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年龄相关性黄斑变性的脉络膜厚度评价(英文) 被引量:4
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作者 Erkan Unsal kadir eltutar +3 位作者 Ozen Ayranci Osmanbasoglu Sibel Zιrtιloglu Osman Kιzιlay Hulya Gungel 《国际眼科杂志》 CAS 2014年第9期1561-1566,共6页
目的:通过光学相干断层扫描(optical coherence tomography,OCT;RTVue 100-2;V 5.1,Optovue,Fremont,CA,USA)测量比较非新生血管性与新生血管性年龄相关性黄斑变性(age-related macular degeneration,AMD)黄斑中心凹下脉络膜厚度(subfov... 目的:通过光学相干断层扫描(optical coherence tomography,OCT;RTVue 100-2;V 5.1,Optovue,Fremont,CA,USA)测量比较非新生血管性与新生血管性年龄相关性黄斑变性(age-related macular degeneration,AMD)黄斑中心凹下脉络膜厚度(subfoveal choroidal thickness,SFCT),并分析脉络膜厚度(choroidal thickness,CT)对AMD新血管形成的影响。方法:本研究为回顾性、横断面研究。以单侧眼患有新生血管性AMD且对侧眼患有非新生血管性AMD的24例患者(48眼)作为研究组,选取年龄与眼轴长度相匹配的40例健康眼作为对照组。非新生血管性AMD亚组研究对象是黄斑区有玻璃疣和/或色素变化眼,而新生血管性AMD亚组研究对象是由于脉络膜新生血管而致视网膜下或视网膜内有渗出液和/或脂性渗出眼。运用OCT垂直测量外侧高反射线(视网膜色素上皮层)到脉络膜巩膜交界面间的距离。选取7个不同点进行脉络膜厚度测量,测量区域为距黄斑中心凹颞侧和鼻侧1500μm范围,测量间距为500μm。测量结果在亚组间进行统计学对比研究。结果:研究组患者平均年龄为72.4±8.97(60~82)岁,对照组受试者平均年龄为71.2±8.8(58~81)岁。新生血管性AMD组中平均SFCT明显大于非新生血管性AMD组的厚度(P<0.05)。非新生血管性AMD组中,平均SFCT与平均鼻、颞侧脉络膜厚度比较,差异无统计学意义(P>0.05);而新生血管性AMD组中,平均SFCT与平均鼻、颞侧脉络膜厚度比较,差异有统计学意义(P<0.05)。结论:运用OCT对脉络膜厚度进行测量,有助于理解AMD的病理生理机制。然而,仍需要大型前瞻性研究来探求新生血管性AMD中SFCT增厚的原因。 展开更多
关键词 脉络膜厚度 年龄相关性黄斑变性 光学相干断层扫描
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Ultrasound biomicroscopy in patients with unilateral pseudoexfoliation 被引量:2
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作者 Erkan ünsal kadir eltutar +2 位作者 Ilkay Muftuoglu Tulay Alpar Akcetin Yildiz Acar 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2015年第4期754-758,共5页
·AIM: To compare the anterior segment morphology evaluated using ultrasound biomicroscopy(UBM) in patients with clinical pseudoexfoliation syndrome(XFS)in one eye and no clinical XFS in the fellow eye.·METHO... ·AIM: To compare the anterior segment morphology evaluated using ultrasound biomicroscopy(UBM) in patients with clinical pseudoexfoliation syndrome(XFS)in one eye and no clinical XFS in the fellow eye.·METHODS: Thirty patients with unilateral XFS were included in the study. All patients underwent evaluation of their anterior segment using UBM with and without dilatation with 1% cyclopentolate. The anterior chamber depth(ACD), lens thickness(LT), anterior chamber angle(ACA), ciliary body thickness(CBT), scleral thickness(ST), trabeculae-ciliary processes distance(T-CPD), and iris-ciliary processes distance(I-CPD) were measured using UBM scans. All results between the eyes with clinical XFS and their fellow eyes without clinical XFS were then compared.·RESULTS: Before dilatation the eyes with XFS(4.350±0.531 mm) were found to have a significantly thicker lens(P =0.002) than the eyes without XFS(4.238 ±0.540 mm).In addition after dilatation, the eyes with XFS(4.310 ±0.500 mm) were found to have a significantly thicker lens than the eyes without XFS(4.160±0.480 mm)(P=0.019).The average ACD, for the group with XFS, comparing pre-dilatation(2.616 ±0.349 mm) and post-dilatation measurements(2.714±0.413) was found to be statistically increased(P =0.014). The average ACD, comparing pre-dilatation to post-dilatation measurements in patients without XFS(2.680±0.360),(2.720±0.500) was found to be statistically unchanged(P =0.450).·CONCLUSION: Crystalline lenses tended to be thicker in the eyes with clinical pseudoexfoliation than their fellow eyes without pseudoexfoliation. 展开更多
关键词 PSEUDOEXFOLIATION syndrome ULTRASONIC BIOMICROSCOPY ANTERIOR SEGMENT morphology
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鼻泪管探通术治疗先天性鼻泪管阻塞的疗效观察(英文) 被引量:1
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作者 Fadime Nuhoglu Ayse Tekin Buyrukcu +1 位作者 Fatma Esin Ozdemir kadir eltutar 《国际眼科杂志》 CAS 2013年第4期652-655,共4页
