Loss of neurons and disruption of neural circuits are associated with many neurological diseases,including neurodegenerative diseases and mental disorders.The most prevalent pathological feature of neurodegenerative d...Loss of neurons and disruption of neural circuits are associated with many neurological diseases,including neurodegenerative diseases and mental disorders.The most prevalent pathological feature of neurodegenerative diseases is the aggregate loss of certain neuronal populations.For example,the loss of dopamine(DA)neurons in the substantia nigra pars compacta has been defined as a pathological hallmark of Parkinson’s disease(PD;Kamath et al.,2022).展开更多
With the depletion of shallow resources,the exploration of deep earth resources has become a global strategy.The study of the different patterns in the physical mechanical properties of rocks at different occurrence d...With the depletion of shallow resources,the exploration of deep earth resources has become a global strategy.The study of the different patterns in the physical mechanical properties of rocks at different occurrence depths is the basis for exploring deep into the earth,with the core and premise being the acquisition and testing of deep in-situ core specimens.Based on the original idea of deep in-situ condition preserved coring(ICP-Coring)and testing,combined with theoretical modeling,numerical analysis,test platform development,indoor testing and engineering application,the principles and technologies of deep ICP-Coring are developed.This principle and technology consists of five parts:in-situ pressurepreserved coring(IPP-Coring),in-situ substance-preserved coring(ISP-Coring),in-situ temperaturepreserved coring(ITP-Coring),in-situ light-preserved coring(ILP-Coring),and in-situ moisturepreserved coring(IMP-Coring).The theory and technology of temperature and pressure reconstruction at different occurrence depths and in different environments are proposed,and prototype trial production was completed by following the principle of displacement and tests based on the in-situ reconstructed environment.The notable advances are as follows:(1)Deep in-situ coring system:A pressure-preserved controller with an ultimate bearing capacity greater than 140 MPa,highperformance(temperature-resistant,pressure-resistant,and low thermally conductive)temperaturepreserved materials,an active temperature control system,and high-barrier quality-preserved membrane materials were developed;a deep ICP-Coring capacity calibration platform was independently developed,a deep in-situ coring technology system was developed,and the acquisition of deep in-situ cores was realized.(2)In-situ storage displacement system:Following the dual-circuit hydraulic design idea,a single-drive source push-pull composite grabbing mechanism was designed;the design of the overall structure for the deep in-situ displacement storage system and ultrahigh pressure cabin structure was completed,which could realize docking the coring device and core displacement in the in-situ reconstructed environment.(3)Test analysis system:A noncontact acoustic-electric-magnetic test system was developed under the in-situ reconstructed environment,and the errors between the test results and traditional contact test results were mostly less than 10%;a detachable deep in-situ core true triaxial test system was developed,which could perform loading tests for deep in-situ cores.The relevant technological achievements were successfully applied to the exploration and development of deep resources,such as deep mines,deep-sea natural gas hydrates,and deep oil and gas.The research results provide technical and equipment support for the construction of a theoretical system for deep in-situ rock mechanics,the development of deep earth resources and energy,and the scientific exploration of different layers and occurrence depths(deep and ultradeep)of the Earth.展开更多
Straw return is a promising strategy for managing soil organic carbon(SOC)and improving yield stability.However,the optimal straw return strategy for sustainable crop production in the wheat(Triticum aestivum L.)-cott...Straw return is a promising strategy for managing soil organic carbon(SOC)and improving yield stability.However,the optimal straw return strategy for sustainable crop production in the wheat(Triticum aestivum L.)-cotton(Gossypium hirsutum L.)cropping system remains uncertain.The objective of this study was to quantify the long-term(10 years)impact of carbon(C)input on SOC sequestration,soil aggregation and crop yields in a wheat-cotton cropping system in the Yangtze River Valley,China.Five treatments were arranged with a single-factor randomized design as follows:no straw return(Control),return of wheat straw only(Wt),return of cotton straw only(Ct),return of 50%wheat and 50%cotton straw(Wh-Ch)and return of 100%wheat and 100%cotton straw(Wt-Ct).In comparison to the Control,the SOC content increased by 8.4 to 20.2%under straw return.A significant linear positive correlation between SOC sequestration and C input(1.42-7.19 Mg ha^(−1)yr^(−1))(P<0.05)was detected.The percentages of aggregates of sizes>2 and 1-2 mm at the 0-20 cm soil depth were also significantly elevated under straw return,with the greatest increase of the aggregate stability in the Wt-Ct treatment(28.1%).The average wheat yields increased by 12.4-36.0%and cotton yields increased by 29.4-73.7%,and significantly linear positive correlations were also detected between C input and the yields of wheat and cotton.The average sustainable yield index(SYI)reached a maximum value of 0.69 when the C input was 7.08 Mg ha^(−1)yr^(−1),which was close to the maximum value(SYI of 0.69,C input of 7.19 Mg ha^(−1)yr^(-1))in the Wt-Ct treatment.Overall,the return of both wheat and cotton straw was the best strategy for improving SOC sequestration,soil aggregation,yields and their sustainability in the wheat-cotton rotation system.展开更多
Physiral and Rehabilitation Medicine (PRM) is the Medicine of Functioning in light of health conditions, under consideration of the person and in interaction with the environment[1-2].PRM focuses on the application of...Physiral and Rehabilitation Medicine (PRM) is the Medicine of Functioning in light of health conditions, under consideration of the person and in interaction with the environment[1-2].PRM focuses on the application of rehabilitation, the third health strategy which complements the preventive and curative health strategies.Thanks to the increasing survival of people after injury and formerly conditions as well as aging populations and an associated increase in chronic conditions, PRM as the leader of the rehabilitation will, over the next decades, assume an ever more important role in the health care systems worldwide.展开更多
