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Enhancing Offensive Language Detection with Data Augmentation and Knowledge Distillation
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作者 jiawen deng Zhuang Chen +5 位作者 Hao Sun Zhexin Zhang Jincenzi Wu Satoshi Nakagawa Fuji Ren Minlie Huang 《Research》 SCIE EI CSCD 2024年第2期29-40,共12页
Offensive language detection has received important attention and plays a crucial role in promoting healthy communication on social platforms,as well as promoting the safe deployment of large language models.Training ... Offensive language detection has received important attention and plays a crucial role in promoting healthy communication on social platforms,as well as promoting the safe deployment of large language models.Training data is the basis for developing detectors;however,the available offense-related dataset in Chinese is severely limited in terms of data scale and coverage when compared to English resources.This significantly affects the accuracy of Chinese offensive language detectors in practical applications,especially when dealing with hard cases or out-of-domain samples.To alleviate the limitations posed by available datasets,we introduce AugCOLD(Augmented Chinese Offensive Language Dataset),a large-scale unsupervised dataset containing 1 million samples gathered by data crawling and model generation.Furthermore,we employ a multiteacher distillation framework to enhance detection performance with unsupervised data.That is,we build multiple teachers with publicly accessible datasets and use them to assign soft labels to AugCOLD.The soft labels serve as a bridge for knowledge to be distilled from both AugCOLD and multiteacher to the student network,i.e.,the final offensive detector.We conduct experiments on multiple public test sets and our well-designed hard tests,demonstrating that our proposal can effectively improve the generalization and robustness of the offensive language detector. 展开更多
关键词 COLD dealing LIMITATIONS
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多靶向沉默里氏木霉碳代谢阻遏物对纤维素酶活性和表达的调控研究 被引量:3
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作者 邓嘉雯 高云雨 +3 位作者 刘旭坤 张珂珂 钟路遥 田生礼 《微生物学报》 CAS CSCD 北大核心 2019年第4期730-743,共14页
【目的】构建多靶向siRNA表达载体对里氏木霉碳阻遏抑制因子CRE1、CRE2、CRE3和CRE4进行同时多靶向siRNA干扰,以研究其对里氏木霉纤维素酶基因表达的调控作用。【方法】根据此前研究筛选出沉默cre1、cre2、cre3和cre4基因的4个最佳siRN... 【目的】构建多靶向siRNA表达载体对里氏木霉碳阻遏抑制因子CRE1、CRE2、CRE3和CRE4进行同时多靶向siRNA干扰,以研究其对里氏木霉纤维素酶基因表达的调控作用。【方法】根据此前研究筛选出沉默cre1、cre2、cre3和cre4基因的4个最佳siRNA序列,设计并构建了A多靶向表达载体,另根据cre1、cre2、cre3和cre4基因中所含有的5个共有序列设计并构建了B多靶向表达载体,将两者转化至里氏木霉QM9414。经筛选后分别在48 h和120 h对各转化子进行纤维素酶酶活力测试(CMC活力测试和滤纸酶酶活力测试)及利用qPCR检测相关基因的表达。【结果】通过RT-qPCR测定结果表明,两种表达载体均可同时抑制里氏木霉的分解代谢物阻遏基因cre1、cre2、cre3和cre4的表达,纤维素酶活力比出发菌株明显升高,多靶向抑制菌株的CMC酶活和滤纸酶活比出发菌株平均提高了1.95倍和2.66倍。纤维素酶基因cbh1和egl1的表达水平比出发菌株也有明显提升,平均提高了3.83倍和3.95倍。纤维素酶相关基因xyr1的表达水平与出发菌株相比也明显上升,平均提高了2.78倍。【结论】多靶向沉默里氏木霉的碳代谢阻遏蛋白有利于解除葡萄糖效应,提高非还原糖的利用,从而提高纤维素酶的产量,使纤维素酶的表达得到更大的提升,为里氏木霉表达纤维素酶在分解代谢物阻遏基因调控方面提供了实验依据和新的技术思路。 展开更多
关键词 里氏木霉 RNA干扰 碳代谢阻遏物 纤维素酶
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The clinical effectiveness and safety of using epidermal growth factor,fibroblast growth factor and granulocyte-macrophage colony stimulating factor as therapeutics in acute skin wound healing:a systematic review and meta-analysis 被引量:3
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作者 Yating Wei Jiangfeng Li +7 位作者 Yao Huang Xun Lei Lijun Zhang Meifang Yin jiawen deng Xiaoyan Wang Xiaobing Fu Jun Wu 《Burns & Trauma》 SCIE 2022年第1期715-741,共27页
