Objective:To investigate the clinical efficacy and safety of percutaneous kyphoplasty at different surgical timings in the treatment of osteoporotic vertebral compression fracture(OVCF)based on the theory of“dynamic-...Objective:To investigate the clinical efficacy and safety of percutaneous kyphoplasty at different surgical timings in the treatment of osteoporotic vertebral compression fracture(OVCF)based on the theory of“dynamic-static integration”.Methods:Patients with OVCF who underwent percutaneous kyphoplasty in our hospital were selected and divided into Groups A,B,and C for those undergoing surgery within 7,7—21,and>21 days of fracture occurrence.The variations in the amount of bone cement injected,pre-and post-operative pain levels,functional activity,deformity correction of the injured vertebrae,bone cement leakage,and vertebral body height loss were compared among the three groups.Results:Regarding pain relief and functional activity,the postoperative Visual Analog Scale and Oswestry Disability Index scores of the three groups significantly improved.Furthermore,the deformities of the injured vertebrae in the three groups were significantly corrected,with Groups A and B exhibiting superior correction compared to Group C.Moreover,the bone cement leakage rates in groups A and C were higher than that in Group B.At the 3-month follow-up,the loss of vertebral height in Group C was significantly higher than those in groups A and B.Conclusion:Kyphoplasty is effective for OVCF treatment.Early surgery can effectively restore the vertebral height of the injured vertebra,reduce kyphosis,and reduce height loss of the injured vertebra after surgery;nevertheless,treatment within 1—3 weeks of the fracture can reduce the occurrence of bone cement leakage,making the surgery safer.Therefore,surgical treatment within 1—3 weeks of fracture is safer and can achieve satisfactory therapeutic effects.From the perspective of traditional Chinese medicine,PKP surgery can transform the fracture end from a micromotion state to a fixed state,which fully embodies the theory of“dynamic-static integration”.展开更多
The basic indexes of all-optical integrated photonic circuits include high-density integration,ultrafast response and ultralow energy consumption.Traditional methods mainly adopt conventional micro/nano-structures.The...The basic indexes of all-optical integrated photonic circuits include high-density integration,ultrafast response and ultralow energy consumption.Traditional methods mainly adopt conventional micro/nano-structures.The overall size of the circuit is large,usually reaches hundreds of microns.Besides,it is difficult to balance the ultrafast response and ultra-low energy consumption problem,and the crosstalk between two traditional devices is difficult to overcome.Here,we propose and experimentally demonstrate an approach based on inverse design method to realize a high-density,ultrafast and ultra-low energy consumption integrated photonic circuit with two all-optical switches controlling the input states of an all-optical XOR logic gate.The feature size of the whole circuit is only 2.5μm×7μm,and that of a single device is 2μm×2μm.The distance between two adjacent devices is as small as 1.5μm,within wavelength magnitude scale.Theoretical response time of the circuit is 150 fs,and the threshold energy is within 10 fJ/bit.We have also considered the crosstalk problem.The circuit also realizes a function of identifying two-digit logic signal results.Our work provides a new idea for the design of ultrafast,ultra-low energy consumption all-optical devices and the implementation of high-density photonic integrated circuits.展开更多
By integrating the traditional power grid with information and communication technology, smart grid achieves dependable, efficient, and flexible grid data processing. The smart meters deployed on the user side of the ...By integrating the traditional power grid with information and communication technology, smart grid achieves dependable, efficient, and flexible grid data processing. The smart meters deployed on the user side of the smart grid collect the users' power usage data on a regular basis and upload it to the control center to complete the smart grid data acquisition. The control center can evaluate the supply and demand of the power grid through aggregated data from users and then dynamically adjust the power supply and price, etc. However, since the grid data collected from users may disclose the user's electricity usage habits and daily activities, privacy concern has become a critical issue in smart grid data aggregation. Most of the existing privacy-preserving data collection schemes for smart grid adopt homomorphic encryption or randomization techniques which are either impractical because of the high computation overhead or unrealistic for requiring a trusted third party.展开更多
Due to the"trade-off"effect between the high water adsorption and low stability under high Relative Humidity of polymer matrix,fabrication of resistive-type polymer-based humidity sensors with a wide impedan...Due to the"trade-off"effect between the high water adsorption and low stability under high Relative Humidity of polymer matrix,fabrication of resistive-type polymer-based humidity sensors with a wide impedance response and excellent stability in high relative humidity remains a great challenge.Aim at solving that,a novel polymeric humidity sensing matrix,specifically a tadpole-shaped,polyhedral oligomeric silsesquioxane(POSS)containing block copolymers(BCPs)of POSS-poly(methyl methacrylate)-poly styrene(POSS-PMMA-SPS)were proposed.This novel BCP was synthesized using atom transfer radical polymerization(ATRP)employing a two-step approach,and following post sulfonation,a series of sulfonated BCPs(POSS-PMMA-SPS)with different sulfonation degree was obtained.The subject humidity sensors were produced using different sulfonated BCPs employing a dip-coating technique,and three wide-impedance response humidity sensors were produced.Each of these sensors exhibited an excellent humidity-sensing response of mo re than 104 within the humidity range from 11%to 95%RH.In particular,the humidity sensor S-6 that had a proper degree of sulfonation presented a relatively fast response(t90%of 11 s and 80 s in both the water adsorption and desorption processes),and superior repeatability for more than 30 days.展开更多
基金supported by the National Natural Science Foundation of China(82374493).