With the progress of the times,the number of college students is growing exponentially.But the students who enter the university are various and have their own advantages and disadvantages.Among them,the polarization ...With the progress of the times,the number of college students is growing exponentially.But the students who enter the university are various and have their own advantages and disadvantages.Among them,the polarization of students'English level is particularly obvious and serious.Therefore,in view of the contradiction between"not enough to learn"and"unable to learn",this paper makes a preliminary exploration on the pragmatic acquisition mode of College English teaching based on multimedia and network social environment.This paper mainly discusses and analyzes the concept of pragmatic acquisition mode and about how to implement it in practical teaching.In addition,this paper is only for reference in the English teaching industry.展开更多
With the increasing depth of coal mining,the requirements for coring devices that maintain pressure are increasing.To adapt to the special environment in deep coal seams and improve the accuracy of testing gas content...With the increasing depth of coal mining,the requirements for coring devices that maintain pressure are increasing.To adapt to the special environment in deep coal seams and improve the accuracy of testing gas content,a low-disturbance pressure-preserving corer was developed.The measurement of gas content using this corer was analyzed.The coring test platform was used to complete a coring function test.A pressurized core with a diameter of 50 mm was obtained.The pressure was 0.15 MPa,which was equal to the pressure of the liquid column of the cored layer,indicating that the corer can be successfully used in a mud environment.Next,a pressure test of the corer was conducted.The results showed that under conditions of low pressure(8 MPa)and high pressure(25 MPa),the internal pressure of the corer remained stable for more than 1 h,indicating that the corer has good ability to maintain pressure.Therefore,the corer can be applied at deep coal mine sites.The results of this research can be used to promote the safe exploitation of deep coal mines and the exploitation of methane resources in coalbeds.展开更多
Background: Zearalenone(ZEN) is an estrogenic mycotoxin that is primarily produced by Fusarium fungi and has been proven to affect the reproductive capacity of many species to varying degrees. The present experiment w...Background: Zearalenone(ZEN) is an estrogenic mycotoxin that is primarily produced by Fusarium fungi and has been proven to affect the reproductive capacity of many species to varying degrees. The present experiment was designed to study the maternal persistent effects of zearalenone toxicity in gestating sows on growth and muscle development of their offsprings, and the alleviation of zearalenone toxicity by modified halloysite nanotubes(MHNTs).Methods: Eighteen sows were fed with one of three dietary treatments that included the following:(1) a control diet,(2) a contaminated grain diet(with 50 % moldy corn, 2.77 mg/kg ZEN), and(3) a contaminated grain diet(with 50 %moldy corn, 2.76 mg/kg ZEN) + 1 % MHNTs. Each sow was exclusively fed its experimental diets from 35 to 70 d of gestation at a total of 2 kg daily. Muscle samples were collected from six piglets per treatment at birth, weaning and finishing.Results: The results showed that feeding the sows with the ZEN-contaminated diets from 35 to 70 d of gestation decreased the ADG, ADFI and G:F of their offsprings(P < 0.05). The muscle fiber numbers in the newborn, weaning and growing-finishing pigs and the muscle fiber diameters at birth and weaning were also decreased by maternal ZEN exposure(P < 0.05). The expressions of IGF-I, IGF-II, Myf-5 and Mstn at birth and IGF-II, Pax7, Myf-5 and Myo D1 at weaning were altered by feeding gestating sows with ZEN-contaminated diets(P < 0.05). The MHNTs reduced most of the ZEN-induced toxic effects: the ADG and ADFI on growth performance, the muscle fiber numbers at weaning and finishing and the muscle fiber diameters at weaning(P < 0.05). The expression levels of IGF-II and Mstn in newborn piglets and IGF-II and Myf-5 in weaning piglets were also prevented by adding 1 % MHNTs(P < 0.05).Conclusions: The present study demonstrated that the offsprings of sows fed with ZEN-contaminated diets from 35 to 70 day of gestation exhibited weakening on growth performance, physiological changes in their muscle fibers and alterations of m RNA expression in their muscle tissues, and also indicated that MHNTs prevented most of the ZENinduced weakening in the muscle tissues.展开更多
Current gradient-index(GRIN)lens based proximal-driven intracoronary optical coherence tomography(ICOCT)probes consist of a spacer and a GRIN lens with large gradient constant.This design provides great flexibility to...Current gradient-index(GRIN)lens based proximal-driven intracoronary optical coherence tomography(ICOCT)probes consist of a spacer and a GRIN lens with large gradient constant.This design provides great flexibility to control beam profiles,but the spacer length should be well controlled to obtain desired beam profiles and thus it sets an obstacle in mass catheter fabrication.Besides,although GRIN lens with large gradient constant can provide tight focus spot,it has short depth of focus and fast-expanded beam which leads to poor lateral resolution for deep tissue.In this paper,a type of spacer-removed probe is demonstrated with a small gradient constant GRIN lens.This design simplifies the fabrica-tion process and is suitable for mass production.The output beam of the catheter is a narrow nearly collimated light beam,referred to as pencil beam here.The full width at half maximum beam size varies from 35.1μm to 75.3μm in air over 3-mm range.Probe design principles are elaborated with probe/catheter fabrication and performance test.The in vivo imaging of the catheter was verified by a clinical ICOCT system.Those results prove that this novel pencil-beam scanning catheter is potentially a good choice for ICOCT systems.展开更多
