Electrochromism is the process by which a material applies a small electrical signal to change the optical properties(transmittance,reflectance,absorptivity and emissivity)of the material reversibly or permanently thr...Electrochromism is the process by which a material applies a small electrical signal to change the optical properties(transmittance,reflectance,absorptivity and emissivity)of the material reversibly or permanently through REDOX reactions resulting from ion and electron embedding/ejection.Metal-organic framework(MOF)are advantageous materials for electrochromic application due to their high porosity,large specific surface area and orderly pore structure,that promotes the adsorption of electrolyte ions,ion diffusion and charge transfer.In addition,MOFs possess a variety of ligands and metal centers,allowing for design of composition types and pore structure sizes.This grants them the advantages of both organic electrochromic materials,such as vivid colors and fast color transformation,and inorganic electrochromic materials,like high coloring efficiency and excellent stability.This paper reviews the current research progress of MOF electrochromic materials,including materials design,electrochromic properties,and application.展开更多
Tumor resection causes damage in the head and neck which creates problems in swallowing, chewing, articulation, and vision, all of which seriously affect patients' quality of life. In this work, we evaluated the a...Tumor resection causes damage in the head and neck which creates problems in swallowing, chewing, articulation, and vision, all of which seriously affect patients' quality of life. In this work, we evaluated the application of a free medial tibial flap in reconstruction of head and neck defects after tumor resection. We discussed the anatomy, surgical technique, and the advantages and disadvantages of the flap. We found several benefits for the flap, such as, it is especially effective for the defects that require thin-layer epithelium to cover or the separated soft tissue defect; a two-team approach can be used because the donor site is far away from the head and neck; and the flap is easy to integrate because of the subcutaneous fat layer of the free medial tibial flap is thin and the flap is soft. Thus, the medial tibial flap could replace the forearm flap for certain applications.展开更多
Solar-driven water evaporation is considered to be a viable and very efficient technology for fresh water production.Unfortunately,the photothermal membrane has a low absorptivity,low photothermal conversion and poor ...Solar-driven water evaporation is considered to be a viable and very efficient technology for fresh water production.Unfortunately,the photothermal membrane has a low absorptivity,low photothermal conversion and poor recyclability,which are difficult to meet the demands of self-floating solar driven evaporators in practical applications.Herein,a hierarchical nanostructure Ni_(3)S_(2) has been prepared by in-situ growing method on Ni foam(NF),which shows excellent absorptivity,outstanding recyclable and high mechanically durable properties.The photothermal membrane was composed of hierarchical nanostructure Ni_(3)S_(2)@NF,which exhibited excellent solar absorption(93.13%) in the wavelength range of 250–2500 nm and sustained anti-corrosion capacity for one month.In addition,the hierarchical nanostructure Ni_(3)S_(2)@NF has good hydrophilicity and strong binding force,indicating this photothermal membrane exhibits good stability and outstanding photothermal conversion efficiency.An evaporation system based on 3D Ni_(3)S_(2)@NF membrane exhibited excellent water evaporation ability,the highest water evaporation rate(1.53 kg m^(-2)h^(-1)) and the photothermal conversion efficiency(84.7%) under 1 sun illumination.In the desalination experiment,the water evaporation rate and photothermal conversion efficiency almost keep constant over 5 cycles tests and do not decrease compared with the experiment in pure water.This result demonstrated that the Ni_(3)S_(2)@NF membrane has shown good corrosion resistance and outstanding recyclability.Due to the simple preparation method,low cost,outstanding recyclability and high mechanical durability in the sea water,this Ni_(3)S_(2)@NF membrane have great potential for long-term solar distillation applications.展开更多
The shear failure modes and respective failure mechanism of Sn3.5Ag and Sn3.0Ag0.5Cu lead-free solder bumping on Au/Ni/Cu metallization formed by induction spontaneous heating reflow process have been investigated thr...The shear failure modes and respective failure mechanism of Sn3.5Ag and Sn3.0Ag0.5Cu lead-free solder bumping on Au/Ni/Cu metallization formed by induction spontaneous heating reflow process have been investigated through the shear test after aging at 120℃ for 0, 1, 4, 9 and 16 d. Different typical shear failure behaviors have been found in the loading curves （shear force vs displacement）. From the results of interracial morphology analysis of the fracture surfaces and cross-sections, two main typical failure modes have been identified. The probabilities of the failure modes occurrence are inconsistent when the joints were aged for different times. The evolution of the brittle NiaSn4 and Cu-Ni-Au-Sn layers and the grains coarsening of the solder bulk are the basic reasons for the change of shear failure modes.展开更多