Background:Promoting wound healing is crucial to restore the vital barrier function of injured skin.Growth factor products including epidermal growth factor(EGF),fibroblast growth factor(FGF)and granulocyte-macrophage... Background:Promoting wound healing is crucial to restore the vital barrier function of injured skin.Growth factor products including epidermal growth factor(EGF),fibroblast growth factor(FGF)and granulocyte-macrophage colony stimulating factor(GM-CSF)have been used for decades although no systematic evaluation exists regarding their effectiveness and safety issues in treating acute skin wounds.This has resulted in a lack of guidelines and standards for proper application regimes.Therefore,this systematic review and meta-analysis was performed to critically evaluate the effectiveness and safety of these growth factors on skin acute wounds and provide guidelines for application regimes.Methods:We searched PubMed/Medline(1980-2020),Cochrane Library(1980-2020),Cochrane CENTRAL(from establishment to 2020),ClinicalTrials.gov(from establishment to 2020),Chinese Journal Full-text Database(CNKI,1994-2020),China Biology Medicine disc(CBM,1978-2019),Chinese Scientific Journal Database(VIP,1989-2020)andWanfang Database(WFDATA,1980-2019).Randomized controlled trials(RCTs),quasi-RCTs and controlled clinical trials treating patients with acute skin wounds from various causes and with those available growth factors were included.Results:A total of 7573 papers were identified through database searching;229 papers including 281 studies were kept after final screening.Administering growth factors significantly short-ened the healing time of acute skin wounds,including superficial burn injuries[mean differ-ence(MD)=−3.02;95%confidence interval(CI):−3.31∼−2.74;p<0.00001],deep burn injuries(MD=−5.63;95%CI:−7.10∼−4.17;p<0.00001),traumata and surgical wounds(MD=−4.50;95%CI:−5.55∼−3.44;p<0.00001).Growth factors increased the healing rate of acute skin wounds and decreased scar scores.The incidence of adverse reactions was lower in the growth factor treatment group than in the non-growth factor group.Conclusions:The studied growth factors not only are effective and safe for managing acute skin wounds,but also accelerate their healing with no severe adverse reactions. 展开更多
关键词 Growth factors Skin wounds META-ANALYSIS Wound healing
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Hierarchical Network with Label Embedding for Contextual Emotion Recognition 被引量:1
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作者 jiawen deng Fuji Ren 《Research》 SCIE EI CAS CSCD 2021年第1期103-111,共9页
Emotion recognition has been used widely in various applications such as mental health monitoring and emotional management.Usually,emotion recognition is regarded as a text classification task.Emotion recognition is a... Emotion recognition has been used widely in various applications such as mental health monitoring and emotional management.Usually,emotion recognition is regarded as a text classification task.Emotion recognition is a more complex problem,and the relations of emotions expressed in a text are nonnegligible.In this paper,a hierarchical model with label embedding is proposed for contextual emotion recognition.Especially,a hierarchical model is utilized to learn the emotional representation of a given sentence based on its contextual information.To give emotion correlation-based recognition,a label embedding matrix is trained by joint learning,which contributes to the final prediction.Comparison experiments are conducted on Chinese emotional corpus RenCECps,and the experimental results indicate that our approach has a satisfying performance in textual emotion recognition task. 展开更多
关键词 EMOTIONAL CONTEXTUAL HAS
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