Ischemic heart diseases are the leading cause of death with increasing numbers of patients worldwide.Despite advances in revascularization techniques,angiogenic therapies remain highly attractive.Physiological ischemi...Ischemic heart diseases are the leading cause of death with increasing numbers of patients worldwide.Despite advances in revascularization techniques,angiogenic therapies remain highly attractive.Physiological ischemia training,which is first proposed in our laboratory,refers to reversible ischemia training of normal skeletal muscles by using a tourniquet or isometric contraction to cause physiologic ischemia for about 4 weeks for the sake of triggering molecular and cellular mechanisms to promote angiogenesis and formation of collateral vessels and protect remote ischemia areas.Physiological ischemia training therapy augments angiogenesis in the ischemic myocardium by inducing differential expression of proteins involved in energy metabolism,cell migration,protein folding,and generation.It upregulates the expressions of vascular endothelial growth factor,and induces angiogenesis,protects the myocardium when infarction occurs by increasing circulating endothelial progenitor cells and enhancing their migration,which is in accordance with physical training in heart disease rehabilitation.These findings may lead to a new approach of therapeutic angiogenesis for patients with ischemic heart diseases.On the basis of the promising results in animal studies,studies were also conducted in patients with coronary artery disease without any adverse effect in vivo,indicating that physiological ischemia training therapy is a safe,effective and non-invasive angiogenic approach for cardiovascular rehabilitation.Preconditioning is considered to be the most protective intervention against myocardial ischemia-reperfusion injury to date.Physiological ischemia training is different from preconditioning.This review summarizes the preclinical and clinical data of physiological ischemia training and its difference from preconditioning.展开更多
Objective: The aim of this study was to improve muscle flaps and to evaluate surgical outcomes with the use of a novel specialized retractor, which is a surgical instrument used to locate and shape a bony seat for min...Objective: The aim of this study was to improve muscle flaps and to evaluate surgical outcomes with the use of a novel specialized retractor, which is a surgical instrument used to locate and shape a bony seat for minimally invasive cochlear implantation.Methods: 50 patients aged 1 e75 years with sensorineural hearing loss who required cochlear implantation were recruited. A small incision(<3 cm) was made, and the novel specialized retractor was used in the study group during cochlear implantation. The incision length, surgical outcomes and operative time were recorded and analyzed.Results: The incision length, total operative time and drilling bony time were shorter in the study group than in the control group(P < 0.05, respectively). All patients recovered well after the surgery without any severe complications.Conclusion: The use of a novel specialized retractor standardized the surgical processes of cochlear implantation. The retractor helped locate and control the size of the bony well during bone drilling. The tool reduced the technical difficulty and improved the efficacy of this minimally invasive operation.展开更多
During heat treatment or mechanical processing,most polycrystalline materials experience grain growth,which significantly affects their mechanical properties.Microstructure simulation on a mesoscopic scale is an impor...During heat treatment or mechanical processing,most polycrystalline materials experience grain growth,which significantly affects their mechanical properties.Microstructure simulation on a mesoscopic scale is an important way of studying grain growth.A key research focus of this type of method has long been how to efficiently and accurately simulate the grain growth caused by a non-uniform temperature field with temperature gradients.In this work,we propose an improved 3D Monte Carlo Potts(MCP)method to quantitatively study the relationship between non-uniform temperature fields and final grain morphologies.Properties of the aluminum alloy AA6061-T6 are used to establish a trial calculation model and to verify the algorithms with existing experimental results in literature.The detailed grain growth process of the 6061-T6 aluminum alloy under different temperature fields is then obtained,and grain morphologies at various positions are analyzed.Results indicate that while absolute temperature and duration time are the primary factors determining the final grain size,the temperature gradient also has strong influence on the grain morphologies.The relationships between temperatures,temperature gradients and grain growth process have been established.The proposed MCP algorithm can be applied to different types of materials when the proper parameters are used.展开更多
Autoencoder-based rating prediction methods with external attributes have received wide attention due to their ability to accurately capture users'preferences.However,existing methods still have two significant li...Autoencoder-based rating prediction methods with external attributes have received wide attention due to their ability to accurately capture users'preferences.However,existing methods still have two significant limitations:i)External attributes are often unavailable in the real world due to privacy issues,leading to low quality of representations;and ii)existing methods lack considering complex associations in users'rating behaviors during the encoding process.To meet these challenges,this paper innovatively proposes an inherent-attribute-aware dual-graph autoencoder,named IADGAE,for rating prediction.To address the low quality of representations due to the unavailability of external attributes,we propose an inherent attribute perception module that mines inductive user active patterns and item popularity patterns from users'rating behaviors to strengthen user and item representations.To exploit the complex associations hidden in users’rating behaviors,we design an encoder on the item-item co-occurrence graph to capture the co-occurrence frequency features among items.Moreover,we propose a dual-graph feature encoder framework to simultaneously encode and fuse the high-order representations learned from the user-item rating graph and item-item co-occurrence graph.Extensive experiments on three real datasets demonstrate that IADGAE is effective and outperforms existing rating prediction methods,which achieves a significant improvement of 4.51%~41.63%in the RMSE metric.展开更多
