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Molecular mechanisms underlying microglial sensing and phagocytosis in synaptic pruning 被引量:1
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作者 Anran Huo jiali wang +6 位作者 Qi Li Mengqi Li Yuwan Qi Qiao Yin Weifeng Luo Jijun Shi Qifei Cong 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第6期1284-1290,共7页
Microglia are the main non-neuronal cells in the central nervous system that have important roles in brain development and functional connectivity of neural circuits.In brain physiology,highly dynamic microglial proce... Microglia are the main non-neuronal cells in the central nervous system that have important roles in brain development and functional connectivity of neural circuits.In brain physiology,highly dynamic microglial processes are facilitated to sense the surrounding environment and stimuli.Once the brain switches its functional states,microglia are recruited to specific sites to exert their immune functions,including the release of cytokines and phagocytosis of cellular debris.The crosstalk of microglia between neurons,neural stem cells,endothelial cells,oligodendrocytes,and astrocytes contributes to their functions in synapse pruning,neurogenesis,vascularization,myelination,and blood-brain barrier permeability.In this review,we highlight the neuron-derived“find-me,”“eat-me,”and“don't eat-me”molecular signals that drive microglia in response to changes in neuronal activity for synapse refinement during brain development.This review reveals the molecular mechanism of neuron-microglia interaction in synaptic pruning and presents novel ideas for the synaptic pruning of microglia in disease,thereby providing important clues for discovery of target drugs and development of nervous system disease treatment methods targeting synaptic dysfunction. 展开更多
关键词 COMPLEMENT immune signals microglia molecular signal synapse elimination synapse formation synapse refinement synaptic pruning
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A cascade of in situ conversion of bicarbonate to CO_(2) and CO_(2) electroreduction in a flow cell with a Ni-N-S catalyst
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作者 Linghui Kong Min wang +6 位作者 Yongxiao Tuo Shanshan Zhou Jinxiu wang Guangbo Liu Xuejing Cui jiali wang Luhua Jiang 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第1期183-193,I0005,共12页
Combination of CO_(2) capture using inorganic alkali with subsequently electrochemical conversion of the resultant HCO_(3)^(-)to high-value chemicals is a promising route of low cost and high efficiency.The electroche... Combination of CO_(2) capture using inorganic alkali with subsequently electrochemical conversion of the resultant HCO_(3)^(-)to high-value chemicals is a promising route of low cost and high efficiency.The electrochemical reduction of HCO_(3)^(-)is challenging due to the inaccessible of negatively charged molecular groups to the electrode surface.Herein,we adopt a comprehensive strategy to tackle this challenge,i.e.,cascade of in situ chemical conversion of HCO_(3)^(-)to CO_(2) and CO_(2) electrochemical reduction in a flow cell.With a tailored Ni-N-S single atom catalyst(SACs),where sulfur(S)atoms located in the second shell of Ni center,the CO_(2)electroreduction(CO_(2)ER)to CO is boosted.The experimental results and density functional theory(DFT)calculations reveal that the introduction of S increases the p electron density of N atoms near Ni atom,thereby stabilizing^(*)H over N and boosting the first proton coupled electron transfer process of CO_(2)ER,i.e.,^(*)+e^(-)+^(*)H+^(*)CO_(2)→^(*)COOH.As a result,the obtained catalyst exhibits a high faradaic efficiency(FE_(CO)~98%)and a low overpotential of 425 mV for CO production as well as a superior turnover frequency(TOF)of 47397 h^(-1),outcompeting most of the reported Ni SACs.More importantly,an extremely high FECOof 90%is achieved at 50 mA cm^(-2)in the designed membrane electrode assembly(MEA)cascade electrolyzer fed with liquid bicarbonate.This work not only highlights the significant role of the second coordination on the first coordination shell of the central metal for CO_(2)ER,but also provides an alternative and feasible strategy to realize the electrochemical conversion of HCO_(3)^(-)to high-value chemicals. 展开更多
