. The square wave voltammetric response of PANI deposited on the modified electrode increased linearly with glucose concentration in the range of 0.1- 10.0 μmol/L. The efficient performance of hemoglobin-oxidase biocatalyzed polymerization of aniline provides a new concept for the synthesis of nanomaterials, and a general protocol for the development of the biosensors.展开更多
文摘Objective:To investigate the economic burden of patients with acute kidney injury(AKI)by analyzing the distribution of hospitalization expenses and its influencing factors in the Affiliated Hospital of Hebei University.Methods:The hospitalization information of patients with AKI from January 2020 to January 2023 was collected and sorted through the hospital charging system and the factors affecting the total hospitalization cost were analyzed by multiple linear regression.Results:Univariate analysis showed that age,occupation,marriage,length of hospitalization,recovery of renal function,and stage of AKI had significant effects on hospitalization cost(P<0.05).The result of the multiple linear regression analysis model showed that age(t=4.11,P<0.0001),length of hospitalization(t=16.10,P<0.0001),recovery of renal function(t=3.26,P<0.0001),AKI stage(t=5.23,P=0.002)are factors affecting the economic burden of patients with AKI.Conclusion:AKI patients should be managed according to age stratification to effectively control the progression of the disease and improve the quality of the medical services provided.This will reduce the economic burden of patients.
基金Supported by the Zhejiang Natural Science Foundation of China,No.LGF18H030009.
文摘BACKGROUND Since December 2019,there have been many new cases of coronavirus pneumonia in Wuhan,Hubei Province,which has gradually spread throughout the country.AIM To explore our hospital’s innovative management system to ensure the efficient operation of fever clinics during the epidemic,since controlling the spread of disease is an important way to prevent and control the epidemic.METHODS In total,200 outpatients with fever at our hospital between November 2019 and July 2020 were selected and allocated into two groups.RESULTS The fever clinic in our hospital operated smoothly,and infection with the novel coronavirus disease(COVID-19)has not been reported in our hospital.Additionally,we did not have any cases of missed diagnosis.The awareness regarding COVID-19 infection sources,transmission routes,early symptoms,and preventive measures was significantly higher in our fever clinic than in those of the pre-management group.CONCLUSION"An integrated system,three separate responsibilities"ensured the efficient functioning of our fever outpatient clinic and early screening of COVID-19 cases,which effectively curbed the transmission of COVID-19 and hence prevented COVID-19 pneumonia epidemic in our hospital,ultimately achieving the maximum effect of epidemic prevention and control.
基金This project was financial supported by National Natural Science Foundation of China and the Chinese "863" High Technology Funds.
文摘In this paper, the synthesis and crystallization behavior of poly(ether ether ketone ether ketone) (PEEKEK) are reported. PEEKEK was prepared from 4,4'-bis(p-fluorobenzoyl) diphenyl ether (4,4'-FBDE) and hydroquinone along the nucleophilic substitution route. The thermal properties were investigated by using DSC and TGA. The crystallization behavior of PEEKEK under several conditions, i.e., crystallization from the molten state (melt crystallization), crystallization from a quenched sample (cold crystallization) and crystallization induced by exposing glassy sample to methylene chloride (solvent-induced crystallization) has also been investigated. The results show that crystallization of PEEKEK could be induced by the above methods, and no polymorphism was found. The differences in the crystallization of PEEKEK induced by the above methods are seen in their degree of crystallinity.
基金was funded by the research grant from the Natural Science Foundation of Hebei Province(No.H2021201054)Science and Technology Research Project of Higher Education in Hebei Province(No.QN2019130)Xingtai city key research and development plan(No.2020ZC309).
文摘Objective:The aim of this study was to explore the relationship between total dietary sugar and overweight and obesity in North China.Methods:A total of 1,074 permanent residents of Baoding,China aged 18-65 were selected by cluster random sampling method.Relevant information was collected by questionnaires.A multiple logistics regression model was used to analyze the relationship between total dietary sugar intake and obesity-related indicators.Results:The average dietary sugar intake of residents aged between 18 and 65 in Baoding was 34.6 g per day.The average dietary total sugar intake of men was lower than that of women(28.5 g vs.37.4 g).The combined detection rate of overweight and obesity was 68.1%.After adjusting variables such as age,gender,education level,smoking,and energy intake,it was found that excessive dietary sugar intake may be a risk factor for overweight[OR(95%CI)=1.382(1.014,1.889)]and obesity[OR(95%CI):1.490(1.112,2.002)]in men.In women,only dietary sugar intake was found to be a risk factor for overweight[OR(95%CI):1.616(1.001,2.625)].Conclusion:The intake level of dietary sugar of adults in the Baoding area is high,and the problem of overweight and obesity is serious.The level of dietary total sugar intake may be a risk factor for overweight and obesity,but there are gender differences.
基金financially supported by the National Natural Science Foundation of China (Nos. 51525301 and 51903009)the National Key Research & Development Plan (No. 2017YFB0307003)Chinese Scholarship Council for supporting his PhD study in Chimie Paris Tech-PSL Research University, France (No. 202106880002)
文摘Because of its softness,wear resistance,biocompatibility,extremely comfortable human touch,thermoplastic vulcanizate(TPV)comprised of silicone rubber(SiR)and thermoplastic polyurethane(TPU)(SiR/TPU TPV)is especially suitable for wearable intelligent devices.Nevertheless,developing good compatibilizer is still required to prepare high performance SiR/TPU TPV.In this study,three kinds of polyurethane-polysiloxane copolymer(PU-co-PSi)with different contents of polysiloxane segment were selected,and their compatibilization effect on SiR/TPU blends was studied using nanomechanical mapping technique of AFM.The results show that using PU-co-PSi with the highest content of polysiloxane segment(PU-co-HPSi),the interface thickness largely increases,and the average size of SiR dispersed phase largely decreases,indicating its good compatibilization effect.By using PU-co-HPSi as compatibilizer,SiR/TPU TPV with a fine SiR dispersed phase and good mechanical performance were successfully prepared.The mechanism on the compatibilization effect of these PU-co-PSi on SiR/TPU TPVs was revealed.
基金supported by the National Natural Science Foundation of China(No.20905061)
文摘A new method for the formation of electroactive polyaniline （PANI） biocatalyzed by hemoglobin coupled with glucose oxidase in neutral medium on the polystyrene nanospheres （PS） modified glassy carbon electrode, was investigated. The bio-polymerized PANI formed on the PS was confirmed by the obvious increase of the diameter of the particles on the scanning electron microscopy image. The cyclic voltammetric behavior of the PANI was also investigated. PANI produced an oxidative peak at 0.28 V and a reductive peak at 0.23 V. Based on the glucose-dependent bio-polymerization, a new electrochemical protocol for the estimation of glucose was developed. The square wave voltammetric response of PANI deposited on the modified electrode increased linearly with glucose concentration in the range of 0.1- 10.0 μmol/L. The efficient performance of hemoglobin-oxidase biocatalyzed polymerization of aniline provides a new concept for the synthesis of nanomaterials, and a general protocol for the development of the biosensors.
