期刊文献+
共找到1篇文章
< 1 >
每页显示 20 50 100
Antibacterial and Antibiotic-Potentiation Activities of Some Cameroonian Food Plants against Multi-Drug Resistant Gram-Negative Bacteria 被引量:7
1
作者 Simplice B.Tankeo Stephen T.Lacmata +3 位作者 Jaures A.K.Noumedem jean p.dzoyem Jules R Kuiate Victor Kuete 《Chinese Journal of Integrative Medicine》 SCIE CAS 2014年第7期546-554,共9页
Objective: To evaluate the in vitro antibacterial properties and the ability to potentiate some common antibiotics effects of the methanol extracts of 11 Cameroonian food plants on 29 Gram-negative bacteria expressin... Objective: To evaluate the in vitro antibacterial properties and the ability to potentiate some common antibiotics effects of the methanol extracts of 11 Cameroonian food plants on 29 Gram-negative bacteria expressing multidrug resistant (MDR) phenotypes. Methods: The antimicrobial activity of the extracts was performed using the broth microdilution method. The phytochemical screening of these extracts was also performed using standard methods. Resalts: Ocimum basilicum, Gnetum africanum and Eucalyptus robusta extracts possessed an antibacterial activity against all the 29 studied bacteria. The extracts from G. africanum and E. robusta were the most active with the lowest minimal inhibitory concentration of 64 p, g/mL on Escherichia coil AG100A for both extracts and also against Klebsiella pneumoniae K24 for G. africanum. When tested in the presence of phenylalanine-arginine 13 -Naphtylamide (PA 13 N), an efflux pump inhibitor, the extract of Thymus vulgafis and E. Robusta showed the best activities on most tested strains. E. Robusta extract showed good synergistic effects, improving the activity of commonly used antibiotics in about 85% of cases. Coaclasion: The overall results obtained provide the baseline information for the use of the tested plants in the treatment of bacterial infections. 展开更多
关键词 food plants Cameroon multidrug resistant Gram-negative bacteria efflux pumps
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部