关键词 S doped Ni-N-C single atom catalysts CO_(2)electrochemical reduction DFT calculations Membrane electrode assembly Reduction of bicarbonate
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High formability Mg-Zn-Gd wire facilitates ACL reconstruction via its swift degradation to accelerate intra-tunnel endochondral ossification
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作者 Xuan He Ye Li +14 位作者 Hongwei Miao Jiankun Xu Michael Tim-yun Ong Chenmin wang Lizhen Zheng jiali wang Le Huang Haiyue Zu Zhi Yao Jie Mi Bingyang Dai Xu Li Patrick Shu-hang Yung Guangyin Yuan Ling Qin 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第1期295-315,共21页
After reconstructing the anterior cruciate ligament(ACL),unsatisfactory bone tendon interface healing may often induce tunnel enlargement at the early healing stage.With good biological features and high formability,M... After reconstructing the anterior cruciate ligament(ACL),unsatisfactory bone tendon interface healing may often induce tunnel enlargement at the early healing stage.With good biological features and high formability,Magnesium-Zinc-Gadolinium(ZG21)wires are developed to bunch the tendon graft for matching the bone tunnel during transplantation.Microstructure,tensile strength,degradation,and cytotoxicity of ZG21 wire are evaluated.The rabbit model is used for assessing the biological effects of ZG21 wire by Micro-CT,histology,and mechanical test.The SEM/EDS,immunochemistry,and in vitro assessments are performed to investigate the underlying mechanism.Material tests demonstrate the high formability of ZG21 wire as surgical suture.Micro-CT shows ZG21 wire degradation accelerates tunnel bone formation,and histologically with earlier and more fibrocartilage regeneration at the healing interface.The mechanical test shows higher ultimate load in the ZG21 group.The SEM/EDS presents ZG21 wire degradation triggered calcium phosphate(Ca-P)deposition.IHC results demonstrate upregulation of Wnt3a,BMP2,and VEGF at the early phase and TGFβ3 and Type II collagen at the late phase of healing.In vitro tests also confirmed the Ca-P in the metal extract could elevate the expression of Wnt3a,βcatenin,ocn and opn to stimulate osteogenesis.Ex vivo tests of clinical samples indicated suturing with ZG21 wire did not weaken the ultimate loading of human tendon tissue.In conclusion,the ZG21 wire is feasible for tendon graft bunching.Its degradation products accelerated intra-tunnel endochondral ossification at the early healing stage and therefore enhanced bone-tendon interface healing in ACL reconstruction. 展开更多
关键词 Magnesium wire ACL reconstruction Magnesium alloy BIOMATERIALS Endochondral ossification
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A review of Vietanna(Hemiptera:Cicadidae)with descriptions of two new species from China
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作者 jiali wang Lei FENG +1 位作者 Jinyuan JIANG Cong WEI 《Entomotaxonomia》 CSCD 2024年第3期228-240,共13页
The cicada genus Vietanna is reviewed based on the descriptions of two new species,V.perparva sp.nov.and V.longiloba sp.nov.,from China.The relationship of this genus to related taxa is discussed based on the phylogen... The cicada genus Vietanna is reviewed based on the descriptions of two new species,V.perparva sp.nov.and V.longiloba sp.nov.,from China.The relationship of this genus to related taxa is discussed based on the phylogeny of Vietanna and representative species from subtribes Puranina,Leptopsaltriina,Euterpnosiina and Leptosemiina based on the mitochondrial gene COI and nuclear genes EF-1αand ARD1. 展开更多
关键词 CICADOIDEA Cicadinae Leptopsaltrini revision PHYLOGENY
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Prediction of Grinding Force by an Electroplated Grinding Wheel with Orderly-Micro-Grooves