Quality of life and functional recovery after burn injury is the final goal of burn care,especially as most of burn patients survive the injury due to advanced medical science.However,dysfunction,disfigurement,contrac...Quality of life and functional recovery after burn injury is the final goal of burn care,especially as most of burn patients survive the injury due to advanced medical science.However,dysfunction,disfigurement,contractures,psychological problems and other discomforts due to burns and the consequent scars are common,and physical therapy and occupational therapy provide alternative treatments for these problems of burn patients.This guideline,organized by the Chinese Burn Association and Chinese Association of Burn Surgeons aims to emphasize the importance of team work in burn care and provide a brief introduction of the outlines of physical and occupational therapies during burn treatment,which is suitable for the current medical circumstances of China.It can be used as the start of the tools for burn rehabilitation.展开更多
●Nematode abundance and footprint show unimodal patterns with precipitation levels.●MAP governed nematode diversity along the precipitation gradient of agroecosystem.●Soil pH determined nematode abundance and footp...●Nematode abundance and footprint show unimodal patterns with precipitation levels.●MAP governed nematode diversity along the precipitation gradient of agroecosystem.●Soil pH determined nematode abundance and footprint in low precipitation levels.Precipitation plays a crucial role in global biodiversity change across terrestrial ecosystems.Precipitation is proven to affect soil organism diversity in natural ecosystems.However,how precipitation change affects the function of the soil nematode community remains unclear in cropland ecosystems.Here,we tested soil nematode communities from different precipitation sites(300 mm to 900 mm)of the agricultural ecosystem.The abundance of total nematodes,fungivores,and plant parasites,together with the footprint of fungivores was significantly affected by mean annual precipitation(MAP)in cropland ecosystem.Plant parasites diversity and footprint showed negative relationships with MAP.The random forest suggested plant parasite footprint was the most responsive to MAP.The structural equation model revealed that MAP affected nematode abundance and footprint indirectly via soil pH;nematode diversity was affected by MAP directly.We conclude that precipitation could act as the main selection stress for nematode diversity among the large gradient of agricultural ecosystems.However,the soil pH may act as a stress factor in determining nematode community and carbon flow in the soil food web.Our study emphasized that using nematode value by trophic group would provide a deep understanding of nematode response to precipitation in cropland ecosystems.展开更多
1.Introduction Due to the severe toxicity of heavy metal ions,human health and eco-system are threatened even at ultra-low concentrations[1].Specially,Pb^(2+)arouses more significant concern as its bio-accumulation se...1.Introduction Due to the severe toxicity of heavy metal ions,human health and eco-system are threatened even at ultra-low concentrations[1].Specially,Pb^(2+)arouses more significant concern as its bio-accumulation seriously affects brain development,reproductive systems,and cardiovascular function,consequently resulting in an irreversible damage.According to World Health Organization(WHO),the maximum allowable Pb^(2+)con-centration on the surface water should be<0.01 mg/L.Thus,consid-ering such deleterious and carcinogenic effects,the Pb^(2+)amount should be monitored to guarantee the water environment safety.Conventional methods always need complicate pretreatment.展开更多
The Five-hundred-meter Aperture Spherical radio Telescope(FAST)is the world’s largest single-dish radio telescope.Its large reflecting surface achieves unprecedented sensitivity but is prone to damage,such as dents a...The Five-hundred-meter Aperture Spherical radio Telescope(FAST)is the world’s largest single-dish radio telescope.Its large reflecting surface achieves unprecedented sensitivity but is prone to damage,such as dents and holes,caused by naturally-occurring falling objects.Hence,the timely and accurate detection of surface defects is crucial for FAST’s stable operation.Conventional manual inspection involves human inspectors climbing up and examining the large surface visually,a time-consuming and potentially unreliable process.To accelerate the inspection process and increase its accuracy,this work makes the first step towards automating the inspection of FAST by integrating deep-learning techniques with drone technology.First,a drone flies over the surface along a predetermined route.Since surface defects significantly vary in scale and show high inter-class similarity,directly applying existing deep detectors to detect defects on the drone imagery is highly prone to missing and misidentifying defects.As a remedy,we introduce cross-fusion,a dedicated plug-in operation for deep detectors that enables the adaptive fusion of multi-level features in a point-wise selective fashion,depending on local defect patterns.Consequently,strong semantics and fine-grained details are dynamically fused at different positions to support the accurate detection of defects of various scales and types.Our AI-powered drone-based automated inspection is time-efficient,reliable,and has good accessibility,which guarantees the long-term and stable operation of FAST.展开更多
基金supported by the National Natural Science Foundation of China,No.81971133Liaoning Key Research and Development Project,No.2021JH2/10300059Liaoning Revitalization Talents Prograrn,No.XLYC2002109(all to GL)。
文摘Loss of neurons and disruption of neural circuits are associated with many neurological diseases,including neurodegenerative diseases and mental disorders.The most prevalent pathological feature of neurodegenerative diseases is the aggregate loss of certain neuronal populations.For example,the loss of dopamine(DA)neurons in the substantia nigra pars compacta has been defined as a pathological hallmark of Parkinson’s disease(PD;Kamath et al.,2022).