In order to optimize the network coding resources in a multicast network, an improved adaptive quantum genetic algorithm (AM-QEA) was proposed. Firstly, the optimization problem was translated into a graph decompositi...In order to optimize the network coding resources in a multicast network, an improved adaptive quantum genetic algorithm (AM-QEA) was proposed. Firstly, the optimization problem was translated into a graph decomposition problem. Then the graph decomposition problem was represented by the binary coding, which can be processed by quantum genetic algorithm. At last, a multiple-operators based adaptive quantum genetic algorithm was proposed to optimize the network coding resources. In the algorithm, the individual fitness evaluation operator and population mutation adjustment operator were employed to solve the shortcomings of common quantum genetic algorithm, such as high convergence rate, easy to fall into local optimal solution and low diversity of the population in later stage. The experimental results under various topologies show that the proposed algorithm has the advantages of high multicast success rate, fast convergence speed and strong global search ability in resolving the network coding resource optimization problems.展开更多
Knowledge transfer model of software process improvement (SPI) and the conceptual framework of influencing factors are established. The model includes five elements which are knowledge of transfer, sources of knowledg...Knowledge transfer model of software process improvement (SPI) and the conceptual framework of influencing factors are established. The model includes five elements which are knowledge of transfer, sources of knowledge, recipients of knowledge, relationship of transfer parties, and the environment of transfer. The conceptual framework includes ten key factors which are ambiguity, systematism, transfer willingness, capacity of impartation, capacity of absorption, incen-tive mechanism, culture, technical support, trust and knowledge distance. The research hypothesis is put forward. Em-pirical study concludes that the trust relationship among SPI staffs has the greatest influence on knowledge transfer, and organizational incentive mechanism can produce positive effect to knowledge transfer of SPI. Finally, some sug-gestions are put forward to improve the knowledge transfer of SPI: establishing a rational incentive mechanism, exe-cuting some necessary training to transfer parties and using software benchmarking.展开更多
Immunogenic dying tumor cells hold promising prospects as cancer vaccines to activate systemic immunity against both primary and metastatic tumors.Especially,X-ray-induced dying tumor cells are rich in highly immunoge...Immunogenic dying tumor cells hold promising prospects as cancer vaccines to activate systemic immunity against both primary and metastatic tumors.Especially,X-ray-induced dying tumor cells are rich in highly immunogenic tumor-associated antigens and self-generated dsDNA as potent adjuvants.However,we found that the X-ray induction process can result in the excessive exposure of phosphatidylserine in cancer vaccines,which can specifically bind with the MerTK receptor on macrophages,acting as a“checkpoint”to facilitate immune silence in the tumor microenvironment.Therefore,we developed a novel strategy combining X-ray-induced cancer vaccines with UNC2250,a macrophage MerTK“checkpoint inhibitor,”for treating peritoneal carcinomatosis in colon cancer.By incorporating UNC2250 into the treatment regimen,immunosuppressive efferocytosis of macrophages,which relies on MerTK-directed recognition of phosphatidylserine on vaccines,was effectively blocked.Consequently,the immune analysis revealed that this combination strategy promoted the maturation of dendritic cells and M1-like repolarization of macrophages,thereby simultaneously eliciting robust adaptive and innate immunity.This innovative approach utilizing X-ray-induced vaccines combined with a checkpoint inhibitor may provide valuable insights for developing effective cancer vaccines and immunotherapies targeting colon cancer.展开更多
Prussian blue(PB)is an anodic coloring candidate in the wide area of electrochromic(EC)applications.However,the co-influence of weak adhesion and low electrical conductivity leads to the poor stability and slow switch...Prussian blue(PB)is an anodic coloring candidate in the wide area of electrochromic(EC)applications.However,the co-influence of weak adhesion and low electrical conductivity leads to the poor stability and slow switching speed.To tackle this bottleneck,a novel TiO_(2)/Au/PB nanorod array is designed through hydrothermal and electrodeposition approaches on fluorine-doped tin oxide(FTO)glass.Such a designed ternary array structure could not only increase reactive site and conductivity,but also improve ion storage capacity and promote charge transfer,attributed to the synergistic effect of TiO_(2)/Au/PB core–shell heterostructure and the localized surface plasmon resonance(LSPR)effect of Au nanoparticles.Besides,density functional theory(DFT)calculation confirms the strong interaction between rutile TiO_(2)and FTO substrate,which contributes to the improvement of EC cycle stability.Benefiting from these effects,the TiO_(2)/Au/PB film shows a fast coloration/bleaching response of 1.08/2.01 s(2.17/4.48 s,PB film)and ultra-stable EC performance of 86.8%after 20,000 cycles(50%after 600 cycles,PB film).Furthermore,the high-intensity light source can be shot clearly by the designed and assembled EC iris device(ECID)with TiO_(2)/Au/PB film as an EC layer,while the photograph without an ECID is blurry,confirming the feasibility of the material in portable digital products.展开更多
