目的比较鼻内镜辅助下低温等离子技术与传统唇龈沟入路在鼻前庭囊肿手术中的疗效。方法收集2013年1月-2016年11月在右江民族医学院附属医院耳鼻咽喉头颈外科收住的鼻前庭囊肿患者共38例,分为对照组20例和实验组18例,对照组采用唇龈沟入...目的比较鼻内镜辅助下低温等离子技术与传统唇龈沟入路在鼻前庭囊肿手术中的疗效。方法收集2013年1月-2016年11月在右江民族医学院附属医院耳鼻咽喉头颈外科收住的鼻前庭囊肿患者共38例,分为对照组20例和实验组18例,对照组采用唇龈沟入路手术,实验组采用鼻内镜辅助下低温等离子消融,比较两组患者手术时间、术中出血量、术后住院时间、术后并发症以及复发情况等。结果实验组与对照组比较,平均手术时间减少[(65.45±27.51)vs(34.72±17.61)min,P=0.000]、术中出血量减少[(22.35±18.41)vs(3.17±1.69)ml,P=0.000]、术后住院时间缩短[(6.35±0.75)vs(3.61±1.19)d,P=0.000]和术后并发症减少(16 vs 1,P=0.000),两组复发情况差异无统计学意义(1 vs 0,P=0.783)。结论鼻内镜辅助下低温等离子技术治疗鼻前庭囊肿相对于传统唇龈沟入路,具有时间短、创伤小、恢复快、操作简单和疗效好的优势,值得推广。展开更多
Objective To explore the optimum condition for complex enzyme-assisted extraction of galanthamine from Lycoris aurea by L_9（3~4） orthogonal array design and separation effect of cation exchange resin on galanthamine...Objective To explore the optimum condition for complex enzyme-assisted extraction of galanthamine from Lycoris aurea by L_9（3~4） orthogonal array design and separation effect of cation exchange resin on galanthamine. Methods Cellulase and pectinase solution was used as the extraction solvent. The effects of p H value of enzyme, amount of complex enzyme, dissociation time, and enzymatic hydrolysis temperature on the extraction results were investigated. Results The optimal conditions were obtained as follows： ratio of solid to liquid（g：mL） 1：10, pH value 4.5, amount of complex enzymes 4%, enzymatic hydrolysis temperature 50oC, and reaction time 2.0 h. Under these conditions, the extraction yield of galanthamine was 0.0294%. In addition, D-001 cation exchange resin was selected for separation of galanthamine. The separation conditions were that adsorption flow rate was 3 BV/h with reagent of pH2 and the desorption flow rate was 3 BV/h with 70% ethanol solution containing 1.5 mol/L ammonia. After separation, the content of galanthamine was increased to 12.31%. Conclusion The results provide a reference for industrial production of galanthamine.展开更多
文摘目的比较鼻内镜辅助下低温等离子技术与传统唇龈沟入路在鼻前庭囊肿手术中的疗效。方法收集2013年1月-2016年11月在右江民族医学院附属医院耳鼻咽喉头颈外科收住的鼻前庭囊肿患者共38例,分为对照组20例和实验组18例,对照组采用唇龈沟入路手术,实验组采用鼻内镜辅助下低温等离子消融,比较两组患者手术时间、术中出血量、术后住院时间、术后并发症以及复发情况等。结果实验组与对照组比较,平均手术时间减少[(65.45±27.51)vs(34.72±17.61)min,P=0.000]、术中出血量减少[(22.35±18.41)vs(3.17±1.69)ml,P=0.000]、术后住院时间缩短[(6.35±0.75)vs(3.61±1.19)d,P=0.000]和术后并发症减少(16 vs 1,P=0.000),两组复发情况差异无统计学意义(1 vs 0,P=0.783)。结论鼻内镜辅助下低温等离子技术治疗鼻前庭囊肿相对于传统唇龈沟入路,具有时间短、创伤小、恢复快、操作简单和疗效好的优势,值得推广。
基金Hunan Provincial Science and Technology Department(2012TP4002-3)Zhangjiajie Science and Technology Bureau(2014YB17)
文摘Objective To explore the optimum condition for complex enzyme-assisted extraction of galanthamine from Lycoris aurea by L_9（3~4） orthogonal array design and separation effect of cation exchange resin on galanthamine. Methods Cellulase and pectinase solution was used as the extraction solvent. The effects of p H value of enzyme, amount of complex enzyme, dissociation time, and enzymatic hydrolysis temperature on the extraction results were investigated. Results The optimal conditions were obtained as follows： ratio of solid to liquid（g：mL） 1：10, pH value 4.5, amount of complex enzymes 4%, enzymatic hydrolysis temperature 50oC, and reaction time 2.0 h. Under these conditions, the extraction yield of galanthamine was 0.0294%. In addition, D-001 cation exchange resin was selected for separation of galanthamine. The separation conditions were that adsorption flow rate was 3 BV/h with reagent of pH2 and the desorption flow rate was 3 BV/h with 70% ethanol solution containing 1.5 mol/L ammonia. After separation, the content of galanthamine was increased to 12.31%. Conclusion The results provide a reference for industrial production of galanthamine.