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作者 Cong Mao jiali wang +7 位作者 Mingjun Zhang Xincheng wang Yuanqiang Luo Weidong Tang Kun Tang Zhuming Bi Yongle Hu Zhenheng Lin 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2023年第4期56-66,共11页
The ability to predict a grinding force is important to control,monitor,and optimize the grinding process.Few theoretical models were developed to predict grinding forces when a structured wheel was used in a grinding... The ability to predict a grinding force is important to control,monitor,and optimize the grinding process.Few theoretical models were developed to predict grinding forces when a structured wheel was used in a grinding process.This paper aimed to establish a single-grit cutting force model to predict the ploughing,friction and cutting forces in a grinding process.It took into the consideration of actual topography of the grinding wheel,and a theoretical grinding force model for grinding hardened AISI 52100 by the wheel with orderly-micro-grooves was proposed.The model was innovative in the sense that it represented the random thickness of undeformed chips by a probabilistic expression,and it reflected the microstructure characteristics of the structured wheel explicitly.Note that the microstructure depended on the randomness of the protruding heights and distribution density of the grits over the wheel.The proposed force prediction model was validated by surface grinding experiments,and the results showed(1)a good agreement of the predicted and measured forces and(2)a good agreement of the changes of the grinding forces along with the changes of grinding parameters in the prediction model and experiments.This research proposed a theoretical grinding force model of an electroplated grinding wheel with orderly-micro-grooves which is accurate,reliable and effective in predicting grinding forces. 展开更多
关键词 Electroplated grinding wheel Orderly-micro-grooves Grinding force Force prediction Undeformed chip thickness Experimental validation
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Multi-View & Transfer Learning for Epilepsy Recognition Based on EEG Signals
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作者 jiali wang Bing Li +7 位作者 Chengyu Qiu Xinyun Zhang Yuting Cheng Peihua wang Ta Zhou Hong Ge Yuanpeng Zhang Jing Cai 《Computers, Materials & Continua》 SCIE EI 2023年第6期4843-4866,共24页
Epilepsy is a central nervous system disorder in which brain activity becomes abnormal.Electroencephalogram(EEG)signals,as recordings of brain activity,have been widely used for epilepsy recognition.To study epilep-ti... Epilepsy is a central nervous system disorder in which brain activity becomes abnormal.Electroencephalogram(EEG)signals,as recordings of brain activity,have been widely used for epilepsy recognition.To study epilep-tic EEG signals and develop artificial intelligence(AI)-assist recognition,a multi-view transfer learning(MVTL-LSR)algorithm based on least squares regression is proposed in this study.Compared with most existing multi-view transfer learning algorithms,MVTL-LSR has two merits:(1)Since traditional transfer learning algorithms leverage knowledge from different sources,which poses a significant risk to data privacy.Therefore,we develop a knowledge transfer mechanism that can protect the security of source domain data while guaranteeing performance.(2)When utilizing multi-view data,we embed view weighting and manifold regularization into the transfer framework to measure the views’strengths and weaknesses and improve generalization ability.In the experimental studies,12 different simulated multi-view&transfer scenarios are constructed from epileptic EEG signals licensed and provided by the Uni-versity of Bonn,Germany.Extensive experimental results show that MVTL-LSR outperforms baselines.The source code will be available on https://github.com/didid5/MVTL-LSR. 展开更多
关键词 Multi-view learning transfer learning least squares regression EPILEPSY EEG signals
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Cloning and Function Identification of a Phytoene Desaturase Gene from Eucommia ulmoides