基金the National Natural Science Foundation of China(No.51827901)the Program for Guangdong Introducing Innovative and Enterpreneurial Teams(No.2019ZT08G315)Shenzhen Key Research Projects(No.JSGG20220831105002005).
文摘With the depletion of shallow resources,the exploration of deep earth resources has become a global strategy.The study of the different patterns in the physical mechanical properties of rocks at different occurrence depths is the basis for exploring deep into the earth,with the core and premise being the acquisition and testing of deep in-situ core specimens.Based on the original idea of deep in-situ condition preserved coring(ICP-Coring)and testing,combined with theoretical modeling,numerical analysis,test platform development,indoor testing and engineering application,the principles and technologies of deep ICP-Coring are developed.This principle and technology consists of five parts:in-situ pressurepreserved coring(IPP-Coring),in-situ substance-preserved coring(ISP-Coring),in-situ temperaturepreserved coring(ITP-Coring),in-situ light-preserved coring(ILP-Coring),and in-situ moisturepreserved coring(IMP-Coring).The theory and technology of temperature and pressure reconstruction at different occurrence depths and in different environments are proposed,and prototype trial production was completed by following the principle of displacement and tests based on the in-situ reconstructed environment.The notable advances are as follows:(1)Deep in-situ coring system:A pressure-preserved controller with an ultimate bearing capacity greater than 140 MPa,highperformance(temperature-resistant,pressure-resistant,and low thermally conductive)temperaturepreserved materials,an active temperature control system,and high-barrier quality-preserved membrane materials were developed;a deep ICP-Coring capacity calibration platform was independently developed,a deep in-situ coring technology system was developed,and the acquisition of deep in-situ cores was realized.(2)In-situ storage displacement system:Following the dual-circuit hydraulic design idea,a single-drive source push-pull composite grabbing mechanism was designed;the design of the overall structure for the deep in-situ displacement storage system and ultrahigh pressure cabin structure was completed,which could realize docking the coring device and core displacement in the in-situ reconstructed environment.(3)Test analysis system:A noncontact acoustic-electric-magnetic test system was developed under the in-situ reconstructed environment,and the errors between the test results and traditional contact test results were mostly less than 10%;a detachable deep in-situ core true triaxial test system was developed,which could perform loading tests for deep in-situ cores.The relevant technological achievements were successfully applied to the exploration and development of deep resources,such as deep mines,deep-sea natural gas hydrates,and deep oil and gas.The research results provide technical and equipment support for the construction of a theoretical system for deep in-situ rock mechanics,the development of deep earth resources and energy,and the scientific exploration of different layers and occurrence depths(deep and ultradeep)of the Earth.
基金supported by the National Natural Science Foundation of China(32071968)the Jiangsu Agricultural Science and Technology Innovation Fund,China(CX(22)2015))the Jiangsu Collaborative Innovation Center for Modern Crop Production,China。
文摘Straw return is a promising strategy for managing soil organic carbon(SOC)and improving yield stability.However,the optimal straw return strategy for sustainable crop production in the wheat(Triticum aestivum L.)-cotton(Gossypium hirsutum L.)cropping system remains uncertain.The objective of this study was to quantify the long-term(10 years)impact of carbon(C)input on SOC sequestration,soil aggregation and crop yields in a wheat-cotton cropping system in the Yangtze River Valley,China.Five treatments were arranged with a single-factor randomized design as follows:no straw return(Control),return of wheat straw only(Wt),return of cotton straw only(Ct),return of 50%wheat and 50%cotton straw(Wh-Ch)and return of 100%wheat and 100%cotton straw(Wt-Ct).In comparison to the Control,the SOC content increased by 8.4 to 20.2%under straw return.A significant linear positive correlation between SOC sequestration and C input(1.42-7.19 Mg ha^(−1)yr^(−1))(P<0.05)was detected.The percentages of aggregates of sizes>2 and 1-2 mm at the 0-20 cm soil depth were also significantly elevated under straw return,with the greatest increase of the aggregate stability in the Wt-Ct treatment(28.1%).The average wheat yields increased by 12.4-36.0%and cotton yields increased by 29.4-73.7%,and significantly linear positive correlations were also detected between C input and the yields of wheat and cotton.The average sustainable yield index(SYI)reached a maximum value of 0.69 when the C input was 7.08 Mg ha^(−1)yr^(−1),which was close to the maximum value(SYI of 0.69,C input of 7.19 Mg ha^(−1)yr^(-1))in the Wt-Ct treatment.Overall,the return of both wheat and cotton straw was the best strategy for improving SOC sequestration,soil aggregation,yields and their sustainability in the wheat-cotton rotation system.
文摘Physiral and Rehabilitation Medicine (PRM) is the Medicine of Functioning in light of health conditions, under consideration of the person and in interaction with the environment[1-2].PRM focuses on the application of rehabilitation, the third health strategy which complements the preventive and curative health strategies.Thanks to the increasing survival of people after injury and formerly conditions as well as aging populations and an associated increase in chronic conditions, PRM as the leader of the rehabilitation will, over the next decades, assume an ever more important role in the health care systems worldwide.