目的:研究探通术与灌溉对儿童先天性鼻泪管阻塞(congenital nasolacrimal duct obstruction,CNDO)的成功率及相关因素。方法:从2005/2011,患有CNDO的儿童235例261眼行鼻泪管探通术。患者按年龄分为3组:组1,131眼为12~24月龄;组2,82眼... 目的:研究探通术与灌溉对儿童先天性鼻泪管阻塞(congenital nasolacrimal duct obstruction,CNDO)的成功率及相关因素。方法:从2005/2011,患有CNDO的儿童235例261眼行鼻泪管探通术。患者按年龄分为3组:组1,131眼为12~24月龄;组2,82眼为24~48月龄;组3,48眼为48~120月龄。在全身麻醉下进行上、下泪小点探通术。术后1d;1、2wk;1、3mo进行随访。通过Mann Whitney U检验和卡方检验分析手术成功率与年龄的相关性。结果:儿童235例(女性122例,男性113例)的平均年龄为27.6±10.7(12~120)mo。3组患儿一次探通术后的成功率分别为90.1%、85.4%和47.6%,并且组1、组2成功率显著高于组3(P<0.05)。患儿53例(20.3%)再次行探通术,3组的成功率分别为:61.5%、58.3%和25.0%。结论:鼻泪管探通术是治疗CNDO的有效方法,特别是对于小于2岁的患儿。手术成功率随着年龄增加而降低,但是上下泪小管二次探通术可以提高术后效果。 展开更多
关键词 先天性 鼻泪管阻塞 治疗 探通术
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鼻泪管探通术治疗先天性鼻泪管阻塞的疗效研究(英文)
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作者 Fadime Nuhoglu Ayse Tekin Buyrukcu +1 位作者 Fatma Esin Ozdemir kadir eltutar 《国际眼科杂志》 CAS 2012年第10期1823-1826,共4页
目的:研究探通术与灌溉对儿童先天性鼻泪管阻塞(congenital nasolacrimal duct obstruction,CNDO) 的成功率及相关因素。方法:从2005/2011 年,患有CNDO的儿童235例261眼行鼻泪管探通术。患者按年龄分为3组:组1,131 眼为12 ~24月龄; 组2... 目的:研究探通术与灌溉对儿童先天性鼻泪管阻塞(congenital nasolacrimal duct obstruction,CNDO) 的成功率及相关因素。方法:从2005/2011 年,患有CNDO的儿童235例261眼行鼻泪管探通术。患者按年龄分为3组:组1,131 眼为12 ~24月龄; 组2,82 眼为>24~48 月龄;组3,48 眼为>48~120 月龄。在全身麻醉下进行上、下泪小点探通术。术后1d; 1,2wk;1,3mo进行随访。通过Mann Whitney U检验和卡方检验分析手术成功率与年龄的相关性。结果:儿童235例(女性122例,男性113例)的平均年龄为27. 6±10. 7(12~120)mo。3组患儿一次探通术后的成功率分别为90.1%、85.4%和47.6%,并且组1 、组2成功率显著高于组3(P<0.05)。患儿53例(20.3%)再次行探通术,3组的成功率分别为:61.5%、58.3%和25.0%。结论:鼻泪管探通术是治疗CNDO的有效方法,特别是对于小于2岁的患儿。手术成功率随着年龄增加而降低,但是上下泪小管二次探通术可以提高术后效果。 展开更多
关键词 先天性 鼻泪管阻塞 治疗 探通术
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Evaluation of the Changes in Anterior Segment Morphology with Ultrasound Biomicroscopy after Vitrectomy without Use of Tamponade in Pseudophakic Eyes
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作者 Erkan Ünsal kadir eltutar 《Open Journal of Ophthalmology》 2016年第4期210-220,共11页
Aim: In this study we investigated the changes in anterior segment morphology in pseudophakia patients that underwent ultrasound biomicroscopy (UBM) after pars plana vitrectomy (PPV) operation without use of tamponade... Aim: In this study we investigated the changes in anterior segment morphology in pseudophakia patients that underwent ultrasound biomicroscopy (UBM) after pars plana vitrectomy (PPV) operation without use of tamponade. Method: Pseudophakic patients who undergo PPV were enrolled in this prospective study between October 2012 and April 2015. Study included patients in whom intraocular tamponade was not used during PPV operation. UBM measurements were performed both before and 10 days after the operation. Anterior chamber depth (ACD) was measured using axial images of anterior segment. Trabecular meshwork-iris angle (TIA), ciliary body thickness (CBT), sclera thickness (ST), trabecular meshwork-ciliary process distance (T-CPD), iris-ciliary processes distance (I-CPD), and iris thickness (IT) were measured at temporal quadrant based on radial section images of the angle. Values measured before and after the operation were statistically compared with each other. Results: This study included 30 patients (18 females, 12 males) that underwent an operation ultrasound biomicroscopy (UBM) after pars plana vitrectomy (PPV) operation without use of tamponade. Mean age was 69.6 ± 9.1 (55 - 85) years. Eighteen operations occurred on the left eye whereas twelve operations occurred on the right eye. CBT1, CBT2, CBT Max, T-CPD, and I-CPD were significantly decreased after operation when compared with the values of baseline (before) (p = 0.018, p = 0.012, p = 0.001, p = 0.033, p = 0.015, respectively). Other evaluated parameters did not show statistically significant changes after the operation (p > 0.05). Discussion: PPV results in significant changes in ciliary body morphology together with changes in anterior segment parameters in pseudophakic cases. 展开更多
关键词 Ultrasound Biomicroscopy (UBM) VITRECTOMY Pseudophakic Eye Anterior Segment Ciliary Body
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