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作者 jiali wang Xiangmei Chen +2 位作者 Xiaozhen Huang Yichen Zhao Degang Zhao 《Phyton-International Journal of Experimental Botany》 SCIE 2023年第5期1377-1389,共13页
The phytoene desaturase(PDS)encodes a crucial enzyme in the carotenoid biosynthesis pathway.Silencing or inhibiting PDS expression leads to the appearance of mottled,chlorosis,or albino leaves.In this study,the CDS se... The phytoene desaturase(PDS)encodes a crucial enzyme in the carotenoid biosynthesis pathway.Silencing or inhibiting PDS expression leads to the appearance of mottled,chlorosis,or albino leaves.In this study,the CDS sequence of EuPDS(Eucommia ulmoides Phytoene Desaturase)was first cloned and then PDS was silenced in Nicotiana benthamiana.Result showed the expression level of EuPDS in leaves was higher than that in the roots and stems.In N.benthamiana leaves,which were treated by Agrobacterium for 24 h,photo-bleaching was shown on the fresh leaves one week after injection and the transcript level of PDS was down-regulated during the period of emersion.This suggested that EuPDS could silence PDS of N.benthamiana,so as to cause the phenotype of leaf whitening.PDS is the main reporter gene involved in virus-induced gene silencing(VIGS).This study offered molecular evidence for identifying PDS gene involved in Carotenoid’s biosynthesis pathway and the regulation networks in E.ulmides.It also laid a useful foundation for study on leaf discoloration mechanism of other woody plants. 展开更多
关键词 Eucommia ulmoides EuPDS virus-induced gene silencing TRV relative expression
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我国电子商务上市公司运营效率评价研究
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作者 王嘉丽 薛力闻 《工信财经科技》 2023年第5期106-120,共15页
我国电子商务产业规模巨大,成为驱动国民经济与社会发展的新引擎。本文以45家电子商务上市公司为研究对象,从Wind中获取2017—2019年公司财务数据,应用DEA-BCC模型和DEA-Malmquist指数模型进行效率测算。研究发现:电子商务上市公司整体... 我国电子商务产业规模巨大,成为驱动国民经济与社会发展的新引擎。本文以45家电子商务上市公司为研究对象,从Wind中获取2017—2019年公司财务数据,应用DEA-BCC模型和DEA-Malmquist指数模型进行效率测算。研究发现:电子商务上市公司整体运营效率仍需提升,其中产业电商与跨境电商运营效率高于零售电商与生活服务电商;多数公司不同程度存在投入资源冗余现象。技术进步指数不高、传统电商转型面临阻碍,是电商上市公司运营效率偏低的重要因素。为提升电商上市公司运营效率,应以产业电商为发展动能提升运营效率,以核心技术为发展导向优化管理体系,以社交电商为营销策略重塑消费体验。 展开更多
关键词 电子商务 数字经济 运营效率 DEA-MALMQUIST
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浅析心血管医院规划与建设方案——以中国医学科学院阜外医院深圳医院三期项目为例
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作者 汪嘉利 朱明君 +1 位作者 李影 吴伟清 《工程设计与施工》 2023年第12期45-47,共3页
心血管疾病具有突发性、紧急性、严重性特点,是居民疾病死亡的首要原因之一。论文结合目前公立医院发展及建设背景,从“心系自然,守护健康”建筑设计理念、“协调、平衡、融合”功能布局思路以及多层叠加“十字立体”交通流线规划三个... 心血管疾病具有突发性、紧急性、严重性特点,是居民疾病死亡的首要原因之一。论文结合目前公立医院发展及建设背景,从“心系自然,守护健康”建筑设计理念、“协调、平衡、融合”功能布局思路以及多层叠加“十字立体”交通流线规划三个方面分析中国医学科学院阜外医院深圳医院项目规划建设工作要点,通过实例剖析以期为心血管医疗设施规划及建设提供有价值的参考。 展开更多
关键词 心血管病医院 综合规划 人性化设计
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浅谈“三合一”制度下公立医院建设前期管理
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作者 汪嘉利 朱明君 +1 位作者 李影 吴伟清 《工程设计与施工》 2023年第4期22-24,共3页
“十四五”期间,在财政资金有限的情况下,政府投资不断增大,新一轮医院的建设工作和管理思路发生了较大转变,从而也引起了医院项目建设前期管理的变化。论文紧扣深圳市委市政府关于医疗卫生项目基建、设备、信息化“三合一”“固投与开... “十四五”期间,在财政资金有限的情况下,政府投资不断增大,新一轮医院的建设工作和管理思路发生了较大转变,从而也引起了医院项目建设前期管理的变化。论文紧扣深圳市委市政府关于医疗卫生项目基建、设备、信息化“三合一”“固投与开办费一体化”审批的工作要求,结合公立医院项目前期建设特点,分析了医院前期管理工作要点,并提出提升医院前期管理工作建议,以期为“三合一”审批制度下公立医院建设项目前期管理工作提供有价值的参考。 展开更多
关键词 政府投资项目 公立医院 前期管理
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Enhancing Capacitance Performance of Ti3C2Tx MXene as Electrode Materials of Supercapacitor: From Controlled Preparation to Composite Structure Construction 被引量:14
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作者 Xiaobei Zang jiali wang +5 位作者 Yijiang Qin Teng wang Chengpeng He Qingguo Shao Hongwei Zhu Ning Cao 《Nano-Micro Letters》 SCIE EI CAS CSCD 2020年第6期152-175,共24页