基金2020 The subject of Educational Science in Heilongjiang Province:Studies on cultural conflicts in English flipped classes.(GJB1320065)2020 The subject of Educational Science in Heilongjiang Province:A Study on Metaphorical Translation Strategies and The Teaching Applications in Belt and road Political and Economic Texts(GJC1318022).
文摘With the progress of the times,the number of college students is growing exponentially.But the students who enter the university are various and have their own advantages and disadvantages.Among them,the polarization of students'English level is particularly obvious and serious.Therefore,in view of the contradiction between"not enough to learn"and"unable to learn",this paper makes a preliminary exploration on the pragmatic acquisition mode of College English teaching based on multimedia and network social environment.This paper mainly discusses and analyzes the concept of pragmatic acquisition mode and about how to implement it in practical teaching.In addition,this paper is only for reference in the English teaching industry.
基金supported by the National Natural Science Foundation of China(No.51827901)the National Natural Science Foundation of China(No.52225403)+1 种基金the Program for Guangdong Introducing Innovative and Entrepreneurial Teams of China(No.2019ZT08G315)the Sichuan Science and Technology Program of China(No.2023NSFSC0780).
文摘With the increasing depth of coal mining,the requirements for coring devices that maintain pressure are increasing.To adapt to the special environment in deep coal seams and improve the accuracy of testing gas content,a low-disturbance pressure-preserving corer was developed.The measurement of gas content using this corer was analyzed.The coring test platform was used to complete a coring function test.A pressurized core with a diameter of 50 mm was obtained.The pressure was 0.15 MPa,which was equal to the pressure of the liquid column of the cored layer,indicating that the corer can be successfully used in a mud environment.Next,a pressure test of the corer was conducted.The results showed that under conditions of low pressure(8 MPa)and high pressure(25 MPa),the internal pressure of the corer remained stable for more than 1 h,indicating that the corer has good ability to maintain pressure.Therefore,the corer can be applied at deep coal mine sites.The results of this research can be used to promote the safe exploitation of deep coal mines and the exploitation of methane resources in coalbeds.
基金supported by National Basic Research Program (2012CB124703)the China Agriculture Research System (CARS-36)Program for Innovative Research Team of Universities in Heilongjiang Province (2012TD003)
文摘Background: Zearalenone(ZEN) is an estrogenic mycotoxin that is primarily produced by Fusarium fungi and has been proven to affect the reproductive capacity of many species to varying degrees. The present experiment was designed to study the maternal persistent effects of zearalenone toxicity in gestating sows on growth and muscle development of their offsprings, and the alleviation of zearalenone toxicity by modified halloysite nanotubes(MHNTs).Methods: Eighteen sows were fed with one of three dietary treatments that included the following:(1) a control diet,(2) a contaminated grain diet(with 50 % moldy corn, 2.77 mg/kg ZEN), and(3) a contaminated grain diet(with 50 %moldy corn, 2.76 mg/kg ZEN) + 1 % MHNTs. Each sow was exclusively fed its experimental diets from 35 to 70 d of gestation at a total of 2 kg daily. Muscle samples were collected from six piglets per treatment at birth, weaning and finishing.Results: The results showed that feeding the sows with the ZEN-contaminated diets from 35 to 70 d of gestation decreased the ADG, ADFI and G:F of their offsprings(P < 0.05). The muscle fiber numbers in the newborn, weaning and growing-finishing pigs and the muscle fiber diameters at birth and weaning were also decreased by maternal ZEN exposure(P < 0.05). The expressions of IGF-I, IGF-II, Myf-5 and Mstn at birth and IGF-II, Pax7, Myf-5 and Myo D1 at weaning were altered by feeding gestating sows with ZEN-contaminated diets(P < 0.05). The MHNTs reduced most of the ZEN-induced toxic effects: the ADG and ADFI on growth performance, the muscle fiber numbers at weaning and finishing and the muscle fiber diameters at weaning(P < 0.05). The expression levels of IGF-II and Mstn in newborn piglets and IGF-II and Myf-5 in weaning piglets were also prevented by adding 1 % MHNTs(P < 0.05).Conclusions: The present study demonstrated that the offsprings of sows fed with ZEN-contaminated diets from 35 to 70 day of gestation exhibited weakening on growth performance, physiological changes in their muscle fibers and alterations of m RNA expression in their muscle tissues, and also indicated that MHNTs prevented most of the ZENinduced weakening in the muscle tissues.
基金financial supports from the National Natural Science Foundation of China(Grant No.81927805)Shenzhen Municipal Science and Technology Plan Project,China(Grant No.JCYJ20160427183803458)。
文摘Current gradient-index(GRIN)lens based proximal-driven intracoronary optical coherence tomography(ICOCT)probes consist of a spacer and a GRIN lens with large gradient constant.This design provides great flexibility to control beam profiles,but the spacer length should be well controlled to obtain desired beam profiles and thus it sets an obstacle in mass catheter fabrication.Besides,although GRIN lens with large gradient constant can provide tight focus spot,it has short depth of focus and fast-expanded beam which leads to poor lateral resolution for deep tissue.In this paper,a type of spacer-removed probe is demonstrated with a small gradient constant GRIN lens.This design simplifies the fabrica-tion process and is suitable for mass production.The output beam of the catheter is a narrow nearly collimated light beam,referred to as pencil beam here.The full width at half maximum beam size varies from 35.1μm to 75.3μm in air over 3-mm range.Probe design principles are elaborated with probe/catheter fabrication and performance test.The in vivo imaging of the catheter was verified by a clinical ICOCT system.Those results prove that this novel pencil-beam scanning catheter is potentially a good choice for ICOCT systems.