Uniform crushed straw throwing and seed-sowing machines can achieve the processes of straw chopping,straw transport,sowing,fertilization,and straw mulching at the same time,which is widely used in many areas of China....Uniform crushed straw throwing and seed-sowing machines can achieve the processes of straw chopping,straw transport,sowing,fertilization,and straw mulching at the same time,which is widely used in many areas of China.Conveying device is one of the important components used to convey,elevate and throw straw.However,the problems of high power consumption and congestion affect the promotion of the machine.Therefore,the conveying device of uniform crushed straw throwing and seed-sowing machine was analyzed in order to determine its device operation mechanism.Kinematic and dynamic analyses of particles of crushed rice straw during lifting and dispersion are used to develop a flexible-body model of rod-shaped and agglomerate-shaped crushed straw and a coupling model including the mechanical structure of the device.By integrating computational fluid dynamics and the discrete element method,the gas-solid coupling theory in numerical simulations and motion analysis of crushed straw particles is used to determine how the flow field and motion characteristics affect the conveying performance.Besides,regression equations to describe the relationships between the factors and each assessment index were established by using the regression analysis and response surface analysis with the software Design-Expert.The effect of throwing blade speed X_(1),conveying volume of crushed straw X_(2),and pipeline diameter X_(3) on the throwing speed of crushed straw Y_(1) and specific power consumption Y2 were investigated.The highest throwing speed of crushed straw and lowest specific power consumption are the optimization goal.The results of optimization showed that the predict the best optimal parameters were 2000 r/min throwing blade rotational speed,1.4 kg/s conveying volume,and 220 mm pipeline diameter,the planter achieved a throwing speed of 12.2 m/s and specific power consumption of 9179 m^(2)/s^(2).And then a field test verification was conducted.The planter achieved a throwing speed 12.4 m/s and specific power consumption 9070 m^(2)/s^(2) while selecting the best optimal parameters.Thus,the optimal parameters can provide a high-performance operation and satisfy the actual operation requirements The results provide a theoretical basis and data support for seeding technology innovation and equipment optimization to ensure uniform crushed straw throwing in dense rice stubble fields.展开更多
Corrugated silicon nanocone(SiNC)arrays have been fabricated on a silicon wafer by two polystyrene-sphere-monolayer-masked etching steps in order to create high-performance antireflective coatings.The reflectance was ...Corrugated silicon nanocone(SiNC)arrays have been fabricated on a silicon wafer by two polystyrene-sphere-monolayer-masked etching steps in order to create high-performance antireflective coatings.The reflectance was reduced from above 35%to less than 0.7%in the range 400-1050 nm,and it remained below 0.5%at incidence angles up to 70°at 632.8 nm for both s-and p-polarized light.The fluorinated corrugated SiNC array surface exhibits superhydrophobic properties with a water contact angle of 164°.展开更多
This paper presents a winning solution for the CCKS-2020 financial event extraction task, where the goal is to identify event types, triggers and arguments in sentences across multiple event types. In this task, we fo...This paper presents a winning solution for the CCKS-2020 financial event extraction task, where the goal is to identify event types, triggers and arguments in sentences across multiple event types. In this task, we focus on resolving two challenging problems(i.e., low resources and element overlapping) by proposing a joint learning framework, named SaltyFishes. We first formulate the event extraction task as a joint probability model. By sharing parameters in the model across different types, we can learn to adapt to low-resource events based on high-resource events. We further address the element overlapping problems by a mechanism of Conditional Layer Normalization, achieving even better extraction accuracy. The overall approach achieves an F1-score of 87.8% which ranks the first place in the competition.展开更多
