Qi is the core concept that runs through the theory of traditional Chinese medicine.It is the basic connection between ancient philosophy and traditional Chinese medicine.It is the most difficult and most key point of...Qi is the core concept that runs through the theory of traditional Chinese medicine.It is the basic connection between ancient philosophy and traditional Chinese medicine.It is the most difficult and most key point of students’learning.Considering the characteristics of the course and the cognitive style of students,we use constructivist cognitive theory as a reference to design progressive teaching of the Qi content included in the course textbook.The process consists of two parts.The first part is the construction of the basic theory.Students are guided as they build schemata of basic concepts to assemble a deep understanding.They then take the initiative,and participate in the explanation,thereby completely internalizing the knowledge.The second part of the process is clinical skill training in collecting,sorting and writing medical records.In the end we have achieved the teaching goal of driving students’interest in learning,providing them with basic theoretical knowledge,and exercising the comprehensive practical problem solving skills,while cultivating the style of thinking required by practitioners of traditional Chinese medicine.展开更多
The hepatoprotective and antioxidant activities of the n-butanol extract of Rubus parvifolius L. （RPL）, a widely used medicinal plant, were evaluated. Results demonstrated that RPL extract possessed pronounced hepat...The hepatoprotective and antioxidant activities of the n-butanol extract of Rubus parvifolius L. （RPL）, a widely used medicinal plant, were evaluated. Results demonstrated that RPL extract possessed pronounced hepatoprotective effects against carbon tetrachloride （CCI4）-induced hepatic injury in mice, which was at least partially attributed to its strong antioxidant capacity. Treatment with RPL extract markedly attenuated the increases in serum alanine ami- notransferase （ALT） and aspartate aminotransferase （AST） levels caused by CCI4 intoxication. It also significantly prevented the decrease in superoxide dismutase （SOD） activity and the increase in malondialdehyde （MDA） content of liver tissue. Meanwhile, histopathological changes of hepatic damage were also remarkably ameliorated. Phytochemical analysis based on high-performance liquid chromatography/tandem mass spectrometry （HPLC-MS/MS） revealed the presence of various phenolic compounds, including caffeic acid conjugates, ellagic acid glycosides, and flavonol glycosides, which might be responsible for the hepatoprotective and antioxidant activities of RPL.展开更多
文摘Qi is the core concept that runs through the theory of traditional Chinese medicine.It is the basic connection between ancient philosophy and traditional Chinese medicine.It is the most difficult and most key point of students’learning.Considering the characteristics of the course and the cognitive style of students,we use constructivist cognitive theory as a reference to design progressive teaching of the Qi content included in the course textbook.The process consists of two parts.The first part is the construction of the basic theory.Students are guided as they build schemata of basic concepts to assemble a deep understanding.They then take the initiative,and participate in the explanation,thereby completely internalizing the knowledge.The second part of the process is clinical skill training in collecting,sorting and writing medical records.In the end we have achieved the teaching goal of driving students’interest in learning,providing them with basic theoretical knowledge,and exercising the comprehensive practical problem solving skills,while cultivating the style of thinking required by practitioners of traditional Chinese medicine.
基金supported by the National Natural Science Foundation of China (Nos. 21072174, 30873430, and 30973933)the Zhejiang Provincial Program for the Cultivation of High-Level Innovative Health Talent Fellowship, China
文摘The hepatoprotective and antioxidant activities of the n-butanol extract of Rubus parvifolius L. （RPL）, a widely used medicinal plant, were evaluated. Results demonstrated that RPL extract possessed pronounced hepatoprotective effects against carbon tetrachloride （CCI4）-induced hepatic injury in mice, which was at least partially attributed to its strong antioxidant capacity. Treatment with RPL extract markedly attenuated the increases in serum alanine ami- notransferase （ALT） and aspartate aminotransferase （AST） levels caused by CCI4 intoxication. It also significantly prevented the decrease in superoxide dismutase （SOD） activity and the increase in malondialdehyde （MDA） content of liver tissue. Meanwhile, histopathological changes of hepatic damage were also remarkably ameliorated. Phytochemical analysis based on high-performance liquid chromatography/tandem mass spectrometry （HPLC-MS/MS） revealed the presence of various phenolic compounds, including caffeic acid conjugates, ellagic acid glycosides, and flavonol glycosides, which might be responsible for the hepatoprotective and antioxidant activities of RPL.
