BACKGROUND Cyclic vomiting syndrome(CVS)is a chronic functional gastrointestinal disorder involving the gut–brain interaction that is characterized by recurring episodes of nausea,vomiting,abdominal pain,and interspe...BACKGROUND Cyclic vomiting syndrome(CVS)is a chronic functional gastrointestinal disorder involving the gut–brain interaction that is characterized by recurring episodes of nausea,vomiting,abdominal pain,and interspersed complete normal periods.Superior mesenteric artery(SMA)syndrome(SMAS)is a vascular condition in which the horizontal portion of the duodenum is compressed due to a reduced angle between the aorta and the SMA.This condition presents with symptoms similar to CVS,posing challenges in distinguishing between the two and often resulting in misdiagnosis or inappropriate treatment.CASE SUMMARY A 20-year-old female patient presented with recurrent episodes of vomiting and experienced a persistent fear of vomiting for the past 2 years.She adopted conscious dietary restrictions,which led to severe malnutrition.Initially,she was diagnosed with SMAS,as revealed by computed tomography angiography.Despite efforts to increase the angle between the aorta and the SMA through weight gain,her vomiting did not improve.Finally,she was diagnosed with comorbidities including CVS,SMAS and anxiety disorder.She underwent comprehensive interventions,including enteral and parenteral nutritional supplementation,administration of antiemetic and anti-anxiety agents,and participation in mindfulness-based cognitive therapy.The patient eventually experienced a notable improvement in both body weight and clinical symptoms.CONCLUSION We present a rare case of CVS in an adult complicated with SMAS and propose additional treatment with nutritional support,pharmacological intervention,and psychotherapy.展开更多
Background:Schistosomiasis japonica is still endemic in the People’s Republic of China(P.R.China)in five provinces of lake and marshland regions and in two provinces of mountainous regions.Studies elucidated that ind...Background:Schistosomiasis japonica is still endemic in the People’s Republic of China(P.R.China)in five provinces of lake and marshland regions and in two provinces of mountainous regions.Studies elucidated that individual and community perception,attitudes towards schistosomiasis,and hygiene behaviors were crucial factors for preventing schistosomiasis.This study sought to assess the knowledge of,attitudes towards,and practices(KAP)relating to schistosomiasis in two subtypes of a mountainous region in Eryuan County,Yunnan Province,P.R.China.The study’s aim is to make suggestions for establishing more specific and effective control measures for disease transmission and interruption in two subtypes of a mountainous region with low-level infection rates.Methods:A cross-sectional study of 3,000 inhabitants was carried out in the Yongle(plateau basin)and Xinzhuang(plateau canyon)communities of Eryuan County,Yunnan Province in November and December 2011.Stratified cluster random sampling was undertaken using a uniform set of quantitative questionnaires administered by trained assistants.This was further supported with qualitative data from in-depth interviews(IDIs)conducted with ten farmers and ten students.All participants were examined for schistosomiasis using both a serological test(indirect hemagglutination assay[IHA])and a stool examination(Kato-Katz).Results:The total schistosomiasis knowledge rate in Yongle(83.4%)was significantly lower than that in Xinzhuang(95.5%).In both communities,among the respondents aged 15 years or below,more than one third didn’t know the name,endemic areas,and animal reservoirs of schistosomiasis.The majority of respondents in Eryuan acquired their schistosomiasis knowledge from doctors,followed by handouts and hearing from others.The infection rate was once the highest in Yongle,but is now the highest in Xinzhuang,where there are more risk factors for schistosomiasis,such as frequently grazing cattle,digging vegetables or cutting grass in the field,as well as raising cattle by free grazing.Conclusion:In short,Eryuan County’s overall knowledge rate of schistosomiasis was found to be high.Due to various dominating risk factors,different control strategies should be designed keeping in mind the two different subtypes of endemic areas for schistosomiasis in mountainous regions,namely plateau basins and plateau canyons.展开更多
Background:Schistosomiasis is a global snail-transmitted infectious disease of poverty.Transmission control had been achieved in China in 2015 after the control efforts for over 60 years.Currently,the remaining core r...Background:Schistosomiasis is a global snail-transmitted infectious disease of poverty.Transmission control had been achieved in China in 2015 after the control efforts for over 60 years.Currently,the remaining core regions endemic for Schistosoma japonicum are mainly located in the marshland and lake regions along the Yangtze River basin.Methods:During the period from 2001 through 2015,an integrated environmental improvement of the marshlands was carried out through the implementation of industrial,agricultural and resources development projects in Yizheng County along the Yangtze River.S.japonicum infection in humans,livestock and snails was estimated by serology,stool examination,hatching technique and microscopy during the 15-year study period to evaluate the effect of the integrated environmental improvement on control and elimination of schistosomiasis.Results:A 0.05%overall rate of S.japonicum infection was observed in snails during the 15-year study period,and no infected snails were detected since 2012.The overall prevalence of S.japonicum infection was 0.09%in humans during the study period,and no human infection was found since 2012.In addition,only 13 bovines were identified with S.japonicum infection in 2003 during the 15-year study period,and since 2004,no infection was found in livestock.Conclusion:The results of the present study demonstrate that the implementation of industrial,agricultural and water resources development projects,not only alters snail habitats in marshland regions,and promotes local economic development,which appears a win-to-win strategy to block the transmission of S.japonicum and accelerate socio-economic development along the Yangtze River.展开更多
基金Supported by 1·3·5 Project for Disciplines of Excellence,West China Hospital,Sichuan University,No.ZYJC21004.