Traditional fluorescence enhancement based on a match of the maximum excitation or emission of fluorescence molecule with the spectra of the nanostructure can hardly enhance blue and red fluorescent molecules.Here,an ...Traditional fluorescence enhancement based on a match of the maximum excitation or emission of fluorescence molecule with the spectra of the nanostructure can hardly enhance blue and red fluorescent molecules.Here,an enhanced method which is a new strategy based on the antireflective array has been developed to enhance the emission of blue and red fluorescent molecules.The fluorescence emission is enhanced by increasing the absorption at excitation wavelengths of the fluorescent molecules and reducing the fluorescent energy dissipation with an antireflective array.By introducing the antireflective arrays,the emission enhancement of blue and red fluorescent molecules is,respectively,up to 14 and 18 fold.It is a universal and effective strategy for enhancing fluorescence emission,which could be applied to enhance the intensity of organic LED and imaging.展开更多
In the development of chemo-immunotherapy, many efforts have been focusing on designing suitable carriers to realize the co-delivery of chemotherapeutic and immunotherapeutic with different physicochemical properties ...In the development of chemo-immunotherapy, many efforts have been focusing on designing suitable carriers to realize the co-delivery of chemotherapeutic and immunotherapeutic with different physicochemical properties and mechanisms of action. Besides, rapid drug release at the tumor site with minimal drug degradation is also essential to facilitate the antitumor effect in a short time. Here, we reported a cancer cell membrane-coated pH-responsive nanogel(NG@M) to co-deliver chemotherapeutic paclitaxel(PTX) and immunotherapeutic agent interleukin-2(IL-2) under mild conditions for combinational treatment of triple-negative breast cancer. In the designed nanogels, the synthetic copolymer PDEA-co-HP-β-cyclodextrin-co-Pluronic F127 and charge reversible polymer dimethylmaleic anhydride-modified polyethyleneimine endowed nanogels with excellent drug-loading capacity and rapid responsive drug-releasing behavior under acidic tumor microenvironment. Benefited from tumor homologous targeting capacity, NG@M exhibited 4.59-fold higher accumulation at the homologous tumor site than heterologous cancer cell membrane-coated NG. Rapidly released PTX and IL-2 enhanced the maturation of dendritic cells and quickly activated the antitumor immune response in situ, followed by prompted infiltration of immune effector cells. By the combined chemo-immunotherapy, enhanced antitumor effect and efficient pulmonary metastasis inhibition were achieved with a prolonged median survival rate(39 days).展开更多
Objective:To define the properties of lung cancer cells that resisted conventionally fractionated radiation exposure.Methods:Acquired radioresistant lung cancer cell line A549 was constructed by X-ray irradiation with...Objective:To define the properties of lung cancer cells that resisted conventionally fractionated radiation exposure.Methods:Acquired radioresistant lung cancer cell line A549 was constructed by X-ray irradiation with a clinical conventional fraction dose of 2 Gy daily during 30 fractions.Cell morphology,molecular markers,migration capacity and invasion potential were evaluated by the microscope,Western blot,immunofluorescence,wound healing test and transwell chamber assay,respectively.Results:Radioresistant A549 cells shifted from an epithelial to a mesenchymal morphology,termed as epithelial-mesenchymal transition(EMT),and was accompanied by decreased expressions of epithelial markers(F=4.568,P<0.05)and increased expression of mesenchymal markers(F=4.270,P<0.05),greater migratory and invasive capabilities(t=6.386,5.644,P<0.05).The expression of TGF-β,and phosphorylated levels of Akt and Smad3 were also enhanced(F=6.496,4.685,3.370,P<0.05).Furthermore,the EMT phenotype induced by radiation could be reversed through inhibition of TGF-β,Akt or Smad3,indicating a functional relationship be-tween them.Conclusions:EMT mediates acquired radioresistance of lung cancer cells induced by IR with clinical parameters,and the crosstalk mode of TGF-β/Akt/Smad signaling plays a critical regulatory role in this process.展开更多
The urgent need for fresh water resource is a public issue facing the world.Solar distillation for seawater desalination is a promising freshwater production method.Interfacial solar evaporation systems based on 2 D p...The urgent need for fresh water resource is a public issue facing the world.Solar distillation for seawater desalination is a promising freshwater production method.Interfacial solar evaporation systems based on 2 D photo-thermal membranes have been widely studied,but salt pollution is one of the main challenges for solar distillation.In order to solve this problem,a hydrophilic three-dimensional(3 D)porous photo-thermal fiber felt(PFF)was obtained by one-step method,through a simple polydopamine(PDA)coating method with hydrophobic graphite felt as a substrate.The PFF had a good evaporation rate of 1.48 kg m^(-2)h^(-1)and its corresponding light-vapor conversion efficiency reached 87.4%.In addition,the PFF exhibited an excellent salt-resistant ability when applied to photo-thermal evaporation of highsalinity seawater with 10 wt%NaCl,owing to its intrinsic 3 D macroporous structure for the migration circulation of salt ions.The development of the PFF offers a new route for the exploration of salt-re sistant photo-thermal materials and is promising for the practical application of solar distillation.展开更多
基金the National Natural Science Foundation of China(52072096)The Natural Science Foundation of Heilongjiang Province(LH2023E034).
