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Advancing oral cancer care:Insights from Tongluo Jiedu prescription
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作者 Chun-Yao Cheng Wen-Rui Hao +1 位作者 ju-chi liu Tzu-Hurng Cheng 《World Journal of Clinical Cases》 SCIE 2024年第35期6764-6769,共6页
This editorial highlights the study which investigated the potential of traditional Chinese medicine(TCM)as an adjunctive therapy in oral cancer management.The study included 80 patients with oral cancer to evaluate t... This editorial highlights the study which investigated the potential of traditional Chinese medicine(TCM)as an adjunctive therapy in oral cancer management.The study included 80 patients with oral cancer to evaluate the effects of the Tongluo Jiedu prescription on inflammatory stress markers,peripheral blood T-cell subsets,and overall immune function.The results indicated that Tongluo Jiedu substantially enhances immune function and reduces oxidative stress,thereby aiding in patient recovery and potentially minimizing treatment-related complications.This editorial discusses the broader implications of these findings for oral cancer care and emphasizes the importance of integrating TCM principles into modern oncology practices. 展开更多
关键词 Tongluo Jiedu prescription Oral cancer patients Immune function Oxidative stress Traditional Chinese medicine Adjunctive therapy
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Unraveling autophagy-related pathogenesis in active ulcerative colitis:A bioinformatics approach
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作者 Wen-Rui Hao Chun-Yao Cheng +1 位作者 ju-chi liu Tzu-Hurng Cheng 《World Journal of Clinical Cases》 SCIE 2024年第30期6335-6338,共4页
In this editorial,we provide commentary on the study by Gong et al.In this original research article,Gong et al employed a bioinformatics approach to investigate the involvement of autophagy in active ulcerative colit... In this editorial,we provide commentary on the study by Gong et al.In this original research article,Gong et al employed a bioinformatics approach to investigate the involvement of autophagy in active ulcerative colitis(UC).Through differential gene expression analysis,they identified 58 differentially expressed autophagy-related genes in UC patients compared to healthy controls.Notably,HSPA5,CASP1,SERPINA1,CX3CL1,and BAG3,were found to be upregulated in active UC patients,suggesting their significance as core autophagyrelated targets.Enrichment analysis unveiled associations with crucial signaling pathways and diseases such as middle cerebral artery occlusion and glomerulonephritis.Moreover,immune cell infiltration analysis revealed notable differences in immune cell composition between UC patients and healthy controls.These findings offer valuable insights into the role of autophagy in UC pathogenesis and potential therapeutic targets. 展开更多
关键词 Ulcerative colitis AUTOPHAGY BIOINFORMATICS PATHOGENESIS Therapeutic targets
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