Ti3C2Tx,a novel two-dimensional layer material,is widely used as electrode materials of supercapacitor due to its good metal conductivity,redox reaction active surface,and so on.However,there are many challenges to be... Ti3C2Tx,a novel two-dimensional layer material,is widely used as electrode materials of supercapacitor due to its good metal conductivity,redox reaction active surface,and so on.However,there are many challenges to be addressed which impede Ti3C2Tx obtaining the ideal specific capacitance,such as restacking,re-crushing,and oxidation of titanium.Recently,many advances have been proposed to enhance capacitance performance of Ti3C2Tx.In this review,recent strategies for improving specific capacitance are summarized and compared,for example,film formation,surface modification,and composite method.Furthermore,in order to comprehend the mechanism of those efforts,this review analyzes the energy storage performance in different electrolytes and influencing factors.This review is expected to predict redouble research direction of Ti3C2Tx materials in supercapacitors. 展开更多
关键词 Ti3C2Tx MXene CAPACITANCE performance STORAGE mechanism ELECTRODE materials SUPERCAPACITOR
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Cooperative and Competitive Multi-Agent Systems:From Optimization to Games 被引量:11
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作者 Jianrui wang Yitian Hong +4 位作者 jiali wang Jiapeng Xu Yang Tang Qing-Long Han Jürgen Kurths 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2022年第5期763-783,共21页
Multi-agent systems can solve scientific issues related to complex systems that are difficult or impossible for a single agent to solve through mutual collaboration and cooperation optimization.In a multi-agent system... Multi-agent systems can solve scientific issues related to complex systems that are difficult or impossible for a single agent to solve through mutual collaboration and cooperation optimization.In a multi-agent system,agents with a certain degree of autonomy generate complex interactions due to the correlation and coordination,which is manifested as cooperative/competitive behavior.This survey focuses on multi-agent cooperative optimization and cooperative/non-cooperative games.Starting from cooperative optimization,the studies on distributed optimization and federated optimization are summarized.The survey mainly focuses on distributed online optimization and its application in privacy protection,and overviews federated optimization from the perspective of privacy protection me-chanisms.Then,cooperative games and non-cooperative games are introduced to expand the cooperative optimization problems from two aspects of minimizing global costs and minimizing individual costs,respectively.Multi-agent cooperative and non-cooperative behaviors are modeled by games from both static and dynamic aspects,according to whether each player can make decisions based on the information of other players.Finally,future directions for cooperative optimization,cooperative/non-cooperative games,and their applications are discussed. 展开更多
关键词 Cooperative games counterfactual regret minimization distributed optimization federated optimization fictitious
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Prevalence and control of hypertension in the elderly:results from China hypertension survey,2012-2015 被引量:3
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作者 Zengwu wang Suning Li +7 位作者 Linfeng Zhang Xin wang ZuoChen Ying Dong Congyi Zheng jiali wang Yuting Kang Runlin Gao 《中国循环杂志》 CSCD 北大核心 2018年第S01期113-113,共1页
Objective To evaluate the prevalence,awareness,treatment and control rate of hypertension among elder population in China.Methods Data form a cross-sectional stratified multistage random sampling survey conducted from... Objective To evaluate the prevalence,awareness,treatment and control rate of hypertension among elder population in China.Methods Data form a cross-sectional stratified multistage random sampling survey conducted from 2012 to 2015 were used to analyzed.Finally,a total of 134,397 participants aged≥60 years were enrolled in our study.Hypertension was defined as systolic BP≥140 mmHg,and/or diastolic BP≥90 mmHg,and/or use of antihypertensive medicine within 2 weeks.Among participants with hypertension,control rate of hypertension was defined as the participant presenting as hypertensive,but with a systolic BP measure less than 140 mm Hg and diastolic BP measure less than 90 mm Hg. 展开更多
关键词 PREVALENCE AWARENESS treatment control ELDER POPULATION