文摘Electrochromism is the process by which a material applies a small electrical signal to change the optical properties(transmittance,reflectance,absorptivity and emissivity)of the material reversibly or permanently through REDOX reactions resulting from ion and electron embedding/ejection.Metal-organic framework(MOF)are advantageous materials for electrochromic application due to their high porosity,large specific surface area and orderly pore structure,that promotes the adsorption of electrolyte ions,ion diffusion and charge transfer.In addition,MOFs possess a variety of ligands and metal centers,allowing for design of composition types and pore structure sizes.This grants them the advantages of both organic electrochromic materials,such as vivid colors and fast color transformation,and inorganic electrochromic materials,like high coloring efficiency and excellent stability.This paper reviews the current research progress of MOF electrochromic materials,including materials design,electrochromic properties,and application.
文摘Tumor resection causes damage in the head and neck which creates problems in swallowing, chewing, articulation, and vision, all of which seriously affect patients' quality of life. In this work, we evaluated the application of a free medial tibial flap in reconstruction of head and neck defects after tumor resection. We discussed the anatomy, surgical technique, and the advantages and disadvantages of the flap. We found several benefits for the flap, such as, it is especially effective for the defects that require thin-layer epithelium to cover or the separated soft tissue defect; a two-team approach can be used because the donor site is far away from the head and neck; and the flap is easy to integrate because of the subcutaneous fat layer of the free medial tibial flap is thin and the flap is soft. Thus, the medial tibial flap could replace the forearm flap for certain applications.
基金supported by the National Natural Science Foundation of China (No. 51571076, 21903068, 51702068, 51903068, 52072096)Open Project of State Key Laboratory of Urban Water Resource and Environment of Harbin Institute of Technology (No. HCK201716)。
文摘Solar-driven water evaporation is considered to be a viable and very efficient technology for fresh water production.Unfortunately,the photothermal membrane has a low absorptivity,low photothermal conversion and poor recyclability,which are difficult to meet the demands of self-floating solar driven evaporators in practical applications.Herein,a hierarchical nanostructure Ni_(3)S_(2) has been prepared by in-situ growing method on Ni foam(NF),which shows excellent absorptivity,outstanding recyclable and high mechanically durable properties.The photothermal membrane was composed of hierarchical nanostructure Ni_(3)S_(2)@NF,which exhibited excellent solar absorption(93.13%) in the wavelength range of 250–2500 nm and sustained anti-corrosion capacity for one month.In addition,the hierarchical nanostructure Ni_(3)S_(2)@NF has good hydrophilicity and strong binding force,indicating this photothermal membrane exhibits good stability and outstanding photothermal conversion efficiency.An evaporation system based on 3D Ni_(3)S_(2)@NF membrane exhibited excellent water evaporation ability,the highest water evaporation rate(1.53 kg m^(-2)h^(-1)) and the photothermal conversion efficiency(84.7%) under 1 sun illumination.In the desalination experiment,the water evaporation rate and photothermal conversion efficiency almost keep constant over 5 cycles tests and do not decrease compared with the experiment in pure water.This result demonstrated that the Ni_(3)S_(2)@NF membrane has shown good corrosion resistance and outstanding recyclability.Due to the simple preparation method,low cost,outstanding recyclability and high mechanical durability in the sea water,this Ni_(3)S_(2)@NF membrane have great potential for long-term solar distillation applications.
文摘The shear failure modes and respective failure mechanism of Sn3.5Ag and Sn3.0Ag0.5Cu lead-free solder bumping on Au/Ni/Cu metallization formed by induction spontaneous heating reflow process have been investigated through the shear test after aging at 120℃ for 0, 1, 4, 9 and 16 d. Different typical shear failure behaviors have been found in the loading curves （shear force vs displacement）. From the results of interracial morphology analysis of the fracture surfaces and cross-sections, two main typical failure modes have been identified. The probabilities of the failure modes occurrence are inconsistent when the joints were aged for different times. The evolution of the brittle NiaSn4 and Cu-Ni-Au-Sn layers and the grains coarsening of the solder bulk are the basic reasons for the change of shear failure modes.
