Many existing intelligent recognition technologies require huge datasets for model learning.However,it is not easy to collect rectal cancer images,so the performance is usually low with limited training samples.In add...Many existing intelligent recognition technologies require huge datasets for model learning.However,it is not easy to collect rectal cancer images,so the performance is usually low with limited training samples.In addition,traditional rectal cancer staging is time-consuming,error-prone,and susceptible to physicians’subjective awareness as well as professional expertise.To settle these deficiencies,we propose a novel deep-learning model to classify the rectal cancer stages of T2 and T3.First,a novel deep learning model(RectalNet)is constructed based on residual learning,which combines the squeeze-excitation with the asymptotic output layer and new cross-convolution layer links in the residual block group.Furthermore,a two-stage data augmentation is designed to increase the number of images and reduce deep learning’s dependence on the volume of data.The experiment results demonstrate that the proposed method is superior to many existing ones,with an overall accuracy of 0.8583.Oppositely,other traditional techniques,such as VGG16,DenseNet121,EL,and DERNet,have an average accuracy of 0.6981,0.7032,0.7500,and 0.7685,respectively.展开更多
Use of nonlinearconductive SiC/silicone rubber(SR)field grading material(FGM)can improve the local field concentration of composite insulators.Adding large volume fraction and large-size SiC particles(SiCp)into SR can...Use of nonlinearconductive SiC/silicone rubber(SR)field grading material(FGM)can improve the local field concentration of composite insulators.Adding large volume fraction and large-size SiC particles(SiCp)into SR can obtain a good field grading effect,but it is accompanied by the deterioration of mechanical properties.Compounding SiC with different shapes can solve this contradiction.By incorporating one-dimensional SiC whiskers(SiCw)to synergize with granular SiCp,SiC/SR FGM with better field-dependent conductivity,mechanical properties and thermal conductivity than large-size SiCp and large volume fraction filling case can be obtained by using smaller size SiCp and lower filling contents.The simulations of 500 kv line insulators show that the modified SiC/SR FGM can reduce the maximum field strength along the insulator surface and at sheath-core rod interfaces by 55%and 71.4%,respectively.The combined application of FGM and grading ring can achieve a complementary effect.Using FGM to partially replace the role of the grading rings,the field strength indicators can still meet the operational requirements after the tube radius and shielding depth of the grading rings at both ends are reduced by 36.2%and 40%separately,which is a benefit to alleviating the problems of high weight and large volume faced by traditional field grading methods.展开更多
The root nodule is a complex symbiotic nitrogen fixation factory,in which cells are highly heterogeneous.However,the differentiation trajectories and interconnection of nodule cells remain largely unknown.In this stud...The root nodule is a complex symbiotic nitrogen fixation factory,in which cells are highly heterogeneous.However,the differentiation trajectories and interconnection of nodule cells remain largely unknown.In this study,we set up a modified protocol for nodule protoplast preparation and performed a single-cell RNA sequencing profiling of the indeterminate Medicago truncatula nodule.We designated 13 cell clusters with specific expression patterns in 14-day post inoculation nodules and constructed a spatial and functional cellular map based on experimental data and bioinformatic analyses.Pseudotime analysis further revealed that two groups of apical meristematic cells develop into symbiotic and un-symbiotic fate cells along their particular trajectories.Biofunction analysis of each cell cluster revealed their particularity and interrelation,especially that the un-infected cells in nitrogen fixation zone are also involved in nitrogen assimilation by undertaking the asparagine synthesis.Collectively,our data offer an important resource for investigating the mechanism of nodule organogenesis and symbiotic nitrogen fixation.展开更多
基金supported in part by the National Natural Science Foundation of China under Grants 62172192,U20A20228,and 62171203in part by the 2018 Six Talent Peaks Project of Jiangsu Province under Grant XYDXX-127in part by the Science and Technology Demonstration Project of Social Development of Jiangsu Province under Grant BE2019631.
文摘Many existing intelligent recognition technologies require huge datasets for model learning.However,it is not easy to collect rectal cancer images,so the performance is usually low with limited training samples.In addition,traditional rectal cancer staging is time-consuming,error-prone,and susceptible to physicians’subjective awareness as well as professional expertise.To settle these deficiencies,we propose a novel deep-learning model to classify the rectal cancer stages of T2 and T3.First,a novel deep learning model(RectalNet)is constructed based on residual learning,which combines the squeeze-excitation with the asymptotic output layer and new cross-convolution layer links in the residual block group.Furthermore,a two-stage data augmentation is designed to increase the number of images and reduce deep learning’s dependence on the volume of data.The experiment results demonstrate that the proposed method is superior to many existing ones,with an overall accuracy of 0.8583.Oppositely,other traditional techniques,such as VGG16,DenseNet121,EL,and DERNet,have an average accuracy of 0.6981,0.7032,0.7500,and 0.7685,respectively.
基金supported by Science and Technology Project of State Grid Corporation of China(7000-202158440A-0-0-00)。
文摘Use of nonlinearconductive SiC/silicone rubber(SR)field grading material(FGM)can improve the local field concentration of composite insulators.Adding large volume fraction and large-size SiC particles(SiCp)into SR can obtain a good field grading effect,but it is accompanied by the deterioration of mechanical properties.Compounding SiC with different shapes can solve this contradiction.By incorporating one-dimensional SiC whiskers(SiCw)to synergize with granular SiCp,SiC/SR FGM with better field-dependent conductivity,mechanical properties and thermal conductivity than large-size SiCp and large volume fraction filling case can be obtained by using smaller size SiCp and lower filling contents.The simulations of 500 kv line insulators show that the modified SiC/SR FGM can reduce the maximum field strength along the insulator surface and at sheath-core rod interfaces by 55%and 71.4%,respectively.The combined application of FGM and grading ring can achieve a complementary effect.Using FGM to partially replace the role of the grading rings,the field strength indicators can still meet the operational requirements after the tube radius and shielding depth of the grading rings at both ends are reduced by 36.2%and 40%separately,which is a benefit to alleviating the problems of high weight and large volume faced by traditional field grading methods.
基金This research was funded by National KeyResearch&Development Program of China(2022YFA0912100)National Natural Science Foundation of China(32070272)Key Projects in Science and Technology of Inner Mongolia(2021ZD0031).
文摘The root nodule is a complex symbiotic nitrogen fixation factory,in which cells are highly heterogeneous.However,the differentiation trajectories and interconnection of nodule cells remain largely unknown.In this study,we set up a modified protocol for nodule protoplast preparation and performed a single-cell RNA sequencing profiling of the indeterminate Medicago truncatula nodule.We designated 13 cell clusters with specific expression patterns in 14-day post inoculation nodules and constructed a spatial and functional cellular map based on experimental data and bioinformatic analyses.Pseudotime analysis further revealed that two groups of apical meristematic cells develop into symbiotic and un-symbiotic fate cells along their particular trajectories.Biofunction analysis of each cell cluster revealed their particularity and interrelation,especially that the un-infected cells in nitrogen fixation zone are also involved in nitrogen assimilation by undertaking the asparagine synthesis.Collectively,our data offer an important resource for investigating the mechanism of nodule organogenesis and symbiotic nitrogen fixation.