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Dimension-Enhanced Ultra-High Performance Liquid Chromatography/Ion Mobility-Quadrupole Time-of-Flight Mass Spectrometry Combined with Intelligent Peak Annotation for the Rapid Characterization of the Multiple Components from Seeds of Descurainia sophia 被引量:1
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作者 Simiao wang Xue Li +7 位作者 Boxue Chen Shitong Li jiali wang Jing wang Mingshuo Yang Xiaoyan Xu Hongda wang Wenzhi Yang 《Phyton-International Journal of Experimental Botany》 SCIE 2022年第3期541-567,共27页
The complex composition of herbal metabolites necessitates the development of powerful analytical techniques aimed to identify the bioactive components.The seeds of Descurainia sophia(SDS)are utilized in China as a co... The complex composition of herbal metabolites necessitates the development of powerful analytical techniques aimed to identify the bioactive components.The seeds of Descurainia sophia(SDS)are utilized in China as a cough and asthma relieving agent.Herein,a dimension-enhanced integral approach,by combining ultra-high performance liquid chromatography/ion mobility-quadrupole time-of-flight mass spectrometry(UHPLC/IMQTOF-MS)and intelligent peak annotation,was developed to rapidly characterize the multicomponents from SDS.Good chromatographic separation was achieved within 38 min on a UPLC CSH C18(2.1×100 mm,1.7μm)column which was eluted by 0.1%formic acid in water(water phase)and acetonitrile(organic phase).Collision-induced dissociation-MS^(2)data were acquired by the data-independent high-definition MS^(E)(HDMS^(E))in both the negative and positive electrospray ionization modes.A major components knockout strategy was applied to improve the characterization of those minor ingredients by enhancing the injection volume.Moreover,a self-built chemistry library was established,which could be matched by the UNIFI software enabling automatic peak annotation of the obtained HDMS^(E)data.As a result of applying the intelligent peak annotation workflows and further confirmation process,a total of 53 compounds were identified or tentatively characterized from the SDS,including 29 flavonoids,one uridine derivative,four glucosides,one lignin,one phenolic compound,and 17 others.Notably,four-dimensional information related to the structure(e.g.,retention time,collision cross section,MS^(1)and MS^(2)data)was obtained for each component by the developed integral approach,and the results would greatly benefit the quality control of SDS. 展开更多
关键词 Descurainia sophia multicomponent characterization ultra-high performance liquid chromatography ion mobility/quadrupole time-of-flight mass spectrometry high-definition MS^(E) flavonoid
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Photometric Redshifts and Galaxy Clusters for DES DR2, DESI DR9, and HSC-SSP PDR3 Data
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作者 Hu Zou Jipeng Sui +8 位作者 Suijian Xue Xu Zhou Jun Ma Zhimin Zhou Jundan Nie Tianmeng Zhang Lu Feng Zhixia Shen jiali wang 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2022年第6期1-21,共21页
Photometric redshift(photoz)is a fundamental parameter for multi-wavelength photometric surveys,while galaxy clusters are important cosmological probes and ideal objects for exploring the dense environmental impact on... Photometric redshift(photoz)is a fundamental parameter for multi-wavelength photometric surveys,while galaxy clusters are important cosmological probes and ideal objects for exploring the dense environmental impact on galaxy evolution.We extend our previous work on estimating photoz and detecting galaxy clusters to the latest data releases of the Dark Energy Spectroscopic Instrument(DESI)imaging surveys,Dark Energy Survey(DES)and Hyper Suprime-Cam Subaru Strategic Program(HSC-SSP)imaging surveys and make corresponding catalogs publicly available for more extensive scientific applications.The photoz catalogs include accurate measurements of photoz and stellar mass for about 320,293and 134 million galaxies with r<23,i<24 and i<25 in DESI DR9,DES DR2 and HSC-SSP PDR3 data,respectively.The