文摘BACKGROUND Cyclic vomiting syndrome(CVS)is a chronic functional gastrointestinal disorder involving the gut–brain interaction that is characterized by recurring episodes of nausea,vomiting,abdominal pain,and interspersed complete normal periods.Superior mesenteric artery(SMA)syndrome(SMAS)is a vascular condition in which the horizontal portion of the duodenum is compressed due to a reduced angle between the aorta and the SMA.This condition presents with symptoms similar to CVS,posing challenges in distinguishing between the two and often resulting in misdiagnosis or inappropriate treatment.CASE SUMMARY A 20-year-old female patient presented with recurrent episodes of vomiting and experienced a persistent fear of vomiting for the past 2 years.She adopted conscious dietary restrictions,which led to severe malnutrition.Initially,she was diagnosed with SMAS,as revealed by computed tomography angiography.Despite efforts to increase the angle between the aorta and the SMA through weight gain,her vomiting did not improve.Finally,she was diagnosed with comorbidities including CVS,SMAS and anxiety disorder.She underwent comprehensive interventions,including enteral and parenteral nutritional supplementation,administration of antiemetic and anti-anxiety agents,and participation in mindfulness-based cognitive therapy.The patient eventually experienced a notable improvement in both body weight and clinical symptoms.CONCLUSION We present a rare case of CVS in an adult complicated with SMAS and propose additional treatment with nutritional support,pharmacological intervention,and psychotherapy.
基金This work was supported by theEcohealth Emerging Infectious Diseases Initiative(EcoEID),which is a CA$8.9 million global effort funded by Canada's lnternational Development Research CentreForeign Affairs,Trade and Development Canada(through the GlobalHealth Research Initiative)+3 种基金the Australian Agency for International Development(grant no.105509-00001002-024)This work was partially supported by the National Natural Science Foundation(grant no.81102173 and 81273192)the Health Promotion Project,Outstanding Person Fund,Jiangsu Provincial Department of Health(2011)the National S&T MajorProgram(grant no.2008ZX1004-011 and 2012ZX10004-220).
文摘Background:Schistosomiasis japonica is still endemic in the People’s Republic of China(P.R.China)in five provinces of lake and marshland regions and in two provinces of mountainous regions.Studies elucidated that individual and community perception,attitudes towards schistosomiasis,and hygiene behaviors were crucial factors for preventing schistosomiasis.This study sought to assess the knowledge of,attitudes towards,and practices(KAP)relating to schistosomiasis in two subtypes of a mountainous region in Eryuan County,Yunnan Province,P.R.China.The study’s aim is to make suggestions for establishing more specific and effective control measures for disease transmission and interruption in two subtypes of a mountainous region with low-level infection rates.Methods:A cross-sectional study of 3,000 inhabitants was carried out in the Yongle(plateau basin)and Xinzhuang(plateau canyon)communities of Eryuan County,Yunnan Province in November and December 2011.Stratified cluster random sampling was undertaken using a uniform set of quantitative questionnaires administered by trained assistants.This was further supported with qualitative data from in-depth interviews(IDIs)conducted with ten farmers and ten students.All participants were examined for schistosomiasis using both a serological test(indirect hemagglutination assay[IHA])and a stool examination(Kato-Katz).Results:The total schistosomiasis knowledge rate in Yongle(83.4%)was significantly lower than that in Xinzhuang(95.5%).In both communities,among the respondents aged 15 years or below,more than one third didn’t know the name,endemic areas,and animal reservoirs of schistosomiasis.The majority of respondents in Eryuan acquired their schistosomiasis knowledge from doctors,followed by handouts and hearing from others.The infection rate was once the highest in Yongle,but is now the highest in Xinzhuang,where there are more risk factors for schistosomiasis,such as frequently grazing cattle,digging vegetables or cutting grass in the field,as well as raising cattle by free grazing.Conclusion:In short,Eryuan County’s overall knowledge rate of schistosomiasis was found to be high.Due to various dominating risk factors,different control strategies should be designed keeping in mind the two different subtypes of endemic areas for schistosomiasis in mountainous regions,namely plateau basins and plateau canyons.
基金This study was supported by the grants from the National Science&Technology Pillar Program of China(grant no.2009BAI78B07)Jiangsu Provincial Department of Science and Technology(grant no.BL2014021)+1 种基金Jiangsu Provincial Young Talents in Medical Sciences(grant no.QNRC2016621)Jiangsu Department of Health(grant nos.X201408 and X201410).
文摘Background:Schistosomiasis is a global snail-transmitted infectious disease of poverty.Transmission control had been achieved in China in 2015 after the control efforts for over 60 years.Currently,the remaining core regions endemic for Schistosoma japonicum are mainly located in the marshland and lake regions along the Yangtze River basin.Methods:During the period from 2001 through 2015,an integrated environmental improvement of the marshlands was carried out through the implementation of industrial,agricultural and resources development projects in Yizheng County along the Yangtze River.S.japonicum infection in humans,livestock and snails was estimated by serology,stool examination,hatching technique and microscopy during the 15-year study period to evaluate the effect of the integrated environmental improvement on control and elimination of schistosomiasis.Results:A 0.05%overall rate of S.japonicum infection was observed in snails during the 15-year study period,and no infected snails were detected since 2012.The overall prevalence of S.japonicum infection was 0.09%in humans during the study period,and no human infection was found since 2012.In addition,only 13 bovines were identified with S.japonicum infection in 2003 during the 15-year study period,and since 2004,no infection was found in livestock.Conclusion:The results of the present study demonstrate that the implementation of industrial,agricultural and water resources development projects,not only alters snail habitats in marshland regions,and promotes local economic development,which appears a win-to-win strategy to block the transmission of S.japonicum and accelerate socio-economic development along the Yangtze River.
