We demonstrate a diode pumped Yb:LuVO4 laser that can be passively Q-switched by a Cr^(4+):YAG saturable absorber having an initial transmission as high as 99.3%.A maximum pulsed output power of 2.35 W is generat...We demonstrate a diode pumped Yb:LuVO4 laser that can be passively Q-switched by a Cr^(4+):YAG saturable absorber having an initial transmission as high as 99.3%.A maximum pulsed output power of 2.35 W is generated at a repetition rate of 285.7 kHz,approaching or very near the intrinsic upper limit imposed by the recovery time of the Cr^(4+):YAG saturable absorber,and the resulting pulse energy,duration and peak power are,respectively,8.2μJ,39.2ns and 0.209kW.展开更多
A comprehensive investigation is carried out to compare the spectroscopic properties, absorption saturation behaviors and lasing properties of a Yb ion in tetragonal LuPO4 and LuVO4 isomorphic crystals. Significant di...A comprehensive investigation is carried out to compare the spectroscopic properties, absorption saturation behaviors and lasing properties of a Yb ion in tetragonal LuPO4 and LuVO4 isomorphic crystals. Significant distinctions are revealed in many aspects of the lasing behavior for the Yb ion doped in the two crystal hosts, and Yb:LuPO_4 proves to be superior to Yb:LuVO4 since it enables efficient laser action to be much more easily achieved. With a 0.6 mm thick crystal plate of Yb:LuPO4, an output power of 3.30 W can be generated with an optical–optical conversion efficiency of 50.8%; whereas with a 2 mm long miniature crystal rod, the output power produced can reach 8.35 W with an optical–optical conversion efficiency of 46.7%.展开更多
BACKGROUND Immunoglobulin D(IgD)multiple myeloma(MM)is a rare subtype of MM and commonly occurs in younger subjects but at a later stage of the International Staging System(ISS)when admitted.As a special type of IgD m...BACKGROUND Immunoglobulin D(IgD)multiple myeloma(MM)is a rare subtype of MM and commonly occurs in younger subjects but at a later stage of the International Staging System(ISS)when admitted.As a special type of IgD myeloma,IgD-λ/λbiclonal MM is rarer.Its serum protein electrophoresis and serum immunofixation electrophoresis(IFE)might find no anomalies even if the bone marrow(BM)examination is performed.Thus,it is easy to miss the diagnosis.CASE SUMMARY A 62-year-old man diagnosed as IgD-λ/λmyeloma(ISS stage III)was admitted with fatigue and weight loss.The physical examination suggested an anemic face,a few moist rales at the left lung base,and mild concave edema in both lower extremities.Laboratory examinations showed the elevated creatinine levels,β2-microglobulin,lactic dehydrogenase,and erythrocyte sedimentation rate,while the decreased neutrophils,granulocytes,and hemoglobin.In the serum protein electrophoresis,there appeared two inconspicuous M-spikes.Serum IFE indicated an over-representation of lambda light chain and yielded two monoclonal bands inλregion,but only one corresponding heavy chain band in the antisera to IgD region.The BM histology and BM cytology both supported the diagnosis of IgD-λ/λmyeloma.CONCLUSION This case highlights the differential clinical manifestations and laboratory findings of IgD-λ/λmyeloma to help minimize the chance of misdiagnosis.展开更多
基金Supported by the National Natural Science Foundation of China under Grant No 11574170
文摘We demonstrate a diode pumped Yb:LuVO4 laser that can be passively Q-switched by a Cr^(4+):YAG saturable absorber having an initial transmission as high as 99.3%.A maximum pulsed output power of 2.35 W is generated at a repetition rate of 285.7 kHz,approaching or very near the intrinsic upper limit imposed by the recovery time of the Cr^(4+):YAG saturable absorber,and the resulting pulse energy,duration and peak power are,respectively,8.2μJ,39.2ns and 0.209kW.
基金Project supported by the National Natural Science Foundation of China(Grant No.11574170)
文摘A comprehensive investigation is carried out to compare the spectroscopic properties, absorption saturation behaviors and lasing properties of a Yb ion in tetragonal LuPO4 and LuVO4 isomorphic crystals. Significant distinctions are revealed in many aspects of the lasing behavior for the Yb ion doped in the two crystal hosts, and Yb:LuPO_4 proves to be superior to Yb:LuVO4 since it enables efficient laser action to be much more easily achieved. With a 0.6 mm thick crystal plate of Yb:LuPO4, an output power of 3.30 W can be generated with an optical–optical conversion efficiency of 50.8%; whereas with a 2 mm long miniature crystal rod, the output power produced can reach 8.35 W with an optical–optical conversion efficiency of 46.7%.
基金National Natural Science Foundation of China,No.81500430 and No.U1304802Science and Technology Planning Project of Henan Province,No.192102310045,No.182102310544,No.182102310566,and No.182102310573Henan Medical Science and Technology Tackling Project,No.2018020320.
文摘BACKGROUND Immunoglobulin D(IgD)multiple myeloma(MM)is a rare subtype of MM and commonly occurs in younger subjects but at a later stage of the International Staging System(ISS)when admitted.As a special type of IgD myeloma,IgD-λ/λbiclonal MM is rarer.Its serum protein electrophoresis and serum immunofixation electrophoresis(IFE)might find no anomalies even if the bone marrow(BM)examination is performed.Thus,it is easy to miss the diagnosis.CASE SUMMARY A 62-year-old man diagnosed as IgD-λ/λmyeloma(ISS stage III)was admitted with fatigue and weight loss.The physical examination suggested an anemic face,a few moist rales at the left lung base,and mild concave edema in both lower extremities.Laboratory examinations showed the elevated creatinine levels,β2-microglobulin,lactic dehydrogenase,and erythrocyte sedimentation rate,while the decreased neutrophils,granulocytes,and hemoglobin.In the serum protein electrophoresis,there appeared two inconspicuous M-spikes.Serum IFE indicated an over-representation of lambda light chain and yielded two monoclonal bands inλregion,but only one corresponding heavy chain band in the antisera to IgD region.The BM histology and BM cytology both supported the diagnosis of IgD-λ/λmyeloma.CONCLUSION This case highlights the differential clinical manifestations and laboratory findings of IgD-λ/λmyeloma to help minimize the chance of misdiagnosis.