基金supported by grants from Nantong City(No.BK2014040 to Jun Ni and No.HS2012057 to Hongjian Lu)Chinese National Science Fund of China(No.81070181 to Xiao Lu)
文摘Ischemic heart diseases are the leading cause of death with increasing numbers of patients worldwide.Despite advances in revascularization techniques,angiogenic therapies remain highly attractive.Physiological ischemia training,which is first proposed in our laboratory,refers to reversible ischemia training of normal skeletal muscles by using a tourniquet or isometric contraction to cause physiologic ischemia for about 4 weeks for the sake of triggering molecular and cellular mechanisms to promote angiogenesis and formation of collateral vessels and protect remote ischemia areas.Physiological ischemia training therapy augments angiogenesis in the ischemic myocardium by inducing differential expression of proteins involved in energy metabolism,cell migration,protein folding,and generation.It upregulates the expressions of vascular endothelial growth factor,and induces angiogenesis,protects the myocardium when infarction occurs by increasing circulating endothelial progenitor cells and enhancing their migration,which is in accordance with physical training in heart disease rehabilitation.These findings may lead to a new approach of therapeutic angiogenesis for patients with ischemic heart diseases.On the basis of the promising results in animal studies,studies were also conducted in patients with coronary artery disease without any adverse effect in vivo,indicating that physiological ischemia training therapy is a safe,effective and non-invasive angiogenic approach for cardiovascular rehabilitation.Preconditioning is considered to be the most protective intervention against myocardial ischemia-reperfusion injury to date.Physiological ischemia training is different from preconditioning.This review summarizes the preclinical and clinical data of physiological ischemia training and its difference from preconditioning.
基金supported by the Special Funds for National Excellent Doctoral Dissertation of Higher Education from the Ministry of Education (Project Number: 2007B67)the National Major Research Project (2014CB943003)
文摘Objective: The aim of this study was to improve muscle flaps and to evaluate surgical outcomes with the use of a novel specialized retractor, which is a surgical instrument used to locate and shape a bony seat for minimally invasive cochlear implantation.Methods: 50 patients aged 1 e75 years with sensorineural hearing loss who required cochlear implantation were recruited. A small incision(<3 cm) was made, and the novel specialized retractor was used in the study group during cochlear implantation. The incision length, surgical outcomes and operative time were recorded and analyzed.Results: The incision length, total operative time and drilling bony time were shorter in the study group than in the control group(P < 0.05, respectively). All patients recovered well after the surgery without any severe complications.Conclusion: The use of a novel specialized retractor standardized the surgical processes of cochlear implantation. The retractor helped locate and control the size of the bony well during bone drilling. The tool reduced the technical difficulty and improved the efficacy of this minimally invasive operation.
基金The authors would like to acknowledge the financial support from China Postdoctoral Science Foundation Project(2018M641128)the National Key Research and Development Program of China(2018YFB0703500).
文摘During heat treatment or mechanical processing,most polycrystalline materials experience grain growth,which significantly affects their mechanical properties.Microstructure simulation on a mesoscopic scale is an important way of studying grain growth.A key research focus of this type of method has long been how to efficiently and accurately simulate the grain growth caused by a non-uniform temperature field with temperature gradients.In this work,we propose an improved 3D Monte Carlo Potts(MCP)method to quantitatively study the relationship between non-uniform temperature fields and final grain morphologies.Properties of the aluminum alloy AA6061-T6 are used to establish a trial calculation model and to verify the algorithms with existing experimental results in literature.The detailed grain growth process of the 6061-T6 aluminum alloy under different temperature fields is then obtained,and grain morphologies at various positions are analyzed.Results indicate that while absolute temperature and duration time are the primary factors determining the final grain size,the temperature gradient also has strong influence on the grain morphologies.The relationships between temperatures,temperature gradients and grain growth process have been established.The proposed MCP algorithm can be applied to different types of materials when the proper parameters are used.
基金supported in part by National Natural Science Foundation of China(U21B2015,61972300)in part by Young Scientists Fund of the National Natural Science Foundation of China(62202356)+1 种基金in part by Young Talent Fund of Association for Science and Technology in Shaanxi(20220113)in part by Intelligent Financial Software Engineering New Technology Joint Laboratory Project(99901220858)。
文摘Autoencoder-based rating prediction methods with external attributes have received wide attention due to their ability to accurately capture users'preferences.However,existing methods still have two significant limitations:i)External attributes are often unavailable in the real world due to privacy issues,leading to low quality of representations;and ii)existing methods lack considering complex associations in users'rating behaviors during the encoding process.To meet these challenges,this paper innovatively proposes an inherent-attribute-aware dual-graph autoencoder,named IADGAE,for rating prediction.To address the low quality of representations due to the unavailability of external attributes,we propose an inherent attribute perception module that mines inductive user active patterns and item popularity patterns from users'rating behaviors to strengthen user and item representations.To exploit the complex associations hidden in users’rating behaviors,we design an encoder on the item-item co-occurrence graph to capture the co-occurrence frequency features among items.Moreover,we propose a dual-graph feature encoder framework to simultaneously encode and fuse the high-order representations learned from the user-item rating graph and item-item co-occurrence graph.Extensive experiments on three real datasets demonstrate that IADGAE is effective and outperforms existing rating prediction methods,which achieves a significant improvement of 4.51%~41.63%in the RMSE metric.