photoz accuracy is about 0.017,0.024 and 0.029 and the general redshift coverage is z<1,z<1.2 and z<1.6,respectively for those three surveys.The uncertainty of the logarithmic stellar mass that is inferred from stellar population synthesis fitting is about 0.2 dex.With the above photoz catalogs,galaxy clusters are detected using a fast cluster-finding algorithm.A total of 532,810,86,963 and 36,566 galaxy clusters with the number of members larger than 10 is discovered for DESI,DES and HSC-SSP,respectively.Their photoz accuracy is at the level of 0.01.The total mass of our clusters is also estimated by using the calibration relations between the optical richness and the mass measurement from X-ray and radio observations.The photoz and cluster catalogs are available at Science DB(https://www.doi.org/10.11922/sciencedb.o00069.00003)and Paper Data Repository(https://doi.org/10.12149/101089). 展开更多
关键词 GALAXIES CLUSTERS general-galaxies distances and redshifts-galaxies PHOTOMETRY
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The prevalence of hypertension overweight/obesity and its relation with cardiovascular disease among middle-aged Chinese population
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作者 Haizhou Yao Ying Dong +6 位作者 Zengwu wang Xin wang Zuo Chen Linfeng Zhang Congyi Zheng jiali wang Yuting Kang 《中国循环杂志》 CSCD 北大核心 2018年第S01期115-115,共1页
Objective To investigate the prevalence of hypertension overweight/obesity and the combined effect on the incidence of cardiovascular disease(CVD).Methods The study population(aged from 35 to 64)were selected from 9 r... Objective To investigate the prevalence of hypertension overweight/obesity and the combined effect on the incidence of cardiovascular disease(CVD).Methods The study population(aged from 35 to 64)were selected from 9 regions of China by cluster sampling method.The baseline was conducted in 2010,and the follow-up survey was done in 2017.Participants with 24≤BMI28 kg/m^2 was defined as overweight,BMI≥28 kg/m^2 was defined as obesity. 展开更多
关键词 HYPERTENSION OVERWEIGHT/OBESITY CARDIOVASCULAR disease(CVD) cluster sampling method
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A Probe into the Reform of Land Requisition Compensation System: Based on the Survey of Rural Areas in Anhui Province
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作者 Liuzhong CHEN Zhongxiang YU jiali wang 《Asian Agricultural Research》 2015年第1期71-73 79,79,共4页
Using stakeholder survey,documentation and policy analysis,through the survey of stakeholders,this paper aims to explore the problems in the collectively owned land requisition compensation system and their causes,and... Using stakeholder survey,documentation and policy analysis,through the survey of stakeholders,this paper aims to explore the problems in the collectively owned land requisition compensation system and their causes,and put forth the reform ideas and measures to provide a reference for the development of new urbanization. The results show that there are some problems in the current land requisition compensation system,such as improper land requisition compensation standard and calculation method,low compensation standard,unsound social security system,irrational compensation and placement methods and low satisfaction of farmers whose land is requisitioned. Therefore,it is necessary to accelerate the reform of land requisition compensation system and smooth progress of new urbanization construction in accordance with the requirements of 3rd Plenum of the 18 th Communist Party of China(CPC). 展开更多
关键词 LAND REQUISITION COMPENSATION COMPENSATION and PLA
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毛建草愈伤组织诱导及植株再生
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作者 田旭平 岳康杰 +3 位作者 王佳丽 刘慧欣 史子尹 亢红伟 《植物学报》 CAS CSCD 北大核心 2024年第4期613-625,共13页