文摘Objective:To investigate the clinical efficacy and safety of percutaneous kyphoplasty at different surgical timings in the treatment of osteoporotic vertebral compression fracture(OVCF)based on the theory of“dynamic-static integration”.Methods:Patients with OVCF who underwent percutaneous kyphoplasty in our hospital were selected and divided into Groups A,B,and C for those undergoing surgery within 7,7—21,and>21 days of fracture occurrence.The variations in the amount of bone cement injected,pre-and post-operative pain levels,functional activity,deformity correction of the injured vertebrae,bone cement leakage,and vertebral body height loss were compared among the three groups.Results:Regarding pain relief and functional activity,the postoperative Visual Analog Scale and Oswestry Disability Index scores of the three groups significantly improved.Furthermore,the deformities of the injured vertebrae in the three groups were significantly corrected,with Groups A and B exhibiting superior correction compared to Group C.Moreover,the bone cement leakage rates in groups A and C were higher than that in Group B.At the 3-month follow-up,the loss of vertebral height in Group C was significantly higher than those in groups A and B.Conclusion:Kyphoplasty is effective for OVCF treatment.Early surgery can effectively restore the vertebral height of the injured vertebra,reduce kyphosis,and reduce height loss of the injured vertebra after surgery;nevertheless,treatment within 1—3 weeks of the fracture can reduce the occurrence of bone cement leakage,making the surgery safer.Therefore,surgical treatment within 1—3 weeks of fracture is safer and can achieve satisfactory therapeutic effects.From the perspective of traditional Chinese medicine,PKP surgery can transform the fracture end from a micromotion state to a fixed state,which fully embodies the theory of“dynamic-static integration”.
基金the National Key Research and Development Program of China under Grant No.2018YFB2200403the National Natural Science Foundation of China under Grant Nos.11734001,91950204,92150302.
文摘The basic indexes of all-optical integrated photonic circuits include high-density integration,ultrafast response and ultralow energy consumption.Traditional methods mainly adopt conventional micro/nano-structures.The overall size of the circuit is large,usually reaches hundreds of microns.Besides,it is difficult to balance the ultrafast response and ultra-low energy consumption problem,and the crosstalk between two traditional devices is difficult to overcome.Here,we propose and experimentally demonstrate an approach based on inverse design method to realize a high-density,ultrafast and ultra-low energy consumption integrated photonic circuit with two all-optical switches controlling the input states of an all-optical XOR logic gate.The feature size of the whole circuit is only 2.5μm×7μm,and that of a single device is 2μm×2μm.The distance between two adjacent devices is as small as 1.5μm,within wavelength magnitude scale.Theoretical response time of the circuit is 150 fs,and the threshold energy is within 10 fJ/bit.We have also considered the crosstalk problem.The circuit also realizes a function of identifying two-digit logic signal results.Our work provides a new idea for the design of ultrafast,ultra-low energy consumption all-optical devices and the implementation of high-density photonic integrated circuits.
基金supported in part by the National Natural Science Foundation of China under Grant No.61972371Youth Innovation Promotion Association of Chinese Academy of Sciences(CAS)under Grant No.Y202093.
文摘By integrating the traditional power grid with information and communication technology, smart grid achieves dependable, efficient, and flexible grid data processing. The smart meters deployed on the user side of the smart grid collect the users' power usage data on a regular basis and upload it to the control center to complete the smart grid data acquisition. The control center can evaluate the supply and demand of the power grid through aggregated data from users and then dynamically adjust the power supply and price, etc. However, since the grid data collected from users may disclose the user's electricity usage habits and daily activities, privacy concern has become a critical issue in smart grid data aggregation. Most of the existing privacy-preserving data collection schemes for smart grid adopt homomorphic encryption or randomization techniques which are either impractical because of the high computation overhead or unrealistic for requiring a trusted third party.
基金the financial support from China's Social Science Research Project(No.06CJL010 and No.08CJL025)Nankai University's 985 Research Innovation Project(No.985TNC20070202)the Social Science Large Grant Project(No.07JJD790137)supported by the Ministry of Education
基金supported by Natural Science and Technology Agency of Shaanxi Province(No.2019KW-024)fundamentalresearch funds for the central universities(No.310201911 fz050)the Open Fund for Key Lab of Guangdong High Property and Functional Macromolecular Materials(No.20190015)。
文摘Due to the"trade-off"effect between the high water adsorption and low stability under high Relative Humidity of polymer matrix,fabrication of resistive-type polymer-based humidity sensors with a wide impedance response and excellent stability in high relative humidity remains a great challenge.Aim at solving that,a novel polymeric humidity sensing matrix,specifically a tadpole-shaped,polyhedral oligomeric silsesquioxane(POSS)containing block copolymers(BCPs)of POSS-poly(methyl methacrylate)-poly styrene(POSS-PMMA-SPS)were proposed.This novel BCP was synthesized using atom transfer radical polymerization(ATRP)employing a two-step approach,and following post sulfonation,a series of sulfonated BCPs(POSS-PMMA-SPS)with different sulfonation degree was obtained.The subject humidity sensors were produced using different sulfonated BCPs employing a dip-coating technique,and three wide-impedance response humidity sensors were produced.Each of these sensors exhibited an excellent humidity-sensing response of mo re than 104 within the humidity range from 11%to 95%RH.In particular,the humidity sensor S-6 that had a proper degree of sulfonation presented a relatively fast response(t90%of 11 s and 80 s in both the water adsorption and desorption processes),and superior repeatability for more than 30 days.