文摘Quality of life and functional recovery after burn injury is the final goal of burn care,especially as most of burn patients survive the injury due to advanced medical science.However,dysfunction,disfigurement,contractures,psychological problems and other discomforts due to burns and the consequent scars are common,and physical therapy and occupational therapy provide alternative treatments for these problems of burn patients.This guideline,organized by the Chinese Burn Association and Chinese Association of Burn Surgeons aims to emphasize the importance of team work in burn care and provide a brief introduction of the outlines of physical and occupational therapies during burn treatment,which is suitable for the current medical circumstances of China.It can be used as the start of the tools for burn rehabilitation.
基金supported by the National Science and Technology Fundamental Resources Investigation Program of China(2018FY100300)the National Natural Science Foundation of China(No.41807046)the Youth Talent Promotion Project of Jilin Province(QT202230).
文摘●Nematode abundance and footprint show unimodal patterns with precipitation levels.●MAP governed nematode diversity along the precipitation gradient of agroecosystem.●Soil pH determined nematode abundance and footprint in low precipitation levels.Precipitation plays a crucial role in global biodiversity change across terrestrial ecosystems.Precipitation is proven to affect soil organism diversity in natural ecosystems.However,how precipitation change affects the function of the soil nematode community remains unclear in cropland ecosystems.Here,we tested soil nematode communities from different precipitation sites(300 mm to 900 mm)of the agricultural ecosystem.The abundance of total nematodes,fungivores,and plant parasites,together with the footprint of fungivores was significantly affected by mean annual precipitation(MAP)in cropland ecosystem.Plant parasites diversity and footprint showed negative relationships with MAP.The random forest suggested plant parasite footprint was the most responsive to MAP.The structural equation model revealed that MAP affected nematode abundance and footprint indirectly via soil pH;nematode diversity was affected by MAP directly.We conclude that precipitation could act as the main selection stress for nematode diversity among the large gradient of agricultural ecosystems.However,the soil pH may act as a stress factor in determining nematode community and carbon flow in the soil food web.Our study emphasized that using nematode value by trophic group would provide a deep understanding of nematode response to precipitation in cropland ecosystems.
基金supported by grants from the Major Program of the National Natural Science Foundation of China(No.21590813)the National Natural Science Foundation of China(No.22006039,52100128,22122807)+4 种基金the Key Project of the National Ministry of Science and Technology(No.2016YFCU204204)the Natural Science Foundation of Shandong Province(No.ZR2020QB141)the Natural Science Foundation of Shanghai(No.21ZR1425700)the China Postdoctoral Science Foundation(No.2019M661412)supported by Supercomputing Center of Dalian University of Technology.
文摘1.Introduction Due to the severe toxicity of heavy metal ions,human health and eco-system are threatened even at ultra-low concentrations[1].Specially,Pb^(2+)arouses more significant concern as its bio-accumulation seriously affects brain development,reproductive systems,and cardiovascular function,consequently resulting in an irreversible damage.According to World Health Organization(WHO),the maximum allowable Pb^(2+)con-centration on the surface water should be<0.01 mg/L.Thus,consid-ering such deleterious and carcinogenic effects,the Pb^(2+)amount should be monitored to guarantee the water environment safety.Conventional methods always need complicate pretreatment.
基金financially supported by the National Natural Science Foundation of China(No.62101032)the Postdoctoral Science Foundation of China(Nos.2021M690015,2022T150050)the Beijing Institute of Technology Research Fund Program for Young Scholars(No.3040011182111).
文摘The Five-hundred-meter Aperture Spherical radio Telescope(FAST)is the world’s largest single-dish radio telescope.Its large reflecting surface achieves unprecedented sensitivity but is prone to damage,such as dents and holes,caused by naturally-occurring falling objects.Hence,the timely and accurate detection of surface defects is crucial for FAST’s stable operation.Conventional manual inspection involves human inspectors climbing up and examining the large surface visually,a time-consuming and potentially unreliable process.To accelerate the inspection process and increase its accuracy,this work makes the first step towards automating the inspection of FAST by integrating deep-learning techniques with drone technology.First,a drone flies over the surface along a predetermined route.Since surface defects significantly vary in scale and show high inter-class similarity,directly applying existing deep detectors to detect defects on the drone imagery is highly prone to missing and misidentifying defects.As a remedy,we introduce cross-fusion,a dedicated plug-in operation for deep detectors that enables the adaptive fusion of multi-level features in a point-wise selective fashion,depending on local defect patterns.Consequently,strong semantics and fine-grained details are dynamically fused at different positions to support the accurate detection of defects of various scales and types.Our AI-powered drone-based automated inspection is time-efficient,reliable,and has good accessibility,which guarantees the long-term and stable operation of FAST.