文摘In order to optimize the network coding resources in a multicast network, an improved adaptive quantum genetic algorithm (AM-QEA) was proposed. Firstly, the optimization problem was translated into a graph decomposition problem. Then the graph decomposition problem was represented by the binary coding, which can be processed by quantum genetic algorithm. At last, a multiple-operators based adaptive quantum genetic algorithm was proposed to optimize the network coding resources. In the algorithm, the individual fitness evaluation operator and population mutation adjustment operator were employed to solve the shortcomings of common quantum genetic algorithm, such as high convergence rate, easy to fall into local optimal solution and low diversity of the population in later stage. The experimental results under various topologies show that the proposed algorithm has the advantages of high multicast success rate, fast convergence speed and strong global search ability in resolving the network coding resource optimization problems.
文摘Knowledge transfer model of software process improvement (SPI) and the conceptual framework of influencing factors are established. The model includes five elements which are knowledge of transfer, sources of knowledge, recipients of knowledge, relationship of transfer parties, and the environment of transfer. The conceptual framework includes ten key factors which are ambiguity, systematism, transfer willingness, capacity of impartation, capacity of absorption, incen-tive mechanism, culture, technical support, trust and knowledge distance. The research hypothesis is put forward. Em-pirical study concludes that the trust relationship among SPI staffs has the greatest influence on knowledge transfer, and organizational incentive mechanism can produce positive effect to knowledge transfer of SPI. Finally, some sug-gestions are put forward to improve the knowledge transfer of SPI: establishing a rational incentive mechanism, exe-cuting some necessary training to transfer parties and using software benchmarking.
基金This research was supported by the National Natural Science Foundation of China(No.82104098,China)the Program for HUST Academic Frontier Youth Team(No.2018QYTD13,China)+1 种基金Wuhan Science and Technology Plan(2022023702025187,China)Natural Science Foundation of Hubei Province(2023AFD152,China).
文摘Immunogenic dying tumor cells hold promising prospects as cancer vaccines to activate systemic immunity against both primary and metastatic tumors.Especially,X-ray-induced dying tumor cells are rich in highly immunogenic tumor-associated antigens and self-generated dsDNA as potent adjuvants.However,we found that the X-ray induction process can result in the excessive exposure of phosphatidylserine in cancer vaccines,which can specifically bind with the MerTK receptor on macrophages,acting as a“checkpoint”to facilitate immune silence in the tumor microenvironment.Therefore,we developed a novel strategy combining X-ray-induced cancer vaccines with UNC2250,a macrophage MerTK“checkpoint inhibitor,”for treating peritoneal carcinomatosis in colon cancer.By incorporating UNC2250 into the treatment regimen,immunosuppressive efferocytosis of macrophages,which relies on MerTK-directed recognition of phosphatidylserine on vaccines,was effectively blocked.Consequently,the immune analysis revealed that this combination strategy promoted the maturation of dendritic cells and M1-like repolarization of macrophages,thereby simultaneously eliciting robust adaptive and innate immunity.This innovative approach utilizing X-ray-induced vaccines combined with a checkpoint inhibitor may provide valuable insights for developing effective cancer vaccines and immunotherapies targeting colon cancer.
基金Funds for the Central Universities(Nos.HIT.OCEF.2021004 and FRFCU5710090220).
文摘Prussian blue(PB)is an anodic coloring candidate in the wide area of electrochromic(EC)applications.However,the co-influence of weak adhesion and low electrical conductivity leads to the poor stability and slow switching speed.To tackle this bottleneck,a novel TiO_(2)/Au/PB nanorod array is designed through hydrothermal and electrodeposition approaches on fluorine-doped tin oxide(FTO)glass.Such a designed ternary array structure could not only increase reactive site and conductivity,but also improve ion storage capacity and promote charge transfer,attributed to the synergistic effect of TiO_(2)/Au/PB core–shell heterostructure and the localized surface plasmon resonance(LSPR)effect of Au nanoparticles.Besides,density functional theory(DFT)calculation confirms the strong interaction between rutile TiO_(2)and FTO substrate,which contributes to the improvement of EC cycle stability.Benefiting from these effects,the TiO_(2)/Au/PB film shows a fast coloration/bleaching response of 1.08/2.01 s(2.17/4.48 s,PB film)and ultra-stable EC performance of 86.8%after 20,000 cycles(50%after 600 cycles,PB film).Furthermore,the high-intensity light source can be shot clearly by the designed and assembled EC iris device(ECID)with TiO_(2)/Au/PB film as an EC layer,while the photograph without an ECID is blurry,confirming the feasibility of the material in portable digital products.
基金supported by the earmarked fund for CARS-13Natural Science Foundation of Jiangsu Province (Grant No.BK20221187).
