To investigate the effect of deep foundation pit excavation on the stability of retaining structure, a subway stationin the city of Jinan was selected as a project, and a FLAC3D-based three dimensional model was devel...To investigate the effect of deep foundation pit excavation on the stability of retaining structure, a subway stationin the city of Jinan was selected as a project, and a FLAC3D-based three dimensional model was developed fornumerical simulation. The horizontal displacement of the retaining structure, the axial force of the support, andthe vertical displacement of the column were studied and compared to the collected data from the field. The findingsindicate that when the foundation pit is excavated, the maximum deformation of the retaining structure progressivelydecreases from the top, the distortion of the retaining structure gradually rises, and the final maximumdeformation is around 17 meters deep. In each layer of support, the largest axial force support is located in thefirst reinforced concrete support;the uplift of the pit bottom caused by soil unloading plays a primary role in thevertical displacement of the column, and the column exhibits an upward trend under all construction conditions.When compared to the measured data, the generated findings are comparable and the fluctuation trend is extremelyconsistent. The findings of this article may give technical direction for the development of subway stationswith a comparable engineering basis.展开更多
Urinary incontinence(UI)is a disease that quietly yet seriously impacts women's health and represents a global health burden that is often neglected.This study aims to systematically assess the prevalence and dyna...Urinary incontinence(UI)is a disease that quietly yet seriously impacts women's health and represents a global health burden that is often neglected.This study aims to systematically assess the prevalence and dynamics of female UI in China,and can inform further policies and have international implications.This study used three nationwide investigations:A national cross-sectional survey in 2021;another nationwide cross-sectional survey in 2006;and data regarding the institutions and physicians providing pelvic floor rehabilitation services from 2005 to 2019.The weighted prevalence of female UI and its subtypes,including stress UI(SUI),urgency UI(UUI),and mixed UI(MUI),were estimated as primary outcomes.Knowledge,attitude and care-seeking behaviors of UI were evaluated.It was found that the weighted prevalence of female UI was 16.0%(95%CI,13.3%–19.1%)with SUI remaining the predominant subtype(7.0%)in 2021,followed by MUI(6.5%)and UUI(1.9%).The estimated absolute number of Chinese adult women with UI was 85.8 million in 2021.52.7%(95%CI,45.9%–59.4%)of women were aware that UI was a medical condition,and only 10.1%of women with UI sought health care.After 15 years of development,there were 8400 pelvic floor rehabilitation institutions and nearly 10,000 relevant physicians in ChinaDthey were found to be associated with UI prevalence.The UI prevalence in China was significantly lower in 2021 compared to that in 2006.Despite the achievement,UI remains a public health problem,especially given China's fast aging and three-child policy.More innovations,especially those that can facilitate care seeking,are needed to address this prevalent yet treatable condition.展开更多
基金supported by the National Natural Science Foundation of China(51774199).
文摘To investigate the effect of deep foundation pit excavation on the stability of retaining structure, a subway stationin the city of Jinan was selected as a project, and a FLAC3D-based three dimensional model was developed fornumerical simulation. The horizontal displacement of the retaining structure, the axial force of the support, andthe vertical displacement of the column were studied and compared to the collected data from the field. The findingsindicate that when the foundation pit is excavated, the maximum deformation of the retaining structure progressivelydecreases from the top, the distortion of the retaining structure gradually rises, and the final maximumdeformation is around 17 meters deep. In each layer of support, the largest axial force support is located in thefirst reinforced concrete support;the uplift of the pit bottom caused by soil unloading plays a primary role in thevertical displacement of the column, and the column exhibits an upward trend under all construction conditions.When compared to the measured data, the generated findings are comparable and the fluctuation trend is extremelyconsistent. The findings of this article may give technical direction for the development of subway stationswith a comparable engineering basis.
基金supported by the National Key Research and Development Program of China(2021YFC2701300,2023YFC2706000 and 2018YFC2002201)the National Natural Science Foundation of China(72104247)the National High Level Hospital Clinical Research Funding(2022-PUMCH-B-087,2022-PUMCH-A-023)。
文摘Urinary incontinence(UI)is a disease that quietly yet seriously impacts women's health and represents a global health burden that is often neglected.This study aims to systematically assess the prevalence and dynamics of female UI in China,and can inform further policies and have international implications.This study used three nationwide investigations:A national cross-sectional survey in 2021;another nationwide cross-sectional survey in 2006;and data regarding the institutions and physicians providing pelvic floor rehabilitation services from 2005 to 2019.The weighted prevalence of female UI and its subtypes,including stress UI(SUI),urgency UI(UUI),and mixed UI(MUI),were estimated as primary outcomes.Knowledge,attitude and care-seeking behaviors of UI were evaluated.It was found that the weighted prevalence of female UI was 16.0%(95%CI,13.3%–19.1%)with SUI remaining the predominant subtype(7.0%)in 2021,followed by MUI(6.5%)and UUI(1.9%).The estimated absolute number of Chinese adult women with UI was 85.8 million in 2021.52.7%(95%CI,45.9%–59.4%)of women were aware that UI was a medical condition,and only 10.1%of women with UI sought health care.After 15 years of development,there were 8400 pelvic floor rehabilitation institutions and nearly 10,000 relevant physicians in ChinaDthey were found to be associated with UI prevalence.The UI prevalence in China was significantly lower in 2021 compared to that in 2006.Despite the achievement,UI remains a public health problem,especially given China's fast aging and three-child policy.More innovations,especially those that can facilitate care seeking,are needed to address this prevalent yet treatable condition.