毛建草(Dracocephalumrupestre)是一种重要的药用植物。然而,其叶片外植体再生系统尚未建立。以毛建草大田叶片和组培苗叶片为外植体,探讨植物生长调节剂对愈伤组织诱导和分化、不定芽增殖及生根的影响,建立了叶片离体再生体系。结果表... 毛建草(Dracocephalumrupestre)是一种重要的药用植物。然而,其叶片外植体再生系统尚未建立。以毛建草大田叶片和组培苗叶片为外植体,探讨植物生长调节剂对愈伤组织诱导和分化、不定芽增殖及生根的影响,建立了叶片离体再生体系。结果表明,大田叶片愈伤组织诱导的最适培养基为MS+1.0 mg·L^(-1)6-BA+0.1 mg·L^(-1)2,4-D+1.0 mg·L^(-1)IAA,诱导率达84.51%,不定芽分化最佳培养基为MS+3.0 mg·L^(-1)6-BA+0.5 mg·L^(-1)TDZ+0.5 mg·L^(-1)IAA,分化率为66.37%;组培苗叶片愈伤组织诱导的最适培养基为MS+2.0mg·L^(-1)6-BA+0.1mg·L^(-1)2,4-D+0.5mg·L^(-1)IAA,诱导率达86.73%,不定芽分化最佳培养基为MS+2.0mg·L^(-1)6-BA+2.0mg·L^(-1)TDZ+0.05mg·L^(-1)IAA,分化率为53.48%。不定芽增殖适宜培养基为MS+2.0mg·L^(-1)6-BA+0.05mg·L^(-1)NAA,增殖率为83.57%,最适生根培养基为1/2MS+0.1mg·L^(-1)NAA+0.1mg·L^(-1)IBA,生根率为86.97%;在草炭:蛭石=1:1(v/v)的混合基质中组培苗长势最好。该研究建立了毛建草叶片离体培养再生体系,为毛建草种质资源保存和种苗快繁提供了技术支持。 展开更多
关键词 毛建草 愈伤组织诱导 分化 增殖 生根
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Rapid Profiling and Characterization of the Multicomponents from the Root and Rhizome of Salvia miltiorrhiza by Ultra-High Performance Liquid Chromatography/Ion Mobility-Quadrupole Time-of-Flight Mass Spectrometry in Combination with Computational Peak Annotation Workflows
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作者 Boxue Chen Hongda wang +7 位作者 Meiyu Liu Wandi Hu Yuexin Qian jiali wang Jie Liu Xue Li Jing wang Wenzhi Yang 《Phyton-International Journal of Experimental Botany》 SCIE 2022年第5期1073-1088,共16页
Herbal components characterization represents a challenging task because of the co-existing of multiple classes of naturally occurring compounds with wide spans of polarity,molecular mass,and the ubiquitous isomerism.... Herbal components characterization represents a challenging task because of the co-existing of multiple classes of naturally occurring compounds with wide spans of polarity,molecular mass,and the ubiquitous isomerism.The root and rhizome of Salvia miltiorrhiza have been utilized as a reputable traditional Chinese medicine Salviae Miltiorrhizae Radix et Rhizoma(Dan-Shen)in the treatment of cardiovascular disease.Herein,a dimensionenhanced ultra-high performance liquid chromatography/ion mobility/quadrupole time-of-flight mass spectrometry approach in combination with intelligent peak annotation workflows was established aimed to rapidly characterize the multicomponents from S.miltiorrhiza.Due to the sufficient optimization,satisfactory chromatography separation was enabled on an HSS T3 column within 33 min using 0.1%formic acid in water(A)and acetonitrile(B)as the mobile phase,while the data-independent HDMS^(E) in both the negative and positive electrospray ionization modes was utilized for the high-coverage MS^(2) data acquisition.Streamlined automatic peak annotation by searching an in-house library(recording 198 known compounds)followed by the subsequent confirming steps(e.g.,comparison with the reference compounds,fragmentation pathways analysis,and retention behavior comparison,etc.),allowed us to identify or tentatively characterize a total of 86 components(including 50 terpenoids,21 phenolic acids,and 15 others)from S.miltiorrhiza.Importantly,three-dimensional structure information,such as the retention time,MS^(1) and MS^(2) data,and collision cross section(CCS),was provided,which can facilitate the more reliable characterization of herbal components. 展开更多
关键词 Ultra-high perform liquid chromatography/ion mobility/quadrupole time-of-flight mass spectrometry highdefinition MS^(E) automatic peak annotation Salvia miltiorrhiza phenolic acid TANSHINONE
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TiO_(2)@V_(2)O_(5)空心纳米球催化剂增强MgH_(2)体系储氢性能
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作者 史柯柯 刘木子 +6 位作者 刘芳 田甜 王佳丽 陈伟 刘光 宋宇飞 李晋平 《科学通报》 EI CAS CSCD 北大核心 2024年第14期1923-1933,共11页
氢化镁(MgH_(2))是一种具有高储氢容量(7.6 wt%)的固态储氢材料,但其热力学稳定性高,动力学缓慢,限制了广泛应用.双金属氧化物催化剂对MgH_(2)储氢性能的积极影响已被许多研究者认可.本文采用简便的方法合成了具有纳米空心球结构的TiO_(... 氢化镁(MgH_(2))是一种具有高储氢容量(7.6 wt%)的固态储氢材料,但其热力学稳定性高,动力学缓慢,限制了广泛应用.双金属氧化物催化剂对MgH_(2)储氢性能的积极影响已被许多研究者认可.本文采用简便的方法合成了具有纳米空心球结构的TiO_(2)@V_(2)O_(5)双金属氧化物催化剂.添加12 wt%TiO_(2)@V_(2)O_(5)后,MgH_(2)的起始解吸温度显著降低至204℃.在100℃条件下,MgH_(2)在15 min内吸附4.21 wt%的H_(2),在300℃条件下释放6.18 wt%的H_(2),MgH_(2)的活化能从142.78 kJ/mol降低到86.47 kJ/mol.差示扫描量热分析(differential scanning calorimeter,DSC)结果表明,MgH_(2)的氢解吸活化能从197 kJ/mol降低到76.32 kJ/mol.在300℃下循环30次后,储氢量可保持98.49%.研究表明,钛价态的可逆变化和还原金属V的催化作用改善了MgH_(2)动力学及稳定性. 展开更多
关键词 氢化镁 二氧化钛 五氧化二钒 动力学性能 循环稳定性
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