文摘Uniform crushed straw throwing and seed-sowing machines can achieve the processes of straw chopping,straw transport,sowing,fertilization,and straw mulching at the same time,which is widely used in many areas of China.Conveying device is one of the important components used to convey,elevate and throw straw.However,the problems of high power consumption and congestion affect the promotion of the machine.Therefore,the conveying device of uniform crushed straw throwing and seed-sowing machine was analyzed in order to determine its device operation mechanism.Kinematic and dynamic analyses of particles of crushed rice straw during lifting and dispersion are used to develop a flexible-body model of rod-shaped and agglomerate-shaped crushed straw and a coupling model including the mechanical structure of the device.By integrating computational fluid dynamics and the discrete element method,the gas-solid coupling theory in numerical simulations and motion analysis of crushed straw particles is used to determine how the flow field and motion characteristics affect the conveying performance.Besides,regression equations to describe the relationships between the factors and each assessment index were established by using the regression analysis and response surface analysis with the software Design-Expert.The effect of throwing blade speed X_(1),conveying volume of crushed straw X_(2),and pipeline diameter X_(3) on the throwing speed of crushed straw Y_(1) and specific power consumption Y2 were investigated.The highest throwing speed of crushed straw and lowest specific power consumption are the optimization goal.The results of optimization showed that the predict the best optimal parameters were 2000 r/min throwing blade rotational speed,1.4 kg/s conveying volume,and 220 mm pipeline diameter,the planter achieved a throwing speed of 12.2 m/s and specific power consumption of 9179 m^(2)/s^(2).And then a field test verification was conducted.The planter achieved a throwing speed 12.4 m/s and specific power consumption 9070 m^(2)/s^(2) while selecting the best optimal parameters.Thus,the optimal parameters can provide a high-performance operation and satisfy the actual operation requirements The results provide a theoretical basis and data support for seeding technology innovation and equipment optimization to ensure uniform crushed straw throwing in dense rice stubble fields.
基金This work was supported by the National Natural Science Foundation of China(No.20373019)the Program for New Century Excellent Talents in University,and the National Basic Research Program(Nos.2007CB808003 and 2009CB939701).
文摘Corrugated silicon nanocone(SiNC)arrays have been fabricated on a silicon wafer by two polystyrene-sphere-monolayer-masked etching steps in order to create high-performance antireflective coatings.The reflectance was reduced from above 35%to less than 0.7%in the range 400-1050 nm,and it remained below 0.5%at incidence angles up to 70°at 632.8 nm for both s-and p-polarized light.The fluorinated corrugated SiNC array surface exhibits superhydrophobic properties with a water contact angle of 164°.
基金This work is supported by the National Key Research and Development Program of China(No.2016YFB1000105)the National Natural Science Foundation of China(No.61772151)+1 种基金This work’s computing device is also supported by Beijing Advanced Innovation Center of Big Data and Brain Computing,Beihang UniversityThe author Shu Guo is supported by“Zhizi Program”.
文摘This paper presents a winning solution for the CCKS-2020 financial event extraction task, where the goal is to identify event types, triggers and arguments in sentences across multiple event types. In this task, we focus on resolving two challenging problems(i.e., low resources and element overlapping) by proposing a joint learning framework, named SaltyFishes. We first formulate the event extraction task as a joint probability model. By sharing parameters in the model across different types, we can learn to adapt to low-resource events based on high-resource events. We further address the element overlapping problems by a mechanism of Conditional Layer Normalization, achieving even better extraction accuracy. The overall approach achieves an F1-score of 87.8% which ranks the first place in the competition.
基金This work was supported by the National Natural Science Foundation of China(Nos.51702068,21673096,and 21273092)the China Postdoctoral Science Foundation(No.2016M601427)Heilongjiang Province Postdoctoral Science Foundation(No.LBH-Z16080).
文摘Traditional fluorescence enhancement based on a match of the maximum excitation or emission of fluorescence molecule with the spectra of the nanostructure can hardly enhance blue and red fluorescent molecules.Here,an enhanced method which is a new strategy based on the antireflective array has been developed to enhance the emission of blue and red fluorescent molecules.The fluorescence emission is enhanced by increasing the absorption at excitation wavelengths of the fluorescent molecules and reducing the fluorescent energy dissipation with an antireflective array.By introducing the antireflective arrays,the emission enhancement of blue and red fluorescent molecules is,respectively,up to 14 and 18 fold.It is a universal and effective strategy for enhancing fluorescence emission,which could be applied to enhance the intensity of organic LED and imaging.
基金supported by National Natural Science Foundation of China (81673374,China)Program for HUST Academic Frontier Youth Team (2018QYTD13,China)Natural Science Foundation of Hubei Province (2020CFB301,China)。
文摘In the development of chemo-immunotherapy, many efforts have been focusing on designing suitable carriers to realize the co-delivery of chemotherapeutic and immunotherapeutic with different physicochemical properties and mechanisms of action. Besides, rapid drug release at the tumor site with minimal drug degradation is also essential to facilitate the antitumor effect in a short time. Here, we reported a cancer cell membrane-coated pH-responsive nanogel(NG@M) to co-deliver chemotherapeutic paclitaxel(PTX) and immunotherapeutic agent interleukin-2(IL-2) under mild conditions for combinational treatment of triple-negative breast cancer. In the designed nanogels, the synthetic copolymer PDEA-co-HP-β-cyclodextrin-co-Pluronic F127 and charge reversible polymer dimethylmaleic anhydride-modified polyethyleneimine endowed nanogels with excellent drug-loading capacity and rapid responsive drug-releasing behavior under acidic tumor microenvironment. Benefited from tumor homologous targeting capacity, NG@M exhibited 4.59-fold higher accumulation at the homologous tumor site than heterologous cancer cell membrane-coated NG. Rapidly released PTX and IL-2 enhanced the maturation of dendritic cells and quickly activated the antitumor immune response in situ, followed by prompted infiltration of immune effector cells. By the combined chemo-immunotherapy, enhanced antitumor effect and efficient pulmonary metastasis inhibition were achieved with a prolonged median survival rate(39 days).
基金supported by grants from the National Natural Science Foundation of China(No.31200633)Anhui Provincial Natural Science Foundation(No.2008085MH245)+2 种基金Excellent Young Talent Support Project of Anhui Educational Committee(No.GXYQ2019036)Natural Science Research Project of Anhui Educational Committee(No.KJ2018A0241)512 Talent Project and Natural Science Foundation of Bengbu Medical College(No.BY51201211,BYKY1725ZD).
文摘Objective:To define the properties of lung cancer cells that resisted conventionally fractionated radiation exposure.Methods:Acquired radioresistant lung cancer cell line A549 was constructed by X-ray irradiation with a clinical conventional fraction dose of 2 Gy daily during 30 fractions.Cell morphology,molecular markers,migration capacity and invasion potential were evaluated by the microscope,Western blot,immunofluorescence,wound healing test and transwell chamber assay,respectively.Results:Radioresistant A549 cells shifted from an epithelial to a mesenchymal morphology,termed as epithelial-mesenchymal transition(EMT),and was accompanied by decreased expressions of epithelial markers(F=4.568,P<0.05)and increased expression of mesenchymal markers(F=4.270,P<0.05),greater migratory and invasive capabilities(t=6.386,5.644,P<0.05).The expression of TGF-β,and phosphorylated levels of Akt and Smad3 were also enhanced(F=6.496,4.685,3.370,P<0.05).Furthermore,the EMT phenotype induced by radiation could be reversed through inhibition of TGF-β,Akt or Smad3,indicating a functional relationship be-tween them.Conclusions:EMT mediates acquired radioresistance of lung cancer cells induced by IR with clinical parameters,and the crosstalk mode of TGF-β/Akt/Smad signaling plays a critical regulatory role in this process.
基金the National Natural Science Foundation of China(No.52070052)Natural Science Foundation of Heilongjiang Province(No.YQ2020B003)+1 种基金the State Key Laboratory of Urban Water Resource and Environment(HIT,No 2021TS03)National Science and Technology Major Project(No.2017ZX07501002)。
文摘The urgent need for fresh water resource is a public issue facing the world.Solar distillation for seawater desalination is a promising freshwater production method.Interfacial solar evaporation systems based on 2 D photo-thermal membranes have been widely studied,but salt pollution is one of the main challenges for solar distillation.In order to solve this problem,a hydrophilic three-dimensional(3 D)porous photo-thermal fiber felt(PFF)was obtained by one-step method,through a simple polydopamine(PDA)coating method with hydrophobic graphite felt as a substrate.The PFF had a good evaporation rate of 1.48 kg m^(-2)h^(-1)and its corresponding light-vapor conversion efficiency reached 87.4%.In addition,the PFF exhibited an excellent salt-resistant ability when applied to photo-thermal evaporation of highsalinity seawater with 10 wt%NaCl,owing to its intrinsic 3 D macroporous structure for the migration circulation of salt ions.The development of the PFF offers a new route for the exploration of salt-re sistant photo-thermal materials and is promising for the practical application of